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The map label for this gene is cobB [H]

Identifier: 119355976

GI number: 119355976

Start: 147068

End: 148495

Strand: Direct

Name: cobB [H]

Synonym: Cpha266_0126

Alternate gene names: 119355976

Gene position: 147068-148495 (Clockwise)

Preceding gene: 119355975

Following gene: 119355977

Centisome position: 4.69

GC content: 52.87

Gene sequence:

>1428_bases
ATGGATGCAGTAACGTTGCCGCGGTTGATGATTTCGGCCGCACAGAAAAGTTCCGGCAAAACAACGATCAGTCTTGGTCT
GTTATCTCATCTCAAAAGCAGAGGCGTAGCGGTAAGAAGTTTTAAAAAAGGCCCGGACTATATCGATCCTATGTGGCACA
AGCTTGCATCCGGCAGCGAGTGCTACAATCTCGATCCGTACCTTATGGGCCAGGAGGGGTGTCTCGACTCGTTTTTTAAA
AACAGTCGGAACGGAAACAGTGATTTTTGCCTCATCGAAGGTAATCACGGACTTCATGACGGTCTCTCTCTTGATGGGTC
TGACAGCAGCGCAGGTCTTGCTTCAATGCTCAAGACGCCTGTACTTCTGGTGGTTGACAGCAGAAAAACGAACAGGGGGG
TAGCCGCGCTGGTTATGGGCATGCAGGCGATGCAGCCGCAGGCGGACATTGCCGGGGTTATTTTAAATCAGGTTCAAAGC
GCCCGTCAGGCGGCGAAGCAGAAACTTGCTATTGAGCACTATTGCAAGGTGCCTGTTTTTGGCGCGATCCCTGTTGATGA
AGAGCTGGTCATTCCCGAGAGGCACCTGGGACTTACAACGGTGGGAGAAACCGCCGATGCCGCTAAATTTATTACAGGTG
CGGCAGAGCGGCTTGAGCGCTATTGCGATATGGCCGCTATCAGGGCGCTGTTTTCCATGGCCTCCCCCATCGGGATGCCG
CCGCTTGAAACCCGTGGAATCAACCCTGTCGCTCGGGCAAGAGTCGGCGTGTTCAGAGATGCGGCGTTCTGTTTTTACTA
CCCTGACAACCTTGCCGCGCTTCAGGAACATGGCGCTGAGCTTATTTTTATCGACTCCATGTCGGAGAGCTCGCTTCCCG
ATATTGACGGTCTCTATCTGGGGGGCGGATTTCCCGAGTCTTTTTTCGATGCCATAAGCTCACGCCGAGGACTATTAAGG
GATGTCCGCGAACGAGTTAAGTCAGGCATGCCGCTGTATGCTGAATGCGGAGGATTGATCTACCTCAGCCGGAGTGCCGA
ATATGGGGGGAAAAGATATGATCTTGCAGGAGTTCTTCCTCTTGATATAGGCTTTCAGCAACGTCCCGCAGGGCATGGGT
ATCTTGATTTAAGGAGTTCCGCCGAAAGCGCATGGTTTAAAACGGGCGAACGGATCAGGGCGCATGAGTTTCATTATTCG
CGTCCGCTTCTGTCGAGCGGAGCCTGTTCCTATCAGTTTGAGGTGCTAAGGGGATATGGCGTAACCGGGGAGCGTGACGG
GGCAGTTGATAACCATGTTTTTGCGTCCTTTGCTCATGTGCATGCGCTGAGTACTCCGGGCTGGGCGCCAAAATTCGTCT
CTCTTGCATCGATATACAAAGATCGCTGTTTATCAGGCTGGGCAGTTCCTCCGCAGCGTCAGGATTGA

Upstream 100 bases:

>100_bases
GAGTACGGCAGGTCAAGGCCATAGCGTGCATGTTGACGGAGGTATTTTTTTTTCGGCTTTTTGAAAAGAGCGGATTTTTG
CGGCTTAGAGGGAGATACAT

Downstream 100 bases:

>100_bases
ACAAAAAAATACGGAGAGAATTTGAAAAATAGCGCATGAATTTGTAACTATATAACCTTACGCATTTGTCGTTGTGTAGT
TGAGTTGTCGGTATCTGTTT

Product: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) / cobyrinate a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MDAVTLPRLMISAAQKSSGKTTISLGLLSHLKSRGVAVRSFKKGPDYIDPMWHKLASGSECYNLDPYLMGQEGCLDSFFK
NSRNGNSDFCLIEGNHGLHDGLSLDGSDSSAGLASMLKTPVLLVVDSRKTNRGVAALVMGMQAMQPQADIAGVILNQVQS
ARQAAKQKLAIEHYCKVPVFGAIPVDEELVIPERHLGLTTVGETADAAKFITGAAERLERYCDMAAIRALFSMASPIGMP
PLETRGINPVARARVGVFRDAAFCFYYPDNLAALQEHGAELIFIDSMSESSLPDIDGLYLGGGFPESFFDAISSRRGLLR
DVRERVKSGMPLYAECGGLIYLSRSAEYGGKRYDLAGVLPLDIGFQQRPAGHGYLDLRSSAESAWFKTGERIRAHEFHYS
RPLLSSGACSYQFEVLRGYGVTGERDGAVDNHVFASFAHVHALSTPGWAPKFVSLASIYKDRCLSGWAVPPQRQD

Sequences:

>Translated_475_residues
MDAVTLPRLMISAAQKSSGKTTISLGLLSHLKSRGVAVRSFKKGPDYIDPMWHKLASGSECYNLDPYLMGQEGCLDSFFK
NSRNGNSDFCLIEGNHGLHDGLSLDGSDSSAGLASMLKTPVLLVVDSRKTNRGVAALVMGMQAMQPQADIAGVILNQVQS
ARQAAKQKLAIEHYCKVPVFGAIPVDEELVIPERHLGLTTVGETADAAKFITGAAERLERYCDMAAIRALFSMASPIGMP
PLETRGINPVARARVGVFRDAAFCFYYPDNLAALQEHGAELIFIDSMSESSLPDIDGLYLGGGFPESFFDAISSRRGLLR
DVRERVKSGMPLYAECGGLIYLSRSAEYGGKRYDLAGVLPLDIGFQQRPAGHGYLDLRSSAESAWFKTGERIRAHEFHYS
RPLLSSGACSYQFEVLRGYGVTGERDGAVDNHVFASFAHVHALSTPGWAPKFVSLASIYKDRCLSGWAVPPQRQD
>Mature_475_residues
MDAVTLPRLMISAAQKSSGKTTISLGLLSHLKSRGVAVRSFKKGPDYIDPMWHKLASGSECYNLDPYLMGQEGCLDSFFK
NSRNGNSDFCLIEGNHGLHDGLSLDGSDSSAGLASMLKTPVLLVVDSRKTNRGVAALVMGMQAMQPQADIAGVILNQVQS
ARQAAKQKLAIEHYCKVPVFGAIPVDEELVIPERHLGLTTVGETADAAKFITGAAERLERYCDMAAIRALFSMASPIGMP
PLETRGINPVARARVGVFRDAAFCFYYPDNLAALQEHGAELIFIDSMSESSLPDIDGLYLGGGFPESFFDAISSRRGLLR
DVRERVKSGMPLYAECGGLIYLSRSAEYGGKRYDLAGVLPLDIGFQQRPAGHGYLDLRSSAESAWFKTGERIRAHEFHYS
RPLLSSGACSYQFEVLRGYGVTGERDGAVDNHVFASFAHVHALSTPGWAPKFVSLASIYKDRCLSGWAVPPQRQD

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 51642; Mature: 51642

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAVTLPRLMISAAQKSSGKTTISLGLLSHLKSRGVAVRSFKKGPDYIDPMWHKLASGSE
CCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHCCCCC
CYNLDPYLMGQEGCLDSFFKNSRNGNSDFCLIEGNHGLHDGLSLDGSDSSAGLASMLKTP
CCCCCCCEECCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
VLLVVDSRKTNRGVAALVMGMQAMQPQADIAGVILNQVQSARQAAKQKLAIEHYCKVPVF
EEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
GAIPVDEELVIPERHLGLTTVGETADAAKFITGAAERLERYCDMAAIRALFSMASPIGMP
ECCCCCCCEECCHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLETRGINPVARARVGVFRDAAFCFYYPDNLAALQEHGAELIFIDSMSESSLPDIDGLYL
CCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCEEEEEECCCCCCCCCCCEEEE
GGGFPESFFDAISSRRGLLRDVRERVKSGMPLYAECGGLIYLSRSAEYGGKRYDLAGVLP
CCCCCHHHHHHHHHCHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCEEEEEEEEE
LDIGFQQRPAGHGYLDLRSSAESAWFKTGERIRAHEFHYSRPLLSSGACSYQFEVLRGYG
ECCCCCCCCCCCCEEEECCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEEHHCCC
VTGERDGAVDNHVFASFAHVHALSTPGWAPKFVSLASIYKDRCLSGWAVPPQRQD
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDAVTLPRLMISAAQKSSGKTTISLGLLSHLKSRGVAVRSFKKGPDYIDPMWHKLASGSE
CCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHCCCCC
CYNLDPYLMGQEGCLDSFFKNSRNGNSDFCLIEGNHGLHDGLSLDGSDSSAGLASMLKTP
CCCCCCCEECCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
VLLVVDSRKTNRGVAALVMGMQAMQPQADIAGVILNQVQSARQAAKQKLAIEHYCKVPVF
EEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
GAIPVDEELVIPERHLGLTTVGETADAAKFITGAAERLERYCDMAAIRALFSMASPIGMP
ECCCCCCCEECCHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLETRGINPVARARVGVFRDAAFCFYYPDNLAALQEHGAELIFIDSMSESSLPDIDGLYL
CCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCEEEEEECCCCCCCCCCCEEEE
GGGFPESFFDAISSRRGLLRDVRERVKSGMPLYAECGGLIYLSRSAEYGGKRYDLAGVLP
CCCCCHHHHHHHHHCHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCEEEEEEEEE
LDIGFQQRPAGHGYLDLRSSAESAWFKTGERIRAHEFHYSRPLLSSGACSYQFEVLRGYG
ECCCCCCCCCCCCEEEECCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEEHHCCC
VTGERDGAVDNHVFASFAHVHALSTPGWAPKFVSLASIYKDRCLSGWAVPPQRQD
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA