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The map label for this gene is rlmH

Identifier: 118582011

GI number: 118582011

Start: 3994314

End: 3994772

Strand: Reverse

Name: rlmH

Synonym: Ppro_3612

Alternate gene names: 118582011

Gene position: 3994772-3994314 (Counterclockwise)

Preceding gene: 118582012

Following gene: 118582010

Centisome position: 99.67

GC content: 63.18

Gene sequence:

>459_bases
GTGAGGCTGCGCGTCCTCTGGGTCGGCAAGAGCCGGGAGGAGTGGGTGAAACAGGCTCTGGCCGACTATGCCACCAGAAT
CCGGCGCTATGCTCCACTGGAACTGGTGGAGGTTCGTGACGAGAAGGGGGCCATGGCCGAGGAGATGCGGCGGCGCGAGT
GCGAACGGCTTGAGAAGCAGATCCCGCCCGGTGCTACGCTGCTGTTGCTGGACGAGCGGGGAGAGCAGATGGATTCTCCC
GGTCTGGCGGCATATATCGGCAAACAGCGCGACAGCGGCACGGCGGATCTGGTCCTCGTCATCGGCGGGGCCTACGGCTT
TTCCGATGCTTTCCGGCGGCGCGGACGGCTGCTCTCCCTGTCTCCCATGACCTTTACCCACCAGATGGTGCGGGTGTTTT
TGCTGGAGCAGCTCTACCGCTCATTTACCATCCTGAACAACGAGCCGTACCACCACTGA

Upstream 100 bases:

>100_bases
ACCGGTGCGCCGCTACTACGATCTGGACGGGCTCTGGCACATGGCAGGGGAACTTGAACTGCCCGCGGCCATACGCACTC
CCCACGGAGAGAGCGAGTAG

Downstream 100 bases:

>100_bases
TCAGCCCTTTTCATGGCTTTGTGCGTGCCGATTCCCGGAACCTGGTTGTGTGTCTCGAACAGAGAGGATTTCCCATGAAA
CAACCGCTGCTGCTGCTGAT

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRLRVLWVGKSREEWVKQALADYATRIRRYAPLELVEVRDEKGAMAEEMRRRECERLEKQIPPGATLLLLDERGEQMDSP
GLAAYIGKQRDSGTADLVLVIGGAYGFSDAFRRRGRLLSLSPMTFTHQMVRVFLLEQLYRSFTILNNEPYHH

Sequences:

>Translated_152_residues
MRLRVLWVGKSREEWVKQALADYATRIRRYAPLELVEVRDEKGAMAEEMRRRECERLEKQIPPGATLLLLDERGEQMDSP
GLAAYIGKQRDSGTADLVLVIGGAYGFSDAFRRRGRLLSLSPMTFTHQMVRVFLLEQLYRSFTILNNEPYHH
>Mature_152_residues
MRLRVLWVGKSREEWVKQALADYATRIRRYAPLELVEVRDEKGAMAEEMRRRECERLEKQIPPGATLLLLDERGEQMDSP
GLAAYIGKQRDSGTADLVLVIGGAYGFSDAFRRRGRLLSLSPMTFTHQMVRVFLLEQLYRSFTILNNEPYHH

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=154, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_PELPD (A1AV33)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_903261.1
- ProteinModelPortal:   A1AV33
- SMR:   A1AV33
- STRING:   A1AV33
- GeneID:   4574540
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_3612
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- PhylomeDB:   A1AV33
- ProtClustDB:   CLSK829160
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 17627; Mature: 17627

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRVLWVGKSREEWVKQALADYATRIRRYAPLELVEVRDEKGAMAEEMRRRECERLEKQ
CEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHHHHHH
IPPGATLLLLDERGEQMDSPGLAAYIGKQRDSGTADLVLVIGGAYGFSDAFRRRGRLLSL
CCCCCEEEEECCCCCCCCCCCCEEHHCCCCCCCCCEEEEEEECCCCHHHHHHHCCCEEEE
SPMTFTHQMVRVFLLEQLYRSFTILNNEPYHH
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRLRVLWVGKSREEWVKQALADYATRIRRYAPLELVEVRDEKGAMAEEMRRRECERLEKQ
CEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHHHHHH
IPPGATLLLLDERGEQMDSPGLAAYIGKQRDSGTADLVLVIGGAYGFSDAFRRRGRLLSL
CCCCCEEEEECCCCCCCCCCCCEEHHCCCCCCCCCEEEEEEECCCCHHHHHHHCCCEEEE
SPMTFTHQMVRVFLLEQLYRSFTILNNEPYHH
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA