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The map label for this gene is lpxH [H]

Identifier: 118581302

GI number: 118581302

Start: 3169801

End: 3170532

Strand: Reverse

Name: lpxH [H]

Synonym: Ppro_2897

Alternate gene names: 118581302

Gene position: 3170532-3169801 (Counterclockwise)

Preceding gene: 118581306

Following gene: 118581297

Centisome position: 79.11

GC content: 61.61

Gene sequence:

>732_bases
ATGCGTACGATCTTTCTCGCCGATGCCCACCTGAGGTCCCCCGACGATTTAAATTACCGGATGCTGCTCCGCTTTCTGCG
CGGTCTTGAGGGAATCACGGAAACCCTGTTCATCATGGGCGACCTGTTCGATTTCTGGATCGGTTTTCCCTCCCACCCCT
TCCGGCAGTACGATCCGCTGCTGGATGCGCTGCTGGCGCTGAAACGGAGCGGCTGTCGTCTGGTTTACTTCGAGGGTAAT
CACGATTTCCACCTGGGCAGCATCTTTTACGAGCGTCTGGCAGCCGAAGTTCATACCAGGCCTGCCATCCGCACGGTTCA
GGGGAGGCGGCTCTTTCTCTGCCATGGCGACCAGATCAACCGGGCCGACCACGGTTACCGCCTGCTGCGCCTTGTGCTGC
GCAACCGTCTGGCCGCCGCGACGGTCAGGCACGTTCCCCCCGCGTTGGCGCTGTGTATCAGGGAGCGCCTCCAGCATGCC
AGCCGCTCCAGCTATGGGAGCAAGTCGGTGCGTTGGGATTACGGCCGGATCATCCGTGACTTTGCCCGTTCGGTGCACCG
CATGGGGTGCACCGGGCTGGTCACCGGCCATTTTCATCTGGCCTTCTGCGAGGAACTGGATTGCGGTTCCTTCACGATCC
TCTCCCTGGGGGAGTGGATGGAGCGCCTGACCTATGGCGAGATGGTGGCAGGCAGGCTACGTCTCAGCGAGTACCTGCCT
GATCGCCCGTAG

Upstream 100 bases:

>100_bases
TTCATCCCAGACAATTTCAACGTTGTGCACAAATGCCATAGTGTCAGACCTCTATTCCTTGTTGACTTCCGCGGGGAGTG
ACAGCACAATTCCCCCCACT

Downstream 100 bases:

>100_bases
GGGCAAACCCAGCGTGGGCGCTAGGGATTCCTCTCCCTGTCGAAAAACGCCATCAGGGCCTGTTGCCCCACCTGGGAGGA
TTTGATCTTCCAACGGTCCT

Product: metallophosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRTIFLADAHLRSPDDLNYRMLLRFLRGLEGITETLFIMGDLFDFWIGFPSHPFRQYDPLLDALLALKRSGCRLVYFEGN
HDFHLGSIFYERLAAEVHTRPAIRTVQGRRLFLCHGDQINRADHGYRLLRLVLRNRLAAATVRHVPPALALCIRERLQHA
SRSSYGSKSVRWDYGRIIRDFARSVHRMGCTGLVTGHFHLAFCEELDCGSFTILSLGEWMERLTYGEMVAGRLRLSEYLP
DRP

Sequences:

>Translated_243_residues
MRTIFLADAHLRSPDDLNYRMLLRFLRGLEGITETLFIMGDLFDFWIGFPSHPFRQYDPLLDALLALKRSGCRLVYFEGN
HDFHLGSIFYERLAAEVHTRPAIRTVQGRRLFLCHGDQINRADHGYRLLRLVLRNRLAAATVRHVPPALALCIRERLQHA
SRSSYGSKSVRWDYGRIIRDFARSVHRMGCTGLVTGHFHLAFCEELDCGSFTILSLGEWMERLTYGEMVAGRLRLSEYLP
DRP
>Mature_243_residues
MRTIFLADAHLRSPDDLNYRMLLRFLRGLEGITETLFIMGDLFDFWIGFPSHPFRQYDPLLDALLALKRSGCRLVYFEGN
HDFHLGSIFYERLAAEVHTRPAIRTVQGRRLFLCHGDQINRADHGYRLLRLVLRNRLAAATVRHVPPALALCIRERLQHA
SRSSYGSKSVRWDYGRIIRDFARSVHRMGCTGLVTGHFHLAFCEELDCGSFTILSLGEWMERLTYGEMVAGRLRLSEYLP
DRP

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=237, Percent_Identity=28.6919831223629, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 28152; Mature: 28152

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIFLADAHLRSPDDLNYRMLLRFLRGLEGITETLFIMGDLFDFWIGFPSHPFRQYDPL
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LDALLALKRSGCRLVYFEGNHDFHLGSIFYERLAAEVHTRPAIRTVQGRRLFLCHGDQIN
HHHHHHHHHCCCEEEEEECCCCEEHHHHHHHHHHHHHHCCCHHEECCCCEEEEEECCCCC
RADHGYRLLRLVLRNRLAAATVRHVPPALALCIRERLQHASRSSYGSKSVRWDYGRIIRD
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
FARSVHRMGCTGLVTGHFHLAFCEELDCGSFTILSLGEWMERLTYGEMVAGRLRLSEYLP
HHHHHHHCCCCEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DRP
CCC
>Mature Secondary Structure
MRTIFLADAHLRSPDDLNYRMLLRFLRGLEGITETLFIMGDLFDFWIGFPSHPFRQYDPL
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LDALLALKRSGCRLVYFEGNHDFHLGSIFYERLAAEVHTRPAIRTVQGRRLFLCHGDQIN
HHHHHHHHHCCCEEEEEECCCCEEHHHHHHHHHHHHHHCCCHHEECCCCEEEEEECCCCC
RADHGYRLLRLVLRNRLAAATVRHVPPALALCIRERLQHASRSSYGSKSVRWDYGRIIRD
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
FARSVHRMGCTGLVTGHFHLAFCEELDCGSFTILSLGEWMERLTYGEMVAGRLRLSEYLP
HHHHHHHCCCCEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DRP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA