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The map label for this gene is ruvA

Identifier: 119356229

GI number: 119356229

Start: 431842

End: 432444

Strand: Direct

Name: ruvA

Synonym: Cpha266_0390

Alternate gene names: 119356229

Gene position: 431842-432444 (Clockwise)

Preceding gene: 119356228

Following gene: 119356230

Centisome position: 13.78

GC content: 49.25

Gene sequence:

>603_bases
ATGTTTGCATATTTTAAGGGCAGCCTGGTTACAGCGCTGCCGGAAGAAGCGGTTATTGACGTTTCCGGTGTTGCTTACCG
GATGCTCATTTCTGCGACCACCTTTCGCCAACTGCCCGATGAGGGCAGTCAGGTTCTTCTTTATGCCCACCTTTCCGTCA
GGGAAGATGCCTTGCAGCTTTACGGATTTTTCAAAGAAGAGGAACGGCAGTTGTTTCGATTGCTTTTGCTGACATCCGGT
GTTGGCCCAAAACTTGCTCTTGCTGTGCTTTCCGGTCTTCAGGTTCCCGAAGTCCATGAGGCGATCATGGCTAACGAACC
CGAAAGACTGTATGGTGTCAGCGGGGTCGGCAAGAAAACGGCAGCAAGAATCATTCTTGAACTGAGAGATAAAATCCTTA
AGCTTCCGCTGGTTACGCCGGCAGCAGGAAAAGCAGCAATGCCTTCCCATCATGTTAAGGATGATGCTGTTCATGCCCTT
GTGACCCTCGGTTTTTCAAGACTCCTTGCACAAAAAGCCGTTTCGGCTCTTCTTGAAGAGAAGCCGGAACAATCCGTTGA
AGAGGTCATTAAGTATGCACTCGCGACCATTCATAACAGTTAA

Upstream 100 bases:

>100_bases
AGTGTCATTTTTTCTCATTCATTCCAGGTTTTTTTTTGGTCTGATAGTTTCATGAACCGGCATTACAGCGGTTTTCCGTC
CGGTCAGCCTTATTCCTCTC

Downstream 100 bases:

>100_bases
CCCCGATTTTCGGTGAATTACCAGGAAGCACTTGATTTTCTCTATCCTCTGCACCGTTTCGGTATCAAGCCCGGTCTTGA
AAGGGTTTTCGGTCTGCTTG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MFAYFKGSLVTALPEEAVIDVSGVAYRMLISATTFRQLPDEGSQVLLYAHLSVREDALQLYGFFKEEERQLFRLLLLTSG
VGPKLALAVLSGLQVPEVHEAIMANEPERLYGVSGVGKKTAARIILELRDKILKLPLVTPAAGKAAMPSHHVKDDAVHAL
VTLGFSRLLAQKAVSALLEEKPEQSVEEVIKYALATIHNS

Sequences:

>Translated_200_residues
MFAYFKGSLVTALPEEAVIDVSGVAYRMLISATTFRQLPDEGSQVLLYAHLSVREDALQLYGFFKEEERQLFRLLLLTSG
VGPKLALAVLSGLQVPEVHEAIMANEPERLYGVSGVGKKTAARIILELRDKILKLPLVTPAAGKAAMPSHHVKDDAVHAL
VTLGFSRLLAQKAVSALLEEKPEQSVEEVIKYALATIHNS
>Mature_200_residues
MFAYFKGSLVTALPEEAVIDVSGVAYRMLISATTFRQLPDEGSQVLLYAHLSVREDALQLYGFFKEEERQLFRLLLLTSG
VGPKLALAVLSGLQVPEVHEAIMANEPERLYGVSGVGKKTAARIILELRDKILKLPLVTPAAGKAAMPSHHVKDDAVHAL
VTLGFSRLLAQKAVSALLEEKPEQSVEEVIKYALATIHNS

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=38.3084577114428, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_CHLPD (A1BDH2)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_910873.1
- ProteinModelPortal:   A1BDH2
- SMR:   A1BDH2
- STRING:   A1BDH2
- GeneID:   4568983
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0390
- NMPDR:   fig|290317.7.peg.399
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21832; Mature: 21832

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAYFKGSLVTALPEEAVIDVSGVAYRMLISATTFRQLPDEGSQVLLYAHLSVREDALQL
CCEEECCCHHHHCCCHHEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHH
YGFFKEEERQLFRLLLLTSGVGPKLALAVLSGLQVPEVHEAIMANEPERLYGVSGVGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCCHHHHCCCCCCHHH
AARIILELRDKILKLPLVTPAAGKAAMPSHHVKDDAVHALVTLGFSRLLAQKAVSALLEE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KPEQSVEEVIKYALATIHNS
CCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFAYFKGSLVTALPEEAVIDVSGVAYRMLISATTFRQLPDEGSQVLLYAHLSVREDALQL
CCEEECCCHHHHCCCHHEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHH
YGFFKEEERQLFRLLLLTSGVGPKLALAVLSGLQVPEVHEAIMANEPERLYGVSGVGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCCHHHHCCCCCCHHH
AARIILELRDKILKLPLVTPAAGKAAMPSHHVKDDAVHALVTLGFSRLLAQKAVSALLEE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KPEQSVEEVIKYALATIHNS
CCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA