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The map label for this gene is zraS [C]

Identifier: 118581119

GI number: 118581119

Start: 2949817

End: 2952255

Strand: Direct

Name: zraS [C]

Synonym: Ppro_2709

Alternate gene names: 118581119

Gene position: 2949817-2952255 (Clockwise)

Preceding gene: 118581118

Following gene: 118581125

Centisome position: 73.6

GC content: 58.02

Gene sequence:

>2439_bases
ATGAGTGAATACCGACTCTCCGAACTGCTTGACATGGGCATCATCCAGAAAATGGCCGACACCCACTATCGGGCAACGGG
CATCCCAATCGGCATCATCGACGCCATCGACGATGCTGTTCTGGTAGGCTCCGGCTGGCAGGAGATCTGCGTCAGATTCC
ACCGCGCAGCCCTGCTTTCACTGCAGCGTTGCCGGGAAAGCGACAACTACATCAAGAGCCATCTCGTGGAAGGCCAGTCC
TGCCACTACAGATGCAAAAACGGCCTTAATGACATAGGTATTCCGATTATTGTTGCGGGGCGACATCTGGCGACCATGTT
TCTGGGACAATTTTTCTATGAAGAAGAGGAACCGGAGCGTGAGTACTTCATCCAACAGGCCGATGAGTACGGTTTCGATC
GTGACGAGTATCTTGCCGCCCTTGACCACGTGCCACGCTTCAGCCATGAAAAAGTCAACAACATGCTGGAGTACGACAAG
GTGCTGACAGTCTTCATCGCCGACTTGGCGGAGCGTTCGCTCCAGAAAATGCAGGCCGAGGAGGAGACCCGGGCAAGTGA
GCGTAAATTTCACACCATCCTTGACCAGGCCTATCAGTTCATCGCTCTCCTCTCCACGGAAGGCAGAATTCAGGAGGCAA
ACAGGACCGTCCTGCAATTCGGCGGCATCGAGGATAACTGCGCAACGGGAAAGCTGTTTTGGGAAACCAGCTGGTGGAGC
CACTCCCCTGAACTGCGGAAAAAAATCCGTGACTCCGTGCATAAGGTTGTCCGGGGGGAGTTTATCAGGTTCGAGGCGAC
CCACCCTGCAACCGATGGGACCCTGCAGTATGTGGATCTGTCTCTCAAGCCGGTCAGGAATCCGACCGGCGCTGTGGTCC
TTCTGATTGCGGAAGCCAGGGATATCAGCGAACAAAAGCGGGTGGAACAGGCTCTCGAGCTGAGCAACCTTGTGGTGGAA
AACAGCCAGGTGGTGCTCTTCCGCTGGAAAGCAGTCGAGGGATGGCCGGTCGTCATGGTTTCCCGCAACGTGAGCCAGTT
CGGCTATACTCCGGAAGAATTCCTCTCCGGCACGCTCCACTATGCATCAATCATCCACCCTGAAGATCTTGATCGAGTAA
TCCGGGAAGTCCGGTATTTTTCAACCCGCGGCGTCTCCCACACCCACCATGAATACCGGATCATCGCCAAAGACGGCCGC
GTACACTGGGTTGTCGAACGTTCTTTGGTTGAGCGCAACAACAAGGGGGAGATCGATTTTTTCCAGGGAGTGGTGATAGA
CACCACCGAGCGCAGACACATGGAGGAGGAACTGGTCAAGGCCCAGAAACTGGAATCCGTCGGCCTGCTTGCCGGCGGCA
TCGCCCACGACTTCAACAACATCCTCACCGGCATCCTGGGCAACGCGTCTCTCGCGAAGATGCTGTTCTCCCCCCAGGAC
AGGGCATATGCCTATGTGAGCAACATCGAAAGCGCCGCCTACCGGGCCAAGGACCTGACTCTGCAGTTCCTGACCTTCTC
CAAGGGGGGCGCTCCCATCAAAAAACCGGTGAACAGCGTTGAACTGATACGCAACAACACGCAGCTGGCCCTAAGCGGCC
TCAAATCAACCTGCGAGCTGAGCGTTCCGGATGACCTGCGGATCGTCGAGGTCGATGAGGGACAGATCAGCCAGGTGATC
AACAACCTGATCATCAACGCGGACCAGGCCATGCCGCGGGGTGGCGTCATCCGGGTGGTCTGCGAAAACGTGGAGACAAG
CGCCAGCAACGGGCTTCCCCTGAAAGAGGGCAGCTATGTCAGGGTCAGCGTCAGCGACCAGGGGGCTGGAATAACGGCGG
AGCACAGGGGAAAGATCTTCGACCCCTATTTCACCACAAAAGATAGGGGGCACGGCCTGGGCCTCGCCTCGGCCTACGCC
ATCATGAAGAAGCACGCCGGCCACATCTGCGTGGATTCAAAACCGGGCGCCGGCGCGACCTTCACCATCTATCTCCCTGC
TTCCGACGCAGCGACGGCCATTACAACGGAAGAGCCCGCCACGGCCGCCGCCGGCAGCGGCAGGATACTGGTCATGGATG
ACGAGCCGCTTGTGAGAATGGTAACGGGAGAGATGCTGGAACATATGGGCTACGACGTGGAATTCGCCCAGAATGGCGAG
GAGGCCCTGGCCATGTACGGCGCGGCCCGCGAGTCAGGTGTCCCCTTTGATGCGGTGATCATGGACCTGACCGTCCCCGG
CGGCATGGGGGGCAGGGAGGCGATCCAGAGAATCCGGGAGATTAATCCGAACGTCAGGGCCATCGTTTCCAGCGGCTATT
CTGACGACCCGGTCATGGCCAATCACCTGAACTACGGCTTCGCGGGGGTGGTGGTGAAACCGTACGACCTGGGCGAGCTG
GGTGCCCAGTTGGAGAGGGTATTGCGGAAACAGGAGTGA

Upstream 100 bases:

>100_bases
TTTTTCACAAACCGCCATTCATGCTCCGCGTAGACAGTGTGTTCTAATGTGAGATATACTGGTCACGCTTACCCACACGC
TGCGCCTCCAGGAGTAAATG

Downstream 100 bases:

>100_bases
GGCGAGAAGCGAGGAGTCAGAAACCAGCAGCCAGAATTCGGAATTTCGTTCCTCTGACAGAAGAAGGGGCGGGGCAACAG
CCCCACCCCTTCTTCTGTCA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 812; Mature: 811

Protein sequence:

>812_residues
MSEYRLSELLDMGIIQKMADTHYRATGIPIGIIDAIDDAVLVGSGWQEICVRFHRAALLSLQRCRESDNYIKSHLVEGQS
CHYRCKNGLNDIGIPIIVAGRHLATMFLGQFFYEEEEPEREYFIQQADEYGFDRDEYLAALDHVPRFSHEKVNNMLEYDK
VLTVFIADLAERSLQKMQAEEETRASERKFHTILDQAYQFIALLSTEGRIQEANRTVLQFGGIEDNCATGKLFWETSWWS
HSPELRKKIRDSVHKVVRGEFIRFEATHPATDGTLQYVDLSLKPVRNPTGAVVLLIAEARDISEQKRVEQALELSNLVVE
NSQVVLFRWKAVEGWPVVMVSRNVSQFGYTPEEFLSGTLHYASIIHPEDLDRVIREVRYFSTRGVSHTHHEYRIIAKDGR
VHWVVERSLVERNNKGEIDFFQGVVIDTTERRHMEEELVKAQKLESVGLLAGGIAHDFNNILTGILGNASLAKMLFSPQD
RAYAYVSNIESAAYRAKDLTLQFLTFSKGGAPIKKPVNSVELIRNNTQLALSGLKSTCELSVPDDLRIVEVDEGQISQVI
NNLIINADQAMPRGGVIRVVCENVETSASNGLPLKEGSYVRVSVSDQGAGITAEHRGKIFDPYFTTKDRGHGLGLASAYA
IMKKHAGHICVDSKPGAGATFTIYLPASDAATAITTEEPATAAAGSGRILVMDDEPLVRMVTGEMLEHMGYDVEFAQNGE
EALAMYGAARESGVPFDAVIMDLTVPGGMGGREAIQRIREINPNVRAIVSSGYSDDPVMANHLNYGFAGVVVKPYDLGEL
GAQLERVLRKQE

Sequences:

>Translated_812_residues
MSEYRLSELLDMGIIQKMADTHYRATGIPIGIIDAIDDAVLVGSGWQEICVRFHRAALLSLQRCRESDNYIKSHLVEGQS
CHYRCKNGLNDIGIPIIVAGRHLATMFLGQFFYEEEEPEREYFIQQADEYGFDRDEYLAALDHVPRFSHEKVNNMLEYDK
VLTVFIADLAERSLQKMQAEEETRASERKFHTILDQAYQFIALLSTEGRIQEANRTVLQFGGIEDNCATGKLFWETSWWS
HSPELRKKIRDSVHKVVRGEFIRFEATHPATDGTLQYVDLSLKPVRNPTGAVVLLIAEARDISEQKRVEQALELSNLVVE
NSQVVLFRWKAVEGWPVVMVSRNVSQFGYTPEEFLSGTLHYASIIHPEDLDRVIREVRYFSTRGVSHTHHEYRIIAKDGR
VHWVVERSLVERNNKGEIDFFQGVVIDTTERRHMEEELVKAQKLESVGLLAGGIAHDFNNILTGILGNASLAKMLFSPQD
RAYAYVSNIESAAYRAKDLTLQFLTFSKGGAPIKKPVNSVELIRNNTQLALSGLKSTCELSVPDDLRIVEVDEGQISQVI
NNLIINADQAMPRGGVIRVVCENVETSASNGLPLKEGSYVRVSVSDQGAGITAEHRGKIFDPYFTTKDRGHGLGLASAYA
IMKKHAGHICVDSKPGAGATFTIYLPASDAATAITTEEPATAAAGSGRILVMDDEPLVRMVTGEMLEHMGYDVEFAQNGE
EALAMYGAARESGVPFDAVIMDLTVPGGMGGREAIQRIREINPNVRAIVSSGYSDDPVMANHLNYGFAGVVVKPYDLGEL
GAQLERVLRKQE
>Mature_811_residues
SEYRLSELLDMGIIQKMADTHYRATGIPIGIIDAIDDAVLVGSGWQEICVRFHRAALLSLQRCRESDNYIKSHLVEGQSC
HYRCKNGLNDIGIPIIVAGRHLATMFLGQFFYEEEEPEREYFIQQADEYGFDRDEYLAALDHVPRFSHEKVNNMLEYDKV
LTVFIADLAERSLQKMQAEEETRASERKFHTILDQAYQFIALLSTEGRIQEANRTVLQFGGIEDNCATGKLFWETSWWSH
SPELRKKIRDSVHKVVRGEFIRFEