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The map label for this gene is macB [H]

Identifier: 118581636

GI number: 118581636

Start: 3554282

End: 3555508

Strand: Direct

Name: macB [H]

Synonym: Ppro_3235

Alternate gene names: 118581636

Gene position: 3554282-3555508 (Clockwise)

Preceding gene: 118581635

Following gene: 118581637

Centisome position: 88.68

GC content: 63.98

Gene sequence:

>1227_bases
ATGAACTTCCCCCAAACCCTGAGAATAGCCCTGAGGGCGTTGCGCACCAACAAGATGCGCTCATTTTTGACCATGCTCGG
CATCATCATCGGCATCGCCGCCGTAATCGCCATGATGGCCGTGGGGTCGGGGGCCAGCTACGTCATTTCCCAGCAGATCG
CCAGCATCGGCAGCAACATCATCCTGGTCATCCCCGGCTCCACCACCAGCGGTGGCCTGCGCAGCGGCAGCGGCGGAGCC
CAGAGCCTGACCAGCGACGACGCCAAAGCCATCATCAACGAATGTCCCTCGGTGGAGACCGCCGCTCCCACGGTGCGCAG
CTCCGGCCTGGTGGTCTACGGCAACATGAACTGGTCGACCATCATCATGGGCGCCTCCCCGGAACTGTTCGACATCCGCG
AATGGTGGACCAGCAGCGGTCGCGGCATCACCCGGCAGGACGTGGACGGCGCCGCCAAGGTCTGCCTGCTGGGTCAGACG
GTGGCCGACAACCTGTTCGGCTCCGACGATCCCTTGGGCAAGATCGTGCGCATCAAGAAGATCCCTTTCACGGTGGTGGG
CGTCCTGGAACGCAAGGGGCAGTCGCCCCAGGGGACCGACCAGGACGACACCGTCTTCGTCCCGCTGCGCACGGCCCAAC
GCAACCTGGTTCGCTCCCCCTTTCCCAACACGGTGGGGGCGCTGCTGGTCAAGGCCAAGAGCGAGGATCTGCTGGAGCAG
GCCGAAGAGGAGGTTAACAGCCTGCTCAACCAGCGCCACCGCATCACCGGCGCCAAGGAACCTGACTTCTCCACCCGCAA
CCTGTCAGAAATCCTGGCAGTGGCCGAGCAGTCGTCGCGGGCCATGTCGCTGCTCCTGGGTACGGTGGCCTCCATCTCCC
TGGTGGTGGGAGGGATCGGCATCATGAACATCATGCTGGTCTCGGTAACGGAACGGACACGGGAGATCGGCATCCGCATG
GCCATCGGCGCCAGAAAGAGCGATATCCTGCTGCAGTTCATGACCGAGGCGGTACTTCTGACCATGATCGGCGGCATCGT
CGGCATCATGCTGGGCGCCGGCGGGGCCATGGTCGTCTCGCGCATCCTCTCCTGGCCCACGCTGATCTCCACCGGCTCCA
TCACCGTCGCCTTCCTCTTCTCGGGAGCCGTGGGGATCTTCTTCGGCTTCTACCCGGCCAGGAAGGCGGCCGGACTCAAC
CCCATCGAGGCACTCAGGTATGAATAG

Upstream 100 bases:

>100_bases
CATCATTATGGTCACCCACGAGAGCGACGTGGCCGCCCATGCTGGCCGCAGGATAACCTTCCGTGACGGCAGGATCATCG
CCGATACGAGGGGCTAGTGC

Downstream 100 bases:

>100_bases
CAGGCAGCAGGCGCCGGGGACGGCCATTTTCGAGCGCGAGTTCCCGGTGCTCTTTCACGAACTGGATTTCAACGGCACCC
TGGGGCCGGTGACCCTGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MNFPQTLRIALRALRTNKMRSFLTMLGIIIGIAAVIAMMAVGSGASYVISQQIASIGSNIILVIPGSTTSGGLRSGSGGA
QSLTSDDAKAIINECPSVETAAPTVRSSGLVVYGNMNWSTIIMGASPELFDIREWWTSSGRGITRQDVDGAAKVCLLGQT
VADNLFGSDDPLGKIVRIKKIPFTVVGVLERKGQSPQGTDQDDTVFVPLRTAQRNLVRSPFPNTVGALLVKAKSEDLLEQ
AEEEVNSLLNQRHRITGAKEPDFSTRNLSEILAVAEQSSRAMSLLLGTVASISLVVGGIGIMNIMLVSVTERTREIGIRM
AIGARKSDILLQFMTEAVLLTMIGGIVGIMLGAGGAMVVSRILSWPTLISTGSITVAFLFSGAVGIFFGFYPARKAAGLN
PIEALRYE

