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The map label for this gene is ntrC [H]

Identifier: 118581482

GI number: 118581482

Start: 3367926

End: 3369368

Strand: Direct

Name: ntrC [H]

Synonym: Ppro_3079

Alternate gene names: 118581482

Gene position: 3367926-3369368 (Clockwise)

Preceding gene: 118581481

Following gene: 118581484

Centisome position: 84.03

GC content: 62.23

Gene sequence:

>1443_bases
ATGACACTTACCAGAATCCTGGTGGCCGACGACGAAGAGAGCATGCGCTGGGTTCTTTCCAAGGCCCTGAAGAGGAAGGG
CTTCACCGTCGACCTTGCCGACGACGGCCGACAGGCCCTGGCGCTGATCCAGGAGAACAGCTACGACCTGGCCATCCTGG
ACATCAAGATGCCCGGCATGAGCGGCCTCGATCTGCTGGACCGCATCCGCGAGATGAAGAGCGACCTGCTGGTGGTGATC
ATGACCGCCGAGGCCAGCATGAAGAACGCCGTGGAGGCCATGAAGCGCGGTGCCTACGACTACATCACCAAGCCCTTCGA
CCTGGACGTCATCGACGCCATCGTGGAAAAGGTCGGGCGGGCGCGGGAGATAGCCGGCCAGGTGTCCCTGCTCAAGCAGG
AGCTGAAGGAACACTACCAGGTGGAGAAGAACATCATCGGCAACTCGGCCGCCATGCAGAGTATCTACAAGACCATTGGC
AAAGTGGCTGACAGCGACATTACCATCCTGATCCAGGGAGAGTCGGGCACCGGCAAGGAGATGGTGGCCCGGGCCATACA
TTTCAACTCAGGCCGACTGGGCAAGCCATTCGTGGCCATCAACTGCGCCGCCATTCCCCGCGACCTCCTGGAGAGCGAGC
TGTTCGGCTCGGAGAGGGGTGCCTTCACCGGGGCCAGCGAGCGCAAGCAGGGCAAATTCGAGCAGGCCAACCAGGGGACG
ATCTTCTTGGACGAGATCGGCGACATGCCGCTGGACCTGCAGGCCAAGATCCTGCGCGTGCTCCAGGAGCACGAGGTTAC
CCGGGTGGGCGGAACCCAGAGCATAGCGGTGAACGTGCGCATCGTTGCCGCCACCAATCAGGAGTTGCAGGAGCGGGTCC
GCCAGCGGGAGTTCCGCGAGGACCTGTACTACCGCCTGAACGTGGTCCCCATCACCCTGGCCCCTTTGCGGGAGCGGCGC
GACGACATCCCGGAGCTGGTGCGCTACTTTCTGGACCGGACCTGCACGGAGCTCTCCATACCGCCCAAGCAGCTCACCCC
CGAAGCTATGGCCCTGCTGTCCAGGCATTCCTGGCCAGGCAACGTGCGTGAGCTGGAGAACACCATCAAGCGCGCCGTGA
TCCTCTCCAACGACCCCATGCTGACCGAGGCCGATTTCGACGGCCTGCAACCGGAGGGGGAGGAGACGGCAATGACTCCA
CAGGATGCCTCGCTGGAGGCCATAGTGGAGGCAAAGCTGAGGAGTTGCCTGACTGGCATCGAAAAGCTGGACAAGAGCGA
CATCCACGCCAAGGTGCTGCAGCAGGTGGAACGCCCCCTGATCCGCTTTATCCTGGAAAAGACGCGCTGGAACCAGGTCA
AGGCGGCCGACATCCTGGGCATCAACCGCAACACCCTGCGCAAGAAGATCCACGATCTGGAGATAGAACTGAAACGGGGC
TGA

Upstream 100 bases:

>100_bases
CACGGTTCTGCTGCCGCTGGTGCAGTAGAGGCTGTTCAATGTTCCCGGTTTCAATTCTGAACCCTGAACCAACATACCGA
ATTCCCACGAGGTTATACAT

Downstream 100 bases:

>100_bases
CCGTCAAGACGGCCAGCCCCGCGATGTTCACGACGCGCGTGGCATCCCCCGGAAATCAGGGGAAGAGCGCCAATCCGCTC
AGGCCGGCGGATTCATAGAA

Product: two component sigma54 specific Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTLTRILVADDEESMRWVLSKALKRKGFTVDLADDGRQALALIQENSYDLAILDIKMPGMSGLDLLDRIREMKSDLLVVI
MTAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIVEKVGRAREIAGQVSLLKQELKEHYQVEKNIIGNSAAMQSIYKTIG
KVADSDITILIQGESGTGKEMVARAIHFNSGRLGKPFVAINCAAIPRDLLESELFGSERGAFTGASERKQGKFEQANQGT
IFLDEIGDMPLDLQAKILRVLQEHEVTRVGGTQSIAVNVRIVAATNQELQERVRQREFREDLYYRLNVVPITLAPLRERR
DDIPELVRYFLDRTCTELSIPPKQLTPEAMALLSRHSWPGNVRELENTIKRAVILSNDPMLTEADFDGLQPEGEETAMTP
QDASLEAIVEAKLRSCLTGIEKLDKSDIHAKVLQQVERPLIRFILEKTRWNQVKAADILGINRNTLRKKIHDLEIELKRG

Sequences:

>Translated_480_residues
MTLTRILVADDEESMRWVLSKALKRKGFTVDLADDGRQALALIQENSYDLAILDIKMPGMSGLDLLDRIREMKSDLLVVI
MTAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIVEKVGRAREIAGQVSLLKQELKEHYQVEKNIIGNSAAMQSIYKTIG
KVADSDITILIQGESGTGKEMVARAIHFNSGRLGKPFVAINCAAIPRDLLESELFGSERGAFTGASERKQGKFEQANQGT
IFLDEIGDMPLDLQAKILRVLQEHEVTRVGGTQSIAVNVRIVAATNQELQERVRQREFREDLYYRLNVVPITLAPLRERR
DDIPELVRYFLDRTCTELSIPPKQLTPEAMALLSRHSWPGNVRELENTIKRAVILSNDPMLTEADFDGLQPEGEETAMTP
QDASLEAIVEAKLRSCLTGIEKLDKSDIHAKVLQQVERPLIRFILEKTRWNQVKAADILGINRNTLRKKIHDLEIELKRG
>Mature_479_residues
TLTRILVADDEESMRWVLSKALKRKGFTVDLADDGRQALALIQENSYDLAILDIKMPGMSGLDLLDRIREMKSDLLVVIM
TAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIVEKVGRAREIAGQVSLLKQELKEHYQVEKNIIGNSAAMQSIYKTIGK
VADSDITILIQGESGTGKEMVARAIHFNSGRLGKPFVAINCAAIPRDLLESELFGSERGAFTGASERKQGKFEQANQGTI
FLDEIGDMPLDLQAKILRVLQEHEVTRVGGTQSIAVNVRIVAATNQELQERVRQREFREDLYYRLNVVPITLAPLRERRD
DIPELVRYFLDRTCTELSIPPKQLTPEAMALLSRHSWPGNVRELENTIKRAVILSNDPMLTEADFDGLQPEGEETAMTPQ
DASLEAIVEAKLRSCLTGIEKLDKSDIHAKVLQQVERPLIRFILEKTRWNQVKAADILGINRNTLRKKIHDLEIELKRG

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=474, Percent_Identity=42.8270042194093, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1790299, Length=479, Percent_Identity=43.2150313152401, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1790437, Length=465, Percent_Identity=42.7956989247312, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1788905, Length=472, Percent_Identity=36.864406779661, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI1789087, Length=264, Percent_Identity=52.6515151515151, Blast_Score=264, Evalue=8e-72,
Organism=Escherichia coli, GI87082117, Length=276, Percent_Identity=48.9130434782609, Blast_Score=264, Evalue=9e-72,
Organism=Escherichia coli, GI1789233, Length=335, Percent_Identity=43.8805970149254, Blast_Score=254, Evalue=6e-69,
Organism=Escherichia coli, GI87082152, Length=286, Percent_Identity=45.1048951048951, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1786524, Length=356, Percent_Identity=39.6067415730337, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI87081872, Length=331, Percent_Identity=36.2537764350453, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI1787583, Length=335, Percent_Identity=37.6119402985075, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1789828, Length=238, Percent_Identity=34.8739495798319, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI87081858, Length=265, Percent_Identity=30.9433962264151, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1786784, Length=235, Percent_Identity=26.3829787234043, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787375, Length=175, Percent_Identity=30.2857142857143, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082012, Length=211, Percent_Identity=27.0142180094787, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788713, Length=182, Percent_Identity=29.6703296703297, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788191, Length=122, Percent_Identity=39.344262295082, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789402, Length=125, Percent_Identity=36, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789809, Length=127, Percent_Identity=31.496062992126, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=34.7457627118644, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790552, Length=127, Percent_Identity=29.9212598425197, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI145693157, Length=122, Percent_Identity=32.7868852459016, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=120, Percent_Identity=34.1666666666667, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=130, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53985; Mature: 53854

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTRILVADDEESMRWVLSKALKRKGFTVDLADDGRQALALIQENSYDLAILDIKMPGM
CCEEEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCCCEEEEEEECCCC
SGLDLLDRIREMKSDLLVVIMTAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIVEKVGR
CCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHH
AREIAGQVSLLKQELKEHYQVEKNIIGNSAAMQSIYKTIGKVADSDITILIQGESGTGKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
MVARAIHFNSGRLGKPFVAINCAAIPRDLLESELFGSERGAFTGASERKQGKFEQANQGT
HHHHHHHCCCCCCCCCEEEEEEHHCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCE
IFLDEIGDMPLDLQAKILRVLQEHEVTRVGGTQSIAVNVRIVAATNQELQERVRQREFRE
EEEECCCCCCCCHHHHHHHHHHHCCHHHCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHH
DLYYRLNVVPITLAPLRERRDDIPELVRYFLDRTCTELSIPPKQLTPEAMALLSRHSWPG
HHHEEEEEEEEEHHHHHHHHCCHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHCCCCC
NVRELENTIKRAVILSNDPMLTEADFDGLQPEGEETAMTPQDASLEAIVEAKLRSCLTGI
CHHHHHHHHHHEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EKLDKSDIHAKVLQQVERPLIRFILEKTRWNQVKAADILGINRNTLRKKIHDLEIELKRG
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCHHHHHHHHHCCEEEEECC
>Mature Secondary Structure 
TLTRILVADDEESMRWVLSKALKRKGFTVDLADDGRQALALIQENSYDLAILDIKMPGM
CEEEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCCCEEEEEEECCCC
SGLDLLDRIREMKSDLLVVIMTAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIVEKVGR
CCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHH
AREIAGQVSLLKQELKEHYQVEKNIIGNSAAMQSIYKTIGKVADSDITILIQGESGTGKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
MVARAIHFNSGRLGKPFVAINCAAIPRDLLESELFGSERGAFTGASERKQGKFEQANQGT
HHHHHHHCCCCCCCCCEEEEEEHHCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCE
IFLDEIGDMPLDLQAKILRVLQEHEVTRVGGTQSIAVNVRIVAATNQELQERVRQREFRE
EEEECCCCCCCCHHHHHHHHHHHCCHHHCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHH
DLYYRLNVVPITLAPLRERRDDIPELVRYFLDRTCTELSIPPKQLTPEAMALLSRHSWPG
HHHEEEEEEEEEHHHHHHHHCCHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHCCCCC
NVRELENTIKRAVILSNDPMLTEADFDGLQPEGEETAMTPQDASLEAIVEAKLRSCLTGI
CHHHHHHHHHHEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EKLDKSDIHAKVLQQVERPLIRFILEKTRWNQVKAADILGINRNTLRKKIHDLEIELKRG
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCHHHHHHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7553451 [H]