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The map label for this gene is ychM [C]

Identifier: 118581680

GI number: 118581680

Start: 3613047

End: 3614819

Strand: Reverse

Name: ychM [C]

Synonym: Ppro_3280

Alternate gene names: 118581680

Gene position: 3614819-3613047 (Counterclockwise)

Preceding gene: 118581681

Following gene: 118581679

Centisome position: 90.19

GC content: 66.16

Gene sequence:

>1773_bases
ATGTCCCTGAACGCTCCGGAGACGGTCGCCACCCTGATCCGTAGCGTCCGTACGGTCAACGTGCGTCGCTGGCTGCCGGG
AGTGGCCGTGCTGCGGCGCTACGACCGGCACCTGCTTACGCGCGATCTGGCGGCGGGGGTGGTGCTGGCGGCACTGATGG
CGCCGGTGGGAATCGGCTATGCCGAAGCAGCCGGCCTGCCTCTTATCTGCGGCCTGTACGCCACCATCGTGCCGATGGTG
GCGTACGCACTCTTGGGGCCGAGCCGCATCCTGGTGCTGGGGCCGGATTCGGCACTTGCGGCGCTGGTGGGCGCCACGGT
CATCCCCCTGGCAGCGGGTGACGCCGGTCGCGCCGCGCTCCTTGCCGCGCTCTTGGCCCTCATGTCCGGCGTTCTCTGCG
TCCTGGCCGGCATCGCCCGCTTCGGGTTCATAACCGACCTGCTCTCCAAGCCGATCCGCTACGGATACATGAACGGTATC
GCCCTGACCCTGATGCTGGGGCAGCTCCCCAAGATCCTCGGTTTTTCGGTCAAGGGGGACAGTTTCCTGAGTCTGGCCGC
CGGCCTTACGCGTGGGGTGCGGGACAGGATGGTCAACCCCACCGCCTGTCTGGTTGGCCTCGCCTGCCTGGGGATCATGT
TCGGCGCTAAGCGCTGGTCCCCGCGCTTTCCCGGGGTCCTGGCAGCCCTGATCGCCGCCACCCTGGCCGTGACGCTGCTT
CCCCTGGCGCAGGTGGCGGTGGTGGGGGCCCTGCCCCAGGGGCTGCCGGCATTCCGCATTCCGGTATCCAGCCCCGCGGA
ATGGATTTCCCTCTGTGCCGGCGCCCTGGCTATCGCTTTGGTCAGCATCGCCGAGATGAGCGTGCTGTCGCGCATCTACG
CCCTGCGCGGCGGCTATTACGTGGATGACAACCAGGAACTGGTCGCCCTTGGCTTTGCCAACCTGGCCTGCGGCCTCTTC
CAGGGCTTTCCGGTGAGCTGCAGCGCCTCCCGCACACCGGTGGCGGAATCGGCCGGCGCCAGGACCCAGATGACCGGCGT
GGTGGGCGCGCTGCTCATCGCCCTGCTGCTGCTCTTCACTCCCGGTCTGATGCGACAGCTCCCCACGGCGGCCCTGGGGG
CGGTGGTTATCTTCGCCTGTAGTTCCATGGTTGAGGTCTCCGCGGTCAGACGGCTGTACGGAGTGCGGCGGGGAGAGTTC
TACCTCTCCCTGGTCTGTTTCCTGGGGGTGGTCTTTCTGGGGGTCATCCAGGGGATCTTCATCGCCGTGGGCATGGCGCT
TCTGGCTTTCATCTGGCGTGCCTGGCGTCCCTACTGCGCCGTCCTGGGGCGCATCGATGGCATGAAAGGGTACCACGACA
TAACCCGCCACCCCGAGGCGCGGCAGATTCCGGGGCTGGTGCTCTTCCGCTGGGATGCCCCCCTGTTCTTCGCCAACGCC
GAGATATTCCGCGAGCAGGCGCTCAGGGCGGTCTCCTGTGCCCCCACGCCCACCAGGTGGATTGTGGTGGCGGCCGAGCC
GGTTACCGATATTGATATCACGGCCGCCGACGTGCTGGCCGAACTGGATGACGAACTGGAGCGTTCAGGCATCGAGCTCT
GCTTTGCCCAGATGAAGGGGCCGGTCAAGGACCATCTCAAACGCTATGGCCTGTTTACCCAGCTGGGAACGAAAAATTTC
TTTCCCACCATCGGGCAGGCCGTGGACCGCTATGTGGACACATTCCACGTGGACTGGATCGACTGGGAGGATGTGGATCT
GCCGGTTGCCTGA

Upstream 100 bases:

>100_bases
CCCCACCCTGACGGCAGTGATGGCCGATGGCAGCGAGATGGTGATCATCGATGACGGAAACCTGCTGGTCTAGCATGGCG
AAGCGTCCCATTGACCGGGT

Downstream 100 bases:

>100_bases
GCCGGTAGTCCCACCCCCTCCTGGTCGAGCCGTCCCCCATACCCTCTCGGGAGTACCCATGAACGGACAACGTACCCTTT
CGCTCGGCTTTTCACCCTGC

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 589

Protein sequence:

>590_residues
MSLNAPETVATLIRSVRTVNVRRWLPGVAVLRRYDRHLLTRDLAAGVVLAALMAPVGIGYAEAAGLPLICGLYATIVPMV
AYALLGPSRILVLGPDSALAALVGATVIPLAAGDAGRAALLAALLALMSGVLCVLAGIARFGFITDLLSKPIRYGYMNGI
ALTLMLGQLPKILGFSVKGDSFLSLAAGLTRGVRDRMVNPTACLVGLACLGIMFGAKRWSPRFPGVLAALIAATLAVTLL
PLAQVAVVGALPQGLPAFRIPVSSPAEWISLCAGALAIALVSIAEMSVLSRIYALRGGYYVDDNQELVALGFANLACGLF
QGFPVSCSASRTPVAESAGARTQMTGVVGALLIALLLLFTPGLMRQLPTAALGAVVIFACSSMVEVSAVRRLYGVRRGEF
YLSLVCFLGVVFLGVIQGIFIAVGMALLAFIWRAWRPYCAVLGRIDGMKGYHDITRHPEARQIPGLVLFRWDAPLFFANA
EIFREQALRAVSCAPTPTRWIVVAAEPVTDIDITAADVLAELDDELERSGIELCFAQMKGPVKDHLKRYGLFTQLGTKNF
FPTIGQAVDRYVDTFHVDWIDWEDVDLPVA

Sequences:

>Translated_590_residues
MSLNAPETVATLIRSVRTVNVRRWLPGVAVLRRYDRHLLTRDLAAGVVLAALMAPVGIGYAEAAGLPLICGLYATIVPMV
AYALLGPSRILVLGPDSALAALVGATVIPLAAGDAGRAALLAALLALMSGVLCVLAGIARFGFITDLLSKPIRYGYMNGI
ALTLMLGQLPKILGFSVKGDSFLSLAAGLTRGVRDRMVNPTACLVGLACLGIMFGAKRWSPRFPGVLAALIAATLAVTLL
PLAQVAVVGALPQGLPAFRIPVSSPAEWISLCAGALAIALVSIAEMSVLSRIYALRGGYYVDDNQELVALGFANLACGLF
QGFPVSCSASRTPVAESAGARTQMTGVVGALLIALLLLFTPGLMRQLPTAALGAVVIFACSSMVEVSAVRRLYGVRRGEF
YLSLVCFLGVVFLGVIQGIFIAVGMALLAFIWRAWRPYCAVLGRIDGMKGYHDITRHPEARQIPGLVLFRWDAPLFFANA
EIFREQALRAVSCAPTPTRWIVVAAEPVTDIDITAADVLAELDDELERSGIELCFAQMKGPVKDHLKRYGLFTQLGTKNF
FPTIGQAVDRYVDTFHVDWIDWEDVDLPVA
>Mature_589_residues
SLNAPETVATLIRSVRTVNVRRWLPGVAVLRRYDRHLLTRDLAAGVVLAALMAPVGIGYAEAAGLPLICGLYATIVPMVA
YALLGPSRILVLGPDSALAALVGATVIPLAAGDAGRAALLAALLALMSGVLCVLAGIARFGFITDLLSKPIRYGYMNGIA
LTLMLGQLPKILGFSVKGDSFLSLAAGLTRGVRDRMVNPTACLVGLACLGIMFGAKRWSPRFPGVLAALIAATLAVTLLP
LAQVAVVGALPQGLPAFRIPVSSPAEWISLCAGALAIALVSIAEMSVLSRIYALRGGYYVDDNQELVALGFANLACGLFQ
GFPVSCSASRTPVAESAGARTQMTGVVGALLIALLLLFTPGLMRQLPTAALGAVVIFACSSMVEVSAVRRLYGVRRGEFY
LSLVCFLGVVFLGVIQGIFIAVGMALLAFIWRAWRPYCAVLGRIDGMKGYHDITRHPEARQIPGLVLFRWDAPLFFANAE
IFREQALRAVSCAPTPTRWIVVAAEPVTDIDITAADVLAELDDELERSGIELCFAQMKGPVKDHLKRYGLFTQLGTKNFF
PTIGQAVDRYVDTFHVDWIDWEDVDLPVA

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI39752683, Length=507, Percent_Identity=30.3747534516765, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI45827800, Length=507, Percent_Identity=30.3747534516765, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI94721259, Length=464, Percent_Identity=32.7586206896552, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI94721253, Length=465, Percent_Identity=32.4731182795699, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI94721255, Length=465, Percent_Identity=32.4731182795699, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI94721257, Length=465, Percent_Identity=32.4731182795699, Blast_Score=208, Evalue=9e-54,
Organism=Homo sapiens, GI269784651, Length=506, Percent_Identity=28.8537549407115, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI45827802, Length=459, Percent_Identity=30.2832244008715, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI4557535, Length=621, Percent_Identity=24.1545893719807, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI262206105, Length=584, Percent_Identity=28.2534246575343, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI262206075, Length=584, Percent_Identity=28.2534246575343, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI262206069, Length=584, Percent_Identity=28.2534246575343, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI262206063, Length=584, Percent_Identity=28.2534246575343, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI100913030, Length=564, Percent_Identity=24.822695035461, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI4505697, Length=505, Percent_Identity=25.5445544554455, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI47131207, Length=628, Percent_Identity=26.4331210191083, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI20336272, Length=628, Percent_Identity=26.4331210191083, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI16418413, Length=515, Percent_Identity=22.9126213592233, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI217272867, Length=515, Percent_Identity=22.9126213592233, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI65506789, Length=565, Percent_Identity=26.1946902654867, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI16418457, Length=501, Percent_Identity=23.1536926147705, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI301601599, Length=501, Percent_Identity=23.1536926147705, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI20336282, Length=518, Percent_Identity=22.2007722007722, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI16306483, Length=518, Percent_Identity=22.2007722007722, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI45827804, Length=264, Percent_Identity=26.8939393939394, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI301601602, Length=203, Percent_Identity=25.615763546798, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI87081859, Length=432, Percent_Identity=26.1574074074074, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI86564196, Length=623, Percent_Identity=25.5216693418941, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17562578, Length=610, Percent_Identity=26.0655737704918, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17551690, Length=595, Percent_Identity=24.8739495798319, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17566848, Length=597, Percent_Identity=23.9530988274707, Blast_Score=155, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI86564876, Length=579, Percent_Identity=24.5250431778929, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI86565215, Length=580, Percent_Identity=23.2758620689655, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI193203292, Length=567, Percent_Identity=23.1040564373898, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI86565209, Length=236, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI86565211, Length=236, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325260, Length=581, Percent_Identity=21.6867469879518, Blast_Score=134, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6323121, Length=471, Percent_Identity=23.3545647558386, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6319771, Length=470, Percent_Identity=22.9787234042553, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24649801, Length=571, Percent_Identity=25.3940455341506, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24666186, Length=550, Percent_Identity=26.5454545454545, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24651449, Length=587, Percent_Identity=24.7018739352641, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI19922482, Length=551, Percent_Identity=24.6823956442831, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI85815873, Length=535, Percent_Identity=24.8598130841122, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21358229, Length=554, Percent_Identity=22.2021660649819, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24647160, Length=439, Percent_Identity=23.9179954441913, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI21355087, Length=439, Percent_Identity=23.9179954441913, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21358633, Length=552, Percent_Identity=23.9130434782609, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24663084, Length=269, Percent_Identity=27.1375464684015, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21357695, Length=269, Percent_Identity=27.1375464684015, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 62851; Mature: 62720

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLNAPETVATLIRSVRTVNVRRWLPGVAVLRRYDRHLLTRDLAAGVVLAALMAPVGIGY
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AEAAGLPLICGLYATIVPMVAYALLGPSRILVLGPDSALAALVGATVIPLAAGDAGRAAL
HHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHH
LAALLALMSGVLCVLAGIARFGFITDLLSKPIRYGYMNGIALTLMLGQLPKILGFSVKGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SFLSLAAGLTRGVRDRMVNPTACLVGLACLGIMFGAKRWSPRFPGVLAALIAATLAVTLL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
PLAQVAVVGALPQGLPAFRIPVSSPAEWISLCAGALAIALVSIAEMSVLSRIYALRGGYY
HHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
VDDNQELVALGFANLACGLFQGFPVSCSASRTPVAESAGARTQMTGVVGALLIALLLLFT
ECCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHC
PGLMRQLPTAALGAVVIFACSSMVEVSAVRRLYGVRRGEFYLSLVCFLGVVFLGVIQGIF
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IAVGMALLAFIWRAWRPYCAVLGRIDGMKGYHDITRHPEARQIPGLVLFRWDAPLFFANA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCEEEEEECCCEEEHHH
EIFREQALRAVSCAPTPTRWIVVAAEPVTDIDITAADVLAELDDELERSGIELCFAQMKG
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PVKDHLKRYGLFTQLGTKNFFPTIGQAVDRYVDTFHVDWIDWEDVDLPVA
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]