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The map label for this gene is murA [H]

Identifier: 118581449

GI number: 118581449

Start: 3325511

End: 3326764

Strand: Reverse

Name: murA [H]

Synonym: Ppro_3044

Alternate gene names: 118581449

Gene position: 3326764-3325511 (Counterclockwise)

Preceding gene: 118581452

Following gene: 118581448

Centisome position: 83.0

GC content: 60.29

Gene sequence:

>1254_bases
ATGGACAAACTCATCATACAGGGTGGCACGAAGCTTAGCGGCGAGGTTCTGGTCAGTGGTTCGAAGAACGCAGCCTTGCC
GATACTGATCTCAACCGTTCTTGCGCCGGGGAAAAACGAAATCAGCAACGTCCCCTTCCTGCGAGACATCAATACAACCA
TCAAGGTGCTGGAATCCCTCGGCGCACGGGTCGAGGGGAATGGGCATGTGGTCAAGGTGGATACCGCAGGTATCAACAGC
CATGAAGCCACCTATGATCTGGTCAAGACCATGCGTGCCTCGGTGCTGGTGCTGGGGCCACTGCTGGCCCGCTTCGGCAA
GGCGCGTGTGTCTCTTCCCGGGGGCTGTGCCATCGGTGCCCGTCCGATCAATCTCCATCTCAAGGGACTACAGGCCTTGG
GGGCGGAGATCATTCTGGAACATGGCTATGTGGCGGCCAAGGCCAGACAGCTCAAGGGATCCCGCATCAACTTCGATGTC
TCCACCGTGGGGGGGACTGAGCATCTGATGATGGCAGCGGCCACCGCCAAGGGGGAGAGTCTCCTGGAAAACGCCGCCCG
TGAACCGGAGATCATCGACCTTGCTCGCATACTCAACCGCATGGGCGCCAGGATCGAGGGAGCGGGAACCGACACCATCA
GGATCCAGGGTGTCGCGGAGCTTGCGCCGGTCAGCTACGAAGTCATGCCGGACAGGATCGAGGCCGGCACCTTCATGATC
GCCGCGGCAATCACCGGCGGAGACATCAGGATCAAGGGCATGAAACTGGAGCATCTGGATGCGCTGGTATTCAAGCTTCA
GGACGCCGGCGTGGAGATCAGCAGCCGCGACAACGTGGTAAGGGTCAAGGGGCCAAGGAAAATCCGCAGCGTCAACATCA
AGACCCGCCCCTACCCCGGTTTCCCCACCGACATGCAGGCGCAGTTCATGGCGCTGATGTGCAAGGCGGATGGAGCCAGC
GTCATCTCGGAGAATATCTTCGAGAATCGTTTCATGCATGTGGCCGAGCTGTTACGCTTCGGGGCCGACATCGTCATCGA
GGGGAATGTCGCCACGGTCAAGGGGGTCAAAAAGCTCTCCGGGGCGCCGGTCATGGCCACCGACCTGCGCGCCTCCGCCT
CCCTCATCCTGGCTGGCCTGACATCGGACAATACCACCGAGGTCTCCCGGATCTACCACCTGGACCGTGGCTACGAGTCC
ATCGAGAAGAAACTGGCCGGCCTGGGCGCAAACATCGTGAGAGTCCAAGAATGA

Upstream 100 bases:

>100_bases
CATTTATTGAGTCCGGTGGCCTGGCGGAGCACATTTCCCTTTTCATCGGCCCGGCCATGGGCTACTATATTTTCTTTTTT
TAAACAGAAAGCGAAACAGC

Downstream 100 bases:

>100_bases
ACGATTTCATCACCATCGCCATTCCCAAGGGACGCATCCTTGAAGAATCCGTTGACCTGTTCGGCAGGATCGGCATCGAC
TGCCGGGAACTGCTGGGCGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MDKLIIQGGTKLSGEVLVSGSKNAALPILISTVLAPGKNEISNVPFLRDINTTIKVLESLGARVEGNGHVVKVDTAGINS
HEATYDLVKTMRASVLVLGPLLARFGKARVSLPGGCAIGARPINLHLKGLQALGAEIILEHGYVAAKARQLKGSRINFDV
STVGGTEHLMMAAATAKGESLLENAAREPEIIDLARILNRMGARIEGAGTDTIRIQGVAELAPVSYEVMPDRIEAGTFMI
AAAITGGDIRIKGMKLEHLDALVFKLQDAGVEISSRDNVVRVKGPRKIRSVNIKTRPYPGFPTDMQAQFMALMCKADGAS
VISENIFENRFMHVAELLRFGADIVIEGNVATVKGVKKLSGAPVMATDLRASASLILAGLTSDNTTEVSRIYHLDRGYES
IEKKLAGLGANIVRVQE

Sequences:

>Translated_417_residues
MDKLIIQGGTKLSGEVLVSGSKNAALPILISTVLAPGKNEISNVPFLRDINTTIKVLESLGARVEGNGHVVKVDTAGINS
HEATYDLVKTMRASVLVLGPLLARFGKARVSLPGGCAIGARPINLHLKGLQALGAEIILEHGYVAAKARQLKGSRINFDV
STVGGTEHLMMAAATAKGESLLENAAREPEIIDLARILNRMGARIEGAGTDTIRIQGVAELAPVSYEVMPDRIEAGTFMI
AAAITGGDIRIKGMKLEHLDALVFKLQDAGVEISSRDNVVRVKGPRKIRSVNIKTRPYPGFPTDMQAQFMALMCKADGAS
VISENIFENRFMHVAELLRFGADIVIEGNVATVKGVKKLSGAPVMATDLRASASLILAGLTSDNTTEVSRIYHLDRGYES
IEKKLAGLGANIVRVQE
>Mature_417_residues
MDKLIIQGGTKLSGEVLVSGSKNAALPILISTVLAPGKNEISNVPFLRDINTTIKVLESLGARVEGNGHVVKVDTAGINS
HEATYDLVKTMRASVLVLGPLLARFGKARVSLPGGCAIGARPINLHLKGLQALGAEIILEHGYVAAKARQLKGSRINFDV
STVGGTEHLMMAAATAKGESLLENAAREPEIIDLARILNRMGARIEGAGTDTIRIQGVAELAPVSYEVMPDRIEAGTFMI
AAAITGGDIRIKGMKLEHLDALVFKLQDAGVEISSRDNVVRVKGPRKIRSVNIKTRPYPGFPTDMQAQFMALMCKADGAS
VISENIFENRFMHVAELLRFGADIVIEGNVATVKGVKKLSGAPVMATDLRASASLILAGLTSDNTTEVSRIYHLDRGYES
IEKKLAGLGANIVRVQE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=55.0239234449761, Blast_Score=440, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44444; Mature: 44444

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00936 RIBOSOMAL_L35

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLIIQGGTKLSGEVLVSGSKNAALPILISTVLAPGKNEISNVPFLRDINTTIKVLESL
CCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHCCCCEEEHHHHHHHHHHHH
GARVEGNGHVVKVDTAGINSHEATYDLVKTMRASVLVLGPLLARFGKARVSLPGGCAIGA
CCEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEECC
RPINLHLKGLQALGAEIILEHGYVAAKARQLKGSRINFDVSTVGGTEHLMMAAATAKGES
EEEEEEEHHHHHCCHHHHHHCCCHHHHHHHCCCCEEEEEEEECCCCHHHEEEEHHCCCHH
LLENAAREPEIIDLARILNRMGARIEGAGTDTIRIQGVAELAPVSYEVMPDRIEAGTFMI
HHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEEEHHHCCCEEEECCCCCCCCEEEE
AAAITGGDIRIKGMKLEHLDALVFKLQDAGVEISSRDNVVRVKGPRKIRSVNIKTRPYPG
EEEEECCEEEEEEEEHHHHHHHHHHHHHCCEEEECCCCEEEEECCCEEEEEEEEECCCCC
FPTDMQAQFMALMCKADGASVISENIFENRFMHVAELLRFGADIVIEGNVATVKGVKKLS
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEHHHHHHC
GAPVMATDLRASASLILAGLTSDNTTEVSRIYHLDRGYESIEKKLAGLGANIVRVQE
CCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MDKLIIQGGTKLSGEVLVSGSKNAALPILISTVLAPGKNEISNVPFLRDINTTIKVLESL
CCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHCCCCEEEHHHHHHHHHHHH
GARVEGNGHVVKVDTAGINSHEATYDLVKTMRASVLVLGPLLARFGKARVSLPGGCAIGA
CCEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEECC
RPINLHLKGLQALGAEIILEHGYVAAKARQLKGSRINFDVSTVGGTEHLMMAAATAKGES
EEEEEEEHHHHHCCHHHHHHCCCHHHHHHHCCCCEEEEEEEECCCCHHHEEEEHHCCCHH
LLENAAREPEIIDLARILNRMGARIEGAGTDTIRIQGVAELAPVSYEVMPDRIEAGTFMI
HHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEEEHHHCCCEEEECCCCCCCCEEEE
AAAITGGDIRIKGMKLEHLDALVFKLQDAGVEISSRDNVVRVKGPRKIRSVNIKTRPYPG
EEEEECCEEEEEEEEHHHHHHHHHHHHHCCEEEECCCCEEEEECCCEEEEEEEEECCCCC
FPTDMQAQFMALMCKADGASVISENIFENRFMHVAELLRFGADIVIEGNVATVKGVKKLS
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEHHHHHHC
GAPVMATDLRASASLILAGLTSDNTTEVSRIYHLDRGYESIEKKLAGLGANIVRVQE
CCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA