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The map label for this gene is cusB [H]

Identifier: 118581333

GI number: 118581333

Start: 3202278

End: 3203645

Strand: Reverse

Name: cusB [H]

Synonym: Ppro_2928

Alternate gene names: 118581333

Gene position: 3203645-3202278 (Counterclockwise)

Preceding gene: 118581334

Following gene: 118581332

Centisome position: 79.93

GC content: 62.57

Gene sequence:

>1368_bases
ATGATTCGGAACAAAAAGATTCTGTACCCCCTGATACTGCTGGTTCTGCTTGCATCCGTTGGCGGCGGCTGGCTCCTGTG
GCGGGAGAGGGAGCACGACCATGCGGGGGAACGCAAGGCGGCCCAAGGGAAATTGCTCTACACCTGTCCCATGCACCCCT
TCATCATCAAGGACAGGCCGGGAGCCTGCCCGATCTGCGGCATGGAACTGGTCAGGAAGCTGGAAAGCGCGGCTGCTGCC
CAGTCTGGCGGACATAACGGGCAGGCAGACATGCCCGGCCATGTGTCGCTCTCGGAAAGCCAGCGGGTGATGGCCAATGT
GGCCACGGTGGAGGCCTGGCAGCAATCACTCAACAAAGAGATCACCGCCAGCGGCATCGTCCAGTTCGACCAGTCGCGTC
AGGCCAAGGTCACCTCCTGGATCGCCGGTCGCATTGACCGGCTCAACGTCAACAGCGTTGCTGCGTCCGTCTCCCGCAAC
AGGCCGGTGGCCGAGCTGTACTCGCCCGAGCTGGTGGCCACCCAGCTGGAGTACCTGCTGGCGCTCAAGAGCCGTGATCA
GCTGAAAGACTCCCCCATCCCCTCCATCTCCCAGAACGGCGAGGGGCTGGTGGCATCGGCCAGGCAGCGCCTGCTGCTGT
TCGGGGTCAGGGAGAGCCAGATCGCTGCACTGGAAAAGGCCGGCAAGCCCAACATCAGGCTCCCGATCTATACGCCACTC
TCCGGCGTCGTCATCGAAAAGATGGTTCAGCAGGGACAGTACGTCAATGTGGGTGATGTGCTCTTCACTATCGCCGATCT
CTCCACTGTCTGGATAGAGTTGGACATCTACGAGCCCGACCTGGCCATTGTCCGTGTCGGGCAGCGGGTGGAGATCCATT
CTCCCTCCTTTTCGGGAGGGACGCTTTCCGGAAGGATCGCCCTGGTGAACCCCTTTCTGGATCCCAGGAGCCGCACGGTC
AAGGCCCGGGTAGAGATGGCCAACCCCGGCATGAGACTGAAACCGGACATGTTCGTAAGCGCACTGATCAGGGTGCCGCT
TGGTACGGCACTGGTCGTGCCGGTCAGCGCGGTCATTGACAGCGGCAAGCGACGTCTGGTCTGGGTAGAGAGCTCGCCCG
GCATGTTTGAGCCGCGCCAGGTCCAGGTGGGACAGCAGGCCGGTGACCGGGTCCAGATCCTGTCGGGGCTTAGGGAGGGG
GAGAAGGTGGCCGTCTCCGGCGGCTACCTGATCGACTCGGAAGCGCAGCTCAAGTCGGGGACCAGGGACCAGGGAGCGGG
AACGGGAGGGCATCAGGGACATGGTACGCCAGCGCCCAGGGCGCCGGTGAAAAAGGACCCGCTGAGCATGGATGATATGA
AAATGTGA

Upstream 100 bases:

>100_bases
GCGCAGGGCTCTTGTTACCATTTTCGCCCCCTGGCCTGCGTTGGCTGGATCCGGGATGAGTCTCGCGGAAACGGCACAAA
CCACCATGAGGTGTTCGATC

Downstream 100 bases:

>100_bases
CGGTGAAAGACCATGGAACACGGAAAAGGCGGAAAGCACGGAAAGAACGGAAAGAACGGAAAGAACGGAAAAGGCACGAA
CACGATGCTGCATGCGACGG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MIRNKKILYPLILLVLLASVGGGWLLWREREHDHAGERKAAQGKLLYTCPMHPFIIKDRPGACPICGMELVRKLESAAAA
QSGGHNGQADMPGHVSLSESQRVMANVATVEAWQQSLNKEITASGIVQFDQSRQAKVTSWIAGRIDRLNVNSVAASVSRN
RPVAELYSPELVATQLEYLLALKSRDQLKDSPIPSISQNGEGLVASARQRLLLFGVRESQIAALEKAGKPNIRLPIYTPL
SGVVIEKMVQQGQYVNVGDVLFTIADLSTVWIELDIYEPDLAIVRVGQRVEIHSPSFSGGTLSGRIALVNPFLDPRSRTV
KARVEMANPGMRLKPDMFVSALIRVPLGTALVVPVSAVIDSGKRRLVWVESSPGMFEPRQVQVGQQAGDRVQILSGLREG
EKVAVSGGYLIDSEAQLKSGTRDQGAGTGGHQGHGTPAPRAPVKKDPLSMDDMKM

Sequences:

