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The map label for this gene is typA [H]

Identifier: 118581906

GI number: 118581906

Start: 3876130

End: 3877935

Strand: Reverse

Name: typA [H]

Synonym: Ppro_3506

Alternate gene names: 118581906

Gene position: 3877935-3876130 (Counterclockwise)

Preceding gene: 118581907

Following gene: 118581905

Centisome position: 96.75

GC content: 61.46

Gene sequence:

>1806_bases
ATGCAGGAACGAATCAGAAACATCGCCATCATCGCCCACGTCGACCATGGCAAGACTACCCTGGTGGATGCAATGCTGCG
TCACGCCGGCGTTTTCCGCGAAAACGAGGCCATCACCGAGCGGGTCATGGACTCCAACGACCTGGAGAAGGAGCGCGGCA
TCACCATCCTGGCCAAGAGCCTCTCCATCCACCACGGCCGCTACAAGATCAATATCGTCGACACCCCCGGCCATGCCGAT
TTCGGCGGCGAGGTGGAGCGCGTGCTGAAGATGGTGGATTCGGTTCTGCTGCTGGTGGACGCCCTGGACGGTCCCATGCC
CCAGACCCGCTTCGTGCTGAAGAAATCGCTGGACCTGGGGCTCAAGCCGATCGTTGTCATCAACAAGATCGACCGCCCCG
GTTCCCGTCCTGACGAGGTGCTCAACATGGTCTTCGACCTGTTCTGCGAGCTGAACGCCTCCGACGAACAGCTTGACTTC
CCGGTGGTCTACACCAGCGCCAAGGTGGGCTATGCCAAGCTGGACATGGCCAGCGAATCCACCAGCATGGAGCCGCTCTT
CGCCGTTGTCGAGTCAAACGTACGCCCCCCCAAGGGGGATGCAACGGCACCCTTCCAGATGCTGATCGCCAACATCGATT
ACAACGACTACATCGGCCGCATGGCCACCGGCCGCATCTTCAACGGCAAGGTCAAATCCGGCGAGACCGTGGCCATGATC
AAGCGCGACGGTTCGATTACGAAAGGCCGCATTACCAAGCTTCTTGGTTACCAGGGGCTCAAGCAGGTGGAGATCGAGGA
GGCTGGTACCGGCGATATCGTTACTGTGGCCGGTTTCGAGGAGATCAGCATCGGTGAGACCCTGGCCTCGGCTGAAACTC
CCATCGCGGTCCCCTACGTCTCCATCGACGAGCCGACACTGGCCATGAACTTCATCGTCAACACCTCCCCCTTTGCCGGT
CGCGAGGGGAAATGGGTTACCTCGCGTAACATCCGCGAGCGCCTTACCAAGGAGTTGCGCACCAACGTCTCCCTCAGGGT
CGAGGACACCGACAGCCCGGACACCTTCAAGGTCTCCGGCCGCGGCGAACTGCACCTCTCCATCCTGATCGAGAACATGC
GGCGCGAGGGGTTCGAGCTGGCGGTCTCTAAGCCGGAGGTTATTACCCGCATCAAGGATGGCGTCAAGACCGAGCCTATG
GAATACCTGGTGGTGGATGTGGCCTCCGAATTCCAGGGCGCCATCATCGAAAAGATGGGACCGCGCAAGGGGGAGCTGGC
CGCCATGTCCCCCATGGGAGAGATGGTGCGCATGGAGTTCATCATCCCGGCCCGCGGCCTGATCGGGCTGCGCGGCGAAG
TTCTGACCGACACCCGCGGCACGGCGGTCATGACCCACACCTTCCACGAGTATGCTCCCTACAAGGGTGACATCCCGGGC
AGGAAGAACGGCGTTCTGATCGCCATGGAGCATGGCGAGACCACCGCCTACTCCCTGGATGCCCTGCAACCGCGTGGCAT
CCTGTTCATCGGTGCCGCCACAGAAGTCTATGGCGGCATGATCATCGGCCAGCACAGCAAGGACAACGACCTGGACGTCA
ACCCTTGCAAGGGTAAGAAGCTGACCAACGTGCGCGCCTCGGGAACCGACGACGCCATCAAGCTGACTCCGCCGCGCCTC
CTGACCCTGGAGCAGGCACTGGAGTTCATCGACGACGACGAGCTGGTGGAGGTGACGCCGCTCTCCATTCGCCTGCGCAA
GAAGGAGTTGGACCCCACCAAGCGTAAGCGCGCCACCAAGGGTTAG

Upstream 100 bases:

>100_bases
ATAAACGCTTGCCAGATCTGGAAAAAGCTGACATATTGCATACCGTACGACGGGCAGTAATGCCCGTCGTTTTATTTTGA
CTGATCGAGGAGTTTTACCC

Downstream 100 bases:

>100_bases
ATGGTGAGGGGTGAGGGGGGTGACCGCCTGTTTCGCCTCCCCCGGCCTCTCCGCTGATCGCCATAAAGAATTTTGAAACT
GATGCACAAAACGCCGTGGA

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MQERIRNIAIIAHVDHGKTTLVDAMLRHAGVFRENEAITERVMDSNDLEKERGITILAKSLSIHHGRYKINIVDTPGHAD
FGGEVERVLKMVDSVLLLVDALDGPMPQTRFVLKKSLDLGLKPIVVINKIDRPGSRPDEVLNMVFDLFCELNASDEQLDF
PVVYTSAKVGYAKLDMASESTSMEPLFAVVESNVRPPKGDATAPFQMLIANIDYNDYIGRMATGRIFNGKVKSGETVAMI
KRDGSITKGRITKLLGYQGLKQVEIEEAGTGDIVTVAGFEEISIGETLASAETPIAVPYVSIDEPTLAMNFIVNTSPFAG
REGKWVTSRNIRERLTKELRTNVSLRVEDTDSPDTFKVSGRGELHLSILIENMRREGFELAVSKPEVITRIKDGVKTEPM
EYLVVDVASEFQGAIIEKMGPRKGELAAMSPMGEMVRMEFIIPARGLIGLRGEVLTDTRGTAVMTHTFHEYAPYKGDIPG
RKNGVLIAMEHGETTAYSLDALQPRGILFIGAATEVYGGMIIGQHSKDNDLDVNPCKGKKLTNVRASGTDDAIKLTPPRL
LTLEQALEFIDDDELVEVTPLSIRLRKKELDPTKRKRATKG

Sequences:

>Translated_601_residues
MQERIRNIAIIAHVDHGKTTLVDAMLRHAGVFRENEAITERVMDSNDLEKERGITILAKSLSIHHGRYKINIVDTPGHAD
FGGEVERVLKMVDSVLLLVDALDGPMPQTRFVLKKSLDLGLKPIVVINKIDRPGSRPDEVLNMVFDLFCELNASDEQLDF
PVVYTSAKVGYAKLDMASESTSMEPLFAVVESNVRPPKGDATAPFQMLIANIDYNDYIGRMATGRIFNGKVKSGETVAMI
KRDGSITKGRITKLLGYQGLKQVEIEEAGTGDIVTVAGFEEISIGETLASAETPIAVPYVSIDEPTLAMNFIVNTSPFAG
REGKWVTSRNIRERLTKELRTNVSLRVEDTDSPDTFKVSGRGELHLSILIENMRREGFELAVSKPEVITRIKDGVKTEPM
EYLVVDVASEFQGAIIEKMGPRKGELAAMSPMGEMVRMEFIIPARGLIGLRGEVLTDTRGTAVMTHTFHEYAPYKGDIPG
RKNGVLIAMEHGETTAYSLDALQPRGILFIGAATEVYGGMIIGQHSKDNDLDVNPCKGKKLTNVRASGTDDAIKLTPPRL
LTLEQALEFIDDDELVEVTPLSIRLRKKELDPTKRKRATKG
>Mature_601_residues
MQERIRNIAIIAHVDHGKTTLVDAMLRHAGVFRENEAITERVMDSNDLEKERGITILAKSLSIHHGRYKINIVDTPGHAD
FGGEVERVLKMVDSVLLLVDALDGPMPQTRFVLKKSLDLGLKPIVVINKIDRPGSRPDEVLNMVFDLFCELNASDEQLDF
PVVYTSAKVGYAKLDMASESTSMEPLFAVVESNVRPPKGDATAPFQMLIANIDYNDYIGRMATGRIFNGKVKSGETVAMI
KRDGSITKGRITKLLGYQGLKQVEIEEAGTGDIVTVAGFEEISIGETLASAETPIAVPYVSIDEPTLAMNFIVNTSPFAG
REGKWVTSRNIRERLTKELRTNVSLRVEDTDSPDTFKVSGRGELHLSILIENMRREGFELAVSKPEVITRIKDGVKTEPM
EYLVVDVASEFQGAIIEKMGPRKGELAAMSPMGEMVRMEFIIPARGLIGLRGEVLTDTRGTAVMTHTFHEYAPYKGDIPG
RKNGVLIAMEHGETTAYSLDALQPRGILFIGAATEVYGGMIIGQHSKDNDLDVNPCKGKKLTNVRASGTDDAIKLTPPRL
LTLEQALEFIDDDELVEVTPLSIRLRKKELDPTKRKRATKG

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=242, Percent_Identity=34.7107438016529, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI94966754, Length=132, Percent_Identity=43.1818181818182, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI4503483, Length=144, Percent_Identity=36.1111111111111, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI18390331, Length=147, Percent_Identity=39.4557823129252, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI310132016, Length=110, Percent_Identity=40.9090909090909, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310110807, Length=110, Percent_Identity=40.9090909090909, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310123363, Length=110, Percent_Identity=40.9090909090909, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI25306283, Length=134, Percent_Identity=35.8208955223881, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI25306287, Length=134, Percent_Identity=35.8208955223881, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI19923640, Length=134, Percent_Identity=35.8208955223881, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI34147630, Length=250, Percent_Identity=28.8, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI94966752, Length=83, Percent_Identity=42.1686746987952, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI217272892, Length=140, Percent_Identity=33.5714285714286, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI217272894, Length=140, Percent_Identity=34.2857142857143, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI53729339, Length=152, Percent_Identity=32.8947368421053, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI53729337, Length=152, Percent_Identity=32.8947368421053, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI48994988, Length=603, Percent_Identity=57.2139303482587, Blast_Score=692, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=510, Percent_Identity=28.2352941176471, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789738, Length=153, Percent_Identity=35.9477124183007, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790412, Length=242, Percent_Identity=30.1652892561983, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789737, Length=242, Percent_Identity=30.1652892561983, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=31.7241379310345, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789559, Length=165, Percent_Identity=32.1212121212121, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17557151, Length=292, Percent_Identity=29.7945205479452, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71988811, Length=130, Percent_Identity=41.5384615384615, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71988819, Length=130, Percent_Identity=41.5384615384615, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17533571, Length=165, Percent_Identity=36.3636363636364, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17556745, Length=131, Percent_Identity=38.1679389312977, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17506493, Length=159, Percent_Identity=32.7044025157233, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17552882, Length=135, Percent_Identity=34.8148148148148, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17556456, Length=273, Percent_Identity=30.03663003663, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994658, Length=130, Percent_Identity=36.9230769230769, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323320, Length=513, Percent_Identity=26.9005847953216, Blast_Score=126, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6324707, Length=144, Percent_Identity=38.8888888888889, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6320593, Length=144, Percent_Identity=38.8888888888889, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322359, Length=149, Percent_Identity=39.5973154362416, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323098, Length=143, Percent_Identity=37.7622377622378, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=142, Percent_Identity=38.0281690140845, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324761, Length=271, Percent_Identity=28.0442804428044, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324550, Length=251, Percent_Identity=28.2868525896414, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI78706572, Length=520, Percent_Identity=25.9615384615385, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28574573, Length=140, Percent_Identity=39.2857142857143, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24582462, Length=147, Percent_Identity=40.8163265306122, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585711, Length=151, Percent_Identity=35.0993377483444, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585713, Length=151, Percent_Identity=35.0993377483444, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585709, Length=151, Percent_Identity=35.0993377483444, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=38.0597014925373, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI221458488, Length=164, Percent_Identity=37.8048780487805, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI281363316, Length=268, Percent_Identity=29.1044776119403, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17864358, Length=268, Percent_Identity=29.1044776119403, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19921738, Length=264, Percent_Identity=31.0606060606061, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28572034, Length=295, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 66274; Mature: 66274

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQERIRNIAIIAHVDHGKTTLVDAMLRHAGVFRENEAITERVMDSNDLEKERGITILAKS
CCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHCCEEEEEEE
LSIHHGRYKINIVDTPGHADFGGEVERVLKMVDSVLLLVDALDGPMPQTRFVLKKSLDLG
EEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
LKPIVVINKIDRPGSRPDEVLNMVFDLFCELNASDEQLDFPVVYTSAKVGYAKLDMASES
CCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCC
TSMEPLFAVVESNVRPPKGDATAPFQMLIANIDYNDYIGRMATGRIFNGKVKSGETVAMI
CCCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHCHHHCCCEECCCCCCCCEEEEE
KRDGSITKGRITKLLGYQGLKQVEIEEAGTGDIVTVAGFEEISIGETLASAETPIAVPYV
ECCCCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCCCCHHHHCCCCCEEEEEE
SIDEPTLAMNFIVNTSPFAGREGKWVTSRNIRERLTKELRTNVSLRVEDTDSPDTFKVSG
ECCCCCEEEEEEEECCCCCCCCCCEECHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECC
RGELHLSILIENMRREGFELAVSKPEVITRIKDGVKTEPMEYLVVDVASEFQGAIIEKMG
CCCEEEEEEEHHHHCCCEEEEECCHHHHHHHHCCCCCCCHHEEEEEHHHHHHHHHHHHCC
PRKGELAAMSPMGEMVRMEFIIPARGLIGLRGEVLTDTRGTAVMTHTFHEYAPYKGDIPG
CCCCCEEEECCCCHHEEEEEEECCCCCEECCCEEEECCCCCEEEEEEHHHHCCCCCCCCC
RKNGVLIAMEHGETTAYSLDALQPRGILFIGAATEVYGGMIIGQHSKDNDLDVNPCKGKK
CCCCEEEEEECCCCEEEEECCCCCCCEEEEEEHHHHHCCEEEECCCCCCCCCCCCCCCCE
LTNVRASGTDDAIKLTPPRLLTLEQALEFIDDDELVEVTPLSIRLRKKELDPTKRKRATK
ECEEECCCCCCEEEECCCHHEEHHHHHHHCCCCCEEEEECCEEEEECCCCCHHHHHCCCC
G
C
>Mature Secondary Structure
MQERIRNIAIIAHVDHGKTTLVDAMLRHAGVFRENEAITERVMDSNDLEKERGITILAKS
CCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHCCEEEEEEE
LSIHHGRYKINIVDTPGHADFGGEVERVLKMVDSVLLLVDALDGPMPQTRFVLKKSLDLG
EEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
LKPIVVINKIDRPGSRPDEVLNMVFDLFCELNASDEQLDFPVVYTSAKVGYAKLDMASES
CCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCC
TSMEPLFAVVESNVRPPKGDATAPFQMLIANIDYNDYIGRMATGRIFNGKVKSGETVAMI
CCCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHCHHHCCCEECCCCCCCCEEEEE
KRDGSITKGRITKLLGYQGLKQVEIEEAGTGDIVTVAGFEEISIGETLASAETPIAVPYV
ECCCCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCCCCHHHHCCCCCEEEEEE
SIDEPTLAMNFIVNTSPFAGREGKWVTSRNIRERLTKELRTNVSLRVEDTDSPDTFKVSG
ECCCCCEEEEEEEECCCCCCCCCCEECHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECC
RGELHLSILIENMRREGFELAVSKPEVITRIKDGVKTEPMEYLVVDVASEFQGAIIEKMG
CCCEEEEEEEHHHHCCCEEEEECCHHHHHHHHCCCCCCCHHEEEEEHHHHHHHHHHHHCC
PRKGELAAMSPMGEMVRMEFIIPARGLIGLRGEVLTDTRGTAVMTHTFHEYAPYKGDIPG
CCCCCEEEECCCCHHEEEEEEECCCCCEECCCEEEECCCCCEEEEEEHHHHCCCCCCCCC
RKNGVLIAMEHGETTAYSLDALQPRGILFIGAATEVYGGMIIGQHSKDNDLDVNPCKGKK
CCCCEEEEEECCCCEEEEECCCCCCCEEEEEEHHHHHCCEEEECCCCCCCCCCCCCCCCE
LTNVRASGTDDAIKLTPPRLLTLEQALEFIDDDELVEVTPLSIRLRKKELDPTKRKRATK
ECEEECCCCCCEEEECCCHHEEHHHHHHHCCCCCEEEEECCEEEEECCCCCHHHHHCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]