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The map label for this gene is lepB [H]

Identifier: 119357654

GI number: 119357654

Start: 2152553

End: 2153383

Strand: Reverse

Name: lepB [H]

Synonym: Cpha266_1858

Alternate gene names: 119357654

Gene position: 2153383-2152553 (Counterclockwise)

Preceding gene: 119357655

Following gene: 119357652

Centisome position: 68.71

GC content: 45.61

Gene sequence:

>831_bases
GTGAACAGTCAGCAGGGTAAATCCCCTAAAAAAAACTCAAGAGAATGGTTTGATGCGCTGATCATTGCAGCTATTTTTGC
AACTTTTTTAAGAGTTTTCGTTGTCGAATCCTACAGGATTCCCACCGGTTCCATGGAGAACACCCTGATGGCCGGTGATT
TTCTTTTTGTCAACAAATATGTATACGGCGCAAAGATACCCTTTACCGATTCGCGCCTGCCTGTTATTCAGCCGATTCAG
CGAGGAGATATTATCGTTTTCAAATTTCCCAAAGATCGTTCATTGAACTACATAAAGCGATGTGTGGCGCTTCCCGGCGA
TCTGCTTGAAATCAGGGATCGCAAGCTTTATGTGAACGGCAAGGAGTCCGCGCTGCCTGAGTATGCGCAGTTTCTTGGTG
AGCCCATGACGAAAGGAGTTGGTGATTTCCAGATATTCCCCCGTTTTTCACCTTTCAACAAGGATTATTACGGTCCGCTT
CAGATTCCCAAAAAAGGAGATGTTGTGGAACTTACTCCGCAAACCTATTCTTTATACAGCTCCCTGATTGCTGATGAAGG
CCATGATGTATCGCTGACCGGAAGCCTTGTTTTTGTTGACGGCAGTCCGGCATCAAGCTATACAGTCGAAAAAAACTACT
ACTTTGCGATGGGCGATAATCGCGATAACAGTCTTGACAGCCGTTTCTGGGGTTTTCTTCCTGAAACGGATATTGTCGGA
GAGGCAATGATGGTTTACTGGTCATGGGATCCGGATCTGCCGCTTTTGTTTGATCCTGTCAATAAACTGGGTTCTATTGC
ATGGCACCGTATTGGTCTCATGGTTCACTGA

Upstream 100 bases:

>100_bases
GCCAAAAGGCGACGGGTTGCAATAATTTGAGTCAAGCGCAGGTTACGGGAAAAAAAAACGTCAGAATCAACAACAGTAAA
TCATAAAACCACCGGATATC

Downstream 100 bases:

>100_bases
CGCTGTTTTGCCGCCTTCAGAATGCCGTTGTACAGCGTGCTGGTCGATGTTTTGATCATCCCGGGAGTGAAGAGTAGTTT
TTCGAGACCGGGACAGGTAA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MNSQQGKSPKKNSREWFDALIIAAIFATFLRVFVVESYRIPTGSMENTLMAGDFLFVNKYVYGAKIPFTDSRLPVIQPIQ
RGDIIVFKFPKDRSLNYIKRCVALPGDLLEIRDRKLYVNGKESALPEYAQFLGEPMTKGVGDFQIFPRFSPFNKDYYGPL
QIPKKGDVVELTPQTYSLYSSLIADEGHDVSLTGSLVFVDGSPASSYTVEKNYYFAMGDNRDNSLDSRFWGFLPETDIVG
EAMMVYWSWDPDLPLLFDPVNKLGSIAWHRIGLMVH

Sequences:

>Translated_276_residues
MNSQQGKSPKKNSREWFDALIIAAIFATFLRVFVVESYRIPTGSMENTLMAGDFLFVNKYVYGAKIPFTDSRLPVIQPIQ
RGDIIVFKFPKDRSLNYIKRCVALPGDLLEIRDRKLYVNGKESALPEYAQFLGEPMTKGVGDFQIFPRFSPFNKDYYGPL
QIPKKGDVVELTPQTYSLYSSLIADEGHDVSLTGSLVFVDGSPASSYTVEKNYYFAMGDNRDNSLDSRFWGFLPETDIVG
EAMMVYWSWDPDLPLLFDPVNKLGSIAWHRIGLMVH
>Mature_276_residues
MNSQQGKSPKKNSREWFDALIIAAIFATFLRVFVVESYRIPTGSMENTLMAGDFLFVNKYVYGAKIPFTDSRLPVIQPIQ
RGDIIVFKFPKDRSLNYIKRCVALPGDLLEIRDRKLYVNGKESALPEYAQFLGEPMTKGVGDFQIFPRFSPFNKDYYGPL
QIPKKGDVVELTPQTYSLYSSLIADEGHDVSLTGSLVFVDGSPASSYTVEKNYYFAMGDNRDNSLDSRFWGFLPETDIVG
EAMMVYWSWDPDLPLLFDPVNKLGSIAWHRIGLMVH

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=243, Percent_Identity=35.8024691358025, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533
- InterPro:   IPR019766 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 31363; Mature: 31363

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQQGKSPKKNSREWFDALIIAAIFATFLRVFVVESYRIPTGSMENTLMAGDFLFVNKY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEE
VYGAKIPFTDSRLPVIQPIQRGDIIVFKFPKDRSLNYIKRCVALPGDLLEIRDRKLYVNG
EEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHEEECCCEEEECC
KESALPEYAQFLGEPMTKGVGDFQIFPRFSPFNKDYYGPLQIPKKGDVVELTPQTYSLYS
CHHCCHHHHHHHCCHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHH
SLIADEGHDVSLTGSLVFVDGSPASSYTVEKNYYFAMGDNRDNSLDSRFWGFLPETDIVG
HHHHCCCCCEEEEEEEEEEECCCCCCEEEECCEEEEECCCCCCCCHHHHHCCCCCCCCCC
EAMMVYWSWDPDLPLLFDPVNKLGSIAWHRIGLMVH
CEEEEEEECCCCCCEEECCHHHHHHHHHHHEEEEEC
>Mature Secondary Structure
MNSQQGKSPKKNSREWFDALIIAAIFATFLRVFVVESYRIPTGSMENTLMAGDFLFVNKY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEE
VYGAKIPFTDSRLPVIQPIQRGDIIVFKFPKDRSLNYIKRCVALPGDLLEIRDRKLYVNG
EEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHEEECCCEEEECC
KESALPEYAQFLGEPMTKGVGDFQIFPRFSPFNKDYYGPLQIPKKGDVVELTPQTYSLYS
CHHCCHHHHHHHCCHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHH
SLIADEGHDVSLTGSLVFVDGSPASSYTVEKNYYFAMGDNRDNSLDSRFWGFLPETDIVG
HHHHCCCCCEEEEEEEEEEECCCCCCEEEECCEEEEECCCCCCCCHHHHHCCCCCCCCCC
EAMMVYWSWDPDLPLLFDPVNKLGSIAWHRIGLMVH
CEEEEEEECCCCCCEEECCHHHHHHHHHHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]