>Translated_455_residues
MIRNKKILYPLILLVLLASVGGGWLLWREREHDHAGERKAAQGKLLYTCPMHPFIIKDRPGACPICGMELVRKLESAAAA
QSGGHNGQADMPGHVSLSESQRVMANVATVEAWQQSLNKEITASGIVQFDQSRQAKVTSWIAGRIDRLNVNSVAASVSRN
RPVAELYSPELVATQLEYLLALKSRDQLKDSPIPSISQNGEGLVASARQRLLLFGVRESQIAALEKAGKPNIRLPIYTPL
SGVVIEKMVQQGQYVNVGDVLFTIADLSTVWIELDIYEPDLAIVRVGQRVEIHSPSFSGGTLSGRIALVNPFLDPRSRTV
KARVEMANPGMRLKPDMFVSALIRVPLGTALVVPVSAVIDSGKRRLVWVESSPGMFEPRQVQVGQQAGDRVQILSGLREG
EKVAVSGGYLIDSEAQLKSGTRDQGAGTGGHQGHGTPAPRAPVKKDPLSMDDMKM
>Mature_455_residues
MIRNKKILYPLILLVLLASVGGGWLLWREREHDHAGERKAAQGKLLYTCPMHPFIIKDRPGACPICGMELVRKLESAAAA
QSGGHNGQADMPGHVSLSESQRVMANVATVEAWQQSLNKEITASGIVQFDQSRQAKVTSWIAGRIDRLNVNSVAASVSRN
RPVAELYSPELVATQLEYLLALKSRDQLKDSPIPSISQNGEGLVASARQRLLLFGVRESQIAALEKAGKPNIRLPIYTPL
SGVVIEKMVQQGQYVNVGDVLFTIADLSTVWIELDIYEPDLAIVRVGQRVEIHSPSFSGGTLSGRIALVNPFLDPRSRTV
KARVEMANPGMRLKPDMFVSALIRVPLGTALVVPVSAVIDSGKRRLVWVESSPGMFEPRQVQVGQQAGDRVQILSGLREG
EKVAVSGGYLIDSEAQLKSGTRDQGAGTGGHQGHGTPAPRAPVKKDPLSMDDMKM

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=429, Percent_Identity=26.8065268065268, Blast_Score=128, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49374; Mature: 49374

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRNKKILYPLILLVLLASVGGGWLLWREREHDHAGERKAAQGKLLYTCPMHPFIIKDRP
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHCCCEEEECCCCCEEEECCC
GACPICGMELVRKLESAAAAQSGGHNGQADMPGHVSLSESQRVMANVATVEAWQQSLNKE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCC
ITASGIVQFDQSRQAKVTSWIAGRIDRLNVNSVAASVSRNRPVAELYSPELVATQLEYLL
CCHHHHEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHH
ALKSRDQLKDSPIPSISQNGEGLVASARQRLLLFGVRESQIAALEKAGKPNIRLPIYTPL
HHHCHHHHCCCCCCCCCCCCCCHHHHHHCEEEEEECCHHHHHHHHHCCCCCEEEEEECCC
SGVVIEKMVQQGQYVNVGDVLFTIADLSTVWIELDIYEPDLAIVRVGQRVEIHSPSFSGG
HHHHHHHHHHCCCEEEHHHHHHHHHCCEEEEEEEEEECCCEEEEEECCEEEEECCCCCCC
TLSGRIALVNPFLDPRSRTVKARVEMANPGMRLKPDMFVSALIRVPLGTALVVPVSAVID
CCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHC
SGKRRLVWVESSPGMFEPRQVQVGQQAGDRVQILSGLREGEKVAVSGGYLIDSEAQLKSG
CCCEEEEEEECCCCCCCCHHEECCHHCCCHHHHHHHCCCCCEEEEECCEEECCCHHHHCC
TRDQGAGTGGHQGHGTPAPRAPVKKDPLSMDDMKM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIRNKKILYPLILLVLLASVGGGWLLWREREHDHAGERKAAQGKLLYTCPMHPFIIKDRP
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHCCCEEEECCCCCEEEECCC
GACPICGMELVRKLESAAAAQSGGHNGQADMPGHVSLSESQRVMANVATVEAWQQSLNKE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCC
ITASGIVQFDQSRQAKVTSWIAGRIDRLNVNSVAASVSRNRPVAELYSPELVATQLEYLL
CCHHHHEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHH
ALKSRDQLKDSPIPSISQNGEGLVASARQRLLLFGVRESQIAALEKAGKPNIRLPIYTPL
HHHCHHHHCCCCCCCCCCCCCCHHHHHHCEEEEEECCHHHHHHHHHCCCCCEEEEEECCC
SGVVIEKMVQQGQYVNVGDVLFTIADLSTVWIELDIYEPDLAIVRVGQRVEIHSPSFSGG
HHHHHHHHHHCCCEEEHHHHHHHHHCCEEEEEEEEEECCCEEEEEECCEEEEECCCCCCC
TLSGRIALVNPFLDPRSRTVKARVEMANPGMRLKPDMFVSALIRVPLGTALVVPVSAVID
CCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHC
SGKRRLVWVESSPGMFEPRQVQVGQQAGDRVQILSGLREGEKVAVSGGYLIDSEAQLKSG
CCCEEEEEEECCCCCCCCHHEECCHHCCCHHHHHHHCCCCCEEEEECCEEECCCHHHHCC
TRDQGAGTGGHQGHGTPAPRAPVKKDPLSMDDMKM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]