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The map label for this gene is aspS

Identifier: 119357451

GI number: 119357451

Start: 1877655

End: 1879475

Strand: Reverse

Name: aspS

Synonym: Cpha266_1650

Alternate gene names: 119357451

Gene position: 1879475-1877655 (Counterclockwise)

Preceding gene: 119357452

Following gene: 119357450

Centisome position: 59.97

GC content: 50.69

Gene sequence:

>1821_bases
ATGAGTAGAGCCGCAGGCAGCACGGAGACTCTGAAAAACCGGTTTCGTACCGATTATTGCGGGTTGTTGAACCCGGAAGT
TGAGCATCAGTCGGTAAAACTCGGCGGCTGGGTTCACCGAAAAAGAGATCATGGCGGGTTGATTTTTATTGATCTGAGAG
ATCATACCGGTATATGCCAGATTGTCATACAGCCAGAAGAACAGCAGTTGTTCGCCAAAGCCGAACAGCTTCATCTTGAA
TCGGTTATCTGTATAGAAGGGACTGTTGTACGCCGAAGTCCCGGCGCAGTCAACCCCCGTATTCCTTCCGGCGAAATCGA
GGTGGTTGCAGCAGGCATCAGTGTGGAAAGCAGTGCGCATCCGCTGCCGTTCCCTGTTGCCGATGAGGTGCAAACCTCCG
AAGAGCTTCGGCTGAAGTATCGTTTTATCGATTTGCGTCGGGATAAAATTCATGAAAACATAATTTTCCGCAGCAGGCTG
ACCGCAGCCATACGCCGGTATCTTGAAGAAAAGTCATTTATCGAGATACAGACACCTATTCTCACATCGAGTTCTCCTGA
AGGCGCCAGGGACTTTCTTGTACCAAGCCGACTGCACCCCGGGAAATTCTATGCGCTTCCCCAGGCTCCGCAGCAGTTCA
AGCAGCTTCTGATGGTATCGGGATTCCCGCGTTACTTTCAGATAGCCCCCTGCTTCAGGGACGAAGATGCCCGTGCCGAC
CGGAGTCCCGGCGAGTTTTATCAACTTGATATGGAGATGGCGTTTATAGAGCAGGATGACCTTTTTGAGATTCTTGAAGG
GATGTTCAGTCATCTTACCGGGAGCATGTCGACAAAGCGTATCCGGGAGTTTCCTTTTCCGCGCATCAGTTTCAGGGATG
TGATGAACCGGTACGGAACCGACAAGCCTGATCTGCGAATTCCTCTTGAAATCAGCGATGTCACCCATCTTTTTCTCCAA
TCCTCTTTCAAGGTGTTTGCCGCCAATACCAAAGAGGGGTGTTGTGTCAAGGCGATGCTCGTGAAAGGACGCGGTAACGA
GTCGAGGCTTTTTTATGATAAAGCTGAAAAACGCGCCAAAGAGCTTGGTTCAGGAGGGCTCGCATACATACAGTTCAGGG
AAGATGGCCCGAAAGGCCCTCTGGTGAAGTTTCTTTCAGGAGAGGAGCTTGCAGCCCTTCGCGAACTTCTTGGTGTCGAG
GTTGGCGATGTGGTGTTTTTCGGTGCCGGAAAGTGGGAACAGACCTGCAGGATTATGGGCGGCATGAGAACCTATTTCAG
CGATCTGTTTACTCTTGATCGTGATGAACTTGCATTCTGCTGGGTTGTTGATTTTCCCATGTACGAGTATAACGAGGATC
AGAAGAAGATTGATTTTTCACACAACCCGTTTTCCATGCCGCAGGGTGAGATGGATGCGCTTGAATCAATGCCTCCACTC
AATATTCTTGCCTACCAGTATGATATCGTGTGCAACGGCATTGAACTTTCAAGCGGCGCCATAAGAAACCACAGGCCGGA
TATCATGTACAAGGCGTTTGAGATTGCCGGTTACACAAAAGAGGATGTTGACAGCCGGTTCGGTCATATGATTGAAGCCT
TCAAGCTTGGAGCGCCACCTCACGGAGGCATCGCTCCCGGTCTCGACAGGCTGGTCATGATTCTGCGTGACGAGCAGAAT
ATTCGCGAGGTGATCGCATTTCCCATGAATCAGCAGGCGCAGGATCTCATGATGGGTTCTCCGTCAGAGGTCACTCCCAT
CCAATTACGGGAGCTGCATTTGCAGGTCGAGTTGCCGAAAAAGGCTGAGGCGAAACCGTAG

Upstream 100 bases:

>100_bases
ATTGAAGAGTCGGGATGGTTTTATAAATCATCAAAAATTCATCATATTCAGGATTTTCAAGGGAAAGTCATTTCAATATT
TCAAAGGAAGTTGGAGCGTT

Downstream 100 bases:

>100_bases
GGTGTAGAGGGAAATGTTCTGTATGGTATGAACACGGAGGGGAGAAAAATCCCTCTCCCTCCGTGTTTAATGTGGACGCC
CTGAAGCAGGAGATGCGGAT

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MSRAAGSTETLKNRFRTDYCGLLNPEVEHQSVKLGGWVHRKRDHGGLIFIDLRDHTGICQIVIQPEEQQLFAKAEQLHLE
SVICIEGTVVRRSPGAVNPRIPSGEIEVVAAGISVESSAHPLPFPVADEVQTSEELRLKYRFIDLRRDKIHENIIFRSRL
TAAIRRYLEEKSFIEIQTPILTSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVSGFPRYFQIAPCFRDEDARAD
RSPGEFYQLDMEMAFIEQDDLFEILEGMFSHLTGSMSTKRIREFPFPRISFRDVMNRYGTDKPDLRIPLEISDVTHLFLQ
SSFKVFAANTKEGCCVKAMLVKGRGNESRLFYDKAEKRAKELGSGGLAYIQFREDGPKGPLVKFLSGEELAALRELLGVE
VGDVVFFGAGKWEQTCRIMGGMRTYFSDLFTLDRDELAFCWVVDFPMYEYNEDQKKIDFSHNPFSMPQGEMDALESMPPL
NILAYQYDIVCNGIELSSGAIRNHRPDIMYKAFEIAGYTKEDVDSRFGHMIEAFKLGAPPHGGIAPGLDRLVMILRDEQN
IREVIAFPMNQQAQDLMMGSPSEVTPIQLRELHLQVELPKKAEAKP

Sequences:

>Translated_606_residues
MSRAAGSTETLKNRFRTDYCGLLNPEVEHQSVKLGGWVHRKRDHGGLIFIDLRDHTGICQIVIQPEEQQLFAKAEQLHLE
SVICIEGTVVRRSPGAVNPRIPSGEIEVVAAGISVESSAHPLPFPVADEVQTSEELRLKYRFIDLRRDKIHENIIFRSRL
TAAIRRYLEEKSFIEIQTPILTSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVSGFPRYFQIAPCFRDEDARAD
RSPGEFYQLDMEMAFIEQDDLFEILEGMFSHLTGSMSTKRIREFPFPRISFRDVMNRYGTDKPDLRIPLEISDVTHLFLQ
SSFKVFAANTKEGCCVKAMLVKGRGNESRLFYDKAEKRAKELGSGGLAYIQFREDGPKGPLVKFLSGEELAALRELLGVE
VGDVVFFGAGKWEQTCRIMGGMRTYFSDLFTLDRDELAFCWVVDFPMYEYNEDQKKIDFSHNPFSMPQGEMDALESMPPL
NILAYQYDIVCNGIELSSGAIRNHRPDIMYKAFEIAGYTKEDVDSRFGHMIEAFKLGAPPHGGIAPGLDRLVMILRDEQN
IREVIAFPMNQQAQDLMMGSPSEVTPIQLRELHLQVELPKKAEAKP
>Mature_605_residues
SRAAGSTETLKNRFRTDYCGLLNPEVEHQSVKLGGWVHRKRDHGGLIFIDLRDHTGICQIVIQPEEQQLFAKAEQLHLES
VICIEGTVVRRSPGAVNPRIPSGEIEVVAAGISVESSAHPLPFPVADEVQTSEELRLKYRFIDLRRDKIHENIIFRSRLT
AAIRRYLEEKSFIEIQTPILTSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVSGFPRYFQIAPCFRDEDARADR
SPGEFYQLDMEMAFIEQDDLFEILEGMFSHLTGSMSTKRIREFPFPRISFRDVMNRYGTDKPDLRIPLEISDVTHLFLQS
SFKVFAANTKEGCCVKAMLVKGRGNESRLFYDKAEKRAKELGSGGLAYIQFREDGPKGPLVKFLSGEELAALRELLGVEV
GDVVFFGAGKWEQTCRIMGGMRTYFSDLFTLDRDELAFCWVVDFPMYEYNEDQKKIDFSHNPFSMPQGEMDALESMPPLN
ILAYQYDIVCNGIELSSGAIRNHRPDIMYKAFEIAGYTKEDVDSRFGHMIEAFKLGAPPHGGIAPGLDRLVMILRDEQNI
REVIAFPMNQQAQDLMMGSPSEVTPIQLRELHLQVELPKKAEAKP

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=603, Percent_Identity=35.3233830845771, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI45439306, Length=282, Percent_Identity=29.4326241134752, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI5031815, Length=261, Percent_Identity=29.8850574712644, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI194272210, Length=261, Percent_Identity=29.8850574712644, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI226491502, Length=259, Percent_Identity=23.5521235521236, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI1788173, Length=597, Percent_Identity=42.0435510887772, Blast_Score=453, Evalue=1e-128,
Organism=Escherichia coli, GI1790571, Length=301, Percent_Identity=26.578073089701, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1789256, Length=312, Percent_Identity=24.0384615384615, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787161, Length=278, Percent_Identity=24.8201438848921, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566633, Length=607, Percent_Identity=32.2899505766063, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17551876, Length=279, Percent_Identity=26.1648745519713, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71994340, Length=279, Percent_Identity=25.8064516129032, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535925, Length=279, Percent_Identity=25.8064516129032, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17535927, Length=279, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325153, Length=307, Percent_Identity=36.4820846905537, Blast_Score=157, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6323011, Length=282, Percent_Identity=29.4326241134752, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321807, Length=252, Percent_Identity=27.3809523809524, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320242, Length=264, Percent_Identity=26.5151515151515, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584738, Length=605, Percent_Identity=33.3884297520661, Blast_Score=313, Evalue=3e-85,
Organism=Drosophila melanogaster, GI17136276, Length=253, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19921528, Length=234, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640849, Length=262, Percent_Identity=26.3358778625954, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640851, Length=262, Percent_Identity=26.3358778625954, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_CHLPD (A1BGZ4)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912095.1
- ProteinModelPortal:   A1BGZ4
- SMR:   A1BGZ4
- STRING:   A1BGZ4
- GeneID:   4571030
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_1650
- NMPDR:   fig|290317.7.peg.1731
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   YQLDVEM
- ProtClustDB:   PRK00476
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 68833; Mature: 68702

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAAGSTETLKNRFRTDYCGLLNPEVEHQSVKLGGWVHRKRDHGGLIFIDLRDHTGICQ
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCEEEEECCCCCEEEEEECCCCCEEE
IVIQPEEQQLFAKAEQLHLESVICIEGTVVRRSPGAVNPRIPSGEIEVVAAGISVESSAH
EEECCCHHHHHHHHHHHHHHEEEEECCEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCC
PLPFPVADEVQTSEELRLKYRFIDLRRDKIHENIIFRSRLTAAIRRYLEEKSFIEIQTPI
CCCCCCCHHHCCCHHHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCE
LTSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVSGFPRYFQIAPCFRDEDARAD
EECCCCCCCHHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
RSPGEFYQLDMEMAFIEQDDLFEILEGMFSHLTGSMSTKRIREFPFPRISFRDVMNRYGT
CCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHCC
DKPDLRIPLEISDVTHLFLQSSFKVFAANTKEGCCVKAMLVKGRGNESRLFYDKAEKRAK
CCCCEEEEEEHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCEEEHHHHHHHHH
ELGSGGLAYIQFREDGPKGPLVKFLSGEELAALRELLGVEVGDVVFFGAGKWEQTCRIMG
HHCCCCEEEEEEECCCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
GMRTYFSDLFTLDRDELAFCWVVDFPMYEYNEDQKKIDFSHNPFSMPQGEMDALESMPPL
HHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHHHHHCCCCC
NILAYQYDIVCNGIELSSGAIRNHRPDIMYKAFEIAGYTKEDVDSRFGHMIEAFKLGAPP
EEEEEEEEEEECCEEECCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCC
HGGIAPGLDRLVMILRDEQNIREVIAFPMNQQAQDLMMGSPSEVTPIQLRELHLQVELPK
CCCCCCCHHHHEEECCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEEEEEEEEEECCC
KAEAKP
CCCCCC
>Mature Secondary Structure 
SRAAGSTETLKNRFRTDYCGLLNPEVEHQSVKLGGWVHRKRDHGGLIFIDLRDHTGICQ
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCEEEEECCCCCEEEEEECCCCCEEE
IVIQPEEQQLFAKAEQLHLESVICIEGTVVRRSPGAVNPRIPSGEIEVVAAGISVESSAH
EEECCCHHHHHHHHHHHHHHEEEEECCEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCC
PLPFPVADEVQTSEELRLKYRFIDLRRDKIHENIIFRSRLTAAIRRYLEEKSFIEIQTPI
CCCCCCCHHHCCCHHHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCE
LTSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVSGFPRYFQIAPCFRDEDARAD
EECCCCCCCHHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
RSPGEFYQLDMEMAFIEQDDLFEILEGMFSHLTGSMSTKRIREFPFPRISFRDVMNRYGT
CCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHCC
DKPDLRIPLEISDVTHLFLQSSFKVFAANTKEGCCVKAMLVKGRGNESRLFYDKAEKRAK
CCCCEEEEEEHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCEEEHHHHHHHHH
ELGSGGLAYIQFREDGPKGPLVKFLSGEELAALRELLGVEVGDVVFFGAGKWEQTCRIMG
HHCCCCEEEEEEECCCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
GMRTYFSDLFTLDRDELAFCWVVDFPMYEYNEDQKKIDFSHNPFSMPQGEMDALESMPPL
HHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHHHHHCCCCC
NILAYQYDIVCNGIELSSGAIRNHRPDIMYKAFEIAGYTKEDVDSRFGHMIEAFKLGAPP
EEEEEEEEEEECCEEECCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCC
HGGIAPGLDRLVMILRDEQNIREVIAFPMNQQAQDLMMGSPSEVTPIQLRELHLQVELPK
CCCCCCCHHHHEEECCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEEEEEEEEEECCC
KAEAKP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA