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The map label for this gene is queF

Identifier: 119356397

GI number: 119356397

Start: 629489

End: 629839

Strand: Reverse

Name: queF

Synonym: Cpha266_0561

Alternate gene names: 119356397

Gene position: 629839-629489 (Counterclockwise)

Preceding gene: 119356407

Following gene: 119356395

Centisome position: 20.1

GC content: 44.44

Gene sequence:

>351_bases
ATGAAAAAAGAAATTCTTGAAGTATTCGACAACACCTTTCCCGGAAGGGACTACACCATTGAAATTGTCAACCCGGAATT
CACCTCCGTCTGTCCGATAACAGCGCTTCCTGATTTCGGCACCATCATTATCCGCTATATCCCCGACAAGAGTTGCGTAG
AACTGAAATCACTGAAATACTACTTTCTCGAATTTCGCAACGCGGGCATCTTTTATGAAAACATCACCAACACGATCCTT
GACGATCTTACAAGCGTGCTTCAACCAAGAGAAATGACGGTTATAACCCAATGGAAAGCAAGGGGAGGAATAACAGAAAC
CGTCAGCGTCACCTGGCCTCAAAAGCAGTAA

Upstream 100 bases:

>100_bases
AAAAACAGGCATGAAAATTTACAGAAAGTCAAACGGTATTTCATATTTTGCGTCGAAAGAATATTCGTAATCCCTCAACC
TTTTCAGCACTGCGCATTCA

Downstream 100 bases:

>100_bases
AGGAAAAATCCGGTTCACCCCGATCATCCTCGGCTCGCGAGGAATTTTCCCGAGCGCTCCACCGCAACAAGCCAAAAAAG
CAAAAGCCTCAGCAGAACGC

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MKKEILEVFDNTFPGRDYTIEIVNPEFTSVCPITALPDFGTIIIRYIPDKSCVELKSLKYYFLEFRNAGIFYENITNTIL
DDLTSVLQPREMTVITQWKARGGITETVSVTWPQKQ

Sequences:

>Translated_116_residues
MKKEILEVFDNTFPGRDYTIEIVNPEFTSVCPITALPDFGTIIIRYIPDKSCVELKSLKYYFLEFRNAGIFYENITNTIL
DDLTSVLQPREMTVITQWKARGGITETVSVTWPQKQ
>Mature_116_residues
MKKEILEVFDNTFPGRDYTIEIVNPEFTSVCPITALPDFGTIIIRYIPDKSCVELKSLKYYFLEFRNAGIFYENITNTIL
DDLTSVLQPREMTVITQWKARGGITETVSVTWPQKQ

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEF_CHLPD (A1BDZ0)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911041.1
- ProteinModelPortal:   A1BDZ0
- SMR:   A1BDZ0
- STRING:   A1BDZ0
- GeneID:   4569428
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0561
- NMPDR:   fig|290317.7.peg.589
- eggNOG:   COG0780
- HOGENOM:   HBG294103
- OMA:   FRNAGIF
- ProtClustDB:   PRK13258
- GO:   GO:0005737
- HAMAP:   MF_00818
- InterPro:   IPR016856
- InterPro:   IPR020602
- PIRSF:   PIRSF027377
- TIGRFAMs:   TIGR03139

Pfam domain/function: PF01227 GTP_cyclohydroI

EC number: =1.7.1.13

Molecular weight: Translated: 13417; Mature: 13417

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEILEVFDNTFPGRDYTIEIVNPEFTSVCPITALPDFGTIIIRYIPDKSCVELKSLKY
CCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHE
YFLEFRNAGIFYENITNTILDDLTSVLQPREMTVITQWKARGGITETVSVTWPQKQ
EEEEECCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MKKEILEVFDNTFPGRDYTIEIVNPEFTSVCPITALPDFGTIIIRYIPDKSCVELKSLKY
CCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHE
YFLEFRNAGIFYENITNTILDDLTSVLQPREMTVITQWKARGGITETVSVTWPQKQ
EEEEECCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA