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The map label for this gene is sucD [H]

Identifier: 119356239

GI number: 119356239

Start: 444915

End: 445814

Strand: Direct

Name: sucD [H]

Synonym: Cpha266_0400

Alternate gene names: 119356239

Gene position: 444915-445814 (Clockwise)

Preceding gene: 119356238

Following gene: 119356241

Centisome position: 14.2

GC content: 51.22

Gene sequence:

>900_bases
ATGAGTGTTTTAGTCAATAAGGATACCCGCCTTGTTGTACAGGGTATAACAGGTGGCGAAGGAACCTTTCATACTTCCCA
GATCCTTGAATACGGAACCAATGTGGTCGCCGGCGTAACGCCCGGAAAAGGGGGTACAATTTATCATGGCAATGAACGGG
ATCATTTCTGTCGTCCGGTTCCGGTGTTCAATACGGTGAAGGACGCCGTGGATAAGGCGGAGGCCAATGCGACGGTTATT
TTTGTTCCGGCACCCTTTGCTGCGGATGCGATCATGGAGGCAGCAGATGCGGGCCTGAAGGTCATTATCTGCATTACGGA
AGGAATTCCTGTCAACGACATGATGAAGGCGTATGCTTTCGTCAAGGAAAAAGGTGCTGTGCTTGTCGGTCCAAACTGTC
CCGGAGTTATTACTCCCGGCGAGGCAAAAGTTGGTATCATGCCGGGCTTTATTCACATGAAAGGCACGATTGGCGTTGTG
TCACGCAGCGGAACCCTGACCTATGAAGCTGTTCATCAGCTTACCGCAGTAGGGCTTGGACAGTCAACCTGCATAGGTAT
TGGCGGTGATCCCATTATCGGCACCCGATTTATTGATGCCATAAAGCTTTTTGCAAAGGATGATGAAACCGAAGGTCTGG
TGATGATCGGCGAAATCGGTGGCAGCGCTGAAGAGGAGGCCGCGGAGTATATCAAGAGATATTTTAAAAAACCGGTAGTC
GGGTTTATAGCGGGACGAACAGCGCCTCCCGGCAGGCGGATGGGACATGCCGGCGCTATCGTTTCAGGAGGAAAGGGAAC
AGCAGAAGACAAGATCCATGCTATGGAGGCTGCCGGTATTCATATGGTCGATAATCCTGGCGATATCGGTACCGCAATGC
TTAAGGCTCTGGGACGATAG

Upstream 100 bases:

>100_bases
TTTGAGGAAGGAAAATTGCTTGGTATTGCCGGACTTATGCAGCATTCTATCGTTTAAGAAAAGAGGTGATTTGGTAAACC
ATTAATAAACAAGCAGGATT

Downstream 100 bases:

>100_bases
CCGAGTTGTGAGTTACAGTTACAGAACTTTTTCGATCGATGAAAACGACAACTTCTTTAGCTGTAACTCACCTTGCCCGG
GCAGCTACAGCCCGAGGGAA

Product: succinyl-CoA synthetase (ADP-forming) alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSVLVNKDTRLVVQGITGGEGTFHTSQILEYGTNVVAGVTPGKGGTIYHGNERDHFCRPVPVFNTVKDAVDKAEANATVI
FVPAPFAADAIMEAADAGLKVIICITEGIPVNDMMKAYAFVKEKGAVLVGPNCPGVITPGEAKVGIMPGFIHMKGTIGVV
SRSGTLTYEAVHQLTAVGLGQSTCIGIGGDPIIGTRFIDAIKLFAKDDETEGLVMIGEIGGSAEEEAAEYIKRYFKKPVV
GFIAGRTAPPGRRMGHAGAIVSGGKGTAEDKIHAMEAAGIHMVDNPGDIGTAMLKALGR

Sequences:

>Translated_299_residues
MSVLVNKDTRLVVQGITGGEGTFHTSQILEYGTNVVAGVTPGKGGTIYHGNERDHFCRPVPVFNTVKDAVDKAEANATVI
FVPAPFAADAIMEAADAGLKVIICITEGIPVNDMMKAYAFVKEKGAVLVGPNCPGVITPGEAKVGIMPGFIHMKGTIGVV
SRSGTLTYEAVHQLTAVGLGQSTCIGIGGDPIIGTRFIDAIKLFAKDDETEGLVMIGEIGGSAEEEAAEYIKRYFKKPVV
GFIAGRTAPPGRRMGHAGAIVSGGKGTAEDKIHAMEAAGIHMVDNPGDIGTAMLKALGR
>Mature_298_residues
SVLVNKDTRLVVQGITGGEGTFHTSQILEYGTNVVAGVTPGKGGTIYHGNERDHFCRPVPVFNTVKDAVDKAEANATVIF
VPAPFAADAIMEAADAGLKVIICITEGIPVNDMMKAYAFVKEKGAVLVGPNCPGVITPGEAKVGIMPGFIHMKGTIGVVS
RSGTLTYEAVHQLTAVGLGQSTCIGIGGDPIIGTRFIDAIKLFAKDDETEGLVMIGEIGGSAEEEAAEYIKRYFKKPVVG
FIAGRTAPPGRRMGHAGAIVSGGKGTAEDKIHAMEAAGIHMVDNPGDIGTAMLKALGR

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=300, Percent_Identity=56.3333333333333, Blast_Score=288, Evalue=3e-78,
Organism=Homo sapiens, GI38569423, Length=245, Percent_Identity=29.3877551020408, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38569421, Length=245, Percent_Identity=29.3877551020408, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1786949, Length=297, Percent_Identity=59.9326599326599, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1786513, Length=293, Percent_Identity=26.2798634812287, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17553126, Length=301, Percent_Identity=56.1461794019934, Blast_Score=317, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI17550194, Length=301, Percent_Identity=55.8139534883721, Blast_Score=316, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17557344, Length=280, Percent_Identity=27.8571428571429, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17551266, Length=309, Percent_Identity=26.2135922330097, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324716, Length=307, Percent_Identity=48.2084690553746, Blast_Score=268, Evalue=7e-73,
Organism=Drosophila melanogaster, GI21356559, Length=303, Percent_Identity=54.1254125412541, Blast_Score=332, Evalue=1e-91,
Organism=Drosophila melanogaster, GI28574296, Length=303, Percent_Identity=54.7854785478548, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI281363477, Length=273, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281363475, Length=273, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281363473, Length=273, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31075; Mature: 30944

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2 ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVNKDTRLVVQGITGGEGTFHTSQILEYGTNVVAGVTPGKGGTIYHGNERDHFCRPV
CCEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCCCCC
PVFNTVKDAVDKAEANATVIFVPAPFAADAIMEAADAGLKVIICITEGIPVNDMMKAYAF
CHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHH
VKEKGAVLVGPNCPGVITPGEAKVGIMPGFIHMKGTIGVVSRSGTLTYEAVHQLTAVGLG
HHHCCCEEECCCCCCEECCCCCEEEECCCEEEECCEEEEEECCCCCHHHHHHHHHHHCCC
QSTCIGIGGDPIIGTRFIDAIKLFAKDDETEGLVMIGEIGGSAEEEAAEYIKRYFKKPVV
CCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCE
GFIAGRTAPPGRRMGHAGAIVSGGKGTAEDKIHAMEAAGIHMVDNPGDIGTAMLKALGR
EEEECCCCCCCCCCCCCCCEEECCCCCCHHHHEEEHHCCEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SVLVNKDTRLVVQGITGGEGTFHTSQILEYGTNVVAGVTPGKGGTIYHGNERDHFCRPV
CEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCCCCC
PVFNTVKDAVDKAEANATVIFVPAPFAADAIMEAADAGLKVIICITEGIPVNDMMKAYAF
CHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHH
VKEKGAVLVGPNCPGVITPGEAKVGIMPGFIHMKGTIGVVSRSGTLTYEAVHQLTAVGLG
HHHCCCEEECCCCCCEECCCCCEEEECCCEEEECCEEEEEECCCCCHHHHHHHHHHHCCC
QSTCIGIGGDPIIGTRFIDAIKLFAKDDETEGLVMIGEIGGSAEEEAAEYIKRYFKKPVV
CCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCE
GFIAGRTAPPGRRMGHAGAIVSGGKGTAEDKIHAMEAAGIHMVDNPGDIGTAMLKALGR
EEEECCCCCCCCCCCCCCCEEECCCCCCHHHHEEEHHCCEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]