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The map label for this gene is sbcD [H]

Identifier: 119357180

GI number: 119357180

Start: 1566453

End: 1567703

Strand: Reverse

Name: sbcD [H]

Synonym: Cpha266_1371

Alternate gene names: 119357180

Gene position: 1567703-1566453 (Counterclockwise)

Preceding gene: 119357181

Following gene: 119357174

Centisome position: 50.02

GC content: 54.28

Gene sequence:

>1251_bases
ATGAAATGTCTTCATACTTCCGACTGGCATTTAGGCCGAACTCTTTATGGCAGGAGCCGATACAGCGAGTTTTCAGCTTT
TCTCGACTGGCTTTCAGCTCTCATTGAAAAGGAAAAGGTCGATCTGCTTCTCGTGGCCGGAGATGTGTTCGATACCACGG
TGCCGGGTAGTCGGGCTCAGGAGCTCTACTATGGATTTCTCAACAAGGTTGCCCGATCGACGGTTTGCCGGCATGTGGTG
ATCACCTCCGGTAACCACGATTCTCCGTCGCTTCTCGATGCTCCGAAAGCTCTTCTGCGTACGCTCGATGTGCATGTGGC
AGGCTCGGTGACCGACGATCCGATGAACGACGAAGTACTGGTGCTTCGAGACAAAACCGGAAAGGCTGAAGCTGTCGTGT
GCGCCGTGCCGCATCTGCGTGATCGCGATATCCGTAGTGTGGGGCCGGGCGAAAGCATGCAAGACAAAAGTCTCAAGCTA
CTCGAAGGCATTGAGCGCCATTACCGCGAAGTGTGCAGGGCAGGGGAGGAACGGCGGGTTCAGGAGGGAGGGCGTATTCC
CATGATCGTCATGGGCCATCTGTTTACGGCCGGAGGTCAAACCATTGATAACGACGGTGTTCGCGAAATCTATGCGGGCT
CCCTTGCCCATGTGAGCCGTTCGATTTTTCCTCCGGGAATAGACTATCTTGCGCTCGGCCATCTGCATGTTCCGCAGATT
GTAGGAGGCGAAGAGCATCTGCGTTACAGCGGATCGCCAATACCTATGGGGTTTGGCGAGGCCAGCCAGCAGAAAATGGT
TGTGCTTGTTGAATTTACGGAGGGCGAACGGCTGATCACCGAAATTCCGATACCCTGTTTTCAGCCGCTCGAACGCATCA
GCGGTACGCTGCAGGCCATAACTGACCGCATTTTCGAATTGAAGGCTGCAGGCAGCAAGGCCTGGCTGGAGATCGAGTAT
ACCGGCGACGATCTTTCCGGAGACCTGAGAGGTCTGCTTGACAATGCCGTGAAAGGGTCACTGCTTGAAATCCGCAGAAT
CAAGAACAACCGGATTGTCGCTCTTGCCCTCAAGCAGCTATCGGAAGACGAATCGCTCGATGAACTCGGAGAACTCGACG
TCTTTAATCGTTGCCTCGATGCGGCAAAGGTTCCGCAGACTCAGCGCCCGGAGCTTCTTCAGGCCTATCAGGAGATTCTG
GTTTCGCTGCATGAAGATGAGAAGAAGATCAAGAGTGAGCCAAGGGAGTAA

Upstream 100 bases:

>100_bases
CTTGGGGGATTAGGAAAATCTTCCGGTACCGACACCTGAGGTTTTCTATGATGCTCTCCATCCCGGACTTTTTATGACGT
TGTGAAACGAAGTTAAACAT

Downstream 100 bases:

>100_bases
TTCCAATTCAACTTCATTAATGCACTCGTGATTCAAGGCTATGCGACGATGGATTAAAAATCTTGAAAATTAAAAAGATT
TGCCTGCGAATTTTCACTGA

Product: exodeoxyribonuclease I subunit D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MKCLHTSDWHLGRTLYGRSRYSEFSAFLDWLSALIEKEKVDLLLVAGDVFDTTVPGSRAQELYYGFLNKVARSTVCRHVV
ITSGNHDSPSLLDAPKALLRTLDVHVAGSVTDDPMNDEVLVLRDKTGKAEAVVCAVPHLRDRDIRSVGPGESMQDKSLKL
LEGIERHYREVCRAGEERRVQEGGRIPMIVMGHLFTAGGQTIDNDGVREIYAGSLAHVSRSIFPPGIDYLALGHLHVPQI
VGGEEHLRYSGSPIPMGFGEASQQKMVVLVEFTEGERLITEIPIPCFQPLERISGTLQAITDRIFELKAAGSKAWLEIEY
TGDDLSGDLRGLLDNAVKGSLLEIRRIKNNRIVALALKQLSEDESLDELGELDVFNRCLDAAKVPQTQRPELLQAYQEIL
VSLHEDEKKIKSEPRE

Sequences:

>Translated_416_residues
MKCLHTSDWHLGRTLYGRSRYSEFSAFLDWLSALIEKEKVDLLLVAGDVFDTTVPGSRAQELYYGFLNKVARSTVCRHVV
ITSGNHDSPSLLDAPKALLRTLDVHVAGSVTDDPMNDEVLVLRDKTGKAEAVVCAVPHLRDRDIRSVGPGESMQDKSLKL
LEGIERHYREVCRAGEERRVQEGGRIPMIVMGHLFTAGGQTIDNDGVREIYAGSLAHVSRSIFPPGIDYLALGHLHVPQI
VGGEEHLRYSGSPIPMGFGEASQQKMVVLVEFTEGERLITEIPIPCFQPLERISGTLQAITDRIFELKAAGSKAWLEIEY
TGDDLSGDLRGLLDNAVKGSLLEIRRIKNNRIVALALKQLSEDESLDELGELDVFNRCLDAAKVPQTQRPELLQAYQEIL
VSLHEDEKKIKSEPRE
>Mature_416_residues
MKCLHTSDWHLGRTLYGRSRYSEFSAFLDWLSALIEKEKVDLLLVAGDVFDTTVPGSRAQELYYGFLNKVARSTVCRHVV
ITSGNHDSPSLLDAPKALLRTLDVHVAGSVTDDPMNDEVLVLRDKTGKAEAVVCAVPHLRDRDIRSVGPGESMQDKSLKL
LEGIERHYREVCRAGEERRVQEGGRIPMIVMGHLFTAGGQTIDNDGVREIYAGSLAHVSRSIFPPGIDYLALGHLHVPQI
VGGEEHLRYSGSPIPMGFGEASQQKMVVLVEFTEGERLITEIPIPCFQPLERISGTLQAITDRIFELKAAGSKAWLEIEY
TGDDLSGDLRGLLDNAVKGSLLEIRRIKNNRIVALALKQLSEDESLDELGELDVFNRCLDAAKVPQTQRPELLQAYQEIL
VSLHEDEKKIKSEPRE

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sbcD family [H]

Homologues:

Organism=Escherichia coli, GI1786598, Length=413, Percent_Identity=36.5617433414044, Blast_Score=238, Evalue=5e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 46269; Mature: 46269

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCLHTSDWHLGRTLYGRSRYSEFSAFLDWLSALIEKEKVDLLLVAGDVFDTTVPGSRAQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCHHHH
ELYYGFLNKVARSTVCRHVVITSGNHDSPSLLDAPKALLRTLDVHVAGSVTDDPMNDEVL
HHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCEE
VLRDKTGKAEAVVCAVPHLRDRDIRSVGPGESMQDKSLKLLEGIERHYREVCRAGEERRV
EEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
QEGGRIPMIVMGHLFTAGGQTIDNDGVREIYAGSLAHVSRSIFPPGIDYLALGHLHVPQI
HCCCCCCEEEEEHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCHH
VGGEEHLRYSGSPIPMGFGEASQQKMVVLVEFTEGERLITEIPIPCFQPLERISGTLQAI
CCCHHHHEECCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHH
TDRIFELKAAGSKAWLEIEYTGDDLSGDLRGLLDNAVKGSLLEIRRIKNNRIVALALKQL
HHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEHHHC
SEDESLDELGELDVFNRCLDAAKVPQTQRPELLQAYQEILVSLHEDEKKIKSEPRE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKCLHTSDWHLGRTLYGRSRYSEFSAFLDWLSALIEKEKVDLLLVAGDVFDTTVPGSRAQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCHHHH
ELYYGFLNKVARSTVCRHVVITSGNHDSPSLLDAPKALLRTLDVHVAGSVTDDPMNDEVL
HHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCEE
VLRDKTGKAEAVVCAVPHLRDRDIRSVGPGESMQDKSLKLLEGIERHYREVCRAGEERRV
EEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
QEGGRIPMIVMGHLFTAGGQTIDNDGVREIYAGSLAHVSRSIFPPGIDYLALGHLHVPQI
HCCCCCCEEEEEHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCHH
VGGEEHLRYSGSPIPMGFGEASQQKMVVLVEFTEGERLITEIPIPCFQPLERISGTLQAI
CCCHHHHEECCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHH
TDRIFELKAAGSKAWLEIEYTGDDLSGDLRGLLDNAVKGSLLEIRRIKNNRIVALALKQL
HHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEHHHC
SEDESLDELGELDVFNRCLDAAKVPQTQRPELLQAYQEILVSLHEDEKKIKSEPRE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]