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The map label for this gene is mdtA [H]

Identifier: 119356317

GI number: 119356317

Start: 528519

End: 529610

Strand: Direct

Name: mdtA [H]

Synonym: Cpha266_0480

Alternate gene names: 119356317

Gene position: 528519-529610 (Clockwise)

Preceding gene: 119356314

Following gene: 119356318

Centisome position: 16.86

GC content: 50.46

Gene sequence:

>1092_bases
ATGCAGACTTTACAGAAAGTTCTTCCCAAGTATACTATAGCTCTTGCCCTTGTTTTTTTTGTTACCGTAGCCTATCTCCT
GACCCGTGGCAATACGGTAGACGTTGAGGCTGGTGAGGTTACATATGCCGAACTGGTTCAGGCTATTTATGCCACCGGTT
TTGTCGAGGCGGAAGCCGTGGCCAATCTCAGTTCCGAACTTTCAGGAACGGTGAATTATATCGGCGCTCTTGAGGGCCAG
CAGGTTACCGCCGGCCAGACTATTATTTCGCTTGATAACGCGCAGCCAGGTATCTCGGTTCGTGAGGCGCAGGCGGCTTT
TCTTGAGCAGCAGGCGGTGAATCAGGAGAAAACGATGAAATACAGCCGTGCCAGGAACCTGTTCAGGGAAGGCGCCCTCG
CGCGTCAGGATCTTGATGAAGCCAAAAGGATCAGTTCACAGGCGGAAGAGCTGCTCGAACAGAAGCGCCTGCAATTGAAA
AGCAGGGAGGATGAGCTGAAAAAAATAGCAATAACAGCTCCTTTTGCAGGTGTTCTTACGTTGCAGAGTGTGAAAAAAGG
CGATTATGTTACCGCAAACATGCTTGTCGCAAGGGTTGTTGACACGTCAAAGTATGTGGTGAGCGTTGAGATTGATGAGC
TTGACGTTCCCCGGATTCGTCCCGGACAGGCTGCGGTCGTTGTGCTTGATGCCCTGCCGACTGAACGGTATGATGCCGTT
GTGTCGAGGATTGTGCCTCAGACCGACACCATCACCAAAACATCAAGGGTCTATCTCACGTTTCGGAAGGCCGTAACCGG
TATCCAGGCTGGAATGACCATAACGGCTAATATCGTATACCACATTAAACCGCATACGCTGCTGGTGCGTAAAAGTTCGG
TTTTTGATGATAACCACAAGAGTTATGTCTGGGAAATCGAGAAAGGAAAACTGAAAAAACAGTTGATTGTAACCGGAGCC
AGCGATTTGACCTTTGTTGAGGTTCTCAGTGGTCTTCAGCAAGGCGACAGGGTTGCCCTGCTTCCCGAAGAGCGCTTTCG
AGAGGGAATGGATGCAAACGTTCTGGTCGCAAAAGCCGGGAAGGCGGAGTGA

Upstream 100 bases:

>100_bases
TTTAAAGATTCATAAAATTATGGAAAAACCAAGGTCGGAATAGAGAAAAAGTTCAAAACTCTTAACTTGCAAGACGTGAA
TTTTATAAAGAAAAAGAATC

Downstream 100 bases:

>100_bases
AAAATATATCGATAGAGGTGTTTCAGATAAAGCGCTCTTTTTTTTAGTTCAATGGGTGAGAAAAAAACAATAGCAGTCGT
TCTTGTTGCGCACGGAGAGG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MQTLQKVLPKYTIALALVFFVTVAYLLTRGNTVDVEAGEVTYAELVQAIYATGFVEAEAVANLSSELSGTVNYIGALEGQ
QVTAGQTIISLDNAQPGISVREAQAAFLEQQAVNQEKTMKYSRARNLFREGALARQDLDEAKRISSQAEELLEQKRLQLK
SREDELKKIAITAPFAGVLTLQSVKKGDYVTANMLVARVVDTSKYVVSVEIDELDVPRIRPGQAAVVVLDALPTERYDAV
VSRIVPQTDTITKTSRVYLTFRKAVTGIQAGMTITANIVYHIKPHTLLVRKSSVFDDNHKSYVWEIEKGKLKKQLIVTGA
SDLTFVEVLSGLQQGDRVALLPEERFREGMDANVLVAKAGKAE

Sequences:

>Translated_363_residues
MQTLQKVLPKYTIALALVFFVTVAYLLTRGNTVDVEAGEVTYAELVQAIYATGFVEAEAVANLSSELSGTVNYIGALEGQ
QVTAGQTIISLDNAQPGISVREAQAAFLEQQAVNQEKTMKYSRARNLFREGALARQDLDEAKRISSQAEELLEQKRLQLK
SREDELKKIAITAPFAGVLTLQSVKKGDYVTANMLVARVVDTSKYVVSVEIDELDVPRIRPGQAAVVVLDALPTERYDAV
VSRIVPQTDTITKTSRVYLTFRKAVTGIQAGMTITANIVYHIKPHTLLVRKSSVFDDNHKSYVWEIEKGKLKKQLIVTGA
SDLTFVEVLSGLQQGDRVALLPEERFREGMDANVLVAKAGKAE
>Mature_363_residues
MQTLQKVLPKYTIALALVFFVTVAYLLTRGNTVDVEAGEVTYAELVQAIYATGFVEAEAVANLSSELSGTVNYIGALEGQ
QVTAGQTIISLDNAQPGISVREAQAAFLEQQAVNQEKTMKYSRARNLFREGALARQDLDEAKRISSQAEELLEQKRLQLK
SREDELKKIAITAPFAGVLTLQSVKKGDYVTANMLVARVVDTSKYVVSVEIDELDVPRIRPGQAAVVVLDALPTERYDAV
VSRIVPQTDTITKTSRVYLTFRKAVTGIQAGMTITANIVYHIKPHTLLVRKSSVFDDNHKSYVWEIEKGKLKKQLIVTGA
SDLTFVEVLSGLQQGDRVALLPEERFREGMDANVLVAKAGKAE

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=371, Percent_Identity=24.7978436657682, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082036, Length=323, Percent_Identity=22.2910216718266, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39919; Mature: 39919

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLQKVLPKYTIALALVFFVTVAYLLTRGNTVDVEAGEVTYAELVQAIYATGFVEAEAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHH
ANLSSELSGTVNYIGALEGQQVTAGQTIISLDNAQPGISVREAQAAFLEQQAVNQEKTMK
HHHHHHHCCHHHHHCCCCCCEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHH
YSRARNLFREGALARQDLDEAKRISSQAEELLEQKRLQLKSREDELKKIAITAPFAGVLT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCCHHHHH
LQSVKKGDYVTANMLVARVVDTSKYVVSVEIDELDVPRIRPGQAAVVVLDALPTERYDAV
HHHHCCCCCEEHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHH
VSRIVPQTDTITKTSRVYLTFRKAVTGIQAGMTITANIVYHIKPHTLLVRKSSVFDDNHK
HHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCEEEEEEEEEECCCEEEEEECCCCCCCCC
SYVWEIEKGKLKKQLIVTGASDLTFVEVLSGLQQGDRVALLPEERFREGMDANVLVAKAG
EEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEECCHHHHHCCCCCCEEEECCC
KAE
CCC
>Mature Secondary Structure
MQTLQKVLPKYTIALALVFFVTVAYLLTRGNTVDVEAGEVTYAELVQAIYATGFVEAEAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHH
ANLSSELSGTVNYIGALEGQQVTAGQTIISLDNAQPGISVREAQAAFLEQQAVNQEKTMK
HHHHHHHCCHHHHHCCCCCCEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHH
YSRARNLFREGALARQDLDEAKRISSQAEELLEQKRLQLKSREDELKKIAITAPFAGVLT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCCHHHHH
LQSVKKGDYVTANMLVARVVDTSKYVVSVEIDELDVPRIRPGQAAVVVLDALPTERYDAV
HHHHCCCCCEEHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHH
VSRIVPQTDTITKTSRVYLTFRKAVTGIQAGMTITANIVYHIKPHTLLVRKSSVFDDNHK
HHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCEEEEEEEEEECCCEEEEEECCCCCCCCC
SYVWEIEKGKLKKQLIVTGASDLTFVEVLSGLQQGDRVALLPEERFREGMDANVLVAKAG
EEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEECCHHHHHCCCCCCEEEECCC
KAE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA