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The map label for this gene is uppP

Identifier: 119356500

GI number: 119356500

Start: 758500

End: 759348

Strand: Reverse

Name: uppP

Synonym: Cpha266_0665

Alternate gene names: 119356500

Gene position: 759348-758500 (Counterclockwise)

Preceding gene: 119356501

Following gene: 119356499

Centisome position: 24.23

GC content: 50.77

Gene sequence:

>849_bases
ATGACCCTCTTTGAATCCATCGTTCTCGGCGTTGTTCAGGGACTGACTGAGTTTTTGCCCGTCAGCAGCACAGCCCATCT
GAGAATCATTCCGGCACTTGCAGGATGGGAAGATCCCGGAGCGGCATTCACGGCTGTTGTGCAGCTCGGAACCCTTGCTG
CCGTCCTGATCTATTTCTACAAAGATATTTATGCCATTCTTGCCGCCGTTATTCAGGGAATCATGAAAGGCCGTCCTTTT
GATACTCACGAAGCTGCCATGGGGTGGATGATTGCCGTGGGAACCCTGCCCATCGTCATTTGCGGCCTGCTCTTCAAAAC
AGAAATCGAAACAAGCCTGCGCTCTCTCTACTGGGTAAGCGGCGCACTGATAGGCTTTGCGCTTCTTCTTCTCGTTGCCG
AATGGAGCGTAAAAAAACGTCTCAAGCAGAACATGTCCATGACGTCAATGGATACTATCGGCTGGAAAGAGGCGATTTTC
ACGGGATTTGCCCAATGCCTTGCCCTTATTCCGGGAGCTTCACGTTCAGGGGTAACCATTACCGGCGGTCTGTTTTTAAA
CATGTCACGGGAATCCGCAGCGCGTTTCTCTTTTCTTCTCTCGCTTCCGTCAGTCTTTGCCGCAGCACTTTTTGAGCTGT
ATCACACCTGGGATATCATCGCATCTTCAGCGGGAAGCATCGCGGCAATCACTGCAGCGACCATCACAGCAGGAATCACC
GGATATCTGTCGATCGCTTTTCTCATCAGCTATCTGAAAAAGCACACCACATCAATATTCATTATCTACCGCATCATCCT
CGGTGCCGGAATACTGAGTTTGATTGCTGCTGGCAGGCTTCAGCCATAA

Upstream 100 bases:

>100_bases
CGCTCAGCCACCGCTCGCTTGCCGTTCAGAAAGCCATTACCGAACTCAGGAATATTTTTGAACAACAGTGCATTCCCTTA
ACCAACTCCAGCACACATCA

Downstream 100 bases:

>100_bases
AAGAACCGATGTAAACCTGTTCAACGGTTTTACCGAATCGTCGGTTCTTTCACGCCTCGTACTGAAATCGCATACAACGG
CTTTCCCCGGTTTCAATAAT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTLFESIVLGVVQGLTEFLPVSSTAHLRIIPALAGWEDPGAAFTAVVQLGTLAAVLIYFYKDIYAILAAVIQGIMKGRPF
DTHEAAMGWMIAVGTLPIVICGLLFKTEIETSLRSLYWVSGALIGFALLLLVAEWSVKKRLKQNMSMTSMDTIGWKEAIF
TGFAQCLALIPGASRSGVTITGGLFLNMSRESAARFSFLLSLPSVFAAALFELYHTWDIIASSAGSIAAITAATITAGIT
GYLSIAFLISYLKKHTTSIFIIYRIILGAGILSLIAAGRLQP

Sequences:

>Translated_282_residues
MTLFESIVLGVVQGLTEFLPVSSTAHLRIIPALAGWEDPGAAFTAVVQLGTLAAVLIYFYKDIYAILAAVIQGIMKGRPF
DTHEAAMGWMIAVGTLPIVICGLLFKTEIETSLRSLYWVSGALIGFALLLLVAEWSVKKRLKQNMSMTSMDTIGWKEAIF
TGFAQCLALIPGASRSGVTITGGLFLNMSRESAARFSFLLSLPSVFAAALFELYHTWDIIASSAGSIAAITAATITAGIT
GYLSIAFLISYLKKHTTSIFIIYRIILGAGILSLIAAGRLQP
>Mature_281_residues
TLFESIVLGVVQGLTEFLPVSSTAHLRIIPALAGWEDPGAAFTAVVQLGTLAAVLIYFYKDIYAILAAVIQGIMKGRPFD
THEAAMGWMIAVGTLPIVICGLLFKTEIETSLRSLYWVSGALIGFALLLLVAEWSVKKRLKQNMSMTSMDTIGWKEAIFT
GFAQCLALIPGASRSGVTITGGLFLNMSRESAARFSFLLSLPSVFAAALFELYHTWDIIASSAGSIAAITAATITAGITG
YLSIAFLISYLKKHTTSIFIIYRIILGAGILSLIAAGRLQP

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=269, Percent_Identity=35.6877323420074, Blast_Score=153, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_CHLPD (A1BE93)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911144.1
- STRING:   A1BE93
- GeneID:   4569819
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0665
- NMPDR:   fig|290317.7.peg.698
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   RYISTRT
- ProtClustDB:   PRK12554
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30220; Mature: 30089

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc64cd5c)-; HASH(0xeac8ee8)-; HASH(0xfac43d8)-; HASH(0xfac45f4)-; HASH(0xfa6975c)-; HASH(0xf069e48)-; HASH(0xfa6ceb4)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLFESIVLGVVQGLTEFLPVSSTAHLRIIPALAGWEDPGAAFTAVVQLGTLAAVLIYFY
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KDIYAILAAVIQGIMKGRPFDTHEAAMGWMIAVGTLPIVICGLLFKTEIETSLRSLYWVS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALIGFALLLLVAEWSVKKRLKQNMSMTSMDTIGWKEAIFTGFAQCLALIPGASRSGVTI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
TGGLFLNMSRESAARFSFLLSLPSVFAAALFELYHTWDIIASSAGSIAAITAATITAGIT
ECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
GYLSIAFLISYLKKHTTSIFIIYRIILGAGILSLIAAGRLQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure 
TLFESIVLGVVQGLTEFLPVSSTAHLRIIPALAGWEDPGAAFTAVVQLGTLAAVLIYFY
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KDIYAILAAVIQGIMKGRPFDTHEAAMGWMIAVGTLPIVICGLLFKTEIETSLRSLYWVS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALIGFALLLLVAEWSVKKRLKQNMSMTSMDTIGWKEAIFTGFAQCLALIPGASRSGVTI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
TGGLFLNMSRESAARFSFLLSLPSVFAAALFELYHTWDIIASSAGSIAAITAATITAGIT
ECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
GYLSIAFLISYLKKHTTSIFIIYRIILGAGILSLIAAGRLQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA