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The map label for this gene is argC

Identifier: 118581483

GI number: 118581483

Start: 3369424

End: 3370464

Strand: Reverse

Name: argC

Synonym: Ppro_3080

Alternate gene names: 118581483

Gene position: 3370464-3369424 (Counterclockwise)

Preceding gene: 118581485

Following gene: 118581478

Centisome position: 84.09

GC content: 62.54

Gene sequence:

>1041_bases
ATGCTTAACGTAGCAATCGTCGGAGCCAGCGGTTATACCGGCCTGGAACTGCTCCGTATCCTCTACGCCCATCCGCAGGT
TGCGGTGACCTGCGTAACTTCGGAGCGGAGCGCCGGGAAGCGTATCGACGAGGTCTTTCCCACCCTGAGGGATCGTTGCA
GCCTGGTGCTGGAGAATCTGGAGCCGGTGCGGGTCTCCCAGAAGGCCGACCTGATCTTCACGGCACTGCCCCACAAGGCG
GCCATGGCTGTGATGCCTACCTTCATGGAGTTGGGCAAGACGGTCATCGACCTGTCGGCCGATTACCGCCTCAGCGATGC
CGAGGTCTACGGTGCCTGGTACGAGCCGCACCTGAATCCCGAATTGCTGAAGAGCGCCGTGTACGGCCTGCCCGAGATCA
GGCGGGAGAGCATTCGCGGGAAGAAGCTGGTGGCCAACCCCGGTTGCTACCCCACCAGCATCACCCTGGGACTGGCGCCG
CTGCTGAAAAACGGCATGATCGATCTGAAGAGCATCATCGCCGATTCCGCCTCGGGAGTGACCGGCGCGGGACGGGGAGC
CAAGGTGGATTCGCTGTACTGCGAGGTGAACGAGGGATACAAGGCCTACGGCGTGGGTGGCGTGCATCGCCACACTCCCG
AGATCGAGCAGGAACTGTCCCTGCTTGCCGGGGAAAAGGTGACCCTCACCTTCACTCCCCATCTGGTGCCCATGGACCGG
GGCATCCTTTCCACCATCTATGCCACCCCCCTGAAGGGTGTCACCACCGAGGAGCTGAACGAGTTGTACCGCAACTTCTA
CGCCGAGGAGCCGTTCGTGCGGGTGCTGCCCCTGGGCAGCCTCCCCTCCACCGCCTTCGTGCGCGGGTCCAATTTCTGCG
ACATAGCGCCGGTTGTGGACAAGCGCACCGGCAGGGTCATCGTCGTATCGGCCATCGACAATCTGATGAAGGGGGCCTCC
GGTCAGGCGGTGCAGAACATGAATATCGTCTGCGGCTTCTATGAATCCGCCGGCCTGAGCGGATTGGCGCTCTTCCCCTG
A

Upstream 100 bases:

>100_bases
GCCACATGGTCTACGCTCTCCACCGTACCGTCCCCCCCGCTCGTTCGTCGGCTGCTGACGGTCGTTGTATCCCATATCCA
CGAATCAGGAGGTCGTTTTC

Downstream 100 bases:

>100_bases
TTTCCGGGGGATGCCACGCGCGTCGTGAACATCGCGGGGCTGGCCGTCTTGACGGTCAGCCCCGTTTCAGTTCTATCTCC
AGATCGTGGATCTTCTTGCG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MLNVAIVGASGYTGLELLRILYAHPQVAVTCVTSERSAGKRIDEVFPTLRDRCSLVLENLEPVRVSQKADLIFTALPHKA
AMAVMPTFMELGKTVIDLSADYRLSDAEVYGAWYEPHLNPELLKSAVYGLPEIRRESIRGKKLVANPGCYPTSITLGLAP
LLKNGMIDLKSIIADSASGVTGAGRGAKVDSLYCEVNEGYKAYGVGGVHRHTPEIEQELSLLAGEKVTLTFTPHLVPMDR
GILSTIYATPLKGVTTEELNELYRNFYAEEPFVRVLPLGSLPSTAFVRGSNFCDIAPVVDKRTGRVIVVSAIDNLMKGAS
GQAVQNMNIVCGFYESAGLSGLALFP

Sequences:

>Translated_346_residues
MLNVAIVGASGYTGLELLRILYAHPQVAVTCVTSERSAGKRIDEVFPTLRDRCSLVLENLEPVRVSQKADLIFTALPHKA
AMAVMPTFMELGKTVIDLSADYRLSDAEVYGAWYEPHLNPELLKSAVYGLPEIRRESIRGKKLVANPGCYPTSITLGLAP
LLKNGMIDLKSIIADSASGVTGAGRGAKVDSLYCEVNEGYKAYGVGGVHRHTPEIEQELSLLAGEKVTLTFTPHLVPMDR
GILSTIYATPLKGVTTEELNELYRNFYAEEPFVRVLPLGSLPSTAFVRGSNFCDIAPVVDKRTGRVIVVSAIDNLMKGAS
GQAVQNMNIVCGFYESAGLSGLALFP
>Mature_346_residues
MLNVAIVGASGYTGLELLRILYAHPQVAVTCVTSERSAGKRIDEVFPTLRDRCSLVLENLEPVRVSQKADLIFTALPHKA
AMAVMPTFMELGKTVIDLSADYRLSDAEVYGAWYEPHLNPELLKSAVYGLPEIRRESIRGKKLVANPGCYPTSITLGLAP
LLKNGMIDLKSIIADSASGVTGAGRGAKVDSLYCEVNEGYKAYGVGGVHRHTPEIEQELSLLAGEKVTLTFTPHLVPMDR
GILSTIYATPLKGVTTEELNELYRNFYAEEPFVRVLPLGSLPSTAFVRGSNFCDIAPVVDKRTGRVIVVSAIDNLMKGAS
GQAVQNMNIVCGFYESAGLSGLALFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=345, Percent_Identity=38.5507246376812, Blast_Score=208, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6320913, Length=345, Percent_Identity=31.0144927536232, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_PELPD (A1ATK5)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902733.1
- ProteinModelPortal:   A1ATK5
- SMR:   A1ATK5
- STRING:   A1ATK5
- GeneID:   4573985
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_3080
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   A1ATK5
- ProtClustDB:   PRK00436
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37393; Mature: 37393

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNVAIVGASGYTGLELLRILYAHPQVAVTCVTSERSAGKRIDEVFPTLRDRCSLVLENL
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
EPVRVSQKADLIFTALPHKAAMAVMPTFMELGKTVIDLSADYRLSDAEVYGAWYEPHLNP
CCEEECCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCEECCCEEEEEECCCCCCH
ELLKSAVYGLPEIRRESIRGKKLVANPGCYPTSITLGLAPLLKNGMIDLKSIIADSASGV
HHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCC
TGAGRGAKVDSLYCEVNEGYKAYGVGGVHRHTPEIEQELSLLAGEKVTLTFTPHLVPMDR
CCCCCCCEEEEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCC
GILSTIYATPLKGVTTEELNELYRNFYAEEPFVRVLPLGSLPSTAFVRGSNFCDIAPVVD
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCEEECHHCC
KRTGRVIVVSAIDNLMKGASGQAVQNMNIVCGFYESAGLSGLALFP
CCCCCEEEEEHHHHHHCCCCCCEEECCEEEEEEHHCCCCCEEECCC
>Mature Secondary Structure
MLNVAIVGASGYTGLELLRILYAHPQVAVTCVTSERSAGKRIDEVFPTLRDRCSLVLENL
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
EPVRVSQKADLIFTALPHKAAMAVMPTFMELGKTVIDLSADYRLSDAEVYGAWYEPHLNP
CCEEECCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCEECCCEEEEEECCCCCCH
ELLKSAVYGLPEIRRESIRGKKLVANPGCYPTSITLGLAPLLKNGMIDLKSIIADSASGV
HHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCC
TGAGRGAKVDSLYCEVNEGYKAYGVGGVHRHTPEIEQELSLLAGEKVTLTFTPHLVPMDR
CCCCCCCEEEEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCC
GILSTIYATPLKGVTTEELNELYRNFYAEEPFVRVLPLGSLPSTAFVRGSNFCDIAPVVD
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCEEECHHCC
KRTGRVIVVSAIDNLMKGASGQAVQNMNIVCGFYESAGLSGLALFP
CCCCCEEEEEHHHHHHCCCCCCEEECCEEEEEEHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA