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The map label for this gene is dnaC [H]

Identifier: 119356181

GI number: 119356181

Start: 374682

End: 376214

Strand: Reverse

Name: dnaC [H]

Synonym: Cpha266_0342

Alternate gene names: 119356181

Gene position: 376214-374682 (Counterclockwise)

Preceding gene: 119356182

Following gene: 119356180

Centisome position: 12.0

GC content: 48.99

Gene sequence:

>1533_bases
ATGATCAAGCCTAAAGCGGATATACTGGATTTCAGCAAGGACATCGATTTCAACCTCGAAGGCCGTGTTCCCCCCTACTC
AACCGAGATTGAACAGGAGGTGCTCGCCTGTGTTCTCCTGGAGGATGATCCTGTTGAACAGGTAATCCAGATCTTCGGCG
ACAGCGCTGAAGAGGTTTTTTTCGAACGCCGCCACCGTCTGATCTTCAAGTCGATGATGCAGCTTTACAATAAAAGGCAG
GCTATCGATCTGATAACCGTGAGCGAGGAACTGCTTAAAATGAATGAGCTGGACAATATCGGCGGCAGACACTACCTTGC
CGAACTCTCCGGCAAAGTCATCAGCGCGGCAAATGTCGAATATTATGCACGGCTTGCAAAGGAGAAATATCTCTACCGGC
GAATGATTTCGATATCGGCAAAGGTATCGGGAGCCGCATACAGTTCATCAATGGATATTTTTGATCTGGTTGAACATGCA
TCGCAGCAATTTTTCAATATTTCACAGGCAGGCATCAAAAAGAAAGCATCTCCGATCAAGGATCTGGTAAAAAACGGCAT
CAGAATGCTTGAAACCCTCAGGGCTTCACAGTCGTCCATTACCGGTGTAGGATCCGGGTTTTCCGATCTCGATCAGTTTA
CCGCAGGGTTTCAGTCTTCCGACATGATTATCATTGCAGCAAGACCTTCTGCCGGTAAAACCGCATTCGCCCTTGCCCTT
GCAAGAAACGCCGCTGTTGATTTCAATACCCCGGTTCTTTTTTTCAGCCTGGAAATGGCCGAGGTTCAGCTTGCCGTCAG
GCTCATGTGTGCCGAGGCATATGTTGAATCGCAGCTTGTTCGAACGGGTCGAATCACGCCGGAAATGATGAGCAAAATCA
TCAACAGTATGGACAAGCTCAATGAAGCAAAACTGTTCATTGACGATACCCCCGGCATTTCGATTATGGAGCTGACCGCA
AAAACCCGCAGAATGAAGCAGGAGCACAACATCGGAATGGTTGTTGTTGATTATCTCCAGCTTGTCACACCGGTCAAGGA
TGGAAAAACAAACCGCGAACAGGAGATCGCACAAATATCCCGATCGCTGAAAGCGCTCGCCAAAGAGCTTAACATTCCGG
TTATCGCTCTGGCGCAGTTGAACAGATCCGTTGAACAGCGCTCAGGCGACAGAAGACCTCAGTTGAGCGATCTGAGGGAA
TCCGGCTCAATTGAACAGGACGCTGACGTTGTCATGTTCCTTTCGAGACCGGAGATGTATAACATTCAGACTTTTTCAGA
CGGCTCTTCAACCAAGAATATGGTAGAGGTGGTTATCGGCAAGCAGCGAAACGGCCCTATCGGCGATATTCGCATCCTCT
TCCTCAAACAATACGGACGCTTCCAATCGGCAGCGACAAGCTATTTGAGCAACACCGATGAGCAGAACGGTGGATCGGCC
AACGAACGCAATCTACCCCCTGAAGCACCCGCACTCCAGAAAACCCAAATGAGCGCAAACACCTTCATTAACGCCGACGA
TGCACCTTTTTAA

Upstream 100 bases:

>100_bases
GGTTGGAAAAAAGCCTGCTGGGAGGATGTTCAGATGATGCGTCAGCACTATGATAAACTTTGCTCAGCCGAAGCACATTC
AAGAACCATGGTAACAAACA

Downstream 100 bases:

>100_bases
GACTGTGCCCTATGCCTGAACAGAAAAAAAACACACTGAAGGGAGTTCTTCCCTCAAAAAAACAGAGCCGTTCAAATCGA
AGCGATGGCGGAAATATAAA

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MIKPKADILDFSKDIDFNLEGRVPPYSTEIEQEVLACVLLEDDPVEQVIQIFGDSAEEVFFERRHRLIFKSMMQLYNKRQ
AIDLITVSEELLKMNELDNIGGRHYLAELSGKVISAANVEYYARLAKEKYLYRRMISISAKVSGAAYSSSMDIFDLVEHA
SQQFFNISQAGIKKKASPIKDLVKNGIRMLETLRASQSSITGVGSGFSDLDQFTAGFQSSDMIIIAARPSAGKTAFALAL
ARNAAVDFNTPVLFFSLEMAEVQLAVRLMCAEAYVESQLVRTGRITPEMMSKIINSMDKLNEAKLFIDDTPGISIMELTA
KTRRMKQEHNIGMVVVDYLQLVTPVKDGKTNREQEIAQISRSLKALAKELNIPVIALAQLNRSVEQRSGDRRPQLSDLRE
SGSIEQDADVVMFLSRPEMYNIQTFSDGSSTKNMVEVVIGKQRNGPIGDIRILFLKQYGRFQSAATSYLSNTDEQNGGSA
NERNLPPEAPALQKTQMSANTFINADDAPF

Sequences:

>Translated_510_residues
MIKPKADILDFSKDIDFNLEGRVPPYSTEIEQEVLACVLLEDDPVEQVIQIFGDSAEEVFFERRHRLIFKSMMQLYNKRQ
AIDLITVSEELLKMNELDNIGGRHYLAELSGKVISAANVEYYARLAKEKYLYRRMISISAKVSGAAYSSSMDIFDLVEHA
SQQFFNISQAGIKKKASPIKDLVKNGIRMLETLRASQSSITGVGSGFSDLDQFTAGFQSSDMIIIAARPSAGKTAFALAL
ARNAAVDFNTPVLFFSLEMAEVQLAVRLMCAEAYVESQLVRTGRITPEMMSKIINSMDKLNEAKLFIDDTPGISIMELTA
KTRRMKQEHNIGMVVVDYLQLVTPVKDGKTNREQEIAQISRSLKALAKELNIPVIALAQLNRSVEQRSGDRRPQLSDLRE
SGSIEQDADVVMFLSRPEMYNIQTFSDGSSTKNMVEVVIGKQRNGPIGDIRILFLKQYGRFQSAATSYLSNTDEQNGGSA
NERNLPPEAPALQKTQMSANTFINADDAPF
>Mature_510_residues
MIKPKADILDFSKDIDFNLEGRVPPYSTEIEQEVLACVLLEDDPVEQVIQIFGDSAEEVFFERRHRLIFKSMMQLYNKRQ
AIDLITVSEELLKMNELDNIGGRHYLAELSGKVISAANVEYYARLAKEKYLYRRMISISAKVSGAAYSSSMDIFDLVEHA
SQQFFNISQAGIKKKASPIKDLVKNGIRMLETLRASQSSITGVGSGFSDLDQFTAGFQSSDMIIIAARPSAGKTAFALAL
ARNAAVDFNTPVLFFSLEMAEVQLAVRLMCAEAYVESQLVRTGRITPEMMSKIINSMDKLNEAKLFIDDTPGISIMELTA
KTRRMKQEHNIGMVVVDYLQLVTPVKDGKTNREQEIAQISRSLKALAKELNIPVIALAQLNRSVEQRSGDRRPQLSDLRE
SGSIEQDADVVMFLSRPEMYNIQTFSDGSSTKNMVEVVIGKQRNGPIGDIRILFLKQYGRFQSAATSYLSNTDEQNGGSA
NERNLPPEAPALQKTQMSANTFINADDAPF

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=457, Percent_Identity=43.5448577680525, Blast_Score=349, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 56867; Mature: 56867

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKPKADILDFSKDIDFNLEGRVPPYSTEIEQEVLACVLLEDDPVEQVIQIFGDSAEEVF
CCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCHHHHHHHHCCCHHHHH
FERRHRLIFKSMMQLYNKRQAIDLITVSEELLKMNELDNIGGRHYLAELSGKVISAANVE
HHHHHHHHHHHHHHHHCCHHHHEEEHHHHHHHHHHHHCCCCCHHHHHHHCCCEEECCCHH
YYARLAKEKYLYRRMISISAKVSGAAYSSSMDIFDLVEHASQQFFNISQAGIKKKASPIK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
DLVKNGIRMLETLRASQSSITGVGSGFSDLDQFTAGFQSSDMIIIAARPSAGKTAFALAL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHH
ARNAAVDFNTPVLFFSLEMAEVQLAVRLMCAEAYVESQLVRTGRITPEMMSKIINSMDKL
HHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
NEAKLFIDDTPGISIMELTAKTRRMKQEHNIGMVVVDYLQLVTPVKDGKTNREQEIAQIS
CCCEEEEECCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RSLKALAKELNIPVIALAQLNRSVEQRSGDRRPQLSDLRESGSIEQDADVVMFLSRPEMY
HHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCEE
NIQTFSDGSSTKNMVEVVIGKQRNGPIGDIRILFLKQYGRFQSAATSYLSNTDEQNGGSA
EEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEEHHHCHHHHHHHHHHHCCCCCCCCCC
NERNLPPEAPALQKTQMSANTFINADDAPF
CCCCCCCCCCCHHHHHCCCCCEECCCCCCC
>Mature Secondary Structure
MIKPKADILDFSKDIDFNLEGRVPPYSTEIEQEVLACVLLEDDPVEQVIQIFGDSAEEVF
CCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCHHHHHHHHCCCHHHHH
FERRHRLIFKSMMQLYNKRQAIDLITVSEELLKMNELDNIGGRHYLAELSGKVISAANVE
HHHHHHHHHHHHHHHHCCHHHHEEEHHHHHHHHHHHHCCCCCHHHHHHHCCCEEECCCHH
YYARLAKEKYLYRRMISISAKVSGAAYSSSMDIFDLVEHASQQFFNISQAGIKKKASPIK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
DLVKNGIRMLETLRASQSSITGVGSGFSDLDQFTAGFQSSDMIIIAARPSAGKTAFALAL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHH
ARNAAVDFNTPVLFFSLEMAEVQLAVRLMCAEAYVESQLVRTGRITPEMMSKIINSMDKL
HHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
NEAKLFIDDTPGISIMELTAKTRRMKQEHNIGMVVVDYLQLVTPVKDGKTNREQEIAQIS
CCCEEEEECCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RSLKALAKELNIPVIALAQLNRSVEQRSGDRRPQLSDLRESGSIEQDADVVMFLSRPEMY
HHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCEE
NIQTFSDGSSTKNMVEVVIGKQRNGPIGDIRILFLKQYGRFQSAATSYLSNTDEQNGGSA
EEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEEHHHCHHHHHHHHHHHCCCCCCCCCC
NERNLPPEAPALQKTQMSANTFINADDAPF
CCCCCCCCCCCHHHHHCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]