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The map label for this gene is ykcC [H]

Identifier: 119356189

GI number: 119356189

Start: 386658

End: 387659

Strand: Reverse

Name: ykcC [H]

Synonym: Cpha266_0350

Alternate gene names: 119356189

Gene position: 387659-386658 (Counterclockwise)

Preceding gene: 119356190

Following gene: 119356188

Centisome position: 12.37

GC content: 38.42

Gene sequence:

>1002_bases
ATGCAATTATTGTCATTAGTTATTCCTTGCTACAACGAGGAAGCAGTGATTGATGAAACTATTAAACGACTTAAAACTTT
CTGTTCAGAACGTAATGACCTTGATGTTGAGCTCATTCTTGTTGATGATGGCAGTCGGGACAGGACAAGAATGCTTCTGA
AATCATATGCTTCAGATGACACCAGAATAAAAGTCATTGTCTTTGCAAGAAATTTCGGTCATCAAATTGCTGTTACAGCA
GGAATCGATGCTGCTCGTGGTGATGCAGTTGTTCTCATTGATGCAGATCTACAGGATCCTCCTGAAGTGATTCATAAAAT
GATTGCAAAATGGCGAGAAGGTTATGATGTTATTTATGGAACTCGTGCCGTCAGAATAGGCGAATCAGCATTTAAACAGT
TTTCAGCTCGTTTTTTTTACAGATTTTTAAATAAACTTTCTGATATTCCTATCCCTTTAGACACTGGTGATTTCAGACTG
ATGAGCAGAGATGTTGTTGACACACTGAAAGCTATGCCTGAAAATGATCGTTTTGTCAGGGGTATGGTCAGTTGGGTGGG
CTTTAAACAGACCGCCCTTCCATATACCAGACAAGAGAGATTTGCCGGTGAAAGCAAATATCCATTAAAGAAAATGCTTC
GTTTTGCAAACGACGGCATTTTATCATTTTCAACAAAACCACTTCAGATCTCAATTAGCTTGGGATTATTATCTGCCGCA
CTTGCTTTTGCAGGGATTATCTATGCATTACTTGTAAGAATCTTTACCTATAACTGGGTAGAAGGTTGGGCTGGTATCAT
GATTGCTGTTCTTTTTCTGGGCGGAATACAGCTTATCAGTGTTGGAATTCTAGGGGAATATATTGGGAGAATATATAATG
AAGTTAAAAAACGACCATTGTATGTTGTAGAAGAGTACGTAGGTTTTAACTCCGAAGATCTTAAAATGAGTCGCAGTCCT
GTTATCAGACACTTCTCGTATCATGATAACCATATCAAGTGA

Upstream 100 bases:

>100_bases
ATGATTACACTAATAGTGAGTACTCAATTACAAAAGGAATAAGCAGAATAAGCAATTTAATTCACGCTTTAAATTAGTCA
TATCTTCTGGAGTTCATAAA

Downstream 100 bases:

>100_bases
AATAATCAGGTATTTGATTACAGGAATTTTTAACACACTTGTTGGTTATGGAACTTTTTTCGTTTTCTATCGTTTTGTAA
ATCTCAGCCCTGAACTATCT

Product: glycosyl transferase family protein

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MQLLSLVIPCYNEEAVIDETIKRLKTFCSERNDLDVELILVDDGSRDRTRMLLKSYASDDTRIKVIVFARNFGHQIAVTA
GIDAARGDAVVLIDADLQDPPEVIHKMIAKWREGYDVIYGTRAVRIGESAFKQFSARFFYRFLNKLSDIPIPLDTGDFRL
MSRDVVDTLKAMPENDRFVRGMVSWVGFKQTALPYTRQERFAGESKYPLKKMLRFANDGILSFSTKPLQISISLGLLSAA
LAFAGIIYALLVRIFTYNWVEGWAGIMIAVLFLGGIQLISVGILGEYIGRIYNEVKKRPLYVVEEYVGFNSEDLKMSRSP
VIRHFSYHDNHIK

Sequences:

>Translated_333_residues
MQLLSLVIPCYNEEAVIDETIKRLKTFCSERNDLDVELILVDDGSRDRTRMLLKSYASDDTRIKVIVFARNFGHQIAVTA
GIDAARGDAVVLIDADLQDPPEVIHKMIAKWREGYDVIYGTRAVRIGESAFKQFSARFFYRFLNKLSDIPIPLDTGDFRL
MSRDVVDTLKAMPENDRFVRGMVSWVGFKQTALPYTRQERFAGESKYPLKKMLRFANDGILSFSTKPLQISISLGLLSAA
LAFAGIIYALLVRIFTYNWVEGWAGIMIAVLFLGGIQLISVGILGEYIGRIYNEVKKRPLYVVEEYVGFNSEDLKMSRSP
VIRHFSYHDNHIK
>Mature_333_residues
MQLLSLVIPCYNEEAVIDETIKRLKTFCSERNDLDVELILVDDGSRDRTRMLLKSYASDDTRIKVIVFARNFGHQIAVTA
GIDAARGDAVVLIDADLQDPPEVIHKMIAKWREGYDVIYGTRAVRIGESAFKQFSARFFYRFLNKLSDIPIPLDTGDFRL
MSRDVVDTLKAMPENDRFVRGMVSWVGFKQTALPYTRQERFAGESKYPLKKMLRFANDGILSFSTKPLQISISLGLLSAA
LAFAGIIYALLVRIFTYNWVEGWAGIMIAVLFLGGIQLISVGILGEYIGRIYNEVKKRPLYVVEEYVGFNSEDLKMSRSP
VIRHFSYHDNHIK

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=235, Percent_Identity=29.7872340425532, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1788692, Length=301, Percent_Identity=43.5215946843854, Blast_Score=258, Evalue=4e-70,
Organism=Escherichia coli, GI1788588, Length=320, Percent_Identity=33.125, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1787259, Length=93, Percent_Identity=38.7096774193548, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71999402, Length=232, Percent_Identity=30.6034482758621, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24585265, Length=241, Percent_Identity=31.5352697095436, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 37915; Mature: 37915

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLSLVIPCYNEEAVIDETIKRLKTFCSERNDLDVELILVDDGSRDRTRMLLKSYASDD
CCHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCC
TRIKVIVFARNFGHQIAVTAGIDAARGDAVVLIDADLQDPPEVIHKMIAKWREGYDVIYG
CEEEEEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEC
TRAVRIGESAFKQFSARFFYRFLNKLSDIPIPLDTGDFRLMSRDVVDTLKAMPENDRFVR
CEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
GMVSWVGFKQTALPYTRQERFAGESKYPLKKMLRFANDGILSFSTKPLQISISLGLLSAA
HHHHHHCCHHHCCCCHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCEEEEEHHHHHHHH
LAFAGIIYALLVRIFTYNWVEGWAGIMIAVLFLGGIQLISVGILGEYIGRIYNEVKKRPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCH
YVVEEYVGFNSEDLKMSRSPVIRHFSYHDNHIK
HHHHHHHCCCCHHHHCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MQLLSLVIPCYNEEAVIDETIKRLKTFCSERNDLDVELILVDDGSRDRTRMLLKSYASDD
CCHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCC
TRIKVIVFARNFGHQIAVTAGIDAARGDAVVLIDADLQDPPEVIHKMIAKWREGYDVIYG
CEEEEEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEC
TRAVRIGESAFKQFSARFFYRFLNKLSDIPIPLDTGDFRLMSRDVVDTLKAMPENDRFVR
CEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
GMVSWVGFKQTALPYTRQERFAGESKYPLKKMLRFANDGILSFSTKPLQISISLGLLSAA
HHHHHHCCHHHCCCCHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCEEEEEHHHHHHHH
LAFAGIIYALLVRIFTYNWVEGWAGIMIAVLFLGGIQLISVGILGEYIGRIYNEVKKRPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCH
YVVEEYVGFNSEDLKMSRSPVIRHFSYHDNHIK
HHHHHHHCCCCHHHHCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]