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The map label for this gene is arsB [H]

Identifier: 119356304

GI number: 119356304

Start: 514430

End: 515491

Strand: Direct

Name: arsB [H]

Synonym: Cpha266_0466

Alternate gene names: 119356304

Gene position: 514430-515491 (Clockwise)

Preceding gene: 119356303

Following gene: 119356305

Centisome position: 16.41

GC content: 49.44

Gene sequence:

>1062_bases
ATGGGTATGTCAACAAAACAGCTCTCGTTTCTTGATCGCTATCTGACGCTCTGGATCTTTCTTGCCATGGGCATTGGTGT
GCTCTGGGGTTATCTGTTTCCCGGCATTGCCGGATTCTGGAACCATTTTCAGCGCGGCACCACCAATATTCCCATTGCCA
TTGGGCTGATCGTTATGATGTATCCGCCGTTGGCGAAGGTTAAATATGAGGAACTGGGCGATGTGTTTCGTAATACGAGG
GTACTGGGGCTCTCGCTGCTGCAGAACTGGGTTGTAGGGCCGCTGCTGATGTTCGTGCTTGCTGTTATATTTCTTTCCGA
TATGCCGCACTATATGGCAGGTCTTATCATGATCGGTCTTGCCCGGTGTATTGCCATGGTGATTGTCTGGAACGAGCTTG
CCAAAGGGGATACGGAGTATGCTGCAGGGCTTGTTGCCTTCAACTCGATCTTTCAGGTGCTTTTTTTCTCCCTCTATGCA
TGGGTTTTTCTCACCGTTCTGCCGGAGTGGCTTGGAATGACGACCGTAGCCGTTGATATTACCATTGGTGAAATTGCAGG
CTCCGTGTTTATCTACCTCGGCATTCCCTTTATTGCAGGGTTTCTGACCCGTTTTTTTCTATTGCGTCTGAAAGGACGCG
AGTGGTATGAGGGTGAATTTATTCCCCGCATCAGCCCGCTCACCCTCATATCGCTGCTTTTCACCATTGTGGTGATGTTT
TCACTCAAAGGTGAGTATATCGTTACCATACCCATGGATGTCGTGCGCATCGCCATACCGCTGCTCATTTATTTCGTGAT
CATGTTTCTTCTCTCGTTTTACATGGCAAGAAAGGCCGGAGCCGATTACCCGAAAACTGCCACGCTCTCCTTTACAGCCG
CAAGTAATAATTTTGAGCTTGCTATTGCTGTGGCGGTTTCGGTATTCGGTATCAATTCGGGAGAGGCATTTGCCGCCGTT
ATCGGTCCGCTGGTTGAGGTTCCCGCATTGATTGCGCTCGTCAATGTTTCACTCTGGTTCAGGGGCAGATTTTTCGCAAC
GCAGGAGAGCGGTTTTCAATGA

Upstream 100 bases:

>100_bases
AGCAGGGAGGAGCAGCTTGACGTGTTCAGGCGTGTCCGCGACGAGATCAATACCCGGTTCAGGCAATTTTATAACGAAAC
GGAAAAAGGAGAATAGCGCA

Downstream 100 bases:

>100_bases
GCTCTTCTTGTGCGGAGATTGATTTTCGGTAAGGGTGTGAAAAAATTTGCAAAAATTGCGAAGTATTTTTATATAACCAT
ATCGTTATATAGGGTTATGT

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MGMSTKQLSFLDRYLTLWIFLAMGIGVLWGYLFPGIAGFWNHFQRGTTNIPIAIGLIVMMYPPLAKVKYEELGDVFRNTR
VLGLSLLQNWVVGPLLMFVLAVIFLSDMPHYMAGLIMIGLARCIAMVIVWNELAKGDTEYAAGLVAFNSIFQVLFFSLYA
WVFLTVLPEWLGMTTVAVDITIGEIAGSVFIYLGIPFIAGFLTRFFLLRLKGREWYEGEFIPRISPLTLISLLFTIVVMF
SLKGEYIVTIPMDVVRIAIPLLIYFVIMFLLSFYMARKAGADYPKTATLSFTAASNNFELAIAVAVSVFGINSGEAFAAV
IGPLVEVPALIALVNVSLWFRGRFFATQESGFQ

Sequences:

>Translated_353_residues
MGMSTKQLSFLDRYLTLWIFLAMGIGVLWGYLFPGIAGFWNHFQRGTTNIPIAIGLIVMMYPPLAKVKYEELGDVFRNTR
VLGLSLLQNWVVGPLLMFVLAVIFLSDMPHYMAGLIMIGLARCIAMVIVWNELAKGDTEYAAGLVAFNSIFQVLFFSLYA
WVFLTVLPEWLGMTTVAVDITIGEIAGSVFIYLGIPFIAGFLTRFFLLRLKGREWYEGEFIPRISPLTLISLLFTIVVMF
SLKGEYIVTIPMDVVRIAIPLLIYFVIMFLLSFYMARKAGADYPKTATLSFTAASNNFELAIAVAVSVFGINSGEAFAAV
IGPLVEVPALIALVNVSLWFRGRFFATQESGFQ
>Mature_352_residues
GMSTKQLSFLDRYLTLWIFLAMGIGVLWGYLFPGIAGFWNHFQRGTTNIPIAIGLIVMMYPPLAKVKYEELGDVFRNTRV
LGLSLLQNWVVGPLLMFVLAVIFLSDMPHYMAGLIMIGLARCIAMVIVWNELAKGDTEYAAGLVAFNSIFQVLFFSLYAW
VFLTVLPEWLGMTTVAVDITIGEIAGSVFIYLGIPFIAGFLTRFFLLRLKGREWYEGEFIPRISPLTLISLLFTIVVMFS
LKGEYIVTIPMDVVRIAIPLLIYFVIMFLLSFYMARKAGADYPKTATLSFTAASNNFELAIAVAVSVFGINSGEAFAAVI
GPLVEVPALIALVNVSLWFRGRFFATQESGFQ

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=316, Percent_Identity=35.4430379746835, Blast_Score=170, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 39361; Mature: 39229

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
>Mature Secondary Structure 
GMSTKQLSFLDRYLTLWIFLAMGIGVLWGYLFPGIAGFWNHFQRGTTNIPIAIGLIVMM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
YPPLAKVKYEELGDVFRNTRVLGLSLLQNWVVGPLLMFVLAVIFLSDMPHYMAGLIMIGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ARCIAMVIVWNELAKGDTEYAAGLVAFNSIFQVLFFSLYAWVFLTVLPEWLGMTTVAVDI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
TIGEIAGSVFIYLGIPFIAGFLTRFFLLRLKGREWYEGEFIPRISPLTLISLLFTIVVMF
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SLKGEYIVTIPMDVVRIAIPLLIYFVIMFLLSFYMARKAGADYPKTATLSFTAASNNFEL
HCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEE
AIAVAVSVFGINSGEAFAAVIGPLVEVPALIALVNVSLWFRGRFFATQESGFQ
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]