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The map label for this gene is 119356060

Identifier: 119356060

GI number: 119356060

Start: 236076

End: 237254

Strand: Reverse

Name: 119356060

Synonym: Cpha266_0213

Alternate gene names: NA

Gene position: 237254-236076 (Counterclockwise)

Preceding gene: 119356061

Following gene: 119356058

Centisome position: 7.57

GC content: 47.92

Gene sequence:

>1179_bases
ATGCGACTAATTCTTATGACCGGAAAAGGTGGTGTTGGAAAAACATCCATGGCTGCAGCTACCGGACTTCGGTGTGCCGA
ACTTGGCTATAAAACTCTCGTTCTCAGTACTGATCCTGCACATTCGCTGGCCGACAGTTTTGATATGGCGCTCGGTCACA
ACCCCAACAGAGTCTCGAATAATCTTTGGGGCGCAGAGCTCGATGTTCTCAAGGAACTCGAACAGAACTGGGGCACCGTG
AAACGATATATAACCGGAGTTCTTCAGGCAAGGGGTCTTGAAGGTATTCAGGCAGAAGAACTTGCCATCCTTCCGGGAAT
GGATGAAATTTTCGGACTGGTGAGAGTATTCCGCCACCACAAGGAGGGCGACTACGATGTGCTTATCATCGACTCAGCTC
CTACCGGAACAGCATTGCGACTTTTAAGCATTCCTGAGGTAGCCGGCTGGTATATGAGAAGACTTTACAAACCTTTTGAA
AAAGTCGCGCTCTATCTCAGACCTCTTGTCGAACCGATCTTCAGACCTCTTGCCGGCTTTTCCTTACCAGACAAAGAGAT
GATGGATGTGCCATACGAATTTTATGAACAAATCGACGCTCTCGGCAAAATCCTTACCGACCACGCCGTCACATCCGTCA
GACTTGTCACCAACCCAGAAAAGATGGTTATCAAGGAGTCCCTTCGCGCTCACGCCTATCTTGGTCTTTATAACATCGCT
GTTGATCTGGTCATTGCCAATCGGATCATACCGCCAGAGGTCACCGATCCCTATTTCACATTCTGGAAAGAGAATCAAAC
GCTCTATCGACAAGAAATCCAGGATAACTTCGCGCCCCTTCCCGTCAAGGAAGTCCCACTCTATTCTCGTGAGATATGCG
GCATGCAGACCCTCGAAAAACTCAAGGAGATGCTTTACGGTAACGAAGACCCTGCACAAGTCTATTATAAAGAGCAAACA
TTTCAGATAAAACAGACAACCCAAGGATTTACTCTGGAGCTCTATATCCCCGGAATTCCAAAGGATCAGATTCAGTTGGG
AAAAAATGGTGACGAACTGCACGTCCGCATAGGTAATCACCGCCGCAATATGGTGCTTCCTCAGGCACTCGCCTCACTGA
AAACTACCGGAGCGGAAATGGATGGAGATCACCTCATCATCCATTTTGTTGAACCATAA

Upstream 100 bases:

>100_bases
TCCCTTCACAAAAATTTTCAGAGCTGCCGAAAACTTATAGCGGAAAAAAAATCGTTGTACTAAAGGAGATCCATACCCTT
CAACTCTTGTATTCTTCTTT

Downstream 100 bases:

>100_bases
ACCATGCGCTCATTTTTTATTTTTAAATAACCGTCAAAAAAAAAGTAAGTTAAAAGTTTTAACACATAAAAGCATCTCTC
ATAATTGCCGGGAGCGCTTC

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MRLILMTGKGGVGKTSMAAATGLRCAELGYKTLVLSTDPAHSLADSFDMALGHNPNRVSNNLWGAELDVLKELEQNWGTV
KRYITGVLQARGLEGIQAEELAILPGMDEIFGLVRVFRHHKEGDYDVLIIDSAPTGTALRLLSIPEVAGWYMRRLYKPFE
KVALYLRPLVEPIFRPLAGFSLPDKEMMDVPYEFYEQIDALGKILTDHAVTSVRLVTNPEKMVIKESLRAHAYLGLYNIA
VDLVIANRIIPPEVTDPYFTFWKENQTLYRQEIQDNFAPLPVKEVPLYSREICGMQTLEKLKEMLYGNEDPAQVYYKEQT
FQIKQTTQGFTLELYIPGIPKDQIQLGKNGDELHVRIGNHRRNMVLPQALASLKTTGAEMDGDHLIIHFVEP

Sequences:

>Translated_392_residues
MRLILMTGKGGVGKTSMAAATGLRCAELGYKTLVLSTDPAHSLADSFDMALGHNPNRVSNNLWGAELDVLKELEQNWGTV
KRYITGVLQARGLEGIQAEELAILPGMDEIFGLVRVFRHHKEGDYDVLIIDSAPTGTALRLLSIPEVAGWYMRRLYKPFE
KVALYLRPLVEPIFRPLAGFSLPDKEMMDVPYEFYEQIDALGKILTDHAVTSVRLVTNPEKMVIKESLRAHAYLGLYNIA
VDLVIANRIIPPEVTDPYFTFWKENQTLYRQEIQDNFAPLPVKEVPLYSREICGMQTLEKLKEMLYGNEDPAQVYYKEQT
FQIKQTTQGFTLELYIPGIPKDQIQLGKNGDELHVRIGNHRRNMVLPQALASLKTTGAEMDGDHLIIHFVEP
>Mature_392_residues
MRLILMTGKGGVGKTSMAAATGLRCAELGYKTLVLSTDPAHSLADSFDMALGHNPNRVSNNLWGAELDVLKELEQNWGTV
KRYITGVLQARGLEGIQAEELAILPGMDEIFGLVRVFRHHKEGDYDVLIIDSAPTGTALRLLSIPEVAGWYMRRLYKPFE
KVALYLRPLVEPIFRPLAGFSLPDKEMMDVPYEFYEQIDALGKILTDHAVTSVRLVTNPEKMVIKESLRAHAYLGLYNIA
VDLVIANRIIPPEVTDPYFTFWKENQTLYRQEIQDNFAPLPVKEVPLYSREICGMQTLEKLKEMLYGNEDPAQVYYKEQT
FQIKQTTQGFTLELYIPGIPKDQIQLGKNGDELHVRIGNHRRNMVLPQALASLKTTGAEMDGDHLIIHFVEP

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=281, Percent_Identity=23.1316725978648, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17557003, Length=285, Percent_Identity=24.9122807017544, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320103, Length=320, Percent_Identity=25.625, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24586297, Length=311, Percent_Identity=25.08038585209, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348
- InterPro:   IPR008978 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 44287; Mature: 44287

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLILMTGKGGVGKTSMAAATGLRCAELGYKTLVLSTDPAHSLADSFDMALGHNPNRVSN
CEEEEEECCCCCCCHHHHHHHCCHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHCC
NLWGAELDVLKELEQNWGTVKRYITGVLQARGLEGIQAEELAILPGMDEIFGLVRVFRHH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHC
KEGDYDVLIIDSAPTGTALRLLSIPEVAGWYMRRLYKPFEKVALYLRPLVEPIFRPLAGF
CCCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLPDKEMMDVPYEFYEQIDALGKILTDHAVTSVRLVTNPEKMVIKESLRAHAYLGLYNIA
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
VDLVIANRIIPPEVTDPYFTFWKENQTLYRQEIQDNFAPLPVKEVPLYSREICGMQTLEK
HHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCHHHCCCHHHHHCCHHHHHH
LKEMLYGNEDPAQVYYKEQTFQIKQTTQGFTLELYIPGIPKDQIQLGKNGDELHVRIGNH
HHHHHCCCCCHHHEEEECCEEEEEECCCCEEEEEEECCCCHHHHEECCCCCEEEEEECCC
RRNMVLPQALASLKTTGAEMDGDHLIIHFVEP
CCCEEHHHHHHHHHHCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MRLILMTGKGGVGKTSMAAATGLRCAELGYKTLVLSTDPAHSLADSFDMALGHNPNRVSN
CEEEEEECCCCCCCHHHHHHHCCHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHCC
NLWGAELDVLKELEQNWGTVKRYITGVLQARGLEGIQAEELAILPGMDEIFGLVRVFRHH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHC
KEGDYDVLIIDSAPTGTALRLLSIPEVAGWYMRRLYKPFEKVALYLRPLVEPIFRPLAGF
CCCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLPDKEMMDVPYEFYEQIDALGKILTDHAVTSVRLVTNPEKMVIKESLRAHAYLGLYNIA
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
VDLVIANRIIPPEVTDPYFTFWKENQTLYRQEIQDNFAPLPVKEVPLYSREICGMQTLEK
HHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCHHHCCCHHHHHCCHHHHHH
LKEMLYGNEDPAQVYYKEQTFQIKQTTQGFTLELYIPGIPKDQIQLGKNGDELHVRIGNH
HHHHHCCCCCHHHEEEECCEEEEEECCCCEEEEEEECCCCHHHHEECCCCCEEEEEECCC
RRNMVLPQALASLKTTGAEMDGDHLIIHFVEP
CCCEEHHHHHHHHHHCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]