Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 119356258

GI number: 119356258

Start: 464415

End: 465641

Strand: Direct

Name: mrdB [H]

Synonym: Cpha266_0420

Alternate gene names: 119356258

Gene position: 464415-465641 (Clockwise)

Preceding gene: 119356256

Following gene: 119356260

Centisome position: 14.82

GC content: 41.65

Gene sequence:

>1227_bases
ATGACTGATAAACAAAGTAATGTGGATTTTTGGCTTCTTGTTCCGATGATTGGACTCATTGTATTCGGACTGATGGCTAT
TTTCAGTGCAACACATGGCGCAGGTGAAACAACGCTGTTTTATCGGCAGTTTGCCTGGGGAGTTATTGGAGCTGTTGTCA
TGCTCTTTGTCTATTTCAATGATTATCGTGTTATTCGCGATAACGCCTATCTGTTATATCTTATCTCCATATTTCTTCTT
GTTGTCGTACTGCTTTTCGGAACGAAAATTGCCGGACAGACAAGTTGGGTAAAAATAGGCTTTTTCAGTTTTCAGCCCTC
TGAAATAGCGAAAATGGCGACTATTCTTGCGCTTGCACGCTTTCTCTCGGATGATGAAACGGATATTACGTTTACCCCTC
ATCTTCTTATTGCGCTTGGCATTCCGCTTTTTCCGGCTCTGCTCATTATGCTCCAGCCTGATATGGGCACTACGCTGACG
AGCCTCTCCTTTATTATTCCGATGTTTATCATGTCCGGCTTTGACCTGTACATAGTCATACCGTATCTCTTGCCGATCAT
TCTCATGCTCAGCGGTTTTTTTAATGTGTTTTATATCGTTGGTCTTGCTGTACTGTTGTTTCTTGCACTCTGGCTCCAGA
AGAAAAAATTCAAAATGCATCAGCTTCTTGTTACAGCGGCAGGGCTCGGAGCAGCACTTTTTACTAACCGGTTTGCCGCT
GAATTGCTCAAGCCGCATCAGTTAAAGAGAATCCAGACCTTTCTTGATCCTATGTCGGATCCTCGGGGCGCCGGTTATAA
TGTAATCCAGGCTAAAATAGCTATCAGTTCGGGAGGCTTTTTTGGTAAAGGTTATCTTGAGGGTACACAGACACAACTTC
GTTTTATCCCGGCTCAATGGACGGACTTTATTTTCTGTGTTATTGCTGAAGAACTTGGTTTTGTTGGTTCTTTTGTTCTG
TTGCTATTATTTCTTGTACTCATACTGAGGCTGTTGTGGATCATATCCTCAATAAAAAATAAATTCGTCGAACTTACTCT
GGCTGGTTTTGTTTCACTATTGTTGATTCATGTTATTATCAATATTGGTATGACGATAGGTCTTATTCCCGTAATCGGTG
TGCCGCTGCCTTTTGTTTCCTATGGTGGTTCTTCATTGCTTGGCAATATGATCATGGTGGCTCTTGCGTTGAATTTTGTG
CACAATAAAAGAAGTATAGGTTATTAA

Upstream 100 bases:

>100_bases
TAACGGGATAAAAAGAGCATAAGGAACGTTCCTGTAGCATAAGGTACGTTTCTATACTAATGATTCCTTCTTGATAATGA
AAATGAGATTCTTGTGAATT

Downstream 100 bases:

>100_bases
TAATCAGTATGTTAGCGTTTCAGATCAAACCAGTTGTCCCTGTATGCCTTTTATAAGGATCATTTTTTCCCTGCAATAAA
AAAGCGCATTTTCATGCGCT

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTDKQSNVDFWLLVPMIGLIVFGLMAIFSATHGAGETTLFYRQFAWGVIGAVVMLFVYFNDYRVIRDNAYLLYLISIFLL
VVVLLFGTKIAGQTSWVKIGFFSFQPSEIAKMATILALARFLSDDETDITFTPHLLIALGIPLFPALLIMLQPDMGTTLT
SLSFIIPMFIMSGFDLYIVIPYLLPIILMLSGFFNVFYIVGLAVLLFLALWLQKKKFKMHQLLVTAAGLGAALFTNRFAA
ELLKPHQLKRIQTFLDPMSDPRGAGYNVIQAKIAISSGGFFGKGYLEGTQTQLRFIPAQWTDFIFCVIAEELGFVGSFVL
LLLFLVLILRLLWIISSIKNKFVELTLAGFVSLLLIHVIINIGMTIGLIPVIGVPLPFVSYGGSSLLGNMIMVALALNFV
HNKRSIGY

Sequences:

>Translated_408_residues
MTDKQSNVDFWLLVPMIGLIVFGLMAIFSATHGAGETTLFYRQFAWGVIGAVVMLFVYFNDYRVIRDNAYLLYLISIFLL
VVVLLFGTKIAGQTSWVKIGFFSFQPSEIAKMATILALARFLSDDETDITFTPHLLIALGIPLFPALLIMLQPDMGTTLT
SLSFIIPMFIMSGFDLYIVIPYLLPIILMLSGFFNVFYIVGLAVLLFLALWLQKKKFKMHQLLVTAAGLGAALFTNRFAA
ELLKPHQLKRIQTFLDPMSDPRGAGYNVIQAKIAISSGGFFGKGYLEGTQTQLRFIPAQWTDFIFCVIAEELGFVGSFVL
LLLFLVLILRLLWIISSIKNKFVELTLAGFVSLLLIHVIINIGMTIGLIPVIGVPLPFVSYGGSSLLGNMIMVALALNFV
HNKRSIGY
>Mature_407_residues
TDKQSNVDFWLLVPMIGLIVFGLMAIFSATHGAGETTLFYRQFAWGVIGAVVMLFVYFNDYRVIRDNAYLLYLISIFLLV
VVLLFGTKIAGQTSWVKIGFFSFQPSEIAKMATILALARFLSDDETDITFTPHLLIALGIPLFPALLIMLQPDMGTTLTS
LSFIIPMFIMSGFDLYIVIPYLLPIILMLSGFFNVFYIVGLAVLLFLALWLQKKKFKMHQLLVTAAGLGAALFTNRFAAE
LLKPHQLKRIQTFLDPMSDPRGAGYNVIQAKIAISSGGFFGKGYLEGTQTQLRFIPAQWTDFIFCVIAEELGFVGSFVLL
LLFLVLILRLLWIISSIKNKFVELTLAGFVSLLLIHVIINIGMTIGLIPVIGVPLPFVSYGGSSLLGNMIMVALALNFVH
NKRSIGY

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=418, Percent_Identity=36.3636363636364, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI1786277, Length=338, Percent_Identity=27.5147928994083, Blast_Score=121, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45358; Mature: 45227

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKQSNVDFWLLVPMIGLIVFGLMAIFSATHGAGETTLFYRQFAWGVIGAVVMLFVYFN
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
DYRVIRDNAYLLYLISIFLLVVVLLFGTKIAGQTSWVKIGFFSFQPSEIAKMATILALAR
CEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHH
FLSDDETDITFTPHLLIALGIPLFPALLIMLQPDMGTTLTSLSFIIPMFIMSGFDLYIVI
HHCCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
PYLLPIILMLSGFFNVFYIVGLAVLLFLALWLQKKKFKMHQLLVTAAGLGAALFTNRFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLKPHQLKRIQTFLDPMSDPRGAGYNVIQAKIAISSGGFFGKGYLEGTQTQLRFIPAQW
HHHCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCEECCCCCCCCHHHEEECCHH
TDFIFCVIAEELGFVGSFVLLLLFLVLILRLLWIISSIKNKFVELTLAGFVSLLLIHVII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGMTIGLIPVIGVPLPFVSYGGSSLLGNMIMVALALNFVHNKRSIGY
HHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDKQSNVDFWLLVPMIGLIVFGLMAIFSATHGAGETTLFYRQFAWGVIGAVVMLFVYFN
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
DYRVIRDNAYLLYLISIFLLVVVLLFGTKIAGQTSWVKIGFFSFQPSEIAKMATILALAR
CEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHH
FLSDDETDITFTPHLLIALGIPLFPALLIMLQPDMGTTLTSLSFIIPMFIMSGFDLYIVI
HHCCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
PYLLPIILMLSGFFNVFYIVGLAVLLFLALWLQKKKFKMHQLLVTAAGLGAALFTNRFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLKPHQLKRIQTFLDPMSDPRGAGYNVIQAKIAISSGGFFGKGYLEGTQTQLRFIPAQW
HHHCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCEECCCCCCCCHHHEEECCHH
TDFIFCVIAEELGFVGSFVLLLLFLVLILRLLWIISSIKNKFVELTLAGFVSLLLIHVII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGMTIGLIPVIGVPLPFVSYGGSSLLGNMIMVALALNFVHNKRSIGY
HHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]