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The map label for this gene is pkn1 [H]

Identifier: 119356728

GI number: 119356728

Start: 1028207

End: 1030687

Strand: Direct

Name: pkn1 [H]

Synonym: Cpha266_0900

Alternate gene names: 119356728

Gene position: 1028207-1030687 (Clockwise)

Preceding gene: 119356727

Following gene: 119356729

Centisome position: 32.81

GC content: 50.42

Gene sequence:

>2481_bases
ATGATGACCGAACCCCTGGCAACATATATTTCAGCCAATCACCAGTATCCGTTCGATGAGTTGTTTGAACTCCTTCGGGA
ACAGGGCTTCAGTTTTGGAGTTGACACCTGTGAAACAGCACATTATGTGATCATGAAAGCCATTGAGTCGGGTGACCTTG
AACGGCTCGATATGTGGTTATGTCCGGTGCTGGCCCATTCCGCAGAACAGCAGGCGACATTTTTTGAACTCTATAAACGG
CTTTTTATTCCCTTTATCGAAAAACAGTCAACGGCTATTGACAAAAAAGAGAAGCTGCCGGTTTCATCCGGAACAGGCGA
TACGGCAACAGTACGAAAACAGGAGCGGGAAACAGATAAAAAGGGCAGGGAGGAGAGTGAGAAAATCGTGGCCTCTCTGA
AAGCCCGAAGCGGCGGTTCATATACGATCGACCGCTTTGTACAATCAACGGAGATTGAGAGCGACCCGGTGCTGCTCAGG
GTGGTGCGTCAACTTCGCTATACGGAACAGTCCGGCCGCTACTCTTTTGATATTGAAAAAACAATTCATAAAACCATTCA
TGACGGCGGCATGGCCAGGCCGGTTTTTACCCCGTCCCGTCTCCATGTCGAGTATCTGATGCTCATTGACCGCCACAATT
CCCGTGACCCTCAGGCACATCTCCACAACAACCTCTATGAGACACTGAAAGCAAACAATATTTTTGTTGAACGCTTCTGG
TTCGACAATTCCCCACTCCTTTGCCGCAATCATCGTCATCCCGGTGGCATTGCGCTGTCGGAAATTCTCGGCATTCATGA
ACATGCCGCTCTTCTTCTCTTTACCGACGGCTTGCAATGTATCGATACCGGGCACGAAAGCCTGTTTGCTTGGACAGGGA
TCTTCAAACATTGGCAGCACCGATATTTTTTCAGTTCCGTGCCCCCGGTACTCTGGGGAGAGCGCGAGCGATTGCTGCAA
GGAGTGTTTCCGTTTGTTTTGCCACTTTCAGTTGAAGGAATGCAGGTTATGGCGGCCGACCTTTCGCAGATGGCCAGTGC
CGATTGCGATTGGCTGCGTTACTGGCCTGATAAAGCCGATTATGCGCGGGTTCCGATACAAACCGGGGGCAGAAAACTTG
ATTATATCGGGTTGTTTTTCACGACCGGGATAAAACGCTGGATTGCTGCCTGTGCGGTCTATCCGGAACTTGACTGGAAT
CTGACCCTCGCATTGGGCAAAATGTTTTCAACGGAAAAAAACGTTTTGCCTTCATACAACAATATCAGCCAGTTGCTCCG
TCTTGGATGGTTTATAAAGGGGAACATTCCCGACGTTTTTCGTCTTGCTCTCCTGAAAGAGTGGCTGAGCCATGAAGAGC
GTGTCCGTGTGTATCAGTTTCTTTACGACCAGCTCAGCCAGAACCTCCCTCTGGAAAGTGAACCTGATTACAGTCGCCGT
ACCCTGCAACTTGCCGTTTACGACCTGCTTGCCCAGACAAACAAAGAGCTGTTCGAAGAAAAGGCAAAACAACTGGCGAG
TATCCACGAACCGAATAGCCGCCTGCCCGATATGGTGAGCATTCATCTGATCAATGAGCATGAATACAGTCCGGTATTTT
TTGAAATCCCTGACGCTGTTTTAAAACGTATGGGCCTTGATCCTGCGCAAACCAGAAAGGCAGAAAAGGTGCCTCTGAAC
TTTGTTCGCATACCTGAAGGCGAATTTACCATGGGAAGTCCGGCAAGTGAAATTGACAGATCTGGTGATGAGACTCAGCA
CCAGGTGAAGGTGAGTGACTTTTATCTGTGTAAATATGCGGTTACTCTTGCCGGGTTCAAGGAATTTATCGAAGCATCGG
GCTATCGCACTGATGCTGAAAAAGGGGATGGCAGTTATGTGTGGGATGGTAAAAGCTGGGAGAAGAGAGCGGGAATAAAC
TGGCGCTTTGGCATATCGGGCGGTGTGCGACCTCAAAGTGAGGAGAACCACCCTGTTGTGCATGTGAGCTGGAATGACGC
TGTGGCCTATTGCAAGTGGATATCGGAAAAAACAGGACAGCAGTTTCGATTGCCAACGGAAGCTGAGTGGGAATATGCGT
GTCGAGCAGGAACAACCACACCGTTCCATACTGGCGATAACCTGACAACCGGGGAGGCGAACTATAACGGTAATTATCCG
TATAACAAAAATCCGAAAGGGGAGTACCGGGAGAACACGGTTCCGGTTGACAGTCTGGCGCCGAACGCGTGGGGGTTATA
CCATATGCATGGCAATGTGTGGGAGTGGTGTGGCGACAGGTATGGGGATAAGTATTATGATGAATGCAAAGCCAAAGGGG
TTGTTGAAAATCCGGTTGGTCCGGAAACCGGTTCGATCCGTGTGCTTCGTGGTGGTAGCTGGGGCAACTATGCGGGGTAC
TGTCGGTCGGCTAATCGCAACAGCGACACCCCCGGCGACCGCGGCAGCGACGCCGGCTTCCGCCTGGCCTTCGTCCCGTA
G

Upstream 100 bases:

>100_bases
AAAATGCGAAAACCCTTTTGAGCGGAATCTCTGTATTGGCCAAGGAAGATAGCGACTGGAAAACGGTTACCGAGGCCATA
ACAGGTCATAACATCAAGGG

Downstream 100 bases:

>100_bases
TCAGTTGGCAGCTCATGCCGACCTTTACTTTGAGCAGGAGGGGGTGCCAACATTGAGGTGAGCGGCAGCAAGGGACGCAG
CGCCGCACGCCTCAATGTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 826; Mature: 826

Protein sequence:

>826_residues
MMTEPLATYISANHQYPFDELFELLREQGFSFGVDTCETAHYVIMKAIESGDLERLDMWLCPVLAHSAEQQATFFELYKR
LFIPFIEKQSTAIDKKEKLPVSSGTGDTATVRKQERETDKKGREESEKIVASLKARSGGSYTIDRFVQSTEIESDPVLLR
VVRQLRYTEQSGRYSFDIEKTIHKTIHDGGMARPVFTPSRLHVEYLMLIDRHNSRDPQAHLHNNLYETLKANNIFVERFW
FDNSPLLCRNHRHPGGIALSEILGIHEHAALLLFTDGLQCIDTGHESLFAWTGIFKHWQHRYFFSSVPPVLWGERERLLQ
GVFPFVLPLSVEGMQVMAADLSQMASADCDWLRYWPDKADYARVPIQTGGRKLDYIGLFFTTGIKRWIAACAVYPELDWN
LTLALGKMFSTEKNVLPSYNNISQLLRLGWFIKGNIPDVFRLALLKEWLSHEERVRVYQFLYDQLSQNLPLESEPDYSRR
TLQLAVYDLLAQTNKELFEEKAKQLASIHEPNSRLPDMVSIHLINEHEYSPVFFEIPDAVLKRMGLDPAQTRKAEKVPLN
FVRIPEGEFTMGSPASEIDRSGDETQHQVKVSDFYLCKYAVTLAGFKEFIEASGYRTDAEKGDGSYVWDGKSWEKRAGIN
WRFGISGGVRPQSEENHPVVHVSWNDAVAYCKWISEKTGQQFRLPTEAEWEYACRAGTTTPFHTGDNLTTGEANYNGNYP
YNKNPKGEYRENTVPVDSLAPNAWGLYHMHGNVWEWCGDRYGDKYYDECKAKGVVENPVGPETGSIRVLRGGSWGNYAGY
CRSANRNSDTPGDRGSDAGFRLAFVP

Sequences:

>Translated_826_residues
MMTEPLATYISANHQYPFDELFELLREQGFSFGVDTCETAHYVIMKAIESGDLERLDMWLCPVLAHSAEQQATFFELYKR
LFIPFIEKQSTAIDKKEKLPVSSGTGDTATVRKQERETDKKGREESEKIVASLKARSGGSYTIDRFVQSTEIESDPVLLR
VVRQLRYTEQSGRYSFDIEKTIHKTIHDGGMARPVFTPSRLHVEYLMLIDRHNSRDPQAHLHNNLYETLKANNIFVERFW
FDNSPLLCRNHRHPGGIALSEILGIHEHAALLLFTDGLQCIDTGHESLFAWTGIFKHWQHRYFFSSVPPVLWGERERLLQ
GVFPFVLPLSVEGMQVMAADLSQMASADCDWLRYWPDKADYARVPIQTGGRKLDYIGLFFTTGIKRWIAACAVYPELDWN
LTLALGKMFSTEKNVLPSYNNISQLLRLGWFIKGNIPDVFRLALLKEWLSHEERVRVYQFLYDQLSQNLPLESEPDYSRR
TLQLAVYDLLAQTNKELFEEKAKQLASIHEPNSRLPDMVSIHLINEHEYSPVFFEIPDAVLKRMGLDPAQTRKAEKVPLN
FVRIPEGEFTMGSPASEIDRSGDETQHQVKVSDFYLCKYAVTLAGFKEFIEASGYRTDAEKGDGSYVWDGKSWEKRAGIN
WRFGISGGVRPQSEENHPVVHVSWNDAVAYCKWISEKTGQQFRLPTEAEWEYACRAGTTTPFHTGDNLTTGEANYNGNYP
YNKNPKGEYRENTVPVDSLAPNAWGLYHMHGNVWEWCGDRYGDKYYDECKAKGVVENPVGPETGSIRVLRGGSWGNYAGY
CRSANRNSDTPGDRGSDAGFRLAFVP
>Mature_826_residues
MMTEPLATYISANHQYPFDELFELLREQGFSFGVDTCETAHYVIMKAIESGDLERLDMWLCPVLAHSAEQQATFFELYKR
LFIPFIEKQSTAIDKKEKLPVSSGTGDTATVRKQERETDKKGREESEKIVASLKARSGGSYTIDRFVQSTEIESDPVLLR
VVRQLRYTEQSGRYSFDIEKTIHKTIHDGGMARPVFTPSRLHVEYLMLIDRHNSRDPQAHLHNNLYETLKANNIFVERFW
FDNSPLLCRNHRHPGGIALSEILGIHEHAALLLFTDGLQCIDTGHESLFAWTGIFKHWQHRYFFSSVPPVLWGERERLLQ
GVFPFVLPLSVEGMQVMAADLSQMASADCDWLRYWPDKADYARVPIQTGGRKLDYIGLFFTTGIKRWIAACAVYPELDWN
LTLALGKMFSTEKNVLPSYNNISQLLRLGWFIKGNIPDVFRLALLKEWLSHEERVRVYQFLYDQLSQNLPLESEPDYSRR
TLQLAVYDLLAQTNKELFEEKAKQLASIHEPNSRLPDMVSIHLINEHEYSPVFFEIPDAVLKRMGLDPAQTRKAEKVPLN
FVRIPEGEFTMGSPASEIDRSGDETQHQVKVSDFYLCKYAVTLAGFKEFIEASGYRTDAEKGDGSYVWDGKSWEKRAGIN
WRFGISGGVRPQSEENHPVVHVSWNDAVAYCKWISEKTGQQFRLPTEAEWEYACRAGTTTPFHTGDNLTTGEANYNGNYP
YNKNPKGEYRENTVPVDSLAPNAWGLYHMHGNVWEWCGDRYGDKYYDECKAKGVVENPVGPETGSIRVLRGGSWGNYAGY
CRSANRNSDTPGDRGSDAGFRLAFVP

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=288, Percent_Identity=35.7638888888889, Blast_Score=157, Evalue=5e-38,
Organism=Homo sapiens, GI257470975, Length=271, Percent_Identity=36.1623616236162, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI257470977, Length=288, Percent_Identity=32.9861111111111, Blast_Score=134, Evalue=4e-31,
Organism=Homo sapiens, GI194248087, Length=278, Percent_Identity=32.7338129496403, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI194248088, Length=293, Percent_Identity=30.3754266211604, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI226437577, Length=190, Percent_Identity=35.2631578947368, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI194248090, Length=157, Percent_Identity=32.484076433121, Blast_Score=74, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20130397, Length=292, Percent_Identity=33.9041095890411, Blast_Score=127, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 94411; Mature: 94411

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00616 HIS_ACID_PHOSPHAT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTEPLATYISANHQYPFDELFELLREQGFSFGVDTCETAHYVIMKAIESGDLERLDMWL
CCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
CPVLAHSAEQQATFFELYKRLFIPFIEKQSTAIDKKEKLPVSSGTGDTATVRKQERETDK
HHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHH
KGREESEKIVASLKARSGGSYTIDRFVQSTEIESDPVLLRVVRQLRYTEQSGRYSFDIEK
CCHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHH
TIHKTIHDGGMARPVFTPSRLHVEYLMLIDRHNSRDPQAHLHNNLYETLKANNIFVERFW
HHHHHHHCCCCCCCCCCCCHHHEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEE
FDNSPLLCRNHRHPGGIALSEILGIHEHAALLLFTDGLQCIDTGHESLFAWTGIFKHWQH
ECCCCEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHH
RYFFSSVPPVLWGERERLLQGVFPFVLPLSVEGMQVMAADLSQMASADCDWLRYWPDKAD
HHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCC
YARVPIQTGGRKLDYIGLFFTTGIKRWIAACAVYPELDWNLTLALGKMFSTEKNVLPSYN
EEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCCCCCHH
NISQLLRLGWFIKGNIPDVFRLALLKEWLSHEERVRVYQFLYDQLSQNLPLESEPDYSRR
HHHHHHHHCCEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
TLQLAVYDLLAQTNKELFEEKAKQLASIHEPNSRLPDMVSIHLINEHEYSPVFFEIPDAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEECCHHH
LKRMGLDPAQTRKAEKVPLNFVRIPEGEFTMGSPASEIDRSGDETQHQVKVSDFYLCKYA
HHHCCCCHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCCHHEEEEHHHHHHHHH
VTLAGFKEFIEASGYRTDAEKGDGSYVWDGKSWEKRAGINWRFGISGGVRPQSEENHPVV
HHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHCCCCEEEECCCCCCCCCCCCCCEE
HVSWNDAVAYCKWISEKTGQQFRLPTEAEWEYACRAGTTTPFHTGDNLTTGEANYNGNYP
EEECCCHHHHHHHHHHHCCCEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
YNKNPKGEYRENTVPVDSLAPNAWGLYHMHGNVWEWCGDRYGDKYYDECKAKGVVENPVG
CCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHCCCCCCCCCC
PETGSIRVLRGGSWGNYAGYCRSANRNSDTPGDRGSDAGFRLAFVP
CCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MMTEPLATYISANHQYPFDELFELLREQGFSFGVDTCETAHYVIMKAIESGDLERLDMWL
CCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
CPVLAHSAEQQATFFELYKRLFIPFIEKQSTAIDKKEKLPVSSGTGDTATVRKQERETDK
HHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHH
KGREESEKIVASLKARSGGSYTIDRFVQSTEIESDPVLLRVVRQLRYTEQSGRYSFDIEK
CCHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHH
TIHKTIHDGGMARPVFTPSRLHVEYLMLIDRHNSRDPQAHLHNNLYETLKANNIFVERFW
HHHHHHHCCCCCCCCCCCCHHHEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEE
FDNSPLLCRNHRHPGGIALSEILGIHEHAALLLFTDGLQCIDTGHESLFAWTGIFKHWQH
ECCCCEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHH
RYFFSSVPPVLWGERERLLQGVFPFVLPLSVEGMQVMAADLSQMASADCDWLRYWPDKAD
HHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCC
YARVPIQTGGRKLDYIGLFFTTGIKRWIAACAVYPELDWNLTLALGKMFSTEKNVLPSYN
EEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCCCCCHH
NISQLLRLGWFIKGNIPDVFRLALLKEWLSHEERVRVYQFLYDQLSQNLPLESEPDYSRR
HHHHHHHHCCEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
TLQLAVYDLLAQTNKELFEEKAKQLASIHEPNSRLPDMVSIHLINEHEYSPVFFEIPDAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEECCHHH
LKRMGLDPAQTRKAEKVPLNFVRIPEGEFTMGSPASEIDRSGDETQHQVKVSDFYLCKYA
HHHCCCCHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCCHHEEEEHHHHHHHHH
VTLAGFKEFIEASGYRTDAEKGDGSYVWDGKSWEKRAGINWRFGISGGVRPQSEENHPVV
HHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHCCCCEEEECCCCCCCCCCCCCCEE
HVSWNDAVAYCKWISEKTGQQFRLPTEAEWEYACRAGTTTPFHTGDNLTTGEANYNGNYP
EEECCCHHHHHHHHHHHCCCEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
YNKNPKGEYRENTVPVDSLAPNAWGLYHMHGNVWEWCGDRYGDKYYDECKAKGVVENPVG
CCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHCCCCCCCCCC
PETGSIRVLRGGSWGNYAGYCRSANRNSDTPGDRGSDAGFRLAFVP
CCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]