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The map label for this gene is coaD

Identifier: 119356842

GI number: 119356842

Start: 1155897

End: 1156400

Strand: Reverse

Name: coaD

Synonym: Cpha266_1015

Alternate gene names: 119356842

Gene position: 1156400-1155897 (Counterclockwise)

Preceding gene: 119356843

Following gene: 119356841

Centisome position: 36.9

GC content: 44.05

Gene sequence:

>504_bases
ATGAAACGCAAAGCCATTTATCCGGGAACATTTGATCCGTTTACCAACGGTCACCTTGACGTTCTGGATCGTGCACTGAA
TATCTTTGATGAAGTTGAAGTGGTTATTGGCGAAAACAGTCAAAAAAAAACACTCTTTACGGTTAATGAACGACTTGAAA
TGATCAGGGAAATTGTCATCGAGTTTCCCGGAGTAACCGTTGCGGTTCTGCATGACGGGCTTCTTGCCAATTATGCCCGA
CAGGTCGAAGCAAGAGCTATTGTTCGGGGGGTTCGACAGGTCAAGGATTTCGAGTACGAATTTCAGATGTCTCTGTTGAA
CCGCCATCTCTATCCGGAAGTGACCACGGTTTTTCTTATGCCTAATGTCAAGTATACCTATGTTGCATCATCGATCATCA
GAGAGGTTGCCATGCTTGGCGGTGACGTAAGCAAATTTGTACACCCCTGCGTTCTGGCCATGCTTCATAAAAAACTACAG
GAAAACAAAAAAAGCAACTCATAA

Upstream 100 bases:

>100_bases
AAAACGCATCTGAATTTCAAGCATCTGCCATCATACTCTTTTCACAAAGATTACGGCATGACAAGAGTAACTTTTTTTCA
TCACTGACCCTTGCAAGCCG

Downstream 100 bases:

>100_bases
CATAACATCCCTATGCCTACACCATCTCTCCCGGGAGAACACCTTTTAACCAGCCGGGTTCTCAGCATGCAGGAATCTCA
GACCATGAGAATTTCAGGCC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MKRKAIYPGTFDPFTNGHLDVLDRALNIFDEVEVVIGENSQKKTLFTVNERLEMIREIVIEFPGVTVAVLHDGLLANYAR
QVEARAIVRGVRQVKDFEYEFQMSLLNRHLYPEVTTVFLMPNVKYTYVASSIIREVAMLGGDVSKFVHPCVLAMLHKKLQ
ENKKSNS

Sequences:

>Translated_167_residues
MKRKAIYPGTFDPFTNGHLDVLDRALNIFDEVEVVIGENSQKKTLFTVNERLEMIREIVIEFPGVTVAVLHDGLLANYAR
QVEARAIVRGVRQVKDFEYEFQMSLLNRHLYPEVTTVFLMPNVKYTYVASSIIREVAMLGGDVSKFVHPCVLAMLHKKLQ
ENKKSNS
>Mature_167_residues
MKRKAIYPGTFDPFTNGHLDVLDRALNIFDEVEVVIGENSQKKTLFTVNERLEMIREIVIEFPGVTVAVLHDGLLANYAR
QVEARAIVRGVRQVKDFEYEFQMSLLNRHLYPEVTTVFLMPNVKYTYVASSIIREVAMLGGDVSKFVHPCVLAMLHKKLQ
ENKKSNS

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=44.0251572327044, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_CHLPD (A1BF85)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911486.1
- ProteinModelPortal:   A1BF85
- SMR:   A1BF85
- STRING:   A1BF85
- GeneID:   4570170
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_1015
- NMPDR:   fig|290317.7.peg.1079
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 19101; Mature: 19101

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKAIYPGTFDPFTNGHLDVLDRALNIFDEVEVVIGENSQKKTLFTVNERLEMIREIVI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
EFPGVTVAVLHDGLLANYARQVEARAIVRGVRQVKDFEYEFQMSLLNRHLYPEVTTVFLM
HCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
PNVKYTYVASSIIREVAMLGGDVSKFVHPCVLAMLHKKLQENKKSNS
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRKAIYPGTFDPFTNGHLDVLDRALNIFDEVEVVIGENSQKKTLFTVNERLEMIREIVI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
EFPGVTVAVLHDGLLANYARQVEARAIVRGVRQVKDFEYEFQMSLLNRHLYPEVTTVFLM
HCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
PNVKYTYVASSIIREVAMLGGDVSKFVHPCVLAMLHKKLQENKKSNS
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA