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The map label for this gene is fur [H]

Identifier: 119356156

GI number: 119356156

Start: 347331

End: 347825

Strand: Direct

Name: fur [H]

Synonym: Cpha266_0314

Alternate gene names: 119356156

Gene position: 347331-347825 (Clockwise)

Preceding gene: 119356155

Following gene: 119356158

Centisome position: 11.08

GC content: 45.25

Gene sequence:

>495_bases
ATGGCTGATATATCGCTACAAACGAAGAAAGAGACGAGCGACAAAACAAGGCAAGCTGAAAGCCTTTTCAAGTCATTCAT
GAAAGAGCAAGGATTGCGTTGCACAACGGAACGCATTGCTGTGTTGCGAGAACTTTATCGATCAAATACCCATCTTGACG
CGGATGAGATTTTTATTCGCCTTAAAAAGAAGCAGGTAGGCATTTCGCGTGCCACCGTCTATCATACGCTTAACCTGTTG
TTTAAATTTCATCTGGTTTCCAAAATCGATCTTGGGCACAAGCACACCCATTACGAAAAATCGCACGGGGTGACCAACCA
TCTGCATATCATTTGTGAAAAATGCGGAAATGTTGTCGAGGTGTCAGAGAGTGGACTGTCCGAACTGCTCGACAGGGTGT
GCCGGGAAAACGGCTTTGAGCTTGGCAGTTTCAGTCTCCAGGTCTTCGGAAAATGTGTTGGAAATTGTGATGAAAATTGC
CCGAAGCAGAAGTGA

Upstream 100 bases:

>100_bases
CGATACTCCCCAAAGCCAGGGCTTTTTTTGCCATGCCGAAAAAAAAGGGAATGGTATCTGTTGCGGTATTGATCATTTAT
TATCCGGTAAGAGCACTATT

Downstream 100 bases:

>100_bases
TCATGCTGGGTGCCGTTGATTTTTCGCTGGAGGAAATGGCTTTTTATGCCGCGCGCAGATAGGTTTCTGCGCGCGTGCGT
GCATGGTTATACAGGGTTCT

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MADISLQTKKETSDKTRQAESLFKSFMKEQGLRCTTERIAVLRELYRSNTHLDADEIFIRLKKKQVGISRATVYHTLNLL
FKFHLVSKIDLGHKHTHYEKSHGVTNHLHIICEKCGNVVEVSESGLSELLDRVCRENGFELGSFSLQVFGKCVGNCDENC
PKQK

Sequences:

>Translated_164_residues
MADISLQTKKETSDKTRQAESLFKSFMKEQGLRCTTERIAVLRELYRSNTHLDADEIFIRLKKKQVGISRATVYHTLNLL
FKFHLVSKIDLGHKHTHYEKSHGVTNHLHIICEKCGNVVEVSESGLSELLDRVCRENGFELGSFSLQVFGKCVGNCDENC
PKQK
>Mature_163_residues
ADISLQTKKETSDKTRQAESLFKSFMKEQGLRCTTERIAVLRELYRSNTHLDADEIFIRLKKKQVGISRATVYHTLNLLF
KFHLVSKIDLGHKHTHYEKSHGVTNHLHIICEKCGNVVEVSESGLSELLDRVCRENGFELGSFSLQVFGKCVGNCDENCP
KQK

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18740; Mature: 18609

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADISLQTKKETSDKTRQAESLFKSFMKEQGLRCTTERIAVLRELYRSNTHLDADEIFIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
LKKKQVGISRATVYHTLNLLFKFHLVSKIDLGHKHTHYEKSHGVTNHLHIICEKCGNVVE
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHCCEEE
VSESGLSELLDRVCRENGFELGSFSLQVFGKCVGNCDENCPKQK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ADISLQTKKETSDKTRQAESLFKSFMKEQGLRCTTERIAVLRELYRSNTHLDADEIFIR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
LKKKQVGISRATVYHTLNLLFKFHLVSKIDLGHKHTHYEKSHGVTNHLHIICEKCGNVVE
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHCCEEE
VSESGLSELLDRVCRENGFELGSFSLQVFGKCVGNCDENCPKQK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]