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The map label for this gene is yabD [H]

Identifier: 119356541

GI number: 119356541

Start: 805957

End: 806724

Strand: Reverse

Name: yabD [H]

Synonym: Cpha266_0706

Alternate gene names: 119356541

Gene position: 806724-805957 (Counterclockwise)

Preceding gene: 119356542

Following gene: 119356540

Centisome position: 25.74

GC content: 50.91

Gene sequence:

>768_bases
ATGTTCATTGATGCCCACTGTCATCTTTCGTTTCCGGAATTTGACCAGGATCGTTCCGAGGTGATCGAACGTCTCAATGC
AGGGGGAATTTCTCTGCTGATCGACCCGGGAACAAATAGTGATACAAGCAGAAAAGCAATTGAGCTTGCCTCCAGCCATA
CCTTCATTTACGCCAACGTCGGACTCCACCCTCATGAAGTCACCGATACTGTTAACGACTCTCTCATCAACGATTTGGCT
CTGCTTGCCCGTTCGCCAAAAGTTGTAGGTATAGGCGAAATCGGGCTTGACTACCATTATCCCGGCTACAATCGCACGGC
ACAGATGGACGCATTCCGCCGAATGCTCAATCTGGCAAAAATGCTCGATCTGCCTGCGGTTATCCATTGTCGCGATGCCT
GGGATGACATGCTTCGAATTCTCGACGACGAAAAACACTCGTCGCTCCGGGGAGTCATGCACTGTTTTTCGGGTGACACG
GCACTTGCCGGAGAGTGCCTCCGTCGAGGGTTCAAGTTATCGATTCCGGGAACGGTTACCTATAAACGGTCTCTCCTTCC
CGAAGTAATCGACTCCGTATCGCTTCACGATCTGCTTACCGAAACAGATGCGCCCTACCTTGCGCCAATTCCGCATCGAG
GAAAAAGAAATGAACCGGCATTCGTTCAATTGGTGACACAGACAATCGCATCTATAAAAAACATCCCGCTCGATGACGCC
GCTGATGCCATTGAGAGCACGGCACGGCAACTGTTTCAGTTAGCCTGA

Upstream 100 bases:

>100_bases
ATCTTCAACATTGCGGATTCAGCAATCACTATTGGTGCCTGTTTACTGATTCTTTTTCACAGCACCATTTTTCCTGACCA
GTCAGTTCAAAAAAACACCG

Downstream 100 bases:

>100_bases
ATCACACCCTCTTTTTCTCCTCTTCAATGCAAATATTTTGAAATTCATGCAAACTTCCTTAGGTTGCAAACCATAATGGA
GCAAAAAATTTTCAGGATTA

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MFIDAHCHLSFPEFDQDRSEVIERLNAGGISLLIDPGTNSDTSRKAIELASSHTFIYANVGLHPHEVTDTVNDSLINDLA
LLARSPKVVGIGEIGLDYHYPGYNRTAQMDAFRRMLNLAKMLDLPAVIHCRDAWDDMLRILDDEKHSSLRGVMHCFSGDT
ALAGECLRRGFKLSIPGTVTYKRSLLPEVIDSVSLHDLLTETDAPYLAPIPHRGKRNEPAFVQLVTQTIASIKNIPLDDA
ADAIESTARQLFQLA

Sequences:

>Translated_255_residues
MFIDAHCHLSFPEFDQDRSEVIERLNAGGISLLIDPGTNSDTSRKAIELASSHTFIYANVGLHPHEVTDTVNDSLINDLA
LLARSPKVVGIGEIGLDYHYPGYNRTAQMDAFRRMLNLAKMLDLPAVIHCRDAWDDMLRILDDEKHSSLRGVMHCFSGDT
ALAGECLRRGFKLSIPGTVTYKRSLLPEVIDSVSLHDLLTETDAPYLAPIPHRGKRNEPAFVQLVTQTIASIKNIPLDDA
ADAIESTARQLFQLA
>Mature_255_residues
MFIDAHCHLSFPEFDQDRSEVIERLNAGGISLLIDPGTNSDTSRKAIELASSHTFIYANVGLHPHEVTDTVNDSLINDLA
LLARSPKVVGIGEIGLDYHYPGYNRTAQMDAFRRMLNLAKMLDLPAVIHCRDAWDDMLRILDDEKHSSLRGVMHCFSGDT
ALAGECLRRGFKLSIPGTVTYKRSLLPEVIDSVSLHDLLTETDAPYLAPIPHRGKRNEPAFVQLVTQTIASIKNIPLDDA
ADAIESTARQLFQLA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=263, Percent_Identity=26.9961977186312, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI226061853, Length=269, Percent_Identity=26.3940520446097, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI110349730, Length=263, Percent_Identity=26.2357414448669, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI226061614, Length=252, Percent_Identity=26.1904761904762, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI225903424, Length=271, Percent_Identity=29.520295202952, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226061595, Length=226, Percent_Identity=26.5486725663717, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI14042943, Length=290, Percent_Identity=25.1724137931034, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI225903439, Length=245, Percent_Identity=25.3061224489796, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=32.5581395348837, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=34.1085271317829, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI48994985, Length=264, Percent_Identity=31.0606060606061, Blast_Score=115, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=27.4021352313167, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=27.2030651340996, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17543026, Length=251, Percent_Identity=29.4820717131474, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565396, Length=228, Percent_Identity=29.8245614035088, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24648690, Length=288, Percent_Identity=29.8611111111111, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24586117, Length=271, Percent_Identity=26.9372693726937, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221330018, Length=282, Percent_Identity=26.5957446808511, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28245; Mature: 28245

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00889 CNMP_BINDING_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDAHCHLSFPEFDQDRSEVIERLNAGGISLLIDPGTNSDTSRKAIELASSHTFIYANV
CEEECEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEC
GLHPHEVTDTVNDSLINDLALLARSPKVVGIGEIGLDYHYPGYNRTAQMDAFRRMLNLAK
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
MLDLPAVIHCRDAWDDMLRILDDEKHSSLRGVMHCFSGDTALAGECLRRGFKLSIPGTVT
HHCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCHH
YKRSLLPEVIDSVSLHDLLTETDAPYLAPIPHRGKRNEPAFVQLVTQTIASIKNIPLDDA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
ADAIESTARQLFQLA
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MFIDAHCHLSFPEFDQDRSEVIERLNAGGISLLIDPGTNSDTSRKAIELASSHTFIYANV
CEEECEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEC
GLHPHEVTDTVNDSLINDLALLARSPKVVGIGEIGLDYHYPGYNRTAQMDAFRRMLNLAK
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
MLDLPAVIHCRDAWDDMLRILDDEKHSSLRGVMHCFSGDTALAGECLRRGFKLSIPGTVT
HHCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCHH
YKRSLLPEVIDSVSLHDLLTETDAPYLAPIPHRGKRNEPAFVQLVTQTIASIKNIPLDDA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
ADAIESTARQLFQLA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]