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The map label for this gene is clpX

Identifier: 119356466

GI number: 119356466

Start: 712019

End: 713329

Strand: Direct

Name: clpX

Synonym: Cpha266_0631

Alternate gene names: 119356466

Gene position: 712019-713329 (Clockwise)

Preceding gene: 119356465

Following gene: 119356467

Centisome position: 22.72

GC content: 47.06

Gene sequence:

>1311_bases
ATGACAAAAGAGCCAGTAAAAGGAAAAGGCAAAACAGGTAACGGCAATGAACAGGTTCTCTGTTCTTTTTGTGGGCGCAC
TACCCATGAAGTCAACAGCATGGTTGCTGGCCCGAATGCCTTTATCTGTGATCGCTGTATAAAAACATCCTACGAAATTT
TACGCAAGGAGATCAGCGCAATAAACCCATCCGCCAAACGTGCGCAGGAATCGACGTTTCAAACCCGTCTGATCAGTCCG
AAAGCCATCATGGAATCTCTCGGGCAGTATGTTGTCGGACAGGAAATTGCAAAAAAATCGCTTGCCGTTGCGGTATACAA
CCATTACAAAAGGATTGATTCCCAGGAATGGGCACACGATTCGGATGAAGTGGTTATAGAGAAGAGCAATATTCTTCTTA
TCGGGCCAACAGGAACAGGCAAGACTCTGCTTGCCCAGACGCTTGCCAATCTTCTCGATGTTCCCTTCACGATTGCCGAT
GCAACATCCCTCACCGAAGCCGGTTATGTTGGCGATGATGTCGAAACCATTCTTGCCCGTCTTCTTTACGCCTCGGATTT
CAATCTCGAACGTACCGAACGCGGTATTATCTATGTTGACGAAATTGACAAGATAGCCCGTAAATCAGCCAATGTATCAA
TTACCAGAGATGTTTCCGGCGAAGGGGTTCAGCAGGCGCTTTTAAAGATACTCGAAGGATCCGTAGTCGGTGTTCCTCCA
AAAGGAGGCCGGAAACATCCCGAACAGCAGCTCATCAACATCAATACCCGCAATATTCTTTTTATTTGCGGCGGCGCCTT
CGAAGGGCTCGACAAGCTTATAGCAAGAAGAGTATCAAAATCCTCCATGGGATTTGGCTCGAAGGTTAAAAACAAACACA
CCGGATACGATCCTGAAATTCTCAGGTTTGTCACTCAGGATGACCTGCACGAATATGGACTTATTCCCGAATTTATCGGC
AGACTCCCGGTGATTTCAACCCTTGATCCCCTTGACGAAACAGCTCTTCGAAGCATCCTCGTAGAACCGAAAAACGCCAT
TATCAAACAGTATAAAAAACTCTTTGAAATGGATGGGGTTGAGCTCGAATTTACCGATGAAGCTCTCGACAAGGTAGTCG
ATATCGCAATCGACAGAGGAACAGGCGCCCGTGCGCTCCGTTCGGTTCTTGAAAGCGTGATGATCGATATCATGTTCGAG
CTTCCGACCCTCAAAGGAGTCAAAAAGTGTGTTATAACCGCAGACACGATTGAAAACCGCTCCGAGCCCGAGTTCTATTC
AGGCGACGGCAAGAAGAAGAAAATCGCGTAA

Upstream 100 bases:

>100_bases
ATCCCCGGCTGAGTCTTGCCATACAGCATGTGCTTGACTCTCTTGCCAGGATGGGCATTTAAAGAATACACAAACTATTA
CGCAAAGGCGATATCAATAC

Downstream 100 bases:

>100_bases
AACGTCCCTGAAGTCGTTTTGTTTTTTATCTGCGAAATTATATATTAACACCCTTTCAGAGAGGACGATTAGCTCAGTTG
GTTAGAGCGCTACATTGACA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTKEPVKGKGKTGNGNEQVLCSFCGRTTHEVNSMVAGPNAFICDRCIKTSYEILRKEISAINPSAKRAQESTFQTRLISP
KAIMESLGQYVVGQEIAKKSLAVAVYNHYKRIDSQEWAHDSDEVVIEKSNILLIGPTGTGKTLLAQTLANLLDVPFTIAD
ATSLTEAGYVGDDVETILARLLYASDFNLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGSVVGVPP
KGGRKHPEQQLININTRNILFICGGAFEGLDKLIARRVSKSSMGFGSKVKNKHTGYDPEILRFVTQDDLHEYGLIPEFIG
RLPVISTLDPLDETALRSILVEPKNAIIKQYKKLFEMDGVELEFTDEALDKVVDIAIDRGTGARALRSVLESVMIDIMFE
LPTLKGVKKCVITADTIENRSEPEFYSGDGKKKKIA

Sequences:

>Translated_436_residues
MTKEPVKGKGKTGNGNEQVLCSFCGRTTHEVNSMVAGPNAFICDRCIKTSYEILRKEISAINPSAKRAQESTFQTRLISP
KAIMESLGQYVVGQEIAKKSLAVAVYNHYKRIDSQEWAHDSDEVVIEKSNILLIGPTGTGKTLLAQTLANLLDVPFTIAD
ATSLTEAGYVGDDVETILARLLYASDFNLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGSVVGVPP
KGGRKHPEQQLININTRNILFICGGAFEGLDKLIARRVSKSSMGFGSKVKNKHTGYDPEILRFVTQDDLHEYGLIPEFIG
RLPVISTLDPLDETALRSILVEPKNAIIKQYKKLFEMDGVELEFTDEALDKVVDIAIDRGTGARALRSVLESVMIDIMFE
LPTLKGVKKCVITADTIENRSEPEFYSGDGKKKKIA
>Mature_435_residues
TKEPVKGKGKTGNGNEQVLCSFCGRTTHEVNSMVAGPNAFICDRCIKTSYEILRKEISAINPSAKRAQESTFQTRLISPK
AIMESLGQYVVGQEIAKKSLAVAVYNHYKRIDSQEWAHDSDEVVIEKSNILLIGPTGTGKTLLAQTLANLLDVPFTIADA
TSLTEAGYVGDDVETILARLLYASDFNLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGSVVGVPPK
GGRKHPEQQLININTRNILFICGGAFEGLDKLIARRVSKSSMGFGSKVKNKHTGYDPEILRFVTQDDLHEYGLIPEFIGR
LPVISTLDPLDETALRSILVEPKNAIIKQYKKLFEMDGVELEFTDEALDKVVDIAIDRGTGARALRSVLESVMIDIMFEL
PTLKGVKKCVITADTIENRSEPEFYSGDGKKKKIA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=327, Percent_Identity=46.177370030581, Blast_Score=294, Evalue=1e-79,
Organism=Escherichia coli, GI1786642, Length=422, Percent_Identity=54.739336492891, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI1790366, Length=230, Percent_Identity=32.1739130434783, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982905, Length=292, Percent_Identity=45.2054794520548, Blast_Score=263, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI71982908, Length=292, Percent_Identity=45.2054794520548, Blast_Score=263, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI71988663, Length=393, Percent_Identity=38.9312977099237, Blast_Score=261, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=253, Percent_Identity=40.3162055335968, Blast_Score=181, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6319704, Length=478, Percent_Identity=36.6108786610879, Blast_Score=267, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24648291, Length=333, Percent_Identity=43.2432432432432, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI24648289, Length=333, Percent_Identity=43.2432432432432, Blast_Score=281, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_CHLPD (A1BE59)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911110.1
- ProteinModelPortal:   A1BE59
- STRING:   A1BE59
- GeneID:   4569784
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0631
- NMPDR:   fig|290317.7.peg.664
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 48009; Mature: 47878

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEPVKGKGKTGNGNEQVLCSFCGRTTHEVNSMVAGPNAFICDRCIKTSYEILRKEISA
CCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
INPSAKRAQESTFQTRLISPKAIMESLGQYVVGQEIAKKSLAVAVYNHYKRIDSQEWAHD
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
SDEVVIEKSNILLIGPTGTGKTLLAQTLANLLDVPFTIADATSLTEAGYVGDDVETILAR
CCCEEEEECCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHCCCCCCCHHHHHHH
LLYASDFNLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGSVVGVPP
HHHHCCCCCCHHCCCEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEECCC
KGGRKHPEQQLININTRNILFICGGAFEGLDKLIARRVSKSSMGFGSKVKNKHTGYDPEI
CCCCCCCHHHEEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHH
LRFVTQDDLHEYGLIPEFIGRLPVISTLDPLDETALRSILVEPKNAIIKQYKKLFEMDGV
HHHHHHHHHHHHCCCHHHHCCCCCHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
ELEFTDEALDKVVDIAIDRGTGARALRSVLESVMIDIMFELPTLKGVKKCVITADTIENR
EEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEHHHHCCC
SEPEFYSGDGKKKKIA
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKEPVKGKGKTGNGNEQVLCSFCGRTTHEVNSMVAGPNAFICDRCIKTSYEILRKEISA
CCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
INPSAKRAQESTFQTRLISPKAIMESLGQYVVGQEIAKKSLAVAVYNHYKRIDSQEWAHD
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
SDEVVIEKSNILLIGPTGTGKTLLAQTLANLLDVPFTIADATSLTEAGYVGDDVETILAR
CCCEEEEECCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHCCCCCCCHHHHHHH
LLYASDFNLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGSVVGVPP
HHHHCCCCCCHHCCCEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEECCC
KGGRKHPEQQLININTRNILFICGGAFEGLDKLIARRVSKSSMGFGSKVKNKHTGYDPEI
CCCCCCCHHHEEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHH
LRFVTQDDLHEYGLIPEFIGRLPVISTLDPLDETALRSILVEPKNAIIKQYKKLFEMDGV
HHHHHHHHHHHHCCCHHHHCCCCCHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
ELEFTDEALDKVVDIAIDRGTGARALRSVLESVMIDIMFELPTLKGVKKCVITADTIENR
EEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEHHHHCCC
SEPEFYSGDGKKKKIA
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA