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The map label for this gene is kinB [H]

Identifier: 118581373

GI number: 118581373

Start: 3237826

End: 3239004

Strand: Reverse

Name: kinB [H]

Synonym: Ppro_2968

Alternate gene names: 118581373

Gene position: 3239004-3237826 (Counterclockwise)

Preceding gene: 118581374

Following gene: 118581372

Centisome position: 80.81

GC content: 61.92

Gene sequence:

>1179_bases
ATGAGCCCACAGACTCCCCAGAGGGTTTTGATCGTTGATGACGAGATGCTGGTGGCCAAGATCCTCTCCCTGCACCTGGA
GGAGTCCGGCTATCTGACCGAATGGGCCAAGGATGGCGAGCAGTGCCTGGCGCTGCTGGCGGAAAAAACCTATGCCCTGG
TGCTGCTGGATATCTGGATGCCGCAGATGAGCGGTGTGCAGGTGCTGGAACAGATCAGGGAGAGCGGAAACGATGTTGCC
GTGATCATGATGAGCGGCCATGGCAGCGAGAGCATGGCGGTGAACTGCATGAAAAACGGCGCCATGGATTACTTTGCCAA
GCCCTTCGAGTTCAACGATGTGCTCCAGCGGGTGGACCAGGCCATCGCCAACCGCGCCATGCGCCTGGAAAAGCAGCGCC
TGGAACGGGAAAAGGACGACTTCGTCTCCATGCTCTCCCATGACATGAAGAACCCGATCACCGCCGTGATCGGCTCCATC
GACATCATGCGCGAGGGGTGCCTGGGGCCGGTCGACCAGGAGCAGTCCGAGTATCTCCAGTCCGCCATCGACAGCTGCAA
TGAAGTGGTTGCCATGATTGACAACCTGCTGGATATCCATCGCTTCGAGGCTGGCCGCATGCGCCTGGACCTGCAGCCCA
GCGATCCCCGGGAACTGCTTTCGGCCATTGTTGGCAGGTTCGGCATGCTGGCCGGCCGCGAAGGAGTCGTGCTGAACGTC
GACGTGGACCCGGATCTTCCCTGGCTGGCCGTCGACCGTAGTGCCTTTTCCCGGACCGTCACCAACCTTCTCTCCAACGC
CCTCAAGTTCACGCTGGAAGGGGGGATGATCACCCTCTCCTGCCATTCCCTGGATACGAAGCGGGCGATGGAACTGCCGG
TCCCCGCCTATGCCGCGCAACAGGCCTCCCTGTTGTTCAATGGCCACGGGCACCTGGTGCGACTGAGCGTCAGGGATACG
GGCAGCGGCATCCCGCCGGAGGATCAGGAGAGGATCTTCGAGCGTTTCGTCCAGTCGAGCCAGGGGGGGAAGGGGCGCAG
CGGCGCCGGGCTCGGGCTGGCCTACTGCACGTTGACGGTGAAGGGTTTTGGCGGCGTGATCTGGGTCGAGAGCACACCGG
AACAGGGGAGCGAGTTCATCATCCTGCTCCCCGCCCTGGAAGAGTGCGATGGTGCATGA

Upstream 100 bases:

>100_bases
TGCGGATCGTGCCGGGCGATTACCGCAACATAAAGATCACCACTCCCGAAGACCTTATTCTGGCGGAAGCCTTTCTGGCC
GCTTTTCGGCAGGTGCTCCC

Downstream 100 bases:

>100_bases
TGCCGGACAACCGCAGGGAGGGTGCCGGCCATGATCCGGGCATTGGTTGCGCTGCTGCTGGTGGCCGGGCTCTGCCTGGC
CGCGCCGCTTCAGGCTGCGG

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSPQTPQRVLIVDDEMLVAKILSLHLEESGYLTEWAKDGEQCLALLAEKTYALVLLDIWMPQMSGVQVLEQIRESGNDVA
VIMMSGHGSESMAVNCMKNGAMDYFAKPFEFNDVLQRVDQAIANRAMRLEKQRLEREKDDFVSMLSHDMKNPITAVIGSI
DIMREGCLGPVDQEQSEYLQSAIDSCNEVVAMIDNLLDIHRFEAGRMRLDLQPSDPRELLSAIVGRFGMLAGREGVVLNV
DVDPDLPWLAVDRSAFSRTVTNLLSNALKFTLEGGMITLSCHSLDTKRAMELPVPAYAAQQASLLFNGHGHLVRLSVRDT
GSGIPPEDQERIFERFVQSSQGGKGRSGAGLGLAYCTLTVKGFGGVIWVESTPEQGSEFIILLPALEECDGA

Sequences:

>Translated_392_residues
MSPQTPQRVLIVDDEMLVAKILSLHLEESGYLTEWAKDGEQCLALLAEKTYALVLLDIWMPQMSGVQVLEQIRESGNDVA
VIMMSGHGSESMAVNCMKNGAMDYFAKPFEFNDVLQRVDQAIANRAMRLEKQRLEREKDDFVSMLSHDMKNPITAVIGSI
DIMREGCLGPVDQEQSEYLQSAIDSCNEVVAMIDNLLDIHRFEAGRMRLDLQPSDPRELLSAIVGRFGMLAGREGVVLNV
DVDPDLPWLAVDRSAFSRTVTNLLSNALKFTLEGGMITLSCHSLDTKRAMELPVPAYAAQQASLLFNGHGHLVRLSVRDT
GSGIPPEDQERIFERFVQSSQGGKGRSGAGLGLAYCTLTVKGFGGVIWVESTPEQGSEFIILLPALEECDGA
>Mature_391_residues
SPQTPQRVLIVDDEMLVAKILSLHLEESGYLTEWAKDGEQCLALLAEKTYALVLLDIWMPQMSGVQVLEQIRESGNDVAV
IMMSGHGSESMAVNCMKNGAMDYFAKPFEFNDVLQRVDQAIANRAMRLEKQRLEREKDDFVSMLSHDMKNPITAVIGSID
IMREGCLGPVDQEQSEYLQSAIDSCNEVVAMIDNLLDIHRFEAGRMRLDLQPSDPRELLSAIVGRFGMLAGREGVVLNVD
VDPDLPWLAVDRSAFSRTVTNLLSNALKFTLEGGMITLSCHSLDTKRAMELPVPAYAAQQASLLFNGHGHLVRLSVRDTG
SGIPPEDQERIFERFVQSSQGGKGRSGAGLGLAYCTLTVKGFGGVIWVESTPEQGSEFIILLPALEECDGA

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB, probably in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=265, Percent_Identity=27.5471698113208, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1789149, Length=263, Percent_Identity=30.0380228136882, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI145693157, Length=275, Percent_Identity=26.9090909090909, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI87081816, Length=349, Percent_Identity=28.9398280802292, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994928, Length=269, Percent_Identity=27.5092936802974, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786912, Length=282, Percent_Identity=27.3049645390071, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788550, Length=129, Percent_Identity=34.1085271317829, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790861, Length=276, Percent_Identity=28.2608695652174, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87082128, Length=282, Percent_Identity=26.5957446808511, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=32.7586206896552, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788393, Length=274, Percent_Identity=24.8175182481752, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786783, Length=279, Percent_Identity=24.3727598566308, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=27.3092369477912, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=33.6206896551724, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082012, Length=111, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789809, Length=126, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786600, Length=254, Percent_Identity=24.0157480314961, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790300, Length=269, Percent_Identity=27.1375464684015, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786599, Length=121, Percent_Identity=32.2314049586777, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786784, Length=111, Percent_Identity=29.7297297297297, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789402, Length=112, Percent_Identity=29.4642857142857, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790863, Length=126, Percent_Identity=32.5396825396825, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013656
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF08448 PAS_4 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43137; Mature: 43006

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPQTPQRVLIVDDEMLVAKILSLHLEESGYLTEWAKDGEQCLALLAEKTYALVLLDIWM
CCCCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHEEEEEHHC
PQMSGVQVLEQIRESGNDVAVIMMSGHGSESMAVNCMKNGAMDYFAKPFEFNDVLQRVDQ
CCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHEEHHHHCCCHHHHCCCCCHHHHHHHHHH
AIANRAMRLEKQRLEREKDDFVSMLSHDMKNPITAVIGSIDIMREGCLGPVDQEQSEYLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
SAIDSCNEVVAMIDNLLDIHRFEAGRMRLDLQPSDPRELLSAIVGRFGMLAGREGVVLNV
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
DVDPDLPWLAVDRSAFSRTVTNLLSNALKFTLEGGMITLSCHSLDTKRAMELPVPAYAAQ
ECCCCCCEEEECHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHCCCCCHHHHC
QASLLFNGHGHLVRLSVRDTGSGIPPEDQERIFERFVQSSQGGKGRSGAGLGLAYCTLTV
CCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEE
KGFGGVIWVESTPEQGSEFIILLPALEECDGA
ECCCCEEEEECCCCCCCCEEEEEECHHCCCCC
>Mature Secondary Structure 
SPQTPQRVLIVDDEMLVAKILSLHLEESGYLTEWAKDGEQCLALLAEKTYALVLLDIWM
CCCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHEEEEEHHC
PQMSGVQVLEQIRESGNDVAVIMMSGHGSESMAVNCMKNGAMDYFAKPFEFNDVLQRVDQ
CCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHEEHHHHCCCHHHHCCCCCHHHHHHHHHH
AIANRAMRLEKQRLEREKDDFVSMLSHDMKNPITAVIGSIDIMREGCLGPVDQEQSEYLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
SAIDSCNEVVAMIDNLLDIHRFEAGRMRLDLQPSDPRELLSAIVGRFGMLAGREGVVLNV
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
DVDPDLPWLAVDRSAFSRTVTNLLSNALKFTLEGGMITLSCHSLDTKRAMELPVPAYAAQ
ECCCCCCEEEECHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHCCCCCHHHHC
QASLLFNGHGHLVRLSVRDTGSGIPPEDQERIFERFVQSSQGGKGRSGAGLGLAYCTLTV
CCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEE
KGFGGVIWVESTPEQGSEFIILLPALEECDGA
ECCCCEEEEECCCCCCCCEEEEEECHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9218420 [H]