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The map label for this gene is arpC [H]

Identifier: 119356782

GI number: 119356782

Start: 1096739

End: 1098130

Strand: Direct

Name: arpC [H]

Synonym: Cpha266_0954

Alternate gene names: 119356782

Gene position: 1096739-1098130 (Clockwise)

Preceding gene: 119356781

Following gene: 119356785

Centisome position: 35.0

GC content: 50.93

Gene sequence:

>1392_bases
ATGAAGAGGTTGCGACTGTTATTTCTGCTTGTGCTCATGGTGGTGATGTTTCCGGCACTGCCCGATTCTGTTTCAGGAGC
TGACATTCCCGGGGAAACAAAGCTTGTTCTGACGCTTGATGATGCTGTGCTGCTGGGGTTGAGCAAAAATCGCACGCTTG
AAATATCGAGACTCGACCGCCAGATGGCTGACCAGAAGGTTCGTGAAACCTGGGCGGAGGTACTGCCTAAGGTATCTACC
GGATTTACCTATACCCGATCGCTGAAGTCCTCAATTCTTTTTTTTCCTGATGTATTTTCCGGTGGTACCGGATCATCGTT
CACTCCGCTTGAAATAAGTGCCGATAATGCCGCATCAGCGACGATCGATCTGCAGCAGACGATTTTCAAGGGTACGGCTA
TCGCGGGCATCAGGGCCGCGACGATTGTTCGGAAAATAAGTGACGAAGCCTATCGCAATACCCAGGCGGCAGTCGTAGCT
GATATTAAACATTCCTATTTTGACGCACTGATTTCACGTGACCAGCTCAGGCTGATCCAGCAGAGTATAGATCGCTGGGA
AGAGGCCCGCAAGGATACGCAGGCAATGTTCCGTCAGGGTGTTGCTGCCGATATCGATACGCTCAAGGCGTTTCTGTCGG
TTGAAAATCTCAGGCCTGATCTTATACAGGCTGAGCACAGGGTTGGCTACACGATGACAAAACTTAAAAATGCAATGGGG
ATTTCGCAGGATAGCGAGGTTTTGCTTACGGGCAAACTTGAACTCTCTCCAAAAGCATATCCCGACGATATCGTTTCGGC
TTATCGCGAGGCTCTTGAGTTGCGGCCTGATATTCATCAGCTTGAGTTGCAGGTTGAGGCAGAAGATGCGAAGGTTTTTG
CCGCAAAGGCGGAACGCTTTCCTGTGATCACTGCTTTCGGACAGCTCGGTTCCCAGACGGCATTTAATGACAACAGCAGC
TTTGGCGATTCAGCCTGGCCGGTTTCCGCTTCGGTGGGTCTTCAGGTGAGTCTGCCGATTTTTACAGGATTCAGGACAAG
TGCTCTGGTCGAACAGGCAAAGATTTCCCGATTGCAAACCCGGCTTCGGCTTGAAGAGCTTAAATCAACGGCGAGGGCTG
AGGTTGAAGTGCGGCTTTCCGGGTTGCGGGAGTCGCAGAAAAGAATTTCGGTGCAATCAAAAACCATTGCGGTTGCTGAA
CGCAGCTATAAAATATCGCTGTTGCGTTTCAGGGAGGGCGTTGGCTCCCGTCTTGAGCTGACTGAGGCTGAATTGCAGTT
GGACAAGGCGAAAACCAACTATTTGCAGGCAGTGTATGATTATCTGGTTGCCAGTGTCCAGCTTGACAAGTCGCTTGGAA
GAAACCCTGTTCCGCCACCAGGGAAGGGCTGA

Upstream 100 bases:

>100_bases
GGGACCCTCTCTGAATCGTTGCGACTTGCCATTTATTTGGAATGCCGGACGACCAGGACAGCTTATGAGAGGCGCCCAAC
ATGATTGATTCTGATTACCC

Downstream 100 bases:

>100_bases
CGGCGGGCTCTTTTTATTTTTGTTTACGGACGATATAGACCAGGCTTGAGGCTTTGAGCGGGTTTGCTTTTCCGATGGCC
ATTGCCCGTATTGCTTGCAG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKRLRLLFLLVLMVVMFPALPDSVSGADIPGETKLVLTLDDAVLLGLSKNRTLEISRLDRQMADQKVRETWAEVLPKVST
GFTYTRSLKSSILFFPDVFSGGTGSSFTPLEISADNAASATIDLQQTIFKGTAIAGIRAATIVRKISDEAYRNTQAAVVA
DIKHSYFDALISRDQLRLIQQSIDRWEEARKDTQAMFRQGVAADIDTLKAFLSVENLRPDLIQAEHRVGYTMTKLKNAMG
ISQDSEVLLTGKLELSPKAYPDDIVSAYREALELRPDIHQLELQVEAEDAKVFAAKAERFPVITAFGQLGSQTAFNDNSS
FGDSAWPVSASVGLQVSLPIFTGFRTSALVEQAKISRLQTRLRLEELKSTARAEVEVRLSGLRESQKRISVQSKTIAVAE
RSYKISLLRFREGVGSRLELTEAELQLDKAKTNYLQAVYDYLVASVQLDKSLGRNPVPPPGKG

Sequences:

>Translated_463_residues
MKRLRLLFLLVLMVVMFPALPDSVSGADIPGETKLVLTLDDAVLLGLSKNRTLEISRLDRQMADQKVRETWAEVLPKVST
GFTYTRSLKSSILFFPDVFSGGTGSSFTPLEISADNAASATIDLQQTIFKGTAIAGIRAATIVRKISDEAYRNTQAAVVA
DIKHSYFDALISRDQLRLIQQSIDRWEEARKDTQAMFRQGVAADIDTLKAFLSVENLRPDLIQAEHRVGYTMTKLKNAMG
ISQDSEVLLTGKLELSPKAYPDDIVSAYREALELRPDIHQLELQVEAEDAKVFAAKAERFPVITAFGQLGSQTAFNDNSS
FGDSAWPVSASVGLQVSLPIFTGFRTSALVEQAKISRLQTRLRLEELKSTARAEVEVRLSGLRESQKRISVQSKTIAVAE
RSYKISLLRFREGVGSRLELTEAELQLDKAKTNYLQAVYDYLVASVQLDKSLGRNPVPPPGKG
>Mature_463_residues
MKRLRLLFLLVLMVVMFPALPDSVSGADIPGETKLVLTLDDAVLLGLSKNRTLEISRLDRQMADQKVRETWAEVLPKVST
GFTYTRSLKSSILFFPDVFSGGTGSSFTPLEISADNAASATIDLQQTIFKGTAIAGIRAATIVRKISDEAYRNTQAAVVA
DIKHSYFDALISRDQLRLIQQSIDRWEEARKDTQAMFRQGVAADIDTLKAFLSVENLRPDLIQAEHRVGYTMTKLKNAMG
ISQDSEVLLTGKLELSPKAYPDDIVSAYREALELRPDIHQLELQVEAEDAKVFAAKAERFPVITAFGQLGSQTAFNDNSS
FGDSAWPVSASVGLQVSLPIFTGFRTSALVEQAKISRLQTRLRLEELKSTARAEVEVRLSGLRESQKRISVQSKTIAVAE
RSYKISLLRFREGVGSRLELTEAELQLDKAKTNYLQAVYDYLVASVQLDKSLGRNPVPPPGKG

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=323, Percent_Identity=25.3869969040248, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51189; Mature: 51189

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLRLLFLLVLMVVMFPALPDSVSGADIPGETKLVLTLDDAVLLGLSKNRTLEISRLDR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCEEEHHHHHH
QMADQKVRETWAEVLPKVSTGFTYTRSLKSSILFFPDVFSGGTGSSFTPLEISADNAASA
HHHHHHHHHHHHHHCCCHHCCCCHHHHHHHCEEECCCCCCCCCCCCCCCEEEECCCCCCE
TIDLQQTIFKGTAIAGIRAATIVRKISDEAYRNTQAAVVADIKHSYFDALISRDQLRLIQ
EEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QSIDRWEEARKDTQAMFRQGVAADIDTLKAFLSVENLRPDLIQAEHRVGYTMTKLKNAMG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHC
ISQDSEVLLTGKLELSPKAYPDDIVSAYREALELRPDIHQLELQVEAEDAKVFAAKAERF
CCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCHHEEEHHHCCC
PVITAFGQLGSQTAFNDNSSFGDSAWPVSASVGLQVSLPIFTGFRTSALVEQAKISRLQT
CEEEEHHHCCCCCCCCCCCCCCCCCCCCEECCCEEEEECCCCCCHHHHHHHHHHHHHHHH
RLRLEELKSTARAEVEVRLSGLRESQKRISVQSKTIAVAERSYKISLLRFREGVGSRLEL
HHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHEEEEECCCCEEEHHHHHHCCCCCEEE
TEAELQLDKAKTNYLQAVYDYLVASVQLDKSLGRNPVPPPGKG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKRLRLLFLLVLMVVMFPALPDSVSGADIPGETKLVLTLDDAVLLGLSKNRTLEISRLDR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCEEEHHHHHH
QMADQKVRETWAEVLPKVSTGFTYTRSLKSSILFFPDVFSGGTGSSFTPLEISADNAASA
HHHHHHHHHHHHHHCCCHHCCCCHHHHHHHCEEECCCCCCCCCCCCCCCEEEECCCCCCE
TIDLQQTIFKGTAIAGIRAATIVRKISDEAYRNTQAAVVADIKHSYFDALISRDQLRLIQ
EEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QSIDRWEEARKDTQAMFRQGVAADIDTLKAFLSVENLRPDLIQAEHRVGYTMTKLKNAMG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHC
ISQDSEVLLTGKLELSPKAYPDDIVSAYREALELRPDIHQLELQVEAEDAKVFAAKAERF
CCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCHHEEEHHHCCC
PVITAFGQLGSQTAFNDNSSFGDSAWPVSASVGLQVSLPIFTGFRTSALVEQAKISRLQT
CEEEEHHHCCCCCCCCCCCCCCCCCCCCEECCCEEEEECCCCCCHHHHHHHHHHHHHHHH
RLRLEELKSTARAEVEVRLSGLRESQKRISVQSKTIAVAERSYKISLLRFREGVGSRLEL
HHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHEEEEECCCCEEEHHHHHHCCCCCEEE
TEAELQLDKAKTNYLQAVYDYLVASVQLDKSLGRNPVPPPGKG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]