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The map label for this gene is hprK

Identifier: 119356402

GI number: 119356402

Start: 633049

End: 634017

Strand: Direct

Name: hprK

Synonym: Cpha266_0566

Alternate gene names: 119356402

Gene position: 633049-634017 (Clockwise)

Preceding gene: 119356401

Following gene: 119356403

Centisome position: 20.2

GC content: 44.79

Gene sequence:

>969_bases
ATGACTCTGGAACAGAAAGGGCTAAAAAAACAATCCATTACAGTAGCCTACTTTTTTGATACCATCGGCAAGGAGCATGA
TATCAAATTGCGGAGACTGAATAGTGTCGATGAACAGAAACGGCGGATTTTTGAGCGCGATCTGCATCGGCCGGGTCTTG
CTCTTGCTGGATTTACCAATCTCTTTACCTACAAGAGGGTTCAGATTCTTGGTAATACCGAAATGAGATTTTTGAATCAG
CATGAAGAGGATGCAAGAAAAAATGCGTTCGGGAATTTCGTGCGGTTCAAGATTCCCTGTATCATTCTGACAAGCACCAA
CAAGCTTCAGCCTGAGTTGCTGGCAATGGCAACCGAGGCAGGAATACCGGTTTTTTCTACCCGGCATTCGTCAACAAAAA
CAATGTACCTTATTACCGAATTTCTTGACAACCAGTTTTCTCTTTATCAGCAATACCACGGGTCGATGGTTGATGTGTAC
GGAGTTGGCGTGCTGCTTAAAGGCAGGAGCGGACTTGGCAAGTCGGAAGTTGCTCTTGACCTGGTGGAACGAGGGCATGG
TCTTGTCGCTGACGATGTTGTGGTTATTCATCGCAAGGGGGAGTCGATGATACTGACTGCAAAAAGAAATAAAAATATTG
AGCATTTTATGGAAATTCGTGGTCTTGGCGTCGTTGATGTCAAGGCTAATTTCGGTATTCGGGCTATAAGAGATGCCAAG
GAGGTTCAGGTTGTGGTGGAGTTGCTCGAGTGGAACAAGGAGATGGAGTATGAACGGCTCGGCCTTGATACAAAAACAAC
GAAAATTCTCGGGGTCGAAGTCCCTCTTGTTCAGTTGCCGATTTTCCCGGGAAAAAATATTACCGTCATTATTGAGGTGG
TAGCCCTTAATTTCCTTTTAAAGCACTATTACGATTATGTGCCGGCAGAAGCTCTTACAAAGAGAATCAGAACGGCGATA
GATCAATGA

Upstream 100 bases:

>100_bases
AAAGTTTGTTCCCTAATTATATATCAAGACCTGCAGAACGCCATTGGGCCTGTTCTGCAGGGTTGTTCTCGTTTTCTCCT
ATCCACACTATCTCGCGTGT

Downstream 100 bases:

>100_bases
CTCTTCAAAACGATGACCATGTTTACTAAACGGGAAGTAACAGTGCCTGCATGTTCTAATAGCCGGCCATTTCGTTTCTC
GCTGAGCGCGTTAATTCTTT

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTLEQKGLKKQSITVAYFFDTIGKEHDIKLRRLNSVDEQKRRIFERDLHRPGLALAGFTNLFTYKRVQILGNTEMRFLNQ
HEEDARKNAFGNFVRFKIPCIILTSTNKLQPELLAMATEAGIPVFSTRHSSTKTMYLITEFLDNQFSLYQQYHGSMVDVY
GVGVLLKGRSGLGKSEVALDLVERGHGLVADDVVVIHRKGESMILTAKRNKNIEHFMEIRGLGVVDVKANFGIRAIRDAK
EVQVVVELLEWNKEMEYERLGLDTKTTKILGVEVPLVQLPIFPGKNITVIIEVVALNFLLKHYYDYVPAEALTKRIRTAI
DQ

Sequences:

>Translated_322_residues
MTLEQKGLKKQSITVAYFFDTIGKEHDIKLRRLNSVDEQKRRIFERDLHRPGLALAGFTNLFTYKRVQILGNTEMRFLNQ
HEEDARKNAFGNFVRFKIPCIILTSTNKLQPELLAMATEAGIPVFSTRHSSTKTMYLITEFLDNQFSLYQQYHGSMVDVY
GVGVLLKGRSGLGKSEVALDLVERGHGLVADDVVVIHRKGESMILTAKRNKNIEHFMEIRGLGVVDVKANFGIRAIRDAK
EVQVVVELLEWNKEMEYERLGLDTKTTKILGVEVPLVQLPIFPGKNITVIIEVVALNFLLKHYYDYVPAEALTKRIRTAI
DQ
>Mature_321_residues
TLEQKGLKKQSITVAYFFDTIGKEHDIKLRRLNSVDEQKRRIFERDLHRPGLALAGFTNLFTYKRVQILGNTEMRFLNQH
EEDARKNAFGNFVRFKIPCIILTSTNKLQPELLAMATEAGIPVFSTRHSSTKTMYLITEFLDNQFSLYQQYHGSMVDVYG
VGVLLKGRSGLGKSEVALDLVERGHGLVADDVVVIHRKGESMILTAKRNKNIEHFMEIRGLGVVDVKANFGIRAIRDAKE
VQVVVELLEWNKEMEYERLGLDTKTTKILGVEVPLVQLPIFPGKNITVIIEVVALNFLLKHYYDYVPAEALTKRIRTAID
Q

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_CHLPD (A1BDZ5)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911046.1
- ProteinModelPortal:   A1BDZ5
- SMR:   A1BDZ5
- STRING:   A1BDZ5
- GeneID:   4569161
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0566
- NMPDR:   fig|290317.7.peg.594
- eggNOG:   COG1493
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 36737; Mature: 36606

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: ACT_SITE 153-153 ACT_SITE 174-174 ACT_SITE 192-192 ACT_SITE 259-259

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEQKGLKKQSITVAYFFDTIGKEHDIKLRRLNSVDEQKRRIFERDLHRPGLALAGFTN
CCCCHHCCCHHCEEEEEEEHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEHHHHHH
LFTYKRVQILGNTEMRFLNQHEEDARKNAFGNFVRFKIPCIILTSTNKLQPELLAMATEA
HHHEEEEEEECCCHHHHHHCCHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHHHHC
GIPVFSTRHSSTKTMYLITEFLDNQFSLYQQYHGSMVDVYGVGVLLKGRSGLGKSEVALD
CCCEEECCCCCCCEEEEEHHHHCCHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHH
LVERGHGLVADDVVVIHRKGESMILTAKRNKNIEHFMEIRGLGVVDVKANFGIRAIRDAK
HHHCCCCCEECCEEEEEECCCEEEEEECCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHH
EVQVVVELLEWNKEMEYERLGLDTKTTKILGVEVPLVQLPIFPGKNITVIIEVVALNFLL
HHHHHHHHHHCCCCCCHHHHCCCCCCEEEEEEECCEEEECCCCCCCCEEEHHHHHHHHHH
KHYYDYVPAEALTKRIRTAIDQ
HHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLEQKGLKKQSITVAYFFDTIGKEHDIKLRRLNSVDEQKRRIFERDLHRPGLALAGFTN
CCCHHCCCHHCEEEEEEEHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEHHHHHH
LFTYKRVQILGNTEMRFLNQHEEDARKNAFGNFVRFKIPCIILTSTNKLQPELLAMATEA
HHHEEEEEEECCCHHHHHHCCHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHHHHC
GIPVFSTRHSSTKTMYLITEFLDNQFSLYQQYHGSMVDVYGVGVLLKGRSGLGKSEVALD
CCCEEECCCCCCCEEEEEHHHHCCHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHH
LVERGHGLVADDVVVIHRKGESMILTAKRNKNIEHFMEIRGLGVVDVKANFGIRAIRDAK
HHHCCCCCEECCEEEEEECCCEEEEEECCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHH
EVQVVVELLEWNKEMEYERLGLDTKTTKILGVEVPLVQLPIFPGKNITVIIEVVALNFLL
HHHHHHHHHHCCCCCCHHHHCCCCCCEEEEEEECCEEEECCCCCCCCEEEHHHHHHHHHH
KHYYDYVPAEALTKRIRTAIDQ
HHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA