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The map label for this gene is 119357395

Identifier: 119357395

GI number: 119357395

Start: 1807279

End: 1808721

Strand: Reverse

Name: 119357395

Synonym: Cpha266_1594

Alternate gene names: NA

Gene position: 1808721-1807279 (Counterclockwise)

Preceding gene: 119357397

Following gene: 119357394

Centisome position: 57.71

GC content: 53.5

Gene sequence:

>1443_bases
ATGGCCACCCGACTGGGTATCGACGACATGATTGGAGCATGTGCTGATCTTGACGAAGCAGGTTTCTGGTCGATCGAGTG
CTGGGGCGGAGCTACCTACGACGCCTGCATTCGCTATCTGAACGAAGATCCCTGGGATAGACTGCGCACGTTCAAGAGTC
TGATGCCAAAAACTCCGCTGCAGATGCTCTTGCGCGGTCAGAATCTTTTGGGATATCGCCACTATGAGGATGAGGTTGTG
CAGCGTTTCTGTCAGAAGTCTGTGGAAAACGGTATTGACATTTTCCGGATTTTCGATGCCCTCAATGACCTCAGAAACAT
CGAAACCTCTGTCCGGGCGGTCAGGACGGCTGGTGGACACGCTCAGGGCACGATATCCTATACAGTCAGCCCGATCCACA
CCACCGAAATGTTTGTCGATCAGGCTCGAAGGCTTCAGGATATGGGTATTGACTCAATCTGTATCAAGGATATGGCTGCA
CTTATCAAGCCCCAGGCGGCATTTGATCTGGTCAAGGGGATTAAGGATGCGTGCGGCAAGGAGTTGCGTGTGCACTTGCA
TGCGCATGCAACGACCGGTGTCACCCTTGTGAGTCTCATGAAGGCTGTCGAGGCAGGGGTTGATTGCGTGGACACCGCCA
TCAGCTCCATGAGTCTCGGGCCGGGGCACAATCCTACGGAGAGTTTTGTTGAGATGCTTGAAGGAACAGGTTATACTACA
AAGGTCAATCAGGAAAAAATTCTGCGGGTCAAGGAGCATTTCTCGGAAGTGCTGGGGAGATACAGCGAGTACCAGTCGAA
GGTTATCGGAGTGGATACGGAGATTTTCAGAAGCCAGATCCCTGGCGGAATGCTCTCAAACATGGAGAACCAGCTCAGGC
AGCAGGGCGGCGGCGATCGTATTAAGGAGGTGCTGGAGGAGATTCCTCTGGTTCGCAAAGATACCGGTTACGTGCCTCTC
GTAACCCCTACCAGCCAGATTGTCGGCACCCAGGCAGTGCTGAATGTTCTAATGGGAAGATATGCAGTGCTGACGGGCGA
ATTCGCCGATCTCATGCTTGGCTACTATGGAGAAGTGCCGGGAGAGAAAAATCCTGAGGTAGTTGAATTTGCGCGCGCCC
ATGCAGCAAAAGAACCCATAACCTGCAGGCCGGCTGATCTCATGAAACCGGAGTGGCAGAAACTTCGTTCGGCAGCTCTG
GCTCTCAGCGGCTGCAACGGTACGGACGAGGATGTTCTTACCTACAGCATGTTTCCACAGGTGGCCCCGAAATATTTTGC
AGAACGTCACGAAGGTCCTCGTAATCTGGGTAAGGATCCTCTTACCGGTGCTTCCGAAACGCACCCGCCCGAAGGACATC
AGGGCATCATAACCGGCCCCATCACCTACTCAGTGACCATGAGTGGTCGGCAGCATAAGGTGACGGTAGCGCCATACCAG
TAA

Upstream 100 bases:

>100_bases
TCGGAACATATCGTATTGCCAACTTTAAGAGTCTGGAGTTATCATTAATAGAATTATAGATATTACCGAGCTTACCCTGC
GGGACGCCCATCAGAGCCTT

Downstream 100 bases:

>100_bases
ACACAGGCGAACAAACATGAATATTGACCAGAAAATACAGGAGCTGAACCAGCGTAAAGATGAAATACAGCTCGGTGGGG
GAGTGGCGCGGATTGAGAAG

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: Transcarboxylase 5S subunit [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MATRLGIDDMIGACADLDEAGFWSIECWGGATYDACIRYLNEDPWDRLRTFKSLMPKTPLQMLLRGQNLLGYRHYEDEVV
QRFCQKSVENGIDIFRIFDALNDLRNIETSVRAVRTAGGHAQGTISYTVSPIHTTEMFVDQARRLQDMGIDSICIKDMAA
LIKPQAAFDLVKGIKDACGKELRVHLHAHATTGVTLVSLMKAVEAGVDCVDTAISSMSLGPGHNPTESFVEMLEGTGYTT
KVNQEKILRVKEHFSEVLGRYSEYQSKVIGVDTEIFRSQIPGGMLSNMENQLRQQGGGDRIKEVLEEIPLVRKDTGYVPL
VTPTSQIVGTQAVLNVLMGRYAVLTGEFADLMLGYYGEVPGEKNPEVVEFARAHAAKEPITCRPADLMKPEWQKLRSAAL
ALSGCNGTDEDVLTYSMFPQVAPKYFAERHEGPRNLGKDPLTGASETHPPEGHQGIITGPITYSVTMSGRQHKVTVAPYQ

Sequences:

>Translated_480_residues
MATRLGIDDMIGACADLDEAGFWSIECWGGATYDACIRYLNEDPWDRLRTFKSLMPKTPLQMLLRGQNLLGYRHYEDEVV
QRFCQKSVENGIDIFRIFDALNDLRNIETSVRAVRTAGGHAQGTISYTVSPIHTTEMFVDQARRLQDMGIDSICIKDMAA
LIKPQAAFDLVKGIKDACGKELRVHLHAHATTGVTLVSLMKAVEAGVDCVDTAISSMSLGPGHNPTESFVEMLEGTGYTT
KVNQEKILRVKEHFSEVLGRYSEYQSKVIGVDTEIFRSQIPGGMLSNMENQLRQQGGGDRIKEVLEEIPLVRKDTGYVPL
VTPTSQIVGTQAVLNVLMGRYAVLTGEFADLMLGYYGEVPGEKNPEVVEFARAHAAKEPITCRPADLMKPEWQKLRSAAL
ALSGCNGTDEDVLTYSMFPQVAPKYFAERHEGPRNLGKDPLTGASETHPPEGHQGIITGPITYSVTMSGRQHKVTVAPYQ
>Mature_479_residues
ATRLGIDDMIGACADLDEAGFWSIECWGGATYDACIRYLNEDPWDRLRTFKSLMPKTPLQMLLRGQNLLGYRHYEDEVVQ
RFCQKSVENGIDIFRIFDALNDLRNIETSVRAVRTAGGHAQGTISYTVSPIHTTEMFVDQARRLQDMGIDSICIKDMAAL
IKPQAAFDLVKGIKDACGKELRVHLHAHATTGVTLVSLMKAVEAGVDCVDTAISSMSLGPGHNPTESFVEMLEGTGYTTK
VNQEKILRVKEHFSEVLGRYSEYQSKVIGVDTEIFRSQIPGGMLSNMENQLRQQGGGDRIKEVLEEIPLVRKDTGYVPLV
TPTSQIVGTQAVLNVLMGRYAVLTGEFADLMLGYYGEVPGEKNPEVVEFARAHAAKEPITCRPADLMKPEWQKLRSAALA
LSGCNGTDEDVLTYSMFPQVAPKYFAERHEGPRNLGKDPLTGASETHPPEGHQGIITGPITYSVTMSGRQHKVTVAPYQ

Specific function: The 5S subunit specifically catalyzes the transfer of the carboxyl group from biotin of the 1.3S subunit to pyruvate to form oxaloacetate and 1.3S biotin [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=444, Percent_Identity=32.6576576576577, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI106049295, Length=444, Percent_Identity=32.6576576576577, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI106049292, Length=444, Percent_Identity=32.6576576576577, Blast_Score=219, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17562816, Length=459, Percent_Identity=31.3725490196078, Blast_Score=220, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6319695, Length=439, Percent_Identity=32.8018223234624, Blast_Score=232, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6321376, Length=439, Percent_Identity=33.0296127562642, Blast_Score=231, Evalue=1e-61,
Organism=Drosophila melanogaster, GI281363050, Length=453, Percent_Identity=30.9050772626932, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24652224, Length=453, Percent_Identity=30.9050772626932, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24652222, Length=453, Percent_Identity=30.9050772626932, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24652220, Length=453, Percent_Identity=30.9050772626932, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24652218, Length=453, Percent_Identity=30.9050772626932, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24652212, Length=453, Percent_Identity=30.9050772626932, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24652210, Length=453, Percent_Identity=30.9050772626932, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24652214, Length=453, Percent_Identity=30.9050772626932, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI19921944, Length=453, Percent_Identity=30.9050772626932, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24652216, Length=453, Percent_Identity=30.9050772626932, Blast_Score=206, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR003379
- InterPro:   IPR000891 [H]

Pfam domain/function: PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =2.1.3.1 [H]

Molecular weight: Translated: 53004; Mature: 52873

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50991 PYR_CT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRLGIDDMIGACADLDEAGFWSIECWGGATYDACIRYLNEDPWDRLRTFKSLMPKTPL
CCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHH
QMLLRGQNLLGYRHYEDEVVQRFCQKSVENGIDIFRIFDALNDLRNIETSVRAVRTAGGH
HHHHCCCHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AQGTISYTVSPIHTTEMFVDQARRLQDMGIDSICIKDMAALIKPQAAFDLVKGIKDACGK
CCEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
ELRVHLHAHATTGVTLVSLMKAVEAGVDCVDTAISSMSLGPGHNPTESFVEMLEGTGYTT
EEEEEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEE
KVNQEKILRVKEHFSEVLGRYSEYQSKVIGVDTEIFRSQIPGGMLSNMENQLRQQGGGDR
ECCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHCCCHHHHHHHHHHHHCCCCHH
IKEVLEEIPLVRKDTGYVPLVTPTSQIVGTQAVLNVLMGRYAVLTGEFADLMLGYYGEVP
HHHHHHHCCCEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GEKNPEVVEFARAHAAKEPITCRPADLMKPEWQKLRSAALALSGCNGTDEDVLTYSMFPQ
CCCCCHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCHHEEHHHHHH
VAPKYFAERHEGPRNLGKDPLTGASETHPPEGHQGIITGPITYSVTMSGRQHKVTVAPYQ
HHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEECCCCEEEEECCCC
>Mature Secondary Structure 
ATRLGIDDMIGACADLDEAGFWSIECWGGATYDACIRYLNEDPWDRLRTFKSLMPKTPL
CCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHH
QMLLRGQNLLGYRHYEDEVVQRFCQKSVENGIDIFRIFDALNDLRNIETSVRAVRTAGGH
HHHHCCCHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AQGTISYTVSPIHTTEMFVDQARRLQDMGIDSICIKDMAALIKPQAAFDLVKGIKDACGK
CCEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
ELRVHLHAHATTGVTLVSLMKAVEAGVDCVDTAISSMSLGPGHNPTESFVEMLEGTGYTT
EEEEEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEE
KVNQEKILRVKEHFSEVLGRYSEYQSKVIGVDTEIFRSQIPGGMLSNMENQLRQQGGGDR
ECCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHCCCHHHHHHHHHHHHCCCCHH
IKEVLEEIPLVRKDTGYVPLVTPTSQIVGTQAVLNVLMGRYAVLTGEFADLMLGYYGEVP
HHHHHHHCCCEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GEKNPEVVEFARAHAAKEPITCRPADLMKPEWQKLRSAALALSGCNGTDEDVLTYSMFPQ
CCCCCHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCHHEEHHHHHH
VAPKYFAERHEGPRNLGKDPLTGASETHPPEGHQGIITGPITYSVTMSGRQHKVTVAPYQ
HHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEECCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8365490 [H]