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The map label for this gene is gacS [H]

Identifier: 119356453

GI number: 119356453

Start: 688486

End: 692682

Strand: Direct

Name: gacS [H]

Synonym: Cpha266_0617

Alternate gene names: 119356453

Gene position: 688486-692682 (Clockwise)

Preceding gene: 119356452

Following gene: 119356455

Centisome position: 21.97

GC content: 44.56

Gene sequence:

>4197_bases
GTGAAAAAAAACTATACAATAAGCCTCCTTACAGCGGGATTTCTATTTGTTGGTTATCTGCTTGTCTGGTTGTCGGTCTA
TCGCGCTGATCATCAGTTGCGCGAACAATTGCTCAAGGATGTCTATGCCGTTGCTCGGAATATGGACAAAGAACAGATAA
AGGCTCTTTCCGGGACATCAGCAGATCGATTAAATCCCCACTACATCGATCTTAAAGCAAAACTTTCCAGTGGATGCAAA
TCCCGGACAAAATGTCGTTTTTTGTATTTGCTTGGAAGAAAAAGTGATAAAACGATATTCTTTCTTGTCGATTCGGAATT
GACGGGTTCCTCCGAGATATCGCCTCCCGGTCAGGTTTATGATGAGGCATCTTCGGTATTACAGCGTGTTTTCAGAACCG
GTCATGCCGATTCGGAGGGTCCGTTGCCTGATCGATGGGGCGTATGGGTAACCGGCTTTGTTCCTCTTGTCGATCAGCAA
AGCGAAAAGGTCGTTGCCGTGCTCGGTATGGATGTTGATGCTGCCGATTGGACACTTGATATAGCCGCCCGTTCAGCATT
GCCCATAGGAGTCGTGATCATCATTATTATCGTTATTGTCACTATTCTTCAGTCAACCCGTCATCGAGAGATTACATCAA
GTCCTTTTCTGAGACGACTTTTGCCAGTGCTTCTTGCCGTATTGTTCTTTCTTTTTTTTGGATTCGGCGTGCTTTTATGG
TGGTTGCAGGAACGACGAATTGAAGAGGTTGTTCATCAGACGGAAAAAGAGGTTTTTACCGTATTTCAAAATGCACTTAT
GGTACAGTCGGAAGGGCTTGAAATTGCTTTGAATATGATTTGTACTGATAATACGGTTGCCGATGAACTGAAAAGCCGCA
ATAGCGAGATCCTCTATTCGAAATACGAACCGCTTTTCAGACATCTTCAAGATAAGCACGGGGTCTCTTTTTTTTGTTTT
ATGGATTCTTCCCGCAAATGTCTGCTGCGTTTGCATAAACCGGAAAAGTCCGGTGATCGTATCAGTCGCTTTACCCTTCT
TGAAGCTCAAAAAACAGGTCTTTTTTCAAACGGTCTGGAGCTTGATCCCAAAGGTCTTTTGACCCTGAGGGTCGTGATGC
CTGTTTTTCAAAAAGGGAGGATTGTCGGTTTTATTGATGTTGCCAAAGAGATTGAAGCGGTTATTAACCGTGTTCATTAT
CAGCCGGGTCTTGGCATTGCACTTATTGTCGATAAAAAGTTTCTTCATAGAGGTGATTGGGAAAAGGCAATGCATGCGCT
TGGAAGAAAAACCGAGTGGGATCGATTCAGAGATGAAGTTCAGATTTATAATACGTTTGGCTATTTTCCCGAAGCATTCG
ATTTTTCTCTGGCCTCTTCAGACTCTGTAGCGTTCTATCGCAGCCGGGCAGTAACATGGCAAGGAAAATCCTGGAGGCTT
AATTTCCTTCCGCTTGAAGACGCATCAGGCAGAACAATCGGAAGAATGCTTGTGATTCAGGATGTTTCGTTTTATCAGGC
GGGCATCTTTCGAATGATCACTCTTGCGGGGATTGCACTTCTTGTTATTCTTTCGTTGCTTTTCGGCTTTCTGTTTGTTG
TTTTAAAGCGAATCGACAGAGGTGTTATCAATCGGGAGCAGGAGCTCATAGATAGTCGTGAACAGTACAGGCTTGCCGTT
AACGGAAGTAATGATGGAATTTGGGACTGGGATATGAGAAGCGACACCTTGTATCTTTCACCTAAATGGAAAAAGACGCT
TGGATATGAAGATGATGACCTTTCAAATATCTATAAGACATTTGAAGATCTGGTTCATCCCGAAGACAAGCCGGTATTCA
GAACGTATCTTGACCGATACCTGAATGGTGAAATTCCCCTGTTTAATATTGAGTTCAGAATTCGGCACAAGGATGGTGCT
TATGTATGGATTCTTGGGCGGGGTGAGGTGCTTCGTGACAAATCCGGTTCCCCATACAGGATGGCTGGTTCCATGAGCGA
TATTACCGGCAGGAAAAAAGATGAGGATGAACTGAAACGACGTTCTGCTTTTCAGCTTGTGGTGATGGATCTGGCAATCG
GATTTGTCAATACGCCACTTGACGAGCTTGATCGATCCATAGAGAGAGCGCTTGCTCTTGTCGGCGAGTTTTTGCAGGTT
GATCGTTCCTACCTTTTTCGTTATGATTTTGCCAACGGGACGATGAGCAACACACATGAATGGTGTTCAGAAGGAATCGC
TCCTGAAAAAAATAATCTTCAGAACCTTCTTAACTCAATTATCCCTGACTGGGTTGCAACCCATCTTGCGGGCAGAATTG
TTCACATTTCAAGCGTTGATGCTCTGGATGATGAAAGTGCCCTCAAAATGATATTGGCATCGCAGGGCATCAAGACACTG
ATTTCCCTTCCGCTCATTTATCATGAACACTGTTTTGGTTTTGTAGGGTTTGATGCCGTAAGAGAAGTGAAAAAATGGGG
CGATGATGAAATCTCACTGCTCCGGGTTTTAGCGGAGTTATTTACCAATGCGGAACTGCGTTTCCGTCATGAGACAGCTC
TTGTTGATGCCCGATATGCTGCCGAATCAGCAAATCGAGCTAAAAGCGAATTTCTTGCCAATATGAGTCATGAAATCCGC
ACTCCGATGAATGGCGTGATTGGAATGGCAAATCTGCTTCTTGATACGGATCTTTCTGATGAACAGAGGGATTTTGCGGA
CATGCTTCTTGCGAGCGGAGAGTCCCTGTTAACGGTTATCAATGATATTCTTGATTTTTCAAAAATTGAGGCAGGAAAGC
TTGAGTTGGAACATATCGTTTTTGATCTTCGTAAGCTCCTGGAGAGTTTTGGCGCGGTTATGGGTCTCAAAGCAGTTGAG
AAAAACCTTGAATTCAACTGTGTTGTATCTCCTGAAGTTCCGGTATTTTTCAAAGGCGATCCCGGCAGGATTCGGCAGAT
TCTTAATAATCTTGCCGGCAACGCAATCAAATTCACTCAAAACGGTAACGTAACTGTTGCCGTATCCATGCAGTCTGAAA
ATAATGGTGATGCTGTTCTTCGTTTTTCTGTAAAAGATACCGGTATAGGAATACCGGAGGCAAAGCTTGACAGATTATTC
AAAAGTTTTACGCAGGTTGATGCATCAACAACAAGAAAGTATGGCGGGACGGGTCTTGGTCTTGCAATCAGCAGGCAATT
GGTTGAGCTTATGGGCGGGAAAATTGGTGTGATCAGTCATGAGGGCAATGGTTCCGAGTTCTGGTTTACGATTTTTTTGA
AAAAGCAGCCGTTTTACAGCACTATCGAAACGCAGCCGACGTCGGCGTTTGCCGGAATCAGGGCTCTTGTTGTCGATGAT
AATGCTGCAAATCGCAAAATGCTGAAAGCTCTGCTTTCATCATTGGATATCCGTGTTACTGAAGCATCCGGTGGCGATGC
TGCTCTGGGAGAACTTCGGAGCGCTTTCAAAAGCGGCGATCCCTTTGCGCTGGCCATTATTGATATGCAGATGCCGGATA
TGGATGGTTTTATGCTCGGTCAAACAATAAAAGAGGATTTGCTTTTGCGCAATACGGAGCTCTTTCTTATGAGTCCGGTC
GGTACATTAAATCAACGTGAAGAGTATCACCGGGCAGGGTTTTCTGCCAATCTGTCAAAGCCTGTCGGTCAACTGGAACT
TGTTGCGGCAATAAACAAAGTTGTTTTCAATCATGATAACCAATCGGGAAGTCGAAATCCATCGATAAGTTATCCGGTAA
CAGAAGAAGGTGAACCTCCGATGGTTCCTGTTGGAAAACTGGAGCATTACCGTATTCTGCTTGCTGAAGACAGTCGTGTC
AACCAGATGGTGGTTATAGGGGTACTGACGAAGTTTGGATATGGTGTCGATGTGGTTTCAAATGGGCAGGAGTGTGTTGA
TGTCCTCCAAAAGAGAACATATGATCTGGTGTTAATGGATGTTCAGATGCCTGTTATGGATGGATTGAACGCAACAGGAA
TTATCAGAGATCCGGCATCAAAGGTTCTCGATCACAACATTCCGGTTATTGCTTTAACAGCGCATGCCATGCAGGGTGAC
AGGGAGAGTTGTCTTTATGCGGGGATGAATGACTATATCTCAAAGCCGATTGATGCCTCTGTTCTCACCGAAACCATCAG
CAAGTGGCTGCCGGTTAAGCCGGATTCGCCTGCATAA

Upstream 100 bases:

>100_bases
TCGAAAGAGGATGGAAGAAGTTGATAGCATGGCATAGTGTCTGTATAGGGTTTGTTTTGCAGCCATCGCATCATTACCTG
AACAAAAAAGCGGGTTTTTG

Downstream 100 bases:

>100_bases
GAGGCGGGGCGGATGTACAATTATAGCTTGTTTTGAAAAAGATATTTGTCTCATATTCATTCAGGAACTTTTCTCCCATT
CGATAAAAAGATCGTTCAGC

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1398; Mature: 1398

Protein sequence:

>1398_residues
MKKNYTISLLTAGFLFVGYLLVWLSVYRADHQLREQLLKDVYAVARNMDKEQIKALSGTSADRLNPHYIDLKAKLSSGCK
SRTKCRFLYLLGRKSDKTIFFLVDSELTGSSEISPPGQVYDEASSVLQRVFRTGHADSEGPLPDRWGVWVTGFVPLVDQQ
SEKVVAVLGMDVDAADWTLDIAARSALPIGVVIIIIIVIVTILQSTRHREITSSPFLRRLLPVLLAVLFFLFFGFGVLLW
WLQERRIEEVVHQTEKEVFTVFQNALMVQSEGLEIALNMICTDNTVADELKSRNSEILYSKYEPLFRHLQDKHGVSFFCF
MDSSRKCLLRLHKPEKSGDRISRFTLLEAQKTGLFSNGLELDPKGLLTLRVVMPVFQKGRIVGFIDVAKEIEAVINRVHY
QPGLGIALIVDKKFLHRGDWEKAMHALGRKTEWDRFRDEVQIYNTFGYFPEAFDFSLASSDSVAFYRSRAVTWQGKSWRL
NFLPLEDASGRTIGRMLVIQDVSFYQAGIFRMITLAGIALLVILSLLFGFLFVVLKRIDRGVINREQELIDSREQYRLAV
NGSNDGIWDWDMRSDTLYLSPKWKKTLGYEDDDLSNIYKTFEDLVHPEDKPVFRTYLDRYLNGEIPLFNIEFRIRHKDGA
YVWILGRGEVLRDKSGSPYRMAGSMSDITGRKKDEDELKRRSAFQLVVMDLAIGFVNTPLDELDRSIERALALVGEFLQV
DRSYLFRYDFANGTMSNTHEWCSEGIAPEKNNLQNLLNSIIPDWVATHLAGRIVHISSVDALDDESALKMILASQGIKTL
ISLPLIYHEHCFGFVGFDAVREVKKWGDDEISLLRVLAELFTNAELRFRHETALVDARYAAESANRAKSEFLANMSHEIR
TPMNGVIGMANLLLDTDLSDEQRDFADMLLASGESLLTVINDILDFSKIEAGKLELEHIVFDLRKLLESFGAVMGLKAVE
KNLEFNCVVSPEVPVFFKGDPGRIRQILNNLAGNAIKFTQNGNVTVAVSMQSENNGDAVLRFSVKDTGIGIPEAKLDRLF
KSFTQVDASTTRKYGGTGLGLAISRQLVELMGGKIGVISHEGNGSEFWFTIFLKKQPFYSTIETQPTSAFAGIRALVVDD
NAANRKMLKALLSSLDIRVTEASGGDAALGELRSAFKSGDPFALAIIDMQMPDMDGFMLGQTIKEDLLLRNTELFLMSPV
GTLNQREEYHRAGFSANLSKPVGQLELVAAINKVVFNHDNQSGSRNPSISYPVTEEGEPPMVPVGKLEHYRILLAEDSRV
NQMVVIGVLTKFGYGVDVVSNGQECVDVLQKRTYDLVLMDVQMPVMDGLNATGIIRDPASKVLDHNIPVIALTAHAMQGD
RESCLYAGMNDYISKPIDASVLTETISKWLPVKPDSPA

Sequences:

>Translated_1398_residues
MKKNYTISLLTAGFLFVGYLLVWLSVYRADHQLREQLLKDVYAVARNMDKEQIKALSGTSADRLNPHYIDLKAKLSSGCK
SRTKCRFLYLLGRKSDKTIFFLVDSELTGSSEISPPGQVYDEASSVLQRVFRTGHADSEGPLPDRWGVWVTGFVPLVDQQ
SEKVVAVLGMDVDAADWTLDIAARSALPIGVVIIIIIVIVTILQSTRHREITSSPFLRRLLPVLLAVLFFLFFGFGVLLW
WLQERRIEEVVHQTEKEVFTVFQNALMVQSEGLEIALNMICTDNTVADELKSRNSEILYSKYEPLFRHLQDKHGVSFFCF
MDSSRKCLLRLHKPEKSGDRISRFTLLEAQKTGLFSNGLELDPKGLLTLRVVMPVFQKGRIVGFIDVAKEIEAVINRVHY
QPGLGIALIVDKKFLHRGDWEKAMHALGRKTEWDRFRDEVQIYNTFGYFPEAFDFSLASSDSVAFYRSRAVTWQGKSWRL
NFLPLEDASGRTIGRMLVIQDVSFYQAGIFRMITLAGIALLVILSLLFGFLFVVLKRIDRGVINREQELIDSREQYRLAV
NGSNDGIWDWDMRSDTLYLSPKWKKTLGYEDDDLSNIYKTFEDLVHPEDKPVFRTYLDRYLNGEIPLFNIEFRIRHKDGA
YVWILGRGEVLRDKSGSPYRMAGSMSDITGRKKDEDELKRRSAFQLVVMDLAIGFVNTPLDELDRSIERALALVGEFLQV
DRSYLFRYDFANGTMSNTHEWCSEGIAPEKNNLQNLLNSIIPDWVATHLAGRIVHISSVDALDDESALKMILASQGIKTL
ISLPLIYHEHCFGFVGFDAVREVKKWGDDEISLLRVLAELFTNAELRFRHETALVDARYAAESANRAKSEFLANMSHEIR
TPMNGVIGMANLLLDTDLSDEQRDFADMLLASGESLLTVINDILDFSKIEAGKLELEHIVFDLRKLLESFGAVMGLKAVE
KNLEFNCVVSPEVPVFFKGDPGRIRQILNNLAGNAIKFTQNGNVTVAVSMQSENNGDAVLRFSVKDTGIGIPEAKLDRLF
KSFTQVDASTTRKYGGTGLGLAISRQLVELMGGKIGVISHEGNGSEFWFTIFLKKQPFYSTIETQPTSAFAGIRALVVDD
NAANRKMLKALLSSLDIRVTEASGGDAALGELRSAFKSGDPFALAIIDMQMPDMDGFMLGQTIKEDLLLRNTELFLMSPV
GTLNQREEYHRAGFSANLSKPVGQLELVAAINKVVFNHDNQSGSRNPSISYPVTEEGEPPMVPVGKLEHYRILLAEDSRV
NQMVVIGVLTKFGYGVDVVSNGQECVDVLQKRTYDLVLMDVQMPVMDGLNATGIIRDPASKVLDHNIPVIALTAHAMQGD
RESCLYAGMNDYISKPIDASVLTETISKWLPVKPDSPA
>Mature_1398_residues
MKKNYTISLLTAGFLFVGYLLVWLSVYRADHQLREQLLKDVYAVARNMDKEQIKALSGTSADRLNPHYIDLKAKLSSGCK
SRTKCRFLYLLGRKSDKTIFFLVDSELTGSSEISPPGQVYDEASSVLQRVFRTGHADSEGPLPDRWGVWVTGFVPLVDQQ
SEKVVAVLGMDVDAADWTLDIAARSALPIGVVIIIIIVIVTILQSTRHREITSSPFLRRLLPVLLAVLFFLFFGFGVLLW
WLQERRIEEVVHQTEKEVFTVFQNALMVQSEGLEIALNMICTDNTVADELKSRNSEILYSKYEPLFRHLQDKHGVSFFCF
MDSSRKCLLRLHKPEKSGDRISRFTLLEAQKTGLFSNGLELDPKGLLTLRVVMPVFQKGRIVGFIDVAKEIEAVINRVHY
QPGLGIALIVDKKFLHRGDWEKAMHALGRKTEWDRFRDEVQIYNTFGYFPEAFDFSLASSDSVAFYRSRAVTWQGKSWRL
NFLPLEDASGRTIGRMLVIQDVSFYQAGIFRMITLAGIALLVILSLLFGFLFVVLKRIDRGVINREQELIDSREQYRLAV
NGSNDGIWDWDMRSDTLYLSPKWKKTLGYEDDDLSNIYKTFEDLVHPEDKPVFRTYLDRYLNGEIPLFNIEFRIRHKDGA
YVWILGRGEVLRDKSGSPYRMAGSMSDITGRKKDEDELKRRSAFQLVVMDLAIGFVNTPLDELDRSIERALALVGEFLQV
DRSYLFRYDFANGTMSNTHEWCSEGIAPEKNNLQNLLNSIIPDWVATHLAGRIVHISSVDALDDESALKMILASQGIKTL
ISLPLIYHEHCFGFVGFDAVREVKKWGDDEISLLRVLAELFTNAELRFRHETALVDARYAAESANRAKSEFLANMSHEIR
TPMNGVIGMANLLLDTDLSDEQRDFADMLLASGESLLTVINDILDFSKIEAGKLELEHIVFDLRKLLESFGAVMGLKAVE
KNLEFNCVVSPEVPVFFKGDPGRIRQILNNLAGNAIKFTQNGNVTVAVSMQSENNGDAVLRFSVKDTGIGIPEAKLDRLF
KSFTQVDASTTRKYGGTGLGLAISRQLVELMGGKIGVISHEGNGSEFWFTIFLKKQPFYSTIETQPTSAFAGIRALVVDD
NAANRKMLKALLSSLDIRVTEASGGDAALGELRSAFKSGDPFALAIIDMQMPDMDGFMLGQTIKEDLLLRNTELFLMSPV
GTLNQREEYHRAGFSANLSKPVGQLELVAAINKVVFNHDNQSGSRNPSISYPVTEEGEPPMVPVGKLEHYRILLAEDSRV
NQMVVIGVLTKFGYGVDVVSNGQECVDVLQKRTYDLVLMDVQMPVMDGLNATGIIRDPASKVLDHNIPVIALTAHAMQGD
RESCLYAGMNDYISKPIDASVLTETISKWLPVKPDSPA

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=545, Percent_Identity=36.697247706422, Blast_Score=315, Evalue=1e-86,
Organism=Escherichia coli, GI145693157, Length=548, Percent_Identity=30.6569343065693, Blast_Score=230, Evalue=5e-61,
Organism=Escherichia coli, GI48994928, Length=482, Percent_Identity=31.9502074688797, Blast_Score=212, Evalue=1e-55,
Organism=Escherichia coli, GI87081816, Length=333, Percent_Identity=36.6366366366366, Blast_Score=199, Evalue=8e-52,
Organism=Escherichia coli, GI1788713, Length=376, Percent_Identity=34.0425531914894, Blast_Score=190, Evalue=7e-49,
Organism=Escherichia coli, GI1788393, Length=219, Percent_Identity=29.2237442922374, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1786600, Length=255, Percent_Identity=28.6274509803922, Blast_Score=88, Evalue=4e-18,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=28.6324786324786, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1786912, Length=330, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=25.7777777777778, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=234, Percent_Identity=25.2136752136752, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=24.2424242424242, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=25.4464285714286, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1790551, Length=235, Percent_Identity=26.3829787234043, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI87082012, Length=112, Percent_Identity=35.7142857142857, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=411, Percent_Identity=28.9537712895377, Blast_Score=126, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322000, Length=121, Percent_Identity=38.0165289256198, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323034, Length=141, Percent_Identity=31.2056737588652, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 156987; Mature: 156987

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNYTISLLTAGFLFVGYLLVWLSVYRADHQLREQLLKDVYAVARNMDKEQIKALSGTS
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
ADRLNPHYIDLKAKLSSGCKSRTKCRFLYLLGRKSDKTIFFLVDSELTGSSEISPPGQVY
CCCCCCEEEEEEEHHHCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHH
DEASSVLQRVFRTGHADSEGPLPDRWGVWVTGFVPLVDQQSEKVVAVLGMDVDAADWTLD
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCCCEEE
IAARSALPIGVVIIIIIVIVTILQSTRHREITSSPFLRRLLPVLLAVLFFLFFGFGVLLW
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WLQERRIEEVVHQTEKEVFTVFQNALMVQSEGLEIALNMICTDNTVADELKSRNSEILYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEECCCHHHHHHHCCCCCEEHH
KYEPLFRHLQDKHGVSFFCFMDSSRKCLLRLHKPEKSGDRISRFTLLEAQKTGLFSNGLE
HHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCHHHHEEEEHHHHCCCCCCCCC
LDPKGLLTLRVVMPVFQKGRIVGFIDVAKEIEAVINRVHYQPGLGIALIVDKKFLHRGDW
CCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCCH
EKAMHALGRKTEWDRFRDEVQIYNTFGYFPEAFDFSLASSDSVAFYRSRAVTWQGKSWRL
HHHHHHHCCCCHHHHHHHHHEEEHHHCCCCCHHCCCCCCCCCEEEEECEEEEECCCCEEE
NFLPLEDASGRTIGRMLVIQDVSFYQAGIFRMITLAGIALLVILSLLFGFLFVVLKRIDR
EEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVINREQELIDSREQYRLAVNGSNDGIWDWDMRSDTLYLSPKWKKTLGYEDDDLSNIYKT
HHHCHHHHHHCCCCCEEEEEECCCCCEEEECCCCCEEEECCCHHHHCCCCCCHHHHHHHH
FEDLVHPEDKPVFRTYLDRYLNGEIPLFNIEFRIRHKDGAYVWILGRGEVLRDKSGSPYR
HHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEEEEECCCEEECCCCCCEE
MAGSMSDITGRKKDEDELKRRSAFQLVVMDLAIGFVNTPLDELDRSIERALALVGEFLQV
ECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DRSYLFRYDFANGTMSNTHEWCSEGIAPEKNNLQNLLNSIIPDWVATHLAGRIVHISSVD
CHHHEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHCCCEEEEECCC
ALDDESALKMILASQGIKTLISLPLIYHEHCFGFVGFDAVREVKKWGDDEISLLRVLAEL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FTNAELRFRHETALVDARYAAESANRAKSEFLANMSHEIRTPMNGVIGMANLLLDTDLSD
HCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCH
EQRDFADMLLASGESLLTVINDILDFSKIEAGKLELEHIVFDLRKLLESFGAVMGLKAVE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNLEFNCVVSPEVPVFFKGDPGRIRQILNNLAGNAIKFTQNGNVTVAVSMQSENNGDAVL
HCCCEEEEECCCCCEEEECCHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECCCCCCEEE
RFSVKDTGIGIPEAKLDRLFKSFTQVDASTTRKYGGTGLGLAISRQLVELMGGKIGVISH
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEE
EGNGSEFWFTIFLKKQPFYSTIETQPTSAFAGIRALVVDDNAANRKMLKALLSSLDIRVT
CCCCCEEEEEEEEECCCCCHHCCCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHCCEEEE
EASGGDAALGELRSAFKSGDPFALAIIDMQMPDMDGFMLGQTIKEDLLLRNTELFLMSPV
ECCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCC
GTLNQREEYHRAGFSANLSKPVGQLELVAAINKVVFNHDNQSGSRNPSISYPVTEEGEPP
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
MVPVGKLEHYRILLAEDSRVNQMVVIGVLTKFGYGVDVVSNGQECVDVLQKRTYDLVLMD
CCCCCCCCEEEEEEECCCCCCCEEEEEEHHHCCCCCEEECCCHHHHHHHHHCCCEEEEEE
VQMPVMDGLNATGIIRDPASKVLDHNIPVIALTAHAMQGDRESCLYAGMNDYISKPIDAS
ECCHHHCCCCCCEEEECCHHHHHCCCCCEEEEEEHHHCCCHHHHHHCCCHHHHCCCCCHH
VLTETISKWLPVKPDSPA
HHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKNYTISLLTAGFLFVGYLLVWLSVYRADHQLREQLLKDVYAVARNMDKEQIKALSGTS
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
ADRLNPHYIDLKAKLSSGCKSRTKCRFLYLLGRKSDKTIFFLVDSELTGSSEISPPGQVY
CCCCCCEEEEEEEHHHCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHH
DEASSVLQRVFRTGHADSEGPLPDRWGVWVTGFVPLVDQQSEKVVAVLGMDVDAADWTLD
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCCCEEE
IAARSALPIGVVIIIIIVIVTILQSTRHREITSSPFLRRLLPVLLAVLFFLFFGFGVLLW
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WLQERRIEEVVHQTEKEVFTVFQNALMVQSEGLEIALNMICTDNTVADELKSRNSEILYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEECCCHHHHHHHCCCCCEEHH
KYEPLFRHLQDKHGVSFFCFMDSSRKCLLRLHKPEKSGDRISRFTLLEAQKTGLFSNGLE
HHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCHHHHEEEEHHHHCCCCCCCCC
LDPKGLLTLRVVMPVFQKGRIVGFIDVAKEIEAVINRVHYQPGLGIALIVDKKFLHRGDW
CCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCCH
EKAMHALGRKTEWDRFRDEVQIYNTFGYFPEAFDFSLASSDSVAFYRSRAVTWQGKSWRL
HHHHHHHCCCCHHHHHHHHHEEEHHHCCCCCHHCCCCCCCCCEEEEECEEEEECCCCEEE
NFLPLEDASGRTIGRMLVIQDVSFYQAGIFRMITLAGIALLVILSLLFGFLFVVLKRIDR
EEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVINREQELIDSREQYRLAVNGSNDGIWDWDMRSDTLYLSPKWKKTLGYEDDDLSNIYKT
HHHCHHHHHHCCCCCEEEEEECCCCCEEEECCCCCEEEECCCHHHHCCCCCCHHHHHHHH
FEDLVHPEDKPVFRTYLDRYLNGEIPLFNIEFRIRHKDGAYVWILGRGEVLRDKSGSPYR
HHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEEEEECCCEEECCCCCCEE
MAGSMSDITGRKKDEDELKRRSAFQLVVMDLAIGFVNTPLDELDRSIERALALVGEFLQV
ECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DRSYLFRYDFANGTMSNTHEWCSEGIAPEKNNLQNLLNSIIPDWVATHLAGRIVHISSVD
CHHHEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHCCCEEEEECCC
ALDDESALKMILASQGIKTLISLPLIYHEHCFGFVGFDAVREVKKWGDDEISLLRVLAEL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FTNAELRFRHETALVDARYAAESANRAKSEFLANMSHEIRTPMNGVIGMANLLLDTDLSD
HCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCH
EQRDFADMLLASGESLLTVINDILDFSKIEAGKLELEHIVFDLRKLLESFGAVMGLKAVE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNLEFNCVVSPEVPVFFKGDPGRIRQILNNLAGNAIKFTQNGNVTVAVSMQSENNGDAVL
HCCCEEEEECCCCCEEEECCHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECCCCCCEEE
RFSVKDTGIGIPEAKLDRLFKSFTQVDASTTRKYGGTGLGLAISRQLVELMGGKIGVISH
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEE
EGNGSEFWFTIFLKKQPFYSTIETQPTSAFAGIRALVVDDNAANRKMLKALLSSLDIRVT
CCCCCEEEEEEEEECCCCCHHCCCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHCCEEEE
EASGGDAALGELRSAFKSGDPFALAIIDMQMPDMDGFMLGQTIKEDLLLRNTELFLMSPV
ECCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCC
GTLNQREEYHRAGFSANLSKPVGQLELVAAINKVVFNHDNQSGSRNPSISYPVTEEGEPP
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
MVPVGKLEHYRILLAEDSRVNQMVVIGVLTKFGYGVDVVSNGQECVDVLQKRTYDLVLMD
CCCCCCCCEEEEEEECCCCCCCEEEEEEHHHCCCCCEEECCCHHHHHHHHHCCCEEEEEE
VQMPVMDGLNATGIIRDPASKVLDHNIPVIALTAHAMQGDRESCLYAGMNDYISKPIDAS
ECCHHHCCCCCCEEEECCHHHHHCCCCCEEEEEEHHHCCCHHHHHHCCCHHHHCCCCCHH
VLTETISKWLPVKPDSPA
HHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]