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The map label for this gene is intZ [H]

Identifier: 118581522

GI number: 118581522

Start: 3423803

End: 3425152

Strand: Direct

Name: intZ [H]

Synonym: Ppro_3121

Alternate gene names: 118581522

Gene position: 3423803-3425152 (Clockwise)

Preceding gene: 118581521

Following gene: 118581523

Centisome position: 85.42

GC content: 55.19

Gene sequence:

>1350_bases
GTGTCTGACTACCTGGAGGACGCCATGAAAAAAACGACCTTCACCGACACCATGATTCGGAAACTGAAACCAACGGAATC
CGATTACACCCGGAGCGAGGGAAACGGCTTCACCATCCGCGTCATGCCCTCCGGTTCAAAAACATGGCTGTACCTCTATG
CCTTCGACGGTAAGCGCCGGAAGATGAACCTGGGGAGTTATCCAGACGTAACCCTGGAAACAGCACGGGGGCGATTTGAG
GACGCCAAACGGAAGGTGAAGAACAACATTGATCCCATGGCGGAAGCCGAAGAACAAGCGGAAGAGCGGCGAAAGGCCCC
CACAGTTGCCGACCTTGTGCATGATTACATCGAGCGCCACGCCAAACGATTCAAGCGGTCATGGGCGAAGGATGAGCAGA
TCCTTAATCGGGAGGTTGTTCCAGCCTGGGGAAAGCGTAAAGCTGCCGATGTTACCAAACGGGACATACTCAGACTGCTT
GAAGAGATCGTGAACCGCAACGCCCCCGCCATGGCGAACAACACCTTTCAGATCATCCGCAAGATGTTCAACTGGGCCGT
TGAGCAGGACATTCTCCAGCACACCCCCTGCACCGGCGTCAAGCTCCCCTCCCCTAAGCTCTCCCGCGACCGTGTGCTTT
CAGAGTCCGAAATCAAGACGCTATGGGAAAACCTTGGCCGTCCAGACGCGGGTATGTCGGACGGAGTACGCCGAGCGCTG
CGCCTGATCCTGACAACAGCACAACGCCCCGGTGAAGTGACCGGACTGCATACCAGCGAACTTGACGGCTGCTGGTGGAC
CATTCCGGCAGAACGCGCAAAGAACGGCAAGACTCACCGAGTCTACCTGTCTGGCCTTGCTCTGGAGATCATCAACCAAG
CCATAGCTCAAGCCAAGAAATCAAGAGAAACACCATATGACCAGGAATACAACGGTTACGTCTTTCCATGCCACCACAAG
AGCAAGGAGAAGCCCATGGGTGACACTGCCCTTGCCGTTGCCGTAGGCCGCGCCCTCGCATCTCCACTAACAGACGATAA
AGGCAACCCCCTCTTTACAGCAGCCGGCAAACCAGCCACCGAGAACCGACTTGGAATAGATCACTTCACCCCGCACGATC
TGAGACGCACAACAGCCACCTTCATGGCGAGCATGGGCTTTATGGATGAAGTGATCGATGCAGTCCTGAACCACGCAAAG
CAAGGCGTCATAAAGGTCTATAATCAGTATCGCTATGACGTGGAAAAACAGCAGGCTCTTGAAACTTGGGAGAACAAGCT
GAAAACCATCCTGGCCGGTGACAAGGTCGTCGACCTGGACCAGAAACGCAAGGAACGGAACGTCGCTTGA

Upstream 100 bases:

>100_bases
CCACATATTAAGCGTATTTCTCAATTCATAGTGTTTCAAACTATATCACCCTAACGCAGCAAACTATTACACCACTACTA
CACCACAGGCCAACAACAAT

Downstream 100 bases:

>100_bases
CGCTCTGTAGCTTATAGGCTAACATATGACCATCCAGACATATCCGCATGAAATCGAATACTATGTCACCGAGACAGGAA
GTAAGCCGTTCAAGGTGTGG

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSDYLEDAMKKTTFTDTMIRKLKPTESDYTRSEGNGFTIRVMPSGSKTWLYLYAFDGKRRKMNLGSYPDVTLETARGRFE
DAKRKVKNNIDPMAEAEEQAEERRKAPTVADLVHDYIERHAKRFKRSWAKDEQILNREVVPAWGKRKAADVTKRDILRLL
EEIVNRNAPAMANNTFQIIRKMFNWAVEQDILQHTPCTGVKLPSPKLSRDRVLSESEIKTLWENLGRPDAGMSDGVRRAL
RLILTTAQRPGEVTGLHTSELDGCWWTIPAERAKNGKTHRVYLSGLALEIINQAIAQAKKSRETPYDQEYNGYVFPCHHK
SKEKPMGDTALAVAVGRALASPLTDDKGNPLFTAAGKPATENRLGIDHFTPHDLRRTTATFMASMGFMDEVIDAVLNHAK
QGVIKVYNQYRYDVEKQQALETWENKLKTILAGDKVVDLDQKRKERNVA

Sequences:

>Translated_449_residues
MSDYLEDAMKKTTFTDTMIRKLKPTESDYTRSEGNGFTIRVMPSGSKTWLYLYAFDGKRRKMNLGSYPDVTLETARGRFE
DAKRKVKNNIDPMAEAEEQAEERRKAPTVADLVHDYIERHAKRFKRSWAKDEQILNREVVPAWGKRKAADVTKRDILRLL
EEIVNRNAPAMANNTFQIIRKMFNWAVEQDILQHTPCTGVKLPSPKLSRDRVLSESEIKTLWENLGRPDAGMSDGVRRAL
RLILTTAQRPGEVTGLHTSELDGCWWTIPAERAKNGKTHRVYLSGLALEIINQAIAQAKKSRETPYDQEYNGYVFPCHHK
SKEKPMGDTALAVAVGRALASPLTDDKGNPLFTAAGKPATENRLGIDHFTPHDLRRTTATFMASMGFMDEVIDAVLNHAK
QGVIKVYNQYRYDVEKQQALETWENKLKTILAGDKVVDLDQKRKERNVA
>Mature_448_residues
SDYLEDAMKKTTFTDTMIRKLKPTESDYTRSEGNGFTIRVMPSGSKTWLYLYAFDGKRRKMNLGSYPDVTLETARGRFED
AKRKVKNNIDPMAEAEEQAEERRKAPTVADLVHDYIERHAKRFKRSWAKDEQILNREVVPAWGKRKAADVTKRDILRLLE
EIVNRNAPAMANNTFQIIRKMFNWAVEQDILQHTPCTGVKLPSPKLSRDRVLSESEIKTLWENLGRPDAGMSDGVRRALR
LILTTAQRPGEVTGLHTSELDGCWWTIPAERAKNGKTHRVYLSGLALEIINQAIAQAKKSRETPYDQEYNGYVFPCHHKS
KEKPMGDTALAVAVGRALASPLTDDKGNPLFTAAGKPATENRLGIDHFTPHDLRRTTATFMASMGFMDEVIDAVLNHAKQ
GVIKVYNQYRYDVEKQQALETWENKLKTILAGDKVVDLDQKRKERNVA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=445, Percent_Identity=26.2921348314607, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1788974, Length=442, Percent_Identity=25.1131221719457, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788690, Length=435, Percent_Identity=20.6896551724138, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 51108; Mature: 50977

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYLEDAMKKTTFTDTMIRKLKPTESDYTRSEGNGFTIRVMPSGSKTWLYLYAFDGKRR
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCC
KMNLGSYPDVTLETARGRFEDAKRKVKNNIDPMAEAEEQAEERRKAPTVADLVHDYIERH
CCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AKRFKRSWAKDEQILNREVVPAWGKRKAADVTKRDILRLLEEIVNRNAPAMANNTFQIIR
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
KMFNWAVEQDILQHTPCTGVKLPSPKLSRDRVLSESEIKTLWENLGRPDAGMSDGVRRAL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHH
RLILTTAQRPGEVTGLHTSELDGCWWTIPAERAKNGKTHRVYLSGLALEIINQAIAQAKK
HHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHH
SRETPYDQEYNGYVFPCHHKSKEKPMGDTALAVAVGRALASPLTDDKGNPLFTAAGKPAT
HCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
ENRLGIDHFTPHDLRRTTATFMASMGFMDEVIDAVLNHAKQGVIKVYNQYRYDVEKQQAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ETWENKLKTILAGDKVVDLDQKRKERNVA
HHHHHHHHHHHCCCCEECCHHHHHHCCCC
>Mature Secondary Structure 
SDYLEDAMKKTTFTDTMIRKLKPTESDYTRSEGNGFTIRVMPSGSKTWLYLYAFDGKRR
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCC
KMNLGSYPDVTLETARGRFEDAKRKVKNNIDPMAEAEEQAEERRKAPTVADLVHDYIERH
CCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AKRFKRSWAKDEQILNREVVPAWGKRKAADVTKRDILRLLEEIVNRNAPAMANNTFQIIR
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
KMFNWAVEQDILQHTPCTGVKLPSPKLSRDRVLSESEIKTLWENLGRPDAGMSDGVRRAL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHH
RLILTTAQRPGEVTGLHTSELDGCWWTIPAERAKNGKTHRVYLSGLALEIINQAIAQAKK
HHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHH
SRETPYDQEYNGYVFPCHHKSKEKPMGDTALAVAVGRALASPLTDDKGNPLFTAAGKPAT
HCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
ENRLGIDHFTPHDLRRTTATFMASMGFMDEVIDAVLNHAKQGVIKVYNQYRYDVEKQQAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ETWENKLKTILAGDKVVDLDQKRKERNVA
HHHHHHHHHHHCCCCEECCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]