Sequences:

>Translated_408_residues
MNFPQTLRIALRALRTNKMRSFLTMLGIIIGIAAVIAMMAVGSGASYVISQQIASIGSNIILVIPGSTTSGGLRSGSGGA
QSLTSDDAKAIINECPSVETAAPTVRSSGLVVYGNMNWSTIIMGASPELFDIREWWTSSGRGITRQDVDGAAKVCLLGQT
VADNLFGSDDPLGKIVRIKKIPFTVVGVLERKGQSPQGTDQDDTVFVPLRTAQRNLVRSPFPNTVGALLVKAKSEDLLEQ
AEEEVNSLLNQRHRITGAKEPDFSTRNLSEILAVAEQSSRAMSLLLGTVASISLVVGGIGIMNIMLVSVTERTREIGIRM
AIGARKSDILLQFMTEAVLLTMIGGIVGIMLGAGGAMVVSRILSWPTLISTGSITVAFLFSGAVGIFFGFYPARKAAGLN
PIEALRYE
>Mature_408_residues
MNFPQTLRIALRALRTNKMRSFLTMLGIIIGIAAVIAMMAVGSGASYVISQQIASIGSNIILVIPGSTTSGGLRSGSGGA
QSLTSDDAKAIINECPSVETAAPTVRSSGLVVYGNMNWSTIIMGASPELFDIREWWTSSGRGITRQDVDGAAKVCLLGQT
VADNLFGSDDPLGKIVRIKKIPFTVVGVLERKGQSPQGTDQDDTVFVPLRTAQRNLVRSPFPNTVGALLVKAKSEDLLEQ
AEEEVNSLLNQRHRITGAKEPDFSTRNLSEILAVAEQSSRAMSLLLGTVASISLVVGGIGIMNIMLVSVTERTREIGIRM
AIGARKSDILLQFMTEAVLLTMIGGIVGIMLGAGGAMVVSRILSWPTLISTGSITVAFLFSGAVGIFFGFYPARKAAGLN
PIEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=408, Percent_Identity=39.7058823529412, Blast_Score=232, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43290; Mature: 43290

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPQTLRIALRALRTNKMRSFLTMLGIIIGIAAVIAMMAVGSGASYVISQQIASIGSNI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCE
ILVIPGSTTSGGLRSGSGGAQSLTSDDAKAIINECPSVETAAPTVRSSGLVVYGNMNWST
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEE
IIMGASPELFDIREWWTSSGRGITRQDVDGAAKVCLLGQTVADNLFGSDDPLGKIVRIKK
EEEECCCCHHHHHHHHCCCCCCCCHHCCCHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEC
IPFTVVGVLERKGQSPQGTDQDDTVFVPLRTAQRNLVRSPFPNTVGALLVKAKSEDLLEQ
CCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCHHHHHHEECCHHHHHHH
AEEEVNSLLNQRHRITGAKEPDFSTRNLSEILAVAEQSSRAMSLLLGTVASISLVVGGIG
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMNIMLVSVTERTREIGIRMAIGARKSDILLQFMTEAVLLTMIGGIVGIMLGAGGAMVVS
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RILSWPTLISTGSITVAFLFSGAVGIFFGFYPARKAAGLNPIEALRYE
HHHCCCHHEECCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
>Mature Secondary Structure
MNFPQTLRIALRALRTNKMRSFLTMLGIIIGIAAVIAMMAVGSGASYVISQQIASIGSNI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCE
ILVIPGSTTSGGLRSGSGGAQSLTSDDAKAIINECPSVETAAPTVRSSGLVVYGNMNWST
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEE
IIMGASPELFDIREWWTSSGRGITRQDVDGAAKVCLLGQTVADNLFGSDDPLGKIVRIKK
EEEECCCCHHHHHHHHCCCCCCCCHHCCCHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEC
IPFTVVGVLERKGQSPQGTDQDDTVFVPLRTAQRNLVRSPFPNTVGALLVKAKSEDLLEQ
CCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCHHHHHHEECCHHHHHHH
AEEEVNSLLNQRHRITGAKEPDFSTRNLSEILAVAEQSSRAMSLLLGTVASISLVVGGIG
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMNIMLVSVTERTREIGIRMAIGARKSDILLQFMTEAVLLTMIGGIVGIMLGAGGAMVVS
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RILSWPTLISTGSITVAFLFSGAVGIFFGFYPARKAAGLNPIEALRYE
HHHCCCHHEECCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA