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The map label for this gene is aphA [H]

Identifier: 118581417

GI number: 118581417

Start: 3288420

End: 3290090

Strand: Reverse

Name: aphA [H]

Synonym: Ppro_3012

Alternate gene names: 118581417

Gene position: 3290090-3288420 (Counterclockwise)

Preceding gene: 118581442

Following gene: 118581416

Centisome position: 82.09

GC content: 62.6

Gene sequence:

>1671_bases
ATGGCGTATCTGACGCCTTCGATTGCGCCGGATACTGGTCTGTTCGTGCCCCATAAGACTCCTGGTGGGAAACATGCCGC
CGGCACTGTTCCGCGGGGTGATGTTTTGACTCGGCAAAGCAGTGGGGTAGAGTTGAAGGTGACATGCGTTCCCCCTGGTG
CGTGGCGAATCGCCGCTTCCCGTCCGGGACGGGGAGGGGGGCGTGCCGGGTCGCTACATTCTGGAGGTAGTCCCATGAAA
AGAGAAAACGGTTGTCCGGAGATTGTGATCGTCGATGGGGGGGCGGATTCACCCGGTTCGCTGGCTGAGTTGCTGGTGGA
GCATGGCTATGGGGTTGTGACCGTCGGCGACTGGCGCCAGGCGCTCATCACCGCCGGGGACGATGTGCCGGGGCATGTCG
TGATCAGTCGCGCCTGCCTGGAAAAGCTGGAGGATGAACTGACCGGTGAGCTGAAGCGGGAGAATCAGCAACTGCGCGAG
GAGAACGCCCGCGGCCGGGAAGTGGAGGCGGCGCTGCGCGAGGAGGACGAGCAGCTGTGCACCATCCTCCTCGGCTATCC
GATTCCCCAGTTCGTCATCGACGGCAATCACCGGGTTGTCTACTGGAACCGGGCCATGGAGGCCTACAGCGGGATCGCGT
CGTGCGACGTGGTGGGAACTGACAGGCAGTGGAGCGCCTTCTATCCCTCTGCGCGTCCCTGCCTGGCGGACCTCCTGGTT
GATGATGGCGAGGATGGTCTGGCTGCCTGGTACGGGGATAGGGTGACCCGCTCCGGGTTGCTGCCCGACTGCTACGAGTG
CACTGATTTCTTTCCCGATCAGTCCGGGGGGGGGAGGTGGCTGCACTTCATTACAATCAAGATGAAGGATGTCAACGGAG
TCACCATCGGCGCCATCGAGACGCTGAACGACATCACCGACCGCAAACTGGCCGAGCAGGAGCTGCACAAGGCCTACAAC
GAACTGGACGAGCGGGTGAAGGCCCGCACCCGTGACCTGGAGGCGGCAAACCGGGAGCTGGAATCATTCGCCTATTCGGT
TTCCCATGATTTGCGCCAGCCGCTGCGGGCAATCGACGGTTTCAGCCAGGCGCTGCTGGAGGAGTATAACGACAGGCTGG
ACGACGAGGGGAGGGAGTATCTTGGCCGGCTCCGCGCCGGCAGCCAGCGCATGGGCATTCTCATCGACAACATCCTCAGG
CTATCCCGGCTTTCGCGTGAGGAAATGCACTACCAGACCGTGGACTTAAGCGCTATTGCCGCCGAGATCGCGGAGGAACT
GAAGGGGGCTGACCCGGACCGCCAGGGCGACTTTGTCATCGCCCCCGGATTGACGGTCCATGGCGATCCGGCACTGCTCA
GGATCGCCCTGCAGAACCTGCTGGCCAATGCCTGGAAGTTCTCCTCCCAGAAGGACCGGGCGCGGGTAGAGTTCGGTACA
CGGGAGGTGGAAGGAGAACGGGCTTTCCACGTCAGCGACAACGGAGCTGGTTTCGATATGACGTACGGCGACAAGCTATT
CGGCGTCTTCCAGCGGCTGCACGGCGCCAAGGAATTTCCCGGCACCGGCATCGGCCTTGCCATTGTGCAGCGCGTCATTC
ACCGTCACGGCGGCCGGGTCTGGGCTGAGGCTGAGGTCGGCAAGGGGGCCAGCTTCTATTTCGTCCTCTGA

Upstream 100 bases:

>100_bases
ATCCTTTTCACATGAGACGAGCTCATACAACTATTAAAAAATGATGAATTATAGAGTTTTTTGGGACGAAAGCAAAGGAA
AAGGAGGGGAGCGCGAAAAA

Downstream 100 bases:

>100_bases
AGCTGATTTTGCGCCGGCATACTGCCTGCGTTCGTGCGGACGGCCCGTTTCTGTACTGCCAGGGTGTTCTGGAGCAGCAG
TCGATACACTCACCCAAGGG

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MAYLTPSIAPDTGLFVPHKTPGGKHAAGTVPRGDVLTRQSSGVELKVTCVPPGAWRIAASRPGRGGGRAGSLHSGGSPMK
RENGCPEIVIVDGGADSPGSLAELLVEHGYGVVTVGDWRQALITAGDDVPGHVVISRACLEKLEDELTGELKRENQQLRE
ENARGREVEAALREEDEQLCTILLGYPIPQFVIDGNHRVVYWNRAMEAYSGIASCDVVGTDRQWSAFYPSARPCLADLLV
DDGEDGLAAWYGDRVTRSGLLPDCYECTDFFPDQSGGGRWLHFITIKMKDVNGVTIGAIETLNDITDRKLAEQELHKAYN
ELDERVKARTRDLEAANRELESFAYSVSHDLRQPLRAIDGFSQALLEEYNDRLDDEGREYLGRLRAGSQRMGILIDNILR
LSRLSREEMHYQTVDLSAIAAEIAEELKGADPDRQGDFVIAPGLTVHGDPALLRIALQNLLANAWKFSSQKDRARVEFGT
REVEGERAFHVSDNGAGFDMTYGDKLFGVFQRLHGAKEFPGTGIGLAIVQRVIHRHGGRVWAEAEVGKGASFYFVL

Sequences:

>Translated_556_residues
MAYLTPSIAPDTGLFVPHKTPGGKHAAGTVPRGDVLTRQSSGVELKVTCVPPGAWRIAASRPGRGGGRAGSLHSGGSPMK
RENGCPEIVIVDGGADSPGSLAELLVEHGYGVVTVGDWRQALITAGDDVPGHVVISRACLEKLEDELTGELKRENQQLRE
ENARGREVEAALREEDEQLCTILLGYPIPQFVIDGNHRVVYWNRAMEAYSGIASCDVVGTDRQWSAFYPSARPCLADLLV
DDGEDGLAAWYGDRVTRSGLLPDCYECTDFFPDQSGGGRWLHFITIKMKDVNGVTIGAIETLNDITDRKLAEQELHKAYN
ELDERVKARTRDLEAANRELESFAYSVSHDLRQPLRAIDGFSQALLEEYNDRLDDEGREYLGRLRAGSQRMGILIDNILR
LSRLSREEMHYQTVDLSAIAAEIAEELKGADPDRQGDFVIAPGLTVHGDPALLRIALQNLLANAWKFSSQKDRARVEFGT
REVEGERAFHVSDNGAGFDMTYGDKLFGVFQRLHGAKEFPGTGIGLAIVQRVIHRHGGRVWAEAEVGKGASFYFVL
>Mature_555_residues
AYLTPSIAPDTGLFVPHKTPGGKHAAGTVPRGDVLTRQSSGVELKVTCVPPGAWRIAASRPGRGGGRAGSLHSGGSPMKR
ENGCPEIVIVDGGADSPGSLAELLVEHGYGVVTVGDWRQALITAGDDVPGHVVISRACLEKLEDELTGELKRENQQLREE
NARGREVEAALREEDEQLCTILLGYPIPQFVIDGNHRVVYWNRAMEAYSGIASCDVVGTDRQWSAFYPSARPCLADLLVD
DGEDGLAAWYGDRVTRSGLLPDCYECTDFFPDQSGGGRWLHFITIKMKDVNGVTIGAIETLNDITDRKLAEQELHKAYNE
LDERVKARTRDLEAANRELESFAYSVSHDLRQPLRAIDGFSQALLEEYNDRLDDEGREYLGRLRAGSQRMGILIDNILRL
SRLSREEMHYQTVDLSAIAAEIAEELKGADPDRQGDFVIAPGLTVHGDPALLRIALQNLLANAWKFSSQKDRARVEFGTR
EVEGERAFHVSDNGAGFDMTYGDKLFGVFQRLHGAKEFPGTGIGLAIVQRVIHRHGGRVWAEAEVGKGASFYFVL

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=31.9148936170213, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788549, Length=282, Percent_Identity=26.9503546099291, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=32.3275862068966, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790861, Length=252, Percent_Identity=29.3650793650794, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=24.2677824267782, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=270, Percent_Identity=28.1481481481481, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=28.3333333333333, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786912, Length=216, Percent_Identity=27.3148148148148, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61050; Mature: 60919

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYLTPSIAPDTGLFVPHKTPGGKHAAGTVPRGDVLTRQSSGVELKVTCVPPGAWRIAAS
CCEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCEEEECC
RPGRGGGRAGSLHSGGSPMKRENGCPEIVIVDGGADSPGSLAELLVEHGYGVVTVGDWRQ
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCHHH
ALITAGDDVPGHVVISRACLEKLEDELTGELKRENQQLREENARGREVEAALREEDEQLC
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHH
TILLGYPIPQFVIDGNHRVVYWNRAMEAYSGIASCDVVGTDRQWSAFYPSARPCLADLLV
HHHHCCCCCCEEECCCCEEEEECHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
DDGEDGLAAWYGDRVTRSGLLPDCYECTDFFPDQSGGGRWLHFITIKMKDVNGVTIGAIE
CCCCCCCCHHHCCHHHHCCCCCCHHHHHHCCCCCCCCCEEEEEEEEEEECCCCEEEEHHH
TLNDITDRKLAEQELHKAYNELDERVKARTRDLEAANRELESFAYSVSHDLRQPLRAIDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSQALLEEYNDRLDDEGREYLGRLRAGSQRMGILIDNILRLSRLSREEMHYQTVDLSAIA
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEIAEELKGADPDRQGDFVIAPGLTVHGDPALLRIALQNLLANAWKFSSQKDRARVEFGT
HHHHHHHCCCCCCCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEECC
REVEGERAFHVSDNGAGFDMTYGDKLFGVFQRLHGAKEFPGTGIGLAIVQRVIHRHGGRV
EECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCE
WAEAEVGKGASFYFVL
EEEECCCCCCEEEEEC
>Mature Secondary Structure 
AYLTPSIAPDTGLFVPHKTPGGKHAAGTVPRGDVLTRQSSGVELKVTCVPPGAWRIAAS
CEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCEEEECC
RPGRGGGRAGSLHSGGSPMKRENGCPEIVIVDGGADSPGSLAELLVEHGYGVVTVGDWRQ
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCHHH
ALITAGDDVPGHVVISRACLEKLEDELTGELKRENQQLREENARGREVEAALREEDEQLC
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHH
TILLGYPIPQFVIDGNHRVVYWNRAMEAYSGIASCDVVGTDRQWSAFYPSARPCLADLLV
HHHHCCCCCCEEECCCCEEEEECHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
DDGEDGLAAWYGDRVTRSGLLPDCYECTDFFPDQSGGGRWLHFITIKMKDVNGVTIGAIE
CCCCCCCCHHHCCHHHHCCCCCCHHHHHHCCCCCCCCCEEEEEEEEEEECCCCEEEEHHH
TLNDITDRKLAEQELHKAYNELDERVKARTRDLEAANRELESFAYSVSHDLRQPLRAIDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSQALLEEYNDRLDDEGREYLGRLRAGSQRMGILIDNILRLSRLSREEMHYQTVDLSAIA
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEIAEELKGADPDRQGDFVIAPGLTVHGDPALLRIALQNLLANAWKFSSQKDRARVEFGT
HHHHHHHCCCCCCCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEECC
REVEGERAFHVSDNGAGFDMTYGDKLFGVFQRLHGAKEFPGTGIGLAIVQRVIHRHGGRV
EECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCE
WAEAEVGKGASFYFVL
EEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]