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The map label for this gene is arlR [H]

Identifier: 119357020

GI number: 119357020

Start: 1372996

End: 1373664

Strand: Reverse

Name: arlR [H]

Synonym: Cpha266_1205

Alternate gene names: 119357020

Gene position: 1373664-1372996 (Counterclockwise)

Preceding gene: 119357021

Following gene: 119357019

Centisome position: 43.83

GC content: 49.33

Gene sequence:

>669_bases
ATGCGGATTCTTGTTATCGAAGACGAACCGGGAATATCCGGATTTCTCAAGGAGGGACTGGAAGAGGAGTATTTTGCCGT
CGATCTTGCTTTCGACGGCAAAACCGGGCTTGACATGGCGATCCTGAACGAATATGATCTCATGATCGTTGACTGGATGA
TTCCCGGAATCAGCGGCATAGAGGTATGCCGACAGGTACGCAAAGCCGGAAGTTCCGTTCCGATCATCTTTTTGACCGCA
AAAGACACCCTTGAGGATATCGTGTTCGGTCTCGATGCAGGAGCAAACGATTATATCAGAAAACCTTTCGCATTCGAGGA
GCTGCTGGCCCGCATACGGGTGCAGCTTCGCCGAAACAATCCGGAAAGCGACGCCATAACGGCTGGATTCGTGACCGTAA
ACCCGGTTACCCACCAGGTATTCTGCAGGGATACAGAAATCGCACTGACCCCCAAGGAATTTTCCCTGCTTGAATTTCTG
GCACGCAACAAGGATAAAGTCTGCACAAGAAGCCGGATCATCGAACATGTCCGGGATATGCATTTCGACTCCGATACATC
GATCATCGATGTCTATATCAATTTCCTTCGAAAGAAACTCGACTGTTCAGGATGCGGAAACATCATTCAAACGATTCGGG
GCGTCGGCTACATTATTCGTGAATCCTGA

Upstream 100 bases:

>100_bases
AGGAGCTTGCCGTGCTCGGCTCGTTGCTCGAAAATTCCGTAAAAGGCGGACAGCGTGACAGTGATGATAATGACGACAAA
CATTAACGGACTATTTGGCC

Downstream 100 bases:

>100_bases
ATACCGGTCATAAAAAAACATACCTGGTTGACCGGAGAGCCTTTACGTTCCGTACCGGAAAAATTTTCCCTGAGTTTACG
TAATCGCATTGCTCTCTACT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MRILVIEDEPGISGFLKEGLEEEYFAVDLAFDGKTGLDMAILNEYDLMIVDWMIPGISGIEVCRQVRKAGSSVPIIFLTA
KDTLEDIVFGLDAGANDYIRKPFAFEELLARIRVQLRRNNPESDAITAGFVTVNPVTHQVFCRDTEIALTPKEFSLLEFL
ARNKDKVCTRSRIIEHVRDMHFDSDTSIIDVYINFLRKKLDCSGCGNIIQTIRGVGYIIRES

Sequences:

>Translated_222_residues
MRILVIEDEPGISGFLKEGLEEEYFAVDLAFDGKTGLDMAILNEYDLMIVDWMIPGISGIEVCRQVRKAGSSVPIIFLTA
KDTLEDIVFGLDAGANDYIRKPFAFEELLARIRVQLRRNNPESDAITAGFVTVNPVTHQVFCRDTEIALTPKEFSLLEFL
ARNKDKVCTRSRIIEHVRDMHFDSDTSIIDVYINFLRKKLDCSGCGNIIQTIRGVGYIIRES
>Mature_222_residues
MRILVIEDEPGISGFLKEGLEEEYFAVDLAFDGKTGLDMAILNEYDLMIVDWMIPGISGIEVCRQVRKAGSSVPIIFLTA
KDTLEDIVFGLDAGANDYIRKPFAFEELLARIRVQLRRNNPESDAITAGFVTVNPVTHQVFCRDTEIALTPKEFSLLEFL
ARNKDKVCTRSRIIEHVRDMHFDSDTSIIDVYINFLRKKLDCSGCGNIIQTIRGVGYIIRES

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=45.4954954954955, Blast_Score=183, Evalue=9e-48,
Organism=Escherichia coli, GI87082012, Length=217, Percent_Identity=40.5529953917051, Blast_Score=169, Evalue=9e-44,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=35.5855855855856, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=35.4260089686099, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=36.7713004484305, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=32.7272727272727, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=32.3008849557522, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=33.1818181818182, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.9366515837104, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=35.4545454545455, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.8947368421053, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=30.7359307359307, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=28.695652173913, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=28.5087719298246, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788550, Length=160, Percent_Identity=27.5, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=162, Percent_Identity=28.3950617283951, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25084; Mature: 25084

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVIEDEPGISGFLKEGLEEEYFAVDLAFDGKTGLDMAILNEYDLMIVDWMIPGISGI
CEEEEEECCCCCHHHHHCCCCCCEEEEEEEECCCCCCCEEEECCCCEEEEEECCCCCCHH
EVCRQVRKAGSSVPIIFLTAKDTLEDIVFGLDAGANDYIRKPFAFEELLARIRVQLRRNN
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHCCC
PESDAITAGFVTVNPVTHQVFCRDTEIALTPKEFSLLEFLARNKDKVCTRSRIIEHVRDM
CCCCCEEEEEEEECCCEEEEEECCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
HFDSDTSIIDVYINFLRKKLDCSGCGNIIQTIRGVGYIIRES
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MRILVIEDEPGISGFLKEGLEEEYFAVDLAFDGKTGLDMAILNEYDLMIVDWMIPGISGI
CEEEEEECCCCCHHHHHCCCCCCEEEEEEEECCCCCCCEEEECCCCEEEEEECCCCCCHH
EVCRQVRKAGSSVPIIFLTAKDTLEDIVFGLDAGANDYIRKPFAFEELLARIRVQLRRNN
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHCCC
PESDAITAGFVTVNPVTHQVFCRDTEIALTPKEFSLLEFLARNKDKVCTRSRIIEHVRDM
CCCCCEEEEEEEECCCEEEEEECCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
HFDSDTSIIDVYINFLRKKLDCSGCGNIIQTIRGVGYIIRES
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA