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The map label for this gene is corA [H]

Identifier: 118581385

GI number: 118581385

Start: 3249557

End: 3250909

Strand: Reverse

Name: corA [H]

Synonym: Ppro_2980

Alternate gene names: 118581385

Gene position: 3250909-3249557 (Counterclockwise)

Preceding gene: 118581386

Following gene: 118581384

Centisome position: 81.11

GC content: 61.79

Gene sequence:

>1353_bases
ATGATACGTGACACCATTAAAGAGCTGCTGAAACGGCAGAGGCTTCTGGAAGAGGCGCTTCAGCGGCAGAGTCTGCCGCG
GCAGGAAGTGGTGGAGTCCGTCGTGCAGAAACAGCACCTGTCCGAGGTCCGTTCGCTGCTCGCAGGCTTGGCGCCCGCCG
AAATAGCGGAGATCATCGATGAACTGAATCCGGAGGACCTGTTTCTGGTCTGGGGAGAGATCGATGAGGGGCTCCTCGAT
GAGATACTGGACGAGGTGTCCGATGCCACCCGCGATACCCTGGCCAGCCGCAGTTCGTATCTCGGGGCGGCCTGCGTGGT
TAACGCCTTTGAGCTGAGCCAGGGGCGCCTGTGCCAGACCACCATCGAATCCGTCGACGACCTGGAGGGGATCAAGCCGA
TCTGGGTTGACCTGGTGGGCACCACAGCCGCCGACCGGCGCAAGATCGGGCAGTTCTTCGGCCTGGAGCTACCCGACCCG
GAGGATCTGTGTGACATCGAGTCCAGCGCGCGCTTCTACGTTGAAGAGGGGGGCGAGATACACCTGCACTCCGATTTCCT
GCTGGATCGGGAGGGGGATTCGCGCAACGTGCCGGTGGCCTTCATTCTCTTCCGGGACATCCTCTTCTCGGTGCGCGAGG
AAGAGTTGCCGGTCTTCCGCCTCCAGCGTCTGCGTGCGCGCATCCAGACCGGGTATGTCTCCGATGGTATGGACATGCTG
CTGGACCTGTACGCGGCCAACGCCGAGTATTCGGCCGACTCGCTGGAAGAGATCTACTCGGCCCTGGGCGAGGTCGGCAA
GAAGGTGCTCAGCGAAGCCATGACCGACGAGGAGGCGGCCAAGATTCTGGCGGAGATCGCCGAGGAGGAGGACCTGAACG
GCCGCATCCGCCGCAACATCCTGGATACCCGGCGCGCGCTGACCTTTCTGATCCGCAGAAAACTCCTCTCTACCCCCCAG
TTCGAAGACGCCCGGCAGATCATGCGCGACATTGAGTCGCTGGACGGCCACACCGCCTTCCTGTTCGACAAGATCAACTT
TCTGATGGATGCCACCGTCGGTTTCATCAACATCAACCAGAACCGGGTCATCTACCGCCTGACCGTGCTCACCGTTATCT
TCATGCCGCTCAACCTGGTGGCCGGCATCGGCGGCATGTCCGAGTTCTCGGTGGTGACCCAAGCCATTCCCTGGCCCATT
TCCTATGGCCTCTTCACCATCGGGTTGATCGTCATGGCCTGGCTGACGCTGGTCATCCTGCGCTTCTACGAGCGGCGTCC
CGGTCCCGCCAAATCAACGGGCGAAAAGCGCTCCCGTTGGCTGCCGTCCCTGCGTAGTTCTCCACCCTCCTGA

Upstream 100 bases:

>100_bases
GACATATCGGCGATACTGTGACAAAAGGGAACGAAACTATTTCCATCGACCGGAAAGCATGAAACGTTCCGCTGAACTGT
TCGCGAGGTATGCGCCCCAC

Downstream 100 bases:

>100_bases
CGGCTTGTGATGCCGGCAAAAGCGATCTTTTCCTCCACTGTCCCGCAGAATTGAGTATTTTACCCGCTGACACGAGGGAT
ACGCCGTGACCAGCCACATA

Product: Mg2+ transporter protein, CorA family protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MIRDTIKELLKRQRLLEEALQRQSLPRQEVVESVVQKQHLSEVRSLLAGLAPAEIAEIIDELNPEDLFLVWGEIDEGLLD
EILDEVSDATRDTLASRSSYLGAACVVNAFELSQGRLCQTTIESVDDLEGIKPIWVDLVGTTAADRRKIGQFFGLELPDP
EDLCDIESSARFYVEEGGEIHLHSDFLLDREGDSRNVPVAFILFRDILFSVREEELPVFRLQRLRARIQTGYVSDGMDML
LDLYAANAEYSADSLEEIYSALGEVGKKVLSEAMTDEEAAKILAEIAEEEDLNGRIRRNILDTRRALTFLIRRKLLSTPQ
FEDARQIMRDIESLDGHTAFLFDKINFLMDATVGFININQNRVIYRLTVLTVIFMPLNLVAGIGGMSEFSVVTQAIPWPI
SYGLFTIGLIVMAWLTLVILRFYERRPGPAKSTGEKRSRWLPSLRSSPPS

Sequences:

>Translated_450_residues
MIRDTIKELLKRQRLLEEALQRQSLPRQEVVESVVQKQHLSEVRSLLAGLAPAEIAEIIDELNPEDLFLVWGEIDEGLLD
EILDEVSDATRDTLASRSSYLGAACVVNAFELSQGRLCQTTIESVDDLEGIKPIWVDLVGTTAADRRKIGQFFGLELPDP
EDLCDIESSARFYVEEGGEIHLHSDFLLDREGDSRNVPVAFILFRDILFSVREEELPVFRLQRLRARIQTGYVSDGMDML
LDLYAANAEYSADSLEEIYSALGEVGKKVLSEAMTDEEAAKILAEIAEEEDLNGRIRRNILDTRRALTFLIRRKLLSTPQ
FEDARQIMRDIESLDGHTAFLFDKINFLMDATVGFININQNRVIYRLTVLTVIFMPLNLVAGIGGMSEFSVVTQAIPWPI
SYGLFTIGLIVMAWLTLVILRFYERRPGPAKSTGEKRSRWLPSLRSSPPS
>Mature_450_residues
MIRDTIKELLKRQRLLEEALQRQSLPRQEVVESVVQKQHLSEVRSLLAGLAPAEIAEIIDELNPEDLFLVWGEIDEGLLD
EILDEVSDATRDTLASRSSYLGAACVVNAFELSQGRLCQTTIESVDDLEGIKPIWVDLVGTTAADRRKIGQFFGLELPDP
EDLCDIESSARFYVEEGGEIHLHSDFLLDREGDSRNVPVAFILFRDILFSVREEELPVFRLQRLRARIQTGYVSDGMDML
LDLYAANAEYSADSLEEIYSALGEVGKKVLSEAMTDEEAAKILAEIAEEEDLNGRIRRNILDTRRALTFLIRRKLLSTPQ
FEDARQIMRDIESLDGHTAFLFDKINFLMDATVGFININQNRVIYRLTVLTVIFMPLNLVAGIGGMSEFSVVTQAIPWPI
SYGLFTIGLIVMAWLTLVILRFYERRPGPAKSTGEKRSRWLPSLRSSPPS

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=298, Percent_Identity=39.9328859060403, Blast_Score=201, Evalue=8e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 50841; Mature: 50841

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRDTIKELLKRQRLLEEALQRQSLPRQEVVESVVQKQHLSEVRSLLAGLAPAEIAEIID
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ELNPEDLFLVWGEIDEGLLDEILDEVSDATRDTLASRSSYLGAACVVNAFELSQGRLCQT
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
TIESVDDLEGIKPIWVDLVGTTAADRRKIGQFFGLELPDPEDLCDIESSARFYVEEGGEI
HHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEECCCEE
HLHSDFLLDREGDSRNVPVAFILFRDILFSVREEELPVFRLQRLRARIQTGYVSDGMDML
EEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHH
LDLYAANAEYSADSLEEIYSALGEVGKKVLSEAMTDEEAAKILAEIAEEEDLNGRIRRNI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHH
LDTRRALTFLIRRKLLSTPQFEDARQIMRDIESLDGHTAFLFDKINFLMDATVGFININQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECC
NRVIYRLTVLTVIFMPLNLVAGIGGMSEFSVVTQAIPWPISYGLFTIGLIVMAWLTLVIL
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RFYERRPGPAKSTGEKRSRWLPSLRSSPPS
HHHHCCCCCCCCCCHHHHHHCCHHCCCCCC
>Mature Secondary Structure
MIRDTIKELLKRQRLLEEALQRQSLPRQEVVESVVQKQHLSEVRSLLAGLAPAEIAEIID
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ELNPEDLFLVWGEIDEGLLDEILDEVSDATRDTLASRSSYLGAACVVNAFELSQGRLCQT
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
TIESVDDLEGIKPIWVDLVGTTAADRRKIGQFFGLELPDPEDLCDIESSARFYVEEGGEI
HHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEECCCEE
HLHSDFLLDREGDSRNVPVAFILFRDILFSVREEELPVFRLQRLRARIQTGYVSDGMDML
EEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHH
LDLYAANAEYSADSLEEIYSALGEVGKKVLSEAMTDEEAAKILAEIAEEEDLNGRIRRNI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHH
LDTRRALTFLIRRKLLSTPQFEDARQIMRDIESLDGHTAFLFDKINFLMDATVGFININQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECC
NRVIYRLTVLTVIFMPLNLVAGIGGMSEFSVVTQAIPWPISYGLFTIGLIVMAWLTLVIL
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RFYERRPGPAKSTGEKRSRWLPSLRSSPPS
HHHHCCCCCCCCCCHHHHHHCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12219091 [H]