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The map label for this gene is yicO [C]

Identifier: 119357678

GI number: 119357678

Start: 2178110

End: 2179411

Strand: Direct

Name: yicO [C]

Synonym: Cpha266_1882

Alternate gene names: 119357678

Gene position: 2178110-2179411 (Clockwise)

Preceding gene: 119357675

Following gene: 119357679

Centisome position: 69.5

GC content: 51.54

Gene sequence:

>1302_bases
ATGCAATCCTACTTTAATTTTCAGGAACATCGCACCAGTTACCGGCAGGAATTTCTTGCCGGCATCACGACATTTTTCAC
CCTTTCCTACATCATCATCGTCAATCCGGCAATTCTTGCCGCTGCGGGCATTCCAAAAGGCGCTTCGATGACGGCAACCA
TCCTTACGGCGATCTTTGGTACGCTCCTGATGGGCGTCTATGCAAAGCGCCCCTTTGCCGTAGCCCCCTATATGGGAGAG
AATGCCTTTATTGCTTACACCGTGGTCCAGACGCTCGGCTACTCATGGCAGACTGCCATGGCGGCCATTTTTATCAGCGG
AGTGCTGTTTACCCTTATAACGCTCGCCGGACTGCGCGGATGGCTGGCCAAAGCCATTCCCGGATCGCTCAAACACAGTT
TTTCAGCCGGGATCGGCCTTTTTCTCGCCTTTCTCGGTCTTGGCAACATGGGAATCGTCACGCTCGGAGTACCCGGCGCT
CCGGTTCAACTGGGCAATATTGCACAACTCCCGGTACTCCTGAGCCTCGGAGGGTTGCTTGTTACTGCCGTACTGCTTAT
CCAGCGTATAACCGGAGCTATTCTTGCCGGTATGGTTGTTACGACAGCGGCATTTCTTCTGACGAGCCTTATTCCGCTCC
CTCAAACACTTTTCAGCATGCCGCCGTCGATTGAACCGATTTTCATGAAAATCGACATCAGGGGAGCATGGACATGGGGA
TTTGCCGGTGTAATCACCAGTGTCCTCGTCATGGATTTTGTCGATACCATGGGCACGCTTTTCGGATTGTCGTCCAGAGC
CAACCTTCTTGATGAAGAGGACAATCTTCCGGAAATCGAAAAGCCAATGCTCGTGGATGCGCTTTCAACCATTGCAGCAT
CACTTTTCGGAACAACAACGGCTGGCGTCTATATCGAGTCGGCGGCAGGCATCGAACAGGGTGGAAAAACAGGTTTTACT
GCGCTTGTTGTAGCCGCACTTTTTGCCCTTTCCCTGTTTTTTTCACCAGTACTGACCATCGTACCTCCTTTCGCCTACGG
CCCCGCTCTGGTTCTTGTCGGTATGTTCATGCTGCACTCTGTCACAAAATTCAACTTCAGCGACTACAGTGAGCTCCTGC
CCGCATTCCTCACCGTGGCATTGATTATTTTCACCTTCAACATCGGTGTCGGCATTACCGCGGGCTTTATATCCTACACC
GTACTCAAACTTTTTACCGGCAGGGCAGGAGAGGTGCATCCGGGCATGTGGATCCTTGCACTGCTCTCATTTACCTTTTA
TCTTTTCTACCCATACCATTAA

Upstream 100 bases:

>100_bases
TGCATCCGTTCCGAGCCTTTTAGCGTTTACAGCCCACCCTTTTCACTTGTAATGATTATCTTCAAAGCCTGGAGCCTCTG
ACTTTAAACGTTCATGATCA

Downstream 100 bases:

>100_bases
ACAGGAGAAAAGGATGTGCGCAAAACTGCGGATAGCCCAGACCGACTGCACCCTTGCCAATTTTGATGAAAATCTTGCAC
GGCACTGCGCCCTGACTGAA

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MQSYFNFQEHRTSYRQEFLAGITTFFTLSYIIIVNPAILAAAGIPKGASMTATILTAIFGTLLMGVYAKRPFAVAPYMGE
NAFIAYTVVQTLGYSWQTAMAAIFISGVLFTLITLAGLRGWLAKAIPGSLKHSFSAGIGLFLAFLGLGNMGIVTLGVPGA
PVQLGNIAQLPVLLSLGGLLVTAVLLIQRITGAILAGMVVTTAAFLLTSLIPLPQTLFSMPPSIEPIFMKIDIRGAWTWG
FAGVITSVLVMDFVDTMGTLFGLSSRANLLDEEDNLPEIEKPMLVDALSTIAASLFGTTTAGVYIESAAGIEQGGKTGFT
ALVVAALFALSLFFSPVLTIVPPFAYGPALVLVGMFMLHSVTKFNFSDYSELLPAFLTVALIIFTFNIGVGITAGFISYT
VLKLFTGRAGEVHPGMWILALLSFTFYLFYPYH

Sequences:

>Translated_433_residues
MQSYFNFQEHRTSYRQEFLAGITTFFTLSYIIIVNPAILAAAGIPKGASMTATILTAIFGTLLMGVYAKRPFAVAPYMGE
NAFIAYTVVQTLGYSWQTAMAAIFISGVLFTLITLAGLRGWLAKAIPGSLKHSFSAGIGLFLAFLGLGNMGIVTLGVPGA
PVQLGNIAQLPVLLSLGGLLVTAVLLIQRITGAILAGMVVTTAAFLLTSLIPLPQTLFSMPPSIEPIFMKIDIRGAWTWG
FAGVITSVLVMDFVDTMGTLFGLSSRANLLDEEDNLPEIEKPMLVDALSTIAASLFGTTTAGVYIESAAGIEQGGKTGFT
ALVVAALFALSLFFSPVLTIVPPFAYGPALVLVGMFMLHSVTKFNFSDYSELLPAFLTVALIIFTFNIGVGITAGFISYT
VLKLFTGRAGEVHPGMWILALLSFTFYLFYPYH
>Mature_433_residues
MQSYFNFQEHRTSYRQEFLAGITTFFTLSYIIIVNPAILAAAGIPKGASMTATILTAIFGTLLMGVYAKRPFAVAPYMGE
NAFIAYTVVQTLGYSWQTAMAAIFISGVLFTLITLAGLRGWLAKAIPGSLKHSFSAGIGLFLAFLGLGNMGIVTLGVPGA
PVQLGNIAQLPVLLSLGGLLVTAVLLIQRITGAILAGMVVTTAAFLLTSLIPLPQTLFSMPPSIEPIFMKIDIRGAWTWG
FAGVITSVLVMDFVDTMGTLFGLSSRANLLDEEDNLPEIEKPMLVDALSTIAASLFGTTTAGVYIESAAGIEQGGKTGFT
ALVVAALFALSLFFSPVLTIVPPFAYGPALVLVGMFMLHSVTKFNFSDYSELLPAFLTVALIIFTFNIGVGITAGFISYT
VLKLFTGRAGEVHPGMWILALLSFTFYLFYPYH

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=422, Percent_Identity=38.6255924170616, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1790150, Length=433, Percent_Identity=39.0300230946882, Blast_Score=298, Evalue=3e-82,
Organism=Escherichia coli, GI1790499, Length=436, Percent_Identity=34.4036697247706, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI48994909, Length=434, Percent_Identity=35.0230414746544, Blast_Score=232, Evalue=4e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46239; Mature: 46239

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSYFNFQEHRTSYRQEFLAGITTFFTLSYIIIVNPAILAAAGIPKGASMTATILTAIFG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TLLMGVYAKRPFAVAPYMGENAFIAYTVVQTLGYSWQTAMAAIFISGVLFTLITLAGLRG
HHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLAKAIPGSLKHSFSAGIGLFLAFLGLGNMGIVTLGVPGAPVQLGNIAQLPVLLSLGGLL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHH
VTAVLLIQRITGAILAGMVVTTAAFLLTSLIPLPQTLFSMPPSIEPIFMKIDIRGAWTWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEEECCCCHHH
FAGVITSVLVMDFVDTMGTLFGLSSRANLLDEEDNLPEIEKPMLVDALSTIAASLFGTTT
HHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
AGVYIESAAGIEQGGKTGFTALVVAALFALSLFFSPVLTIVPPFAYGPALVLVGMFMLHS
HCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VTKFNFSDYSELLPAFLTVALIIFTFNIGVGITAGFISYTVLKLFTGRAGEVHPGMWILA
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LLSFTFYLFYPYH
HHHHHHHHHCCCC
>Mature Secondary Structure
MQSYFNFQEHRTSYRQEFLAGITTFFTLSYIIIVNPAILAAAGIPKGASMTATILTAIFG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TLLMGVYAKRPFAVAPYMGENAFIAYTVVQTLGYSWQTAMAAIFISGVLFTLITLAGLRG
HHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLAKAIPGSLKHSFSAGIGLFLAFLGLGNMGIVTLGVPGAPVQLGNIAQLPVLLSLGGLL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHH
VTAVLLIQRITGAILAGMVVTTAAFLLTSLIPLPQTLFSMPPSIEPIFMKIDIRGAWTWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEEECCCCHHH
FAGVITSVLVMDFVDTMGTLFGLSSRANLLDEEDNLPEIEKPMLVDALSTIAASLFGTTT
HHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
AGVYIESAAGIEQGGKTGFTALVVAALFALSLFFSPVLTIVPPFAYGPALVLVGMFMLHS
HCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VTKFNFSDYSELLPAFLTVALIIFTFNIGVGITAGFISYTVLKLFTGRAGEVHPGMWILA
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LLSFTFYLFYPYH
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]