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The map label for this gene is cobB [H]

Identifier: 119356154

GI number: 119356154

Start: 345213

End: 346583

Strand: Direct

Name: cobB [H]

Synonym: Cpha266_0312

Alternate gene names: 119356154

Gene position: 345213-346583 (Clockwise)

Preceding gene: 119356153

Following gene: 119356155

Centisome position: 11.02

GC content: 51.86

Gene sequence:

>1371_bases
ATGGAAAAACTTGATTTATGCAAAAAAAAGCCGGCCTTTATGCTTGCCGCACCCTCAAGCGGGTCGGGAAAAACAACGCT
TACGCTCGCACTTCTCAGGATTCTGGCGCGGCGGGGATATCGCGTACAGCCGTTCAAGTGCGGGCCCGACTATCTCGATA
CCCGTTTACACTCCCTGGCAGCCTCATATGGAAGCATGGTTTCGGATGGCATTAATCTCGATACCTTCATGGCTTCGGAA
TCGCATGTTAAAGAGTTGTTCAGCCGATATTCATGCGGATCGGACGCTTCGGTTGTCGAAGGGGTGATGGGGCTTTTTGA
CGGGGCTGAAAAAGCGCGGGGCAGTAGTGCGGAAATCGCAAAACTGCTCGGTATTCCGGTCATCATGGTAGTGAATGCAC
AAAGTATGGCCTATTCGGCAGCGCCGCTTCTCTATGGTTACAGAACTTTCGATCCCGACGTGCACCTTGTCGGCGTGATT
TTCAATCAGGTCAATACTCCGTCGCACTATCGTTATCTTGAAGAGGCGGCTTTCGATGCGGGGGTTGATCCCCTTGGCTA
TGTTCCCCGTCATGAACCGATTGTCATCAGTGAGCGGCATCTTGGTCTCAATACCTCTTCCAGTTATGACCGGCAGGGAG
CAATTGAGGCCATGGCGGATCATATTGAAAAGAGCGTTGCCGTCGATCGGCTGCTGGAACTTGTCGGCAGAGATCGGGAA
TCCTTTTCAGGCAGCACTTCCCTTGATTTTCATCAACGGGAGCGGGGCGAAAAGGTCATTGCCGTTGCAAGGGACGAGGC
ATTCAATTTTACCTATCTGGAGAATCTCGACGTGCTCAGCCAATTTGGCAGGATAGAATTTTTCAGCCCTATGGAAGATG
GCCGTCTTCCAGCATGCGATCTGCTCTATCTTGCAGGAGGTTATCCTGAACTCTACGCCGAAACCCTCTCTTCGAACAGC
GAAATGAGAAGAGCCATTGCAGCCTACTGCCTGGGAGGGGGGGCTGCCTATGCCGAGTGTGGCGGGATGATGTATCTCGG
AGCAGCAATGACTCTTGGTGACGGGTTGCGCTATCCCATGTGTGGAGTTCTTGACCTCGATACGACCATGCAGGATTCTC
GTCTCACGCTTGGTTATCGTAAAGTTCGACTCGACACGGGCTATACAAAAGAGCTTCGCGGCCATGAGTTTCACTACTCC
CGCATCGAAAGATCGGGTGAACTGCATACGATCGCATCCATAACAAATGCGCGTGACGAAGCGACAGAAACCCTTCTCTT
TCGCCGGCAGAACACCTTTGCCTCATATCTGCATCTCTACTGGGGAGAAACAAGGGATTTCCCGGCATTTCTTTTGAACA
GAGAGTCGTAA

Upstream 100 bases:

>100_bases
GGTAAACAGCGACAAGCTTCAGGGGGCTCTCAATTACACCTTTATCTACCCCGATCCGGTAGCTCAACTCGGGTAAGGAT
CCCTGAATCGATTGTCCGAT

Downstream 100 bases:

>100_bases
CCGGGGTTGAACAGCAGTGGGTACATTATTACCGGAGGCCCGGGAAGCGGAAAAAGCACGCTGCTTGAAGCGATGCGTGA
TGCAGGGTATTGCTGTTTCA

Product: cobyrinate a,c-diamide synthase / hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MEKLDLCKKKPAFMLAAPSSGSGKTTLTLALLRILARRGYRVQPFKCGPDYLDTRLHSLAASYGSMVSDGINLDTFMASE
SHVKELFSRYSCGSDASVVEGVMGLFDGAEKARGSSAEIAKLLGIPVIMVVNAQSMAYSAAPLLYGYRTFDPDVHLVGVI
FNQVNTPSHYRYLEEAAFDAGVDPLGYVPRHEPIVISERHLGLNTSSSYDRQGAIEAMADHIEKSVAVDRLLELVGRDRE
SFSGSTSLDFHQRERGEKVIAVARDEAFNFTYLENLDVLSQFGRIEFFSPMEDGRLPACDLLYLAGGYPELYAETLSSNS
EMRRAIAAYCLGGGAAYAECGGMMYLGAAMTLGDGLRYPMCGVLDLDTTMQDSRLTLGYRKVRLDTGYTKELRGHEFHYS
RIERSGELHTIASITNARDEATETLLFRRQNTFASYLHLYWGETRDFPAFLLNRES

Sequences:

>Translated_456_residues
MEKLDLCKKKPAFMLAAPSSGSGKTTLTLALLRILARRGYRVQPFKCGPDYLDTRLHSLAASYGSMVSDGINLDTFMASE
SHVKELFSRYSCGSDASVVEGVMGLFDGAEKARGSSAEIAKLLGIPVIMVVNAQSMAYSAAPLLYGYRTFDPDVHLVGVI
FNQVNTPSHYRYLEEAAFDAGVDPLGYVPRHEPIVISERHLGLNTSSSYDRQGAIEAMADHIEKSVAVDRLLELVGRDRE
SFSGSTSLDFHQRERGEKVIAVARDEAFNFTYLENLDVLSQFGRIEFFSPMEDGRLPACDLLYLAGGYPELYAETLSSNS
EMRRAIAAYCLGGGAAYAECGGMMYLGAAMTLGDGLRYPMCGVLDLDTTMQDSRLTLGYRKVRLDTGYTKELRGHEFHYS
RIERSGELHTIASITNARDEATETLLFRRQNTFASYLHLYWGETRDFPAFLLNRES
>Mature_456_residues
MEKLDLCKKKPAFMLAAPSSGSGKTTLTLALLRILARRGYRVQPFKCGPDYLDTRLHSLAASYGSMVSDGINLDTFMASE
SHVKELFSRYSCGSDASVVEGVMGLFDGAEKARGSSAEIAKLLGIPVIMVVNAQSMAYSAAPLLYGYRTFDPDVHLVGVI
FNQVNTPSHYRYLEEAAFDAGVDPLGYVPRHEPIVISERHLGLNTSSSYDRQGAIEAMADHIEKSVAVDRLLELVGRDRE
SFSGSTSLDFHQRERGEKVIAVARDEAFNFTYLENLDVLSQFGRIEFFSPMEDGRLPACDLLYLAGGYPELYAETLSSNS
EMRRAIAAYCLGGGAAYAECGGMMYLGAAMTLGDGLRYPMCGVLDLDTTMQDSRLTLGYRKVRLDTGYTKELRGHEFHYS
RIERSGELHTIASITNARDEATETLLFRRQNTFASYLHLYWGETRDFPAFLLNRES

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 50553; Mature: 50553

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLDLCKKKPAFMLAAPSSGSGKTTLTLALLRILARRGYRVQPFKCGPDYLDTRLHSLA
CCCHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHH
ASYGSMVSDGINLDTFMASESHVKELFSRYSCGSDASVVEGVMGLFDGAEKARGSSAEIA
HHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHCCCCHHHHH
KLLGIPVIMVVNAQSMAYSAAPLLYGYRTFDPDVHLVGVIFNQVNTPSHYRYLEEAAFDA
HHHCCCEEEEECCHHHHHHCCHHHCCCEECCCCEEEHEEHHHCCCCCHHHHHHHHHHHHC
GVDPLGYVPRHEPIVISERHLGLNTSSSYDRQGAIEAMADHIEKSVAVDRLLELVGRDRE
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SFSGSTSLDFHQRERGEKVIAVARDEAFNFTYLENLDVLSQFGRIEFFSPMEDGRLPACD
HCCCCCCCCHHHHHCCCEEEEEECCCCCCCHHHHCHHHHHHCCCEEEECCCCCCCCCHHH
LLYLAGGYPELYAETLSSNSEMRRAIAAYCLGGGAAYAECGGMMYLGAAMTLGDGLRYPM
EEEECCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCEEEEHHHHHHCCCCCCCC
CGVLDLDTTMQDSRLTLGYRKVRLDTGYTKELRGHEFHYSRIERSGELHTIASITNARDE
CCEEECCCCCCCCEEEECEEEEEECCCCCHHHCCCCHHHHHHHCCCCEEEHHHHHCCHHH
ATETLLFRRQNTFASYLHLYWGETRDFPAFLLNRES
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCC
>Mature Secondary Structure
MEKLDLCKKKPAFMLAAPSSGSGKTTLTLALLRILARRGYRVQPFKCGPDYLDTRLHSLA
CCCHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHH
ASYGSMVSDGINLDTFMASESHVKELFSRYSCGSDASVVEGVMGLFDGAEKARGSSAEIA
HHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHCCCCHHHHH
KLLGIPVIMVVNAQSMAYSAAPLLYGYRTFDPDVHLVGVIFNQVNTPSHYRYLEEAAFDA
HHHCCCEEEEECCHHHHHHCCHHHCCCEECCCCEEEHEEHHHCCCCCHHHHHHHHHHHHC
GVDPLGYVPRHEPIVISERHLGLNTSSSYDRQGAIEAMADHIEKSVAVDRLLELVGRDRE
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SFSGSTSLDFHQRERGEKVIAVARDEAFNFTYLENLDVLSQFGRIEFFSPMEDGRLPACD
HCCCCCCCCHHHHHCCCEEEEEECCCCCCCHHHHCHHHHHHCCCEEEECCCCCCCCCHHH
LLYLAGGYPELYAETLSSNSEMRRAIAAYCLGGGAAYAECGGMMYLGAAMTLGDGLRYPM
EEEECCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCEEEEHHHHHHCCCCCCCC
CGVLDLDTTMQDSRLTLGYRKVRLDTGYTKELRGHEFHYSRIERSGELHTIASITNARDE
CCEEECCCCCCCCEEEECEEEEEECCCCCHHHCCCCHHHHHHHCCCCEEEHHHHHCCHHH
ATETLLFRRQNTFASYLHLYWGETRDFPAFLLNRES
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA