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The map label for this gene is arnT [H]

Identifier: 119356525

GI number: 119356525

Start: 788344

End: 789888

Strand: Reverse

Name: arnT [H]

Synonym: Cpha266_0690

Alternate gene names: 119356525

Gene position: 789888-788344 (Counterclockwise)

Preceding gene: 119356526

Following gene: 119356524

Centisome position: 25.2

GC content: 49.64

Gene sequence:

>1545_bases
ATGCTGCCGGAGAGACAAAACTATAACAAAATTATCCATGCCTCGATAGTAGGGGTTCTGGTCATTGCAAGTTTTTTTTA
CGGTCTCGGTTCCGGGCCGCTCTTTGATGTTGACGAAGGGGCATTCAGCGAGGCAACCCGGGAAATGCTTGCGACCAAAA
ACTATCTGACCACCTACCTCAATGGAGTGCCACGATTTGACAAGCCTATTCTAATCTACTGGTTCCAGGCGCTTTCGGTA
ACCCTTTTCGGAATGACCGAATTCGCTTTCAGGCTCCCCTCTGCGCTTGCCAGTGCGATCTGGGCTGGAGCTATCTATCT
TTTTGCCCGAAAGGAACTCGGTTCCCGCAGGGCGTTTCTGGCCGCTGCGCTCATGATTCTCTCCCTGCAGGTGACCATCA
TTGCCAAGGCCGCCATTGCCGATGCTCTTTTGAACTGCTTTCTTGCCGTCAGCATGTTTGCTGTATACCGGCATCTGACT
ACCGGATCGAAACCTGCCAGAAACCTTGCCTTTGCGGCTATCGGGCTGGGTGTTCTGACCAAGGGTCCGATAGCGATGCT
TATTCCTCTTGCTGTTTCCTTTCTTTTCTCGCTTCAGCAGAGATCACTGAAAAAATGGCTCACGACCGTTCTGAACCCGA
CAGGCATCATCATTTTTCTTCTTATTGTGATGCCATGGTACACGCTCGAATACCTCGATCAGGGCATGGCCTTTATTCAG
GGGTTTTTTTTCAAACATAATATCAACCGTTTCAACTCCTCGCTCGAAGGGCATTCCGGATCTCTCTTCTACTATTTTCC
GGTCATTCTCCTGGGACTTATGCCATTTACCGGCCTCCTGTTCACCACGCTCTTCAACCTGAAAAAACTGCTTGCCGAGC
CGCTCAACATCTTTCTTGCAATCTGGTTCGGCTTTGTATTCATCTTTTTTTCGCTTTCCGGCACCAAACTGCCGCACTAT
ATGATCTACGGATATACGCCTCTTTTTCTCCTGATGGCAAGAGTATTCGATTCCGGCAAACACCCGAAACTGCTGGTAGT
ATGGCCTCTGCTCTTTATCACCCTCCTGGGGGCCCTCCCGTATGCTCTCCCCATGGCAATGGAACGGATTGATGATGCCT
ATATCACTGCCATCCTCCATGATGCCCGTATCATTCTTGATAGTACGTATCTCATGGTCATCGGGGTAAGCGGGCTGCTC
CTTGTGGCCACGATAACGATCCCTGTGCTGAAAGCTTCAGGAAGGCTGATCGCGCAGGGGGTTGTTCTGACGCTGCTGGT
GAATCTCTTCCTGATGCCCATTGCAGCCGAACTCCTGCAGATACCGGTCAGGGAAGCGGCAATTCTTGCCAGAAAGGAGG
GGTATAAAGTTGTGATGTGGAAAGTCTATTACCCCTCTTTTTTCGTATATTCCGAAACTTTTGCAGAGAGACGAGCTCCC
GAAAAGGGCGATATCGTGCTTACAACCGTCAAATACCTTCCAGGGTTTGACAATCCTGATGTACTCTACCAGAAGCACGG
CATTGTACTGGTAAACAATAAATAA

Upstream 100 bases:

>100_bases
GCCATTAACAAGCACTATATCAGCGATGTGCTGGCCGGGTCCCTGCTTGGTCTTGCATCAACCGCTTTCCTTTATCAACG
TTATTTCATGACACATTGTA

Downstream 100 bases:

>100_bases
ACGATTCCGTGACCATCAAACTCTCGGTAGTCATTCCGGTCATGAACGAAGAAAAGAGCATCAAACCGCTGTTCGATGCT
CTTGCGGCTGCACTCGGATC

Product: glycosyl transferase family protein

Products: NA

Alternate protein names: 4-amino-4-deoxy-L-arabinose lipid A transferase; Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; Undecaprenyl phosphate-alpha-L-Ara4N transferase [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MLPERQNYNKIIHASIVGVLVIASFFYGLGSGPLFDVDEGAFSEATREMLATKNYLTTYLNGVPRFDKPILIYWFQALSV
TLFGMTEFAFRLPSALASAIWAGAIYLFARKELGSRRAFLAAALMILSLQVTIIAKAAIADALLNCFLAVSMFAVYRHLT
TGSKPARNLAFAAIGLGVLTKGPIAMLIPLAVSFLFSLQQRSLKKWLTTVLNPTGIIIFLLIVMPWYTLEYLDQGMAFIQ
GFFFKHNINRFNSSLEGHSGSLFYYFPVILLGLMPFTGLLFTTLFNLKKLLAEPLNIFLAIWFGFVFIFFSLSGTKLPHY
MIYGYTPLFLLMARVFDSGKHPKLLVVWPLLFITLLGALPYALPMAMERIDDAYITAILHDARIILDSTYLMVIGVSGLL
LVATITIPVLKASGRLIAQGVVLTLLVNLFLMPIAAELLQIPVREAAILARKEGYKVVMWKVYYPSFFVYSETFAERRAP
EKGDIVLTTVKYLPGFDNPDVLYQKHGIVLVNNK

Sequences:

>Translated_514_residues
MLPERQNYNKIIHASIVGVLVIASFFYGLGSGPLFDVDEGAFSEATREMLATKNYLTTYLNGVPRFDKPILIYWFQALSV
TLFGMTEFAFRLPSALASAIWAGAIYLFARKELGSRRAFLAAALMILSLQVTIIAKAAIADALLNCFLAVSMFAVYRHLT
TGSKPARNLAFAAIGLGVLTKGPIAMLIPLAVSFLFSLQQRSLKKWLTTVLNPTGIIIFLLIVMPWYTLEYLDQGMAFIQ
GFFFKHNINRFNSSLEGHSGSLFYYFPVILLGLMPFTGLLFTTLFNLKKLLAEPLNIFLAIWFGFVFIFFSLSGTKLPHY
MIYGYTPLFLLMARVFDSGKHPKLLVVWPLLFITLLGALPYALPMAMERIDDAYITAILHDARIILDSTYLMVIGVSGLL
LVATITIPVLKASGRLIAQGVVLTLLVNLFLMPIAAELLQIPVREAAILARKEGYKVVMWKVYYPSFFVYSETFAERRAP
EKGDIVLTTVKYLPGFDNPDVLYQKHGIVLVNNK
>Mature_514_residues
MLPERQNYNKIIHASIVGVLVIASFFYGLGSGPLFDVDEGAFSEATREMLATKNYLTTYLNGVPRFDKPILIYWFQALSV
TLFGMTEFAFRLPSALASAIWAGAIYLFARKELGSRRAFLAAALMILSLQVTIIAKAAIADALLNCFLAVSMFAVYRHLT
TGSKPARNLAFAAIGLGVLTKGPIAMLIPLAVSFLFSLQQRSLKKWLTTVLNPTGIIIFLLIVMPWYTLEYLDQGMAFIQ
GFFFKHNINRFNSSLEGHSGSLFYYFPVILLGLMPFTGLLFTTLFNLKKLLAEPLNIFLAIWFGFVFIFFSLSGTKLPHY
MIYGYTPLFLLMARVFDSGKHPKLLVVWPLLFITLLGALPYALPMAMERIDDAYITAILHDARIILDSTYLMVIGVSGLL
LVATITIPVLKASGRLIAQGVVLTLLVNLFLMPIAAELLQIPVREAAILARKEGYKVVMWKVYYPSFFVYSETFAERRAP
EKGDIVLTTVKYLPGFDNPDVLYQKHGIVLVNNK

Specific function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG1807

COG function: function code M; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 83 family [H]

Homologues:

Organism=Escherichia coli, GI1788591, Length=306, Percent_Identity=28.1045751633987, Blast_Score=115, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022839
- InterPro:   IPR003342 [H]

Pfam domain/function: PF02366 PMT [H]

EC number: =2.4.2.43 [H]

Molecular weight: Translated: 57438; Mature: 57438

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCEEEEEEECCCCCCCCCCEEEECCEEEEECC
>Mature Secondary Structure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CCCCEEEEEEECCCCCCCCCCEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12219091 [H]