Click here to switch to the map view.

The map label for this gene is aqpZ [H]

Identifier: 119357718

GI number: 119357718

Start: 2229660

End: 2230349

Strand: Reverse

Name: aqpZ [H]

Synonym: Cpha266_1922

Alternate gene names: 119357718

Gene position: 2230349-2229660 (Counterclockwise)

Preceding gene: 119357719

Following gene: 119357717

Centisome position: 71.17

GC content: 52.61

Gene sequence:

>690_bases
ATGAAAAAATATGTTGCGGAATTTGTCGGCACATTTTGGCTGGTTCTTGGCGGATGTGGAAGCGCAGTGCTTGCGGCTGC
TTTTCCTGATGTCGGGATCGGTCTGCTTGGAGTTTCTCTCGCCTTTGGGTTGACTGTTCTGACCATGGCATATGCTATAG
GACATATCTCCGGTTGTCATCTTAATCCTGCTGTTTCCGTTGGACTTTGGGCAGGCGGCCGTTTTCCGGCAAAAGAGTTA
CTGCCCTATATTTTCGCCCAGGTTGCTGGCGGCATTGCGGCAGGCGGCGTTCTTTTTCTGATCGCCAGCGGTAAAGCGGG
GTTTGATGTCCATGCGGGTTTTGCGTCAAACGGCTACGCCGAACACTCGCCCGGCGGATATTCGCTTATTTCAGCGCTTG
TTACCGAAGTGGTTATGACCATGATGTTTCTGCTTGTCATTCTCGGCTCAACGGATGGTCGGGCTCCGAAGGGAATGGCT
CCGATTGCTATCGGTCTTTGTCTTACCCTGATTCATCTTATCAGCATTCCCGTAACCAATACCTCAGTTAATCCTGCCCG
CAGTACAGGCGTTGCCGTTTTTGTCGGGGGATGGGCACTATCGCAGCTCTGGCTATTCTGGATTGCTCCGATTGCGGGAG
CGCTGGCAGGCGCAGTGATATACCGGTTTATTGGCGGAAGCGAAGAGTGA

Upstream 100 bases:

>100_bases
TTGGTTTCGAGACCAGAAAGATTCGTCTGTTATCTGGCGTAGCCGGAGGTTAAGGGAGGCGCTCAACTAATAATCACGTA
TAAAATAAAGGGGGAGGATC

Downstream 100 bases:

>100_bases
TAAATCGGTTGCATAACCGTTTTTTTTTACAGCGTTTCGCCATTCCTGTTGTTGACGGGAGTGGCGATTTTGTTTATGAC
TCTGAAACGGGTTTTTCTTT

Product: MIP family channel protein

Products: H2O [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKKYVAEFVGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAYAIGHISGCHLNPAVSVGLWAGGRFPAKEL
LPYIFAQVAGGIAAGGVLFLIASGKAGFDVHAGFASNGYAEHSPGGYSLISALVTEVVMTMMFLLVILGSTDGRAPKGMA
PIAIGLCLTLIHLISIPVTNTSVNPARSTGVAVFVGGWALSQLWLFWIAPIAGALAGAVIYRFIGGSEE

Sequences:

>Translated_229_residues
MKKYVAEFVGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAYAIGHISGCHLNPAVSVGLWAGGRFPAKEL
LPYIFAQVAGGIAAGGVLFLIASGKAGFDVHAGFASNGYAEHSPGGYSLISALVTEVVMTMMFLLVILGSTDGRAPKGMA
PIAIGLCLTLIHLISIPVTNTSVNPARSTGVAVFVGGWALSQLWLFWIAPIAGALAGAVIYRFIGGSEE
>Mature_229_residues
MKKYVAEFVGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAYAIGHISGCHLNPAVSVGLWAGGRFPAKEL
LPYIFAQVAGGIAAGGVLFLIASGKAGFDVHAGFASNGYAEHSPGGYSLISALVTEVVMTMMFLLVILGSTDGRAPKGMA
PIAIGLCLTLIHLISIPVTNTSVNPARSTGVAVFVGGWALSQLWLFWIAPIAGALAGAVIYRFIGGSEE

Specific function: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response

COG id: COG0580

COG function: function code G; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family [H]

Homologues:

Organism=Homo sapiens, GI37694062, Length=231, Percent_Identity=38.0952380952381, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI4502183, Length=226, Percent_Identity=35.8407079646018, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI4502179, Length=227, Percent_Identity=33.4801762114537, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI4755125, Length=230, Percent_Identity=30.8695652173913, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI4502181, Length=230, Percent_Identity=30.8695652173913, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI6912506, Length=225, Percent_Identity=31.1111111111111, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI86792455, Length=224, Percent_Identity=29.9107142857143, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI157266307, Length=240, Percent_Identity=30, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4826645, Length=247, Percent_Identity=27.5303643724696, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI22538420, Length=242, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI45446752, Length=208, Percent_Identity=30.2884615384615, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI297307120, Length=91, Percent_Identity=40.6593406593407, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4502187, Length=247, Percent_Identity=27.9352226720648, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI297307116, Length=91, Percent_Identity=40.6593406593407, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI297307118, Length=91, Percent_Identity=40.6593406593407, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787101, Length=223, Percent_Identity=71.7488789237668, Blast_Score=301, Evalue=2e-83,
Organism=Escherichia coli, GI1790362, Length=244, Percent_Identity=29.0983606557377, Blast_Score=81, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71993722, Length=236, Percent_Identity=29.6610169491525, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71992966, Length=234, Percent_Identity=29.4871794871795, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17558372, Length=233, Percent_Identity=29.1845493562232, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24652747, Length=225, Percent_Identity=36, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI45551084, Length=225, Percent_Identity=36, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24652751, Length=220, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19922038, Length=220, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17136672, Length=233, Percent_Identity=27.8969957081545, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24762342, Length=199, Percent_Identity=29.6482412060301, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550503, Length=229, Percent_Identity=27.5109170305677, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24762344, Length=227, Percent_Identity=28.6343612334802, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24762346, Length=227, Percent_Identity=28.6343612334802, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24762348, Length=227, Percent_Identity=28.6343612334802, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI20130305, Length=227, Percent_Identity=28.6343612334802, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012269
- InterPro:   IPR000425
- InterPro:   IPR022357 [H]

Pfam domain/function: PF00230 MIP [H]

EC number: NA

Molecular weight: Translated: 23385; Mature: 23385

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYVAEFVGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAYAIGHISGCH
CHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LNPAVSVGLWAGGRFPAKELLPYIFAQVAGGIAAGGVLFLIASGKAGFDVHAGFASNGYA
CCCHHEEEECCCCCCCHHHHHHHHHHHHHCCHHHCCEEEEEECCCCCCEEECCCCCCCCC
EHSPGGYSLISALVTEVVMTMMFLLVILGSTDGRAPKGMAPIAIGLCLTLIHLISIPVTN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
TSVNPARSTGVAVFVGGWALSQLWLFWIAPIAGALAGAVIYRFIGGSEE
CCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKYVAEFVGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAYAIGHISGCH
CHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LNPAVSVGLWAGGRFPAKELLPYIFAQVAGGIAAGGVLFLIASGKAGFDVHAGFASNGYA
CCCHHEEEECCCCCCCHHHHHHHHHHHHHCCHHHCCEEEEEECCCCCCEEECCCCCCCCC
EHSPGGYSLISALVTEVVMTMMFLLVILGSTDGRAPKGMAPIAIGLCLTLIHLISIPVTN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
TSVNPARSTGVAVFVGGWALSQLWLFWIAPIAGALAGAVIYRFIGGSEE
CCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O [Periplasm] [C]

Specific reaction: H2O [Periplasm] = H2O [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA