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The map label for this gene is murG

Identifier: 118581689

GI number: 118581689

Start: 3624716

End: 3625855

Strand: Reverse

Name: murG

Synonym: Ppro_3289

Alternate gene names: 118581689

Gene position: 3625855-3624716 (Counterclockwise)

Preceding gene: 118581690

Following gene: 118581688

Centisome position: 90.47

GC content: 66.58

Gene sequence:

>1140_bases
ATGAAGCTGATCATTGCCGGTGGCGGCACCGGCGGCCATCTCTTCCCCGGCATCGCCGTTGCCGAAGAGTTCCTCTCCCG
CGACCCGGCCAACCAGGTACTGTTCGTGGGCACCGAGCGGGGCATCGAGGCGCGTGCGGTTCCGGCAGCCGGCTTTCCCC
TTGAGCTGATCTCGGCAGCCGGCATCCGCGGCAAGGGAGGACTGGGCAAGCTGCGCGGGGCGGCGATGATGTTCAACGGC
TATCGCCAGTCATGCCGCCTTCTGGACCGCTTCCGGCCCGATGCCGTGCTGGGGGTGGGAGGCTATGCCTCGCTCCCCAT
GCTGCTGGCAGCCCGCACCAGGCAGGTGCCCAGCTTCATCCACGAGCAGAACGCCGTGCCGGGCATGACCAACCGGCTGC
TCTCCCGCTTTGCCGACCGGATCTTCATTACCCTGGAGGAGTCGTCCCGCTTCTTTGCCGGCAGGAGGACGCTTTTGACC
GGCAATCCCCTGCGGCGGCAGATCCTGGACCGGCTGGGGACCAGGGATCAGGGACCAGGGATCAGGGACCAGGAAAAACA
TATGACGGATTCTACCGGTCCCGCATCCCGGGTCCCCGGTCCCCGTTTCAACCTGCTAGTGTTCGGCGGCAGCCAGGGGG
CGCATGCCATCAACATGGCCATGGTGGCGGCCCTGCCGCTCCTCAAGCGCGCATCAGTCAGGCTCGGCATCACCCACCAG
ACCGGCGAAAGCGATCGTGAGCGTGTGGCAGCAGCCTACCGCTCTGCCGGGGTCGAGGCGCGGGTGCTGCCGTTCATCGC
CGACATGGCCAGTGAATACGCCCGGGCCGACCTGGTGGTCTGCCGGGCCGGCGCCACCACCATCGCCGAGGTCACGGCAC
TGGCCAAGGCCTGCCTGTTCATCCCCTTTCCCTATGCGGTGGATGATCACCAGCGCAGGAATGCCGAAGCGCTGCTCAGG
CAGTCGGCCTGCTTCATGCTGCTGGAACGGGAACTGTCGGCGGAGCGGCTGGCGGCCCTGATCCTGCAACTGGCAGGAGA
TCCGCGGCTGGTGCGGCGCACCGGAGAGCTGGCCTTCTCCATGGCCCGCCTTGATGCGGCCAGGATCATCGTTGACGAGA
TACTCACACCAACCAACTGA

Upstream 100 bases:

>100_bases
ACGGCGGCAGCTCGCTTTTGATCAGCCTGTTCGCCGTCGGTATTCTGCTCAATATCTCGTCCGGGCTGAAGATCACCCCC
ATCGGCCTGCCGGAGGGTCA

Downstream 100 bases:

>100_bases
AAAGGCATTCCCATGTACGGAAAAATCGAGAAAATCCACTTCGTCGGCATCGGCGGCATCGGCATGAGCGGCATCGCCGA
GGTGCTGCTGAATCTGGGCT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKLIIAGGGTGGHLFPGIAVAEEFLSRDPANQVLFVGTERGIEARAVPAAGFPLELISAAGIRGKGGLGKLRGAAMMFNG
YRQSCRLLDRFRPDAVLGVGGYASLPMLLAARTRQVPSFIHEQNAVPGMTNRLLSRFADRIFITLEESSRFFAGRRTLLT
GNPLRRQILDRLGTRDQGPGIRDQEKHMTDSTGPASRVPGPRFNLLVFGGSQGAHAINMAMVAALPLLKRASVRLGITHQ
TGESDRERVAAAYRSAGVEARVLPFIADMASEYARADLVVCRAGATTIAEVTALAKACLFIPFPYAVDDHQRRNAEALLR
QSACFMLLERELSAERLAALILQLAGDPRLVRRTGELAFSMARLDAARIIVDEILTPTN

Sequences:

>Translated_379_residues
MKLIIAGGGTGGHLFPGIAVAEEFLSRDPANQVLFVGTERGIEARAVPAAGFPLELISAAGIRGKGGLGKLRGAAMMFNG
YRQSCRLLDRFRPDAVLGVGGYASLPMLLAARTRQVPSFIHEQNAVPGMTNRLLSRFADRIFITLEESSRFFAGRRTLLT
GNPLRRQILDRLGTRDQGPGIRDQEKHMTDSTGPASRVPGPRFNLLVFGGSQGAHAINMAMVAALPLLKRASVRLGITHQ
TGESDRERVAAAYRSAGVEARVLPFIADMASEYARADLVVCRAGATTIAEVTALAKACLFIPFPYAVDDHQRRNAEALLR
QSACFMLLERELSAERLAALILQLAGDPRLVRRTGELAFSMARLDAARIIVDEILTPTN
>Mature_379_residues
MKLIIAGGGTGGHLFPGIAVAEEFLSRDPANQVLFVGTERGIEARAVPAAGFPLELISAAGIRGKGGLGKLRGAAMMFNG
YRQSCRLLDRFRPDAVLGVGGYASLPMLLAARTRQVPSFIHEQNAVPGMTNRLLSRFADRIFITLEESSRFFAGRRTLLT
GNPLRRQILDRLGTRDQGPGIRDQEKHMTDSTGPASRVPGPRFNLLVFGGSQGAHAINMAMVAALPLLKRASVRLGITHQ
TGESDRERVAAAYRSAGVEARVLPFIADMASEYARADLVVCRAGATTIAEVTALAKACLFIPFPYAVDDHQRRNAEALLR
QSACFMLLERELSAERLAALILQLAGDPRLVRRTGELAFSMARLDAARIIVDEILTPTN

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=344, Percent_Identity=34.0116279069767, Blast_Score=187, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_PELPD (A1AU61)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902939.1
- ProteinModelPortal:   A1AU61
- SMR:   A1AU61
- STRING:   A1AU61
- GeneID:   4572283
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_3289
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   A1AU61
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40970; Mature: 40970

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIIAGGGTGGHLFPGIAVAEEFLSRDPANQVLFVGTERGIEARAVPAAGFPLELISAA
CEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCCCCHHHHHHC
GIRGKGGLGKLRGAAMMFNGYRQSCRLLDRFRPDAVLGVGGYASLPMLLAARTRQVPSFI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
HEQNAVPGMTNRLLSRFADRIFITLEESSRFFAGRRTLLTGNPLRRQILDRLGTRDQGPG
HHCCCCCHHHHHHHHHHHHHEEEEEECCCCCHHCCEEEECCCHHHHHHHHHHCCCCCCCC
IRDQEKHMTDSTGPASRVPGPRFNLLVFGGSQGAHAINMAMVAALPLLKRASVRLGITHQ
CCCHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEEEEC
TGESDRERVAAAYRSAGVEARVLPFIADMASEYARADLVVCRAGATTIAEVTALAKACLF
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHH
IPFPYAVDDHQRRNAEALLRQSACFMLLERELSAERLAALILQLAGDPRLVRRTGELAFS
CCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MARLDAARIIVDEILTPTN
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLIIAGGGTGGHLFPGIAVAEEFLSRDPANQVLFVGTERGIEARAVPAAGFPLELISAA
CEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCCCCHHHHHHC
GIRGKGGLGKLRGAAMMFNGYRQSCRLLDRFRPDAVLGVGGYASLPMLLAARTRQVPSFI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
HEQNAVPGMTNRLLSRFADRIFITLEESSRFFAGRRTLLTGNPLRRQILDRLGTRDQGPG
HHCCCCCHHHHHHHHHHHHHEEEEEECCCCCHHCCEEEECCCHHHHHHHHHHCCCCCCCC
IRDQEKHMTDSTGPASRVPGPRFNLLVFGGSQGAHAINMAMVAALPLLKRASVRLGITHQ
CCCHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEEEEC
TGESDRERVAAAYRSAGVEARVLPFIADMASEYARADLVVCRAGATTIAEVTALAKACLF
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHH
IPFPYAVDDHQRRNAEALLRQSACFMLLERELSAERLAALILQLAGDPRLVRRTGELAFS
CCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MARLDAARIIVDEILTPTN
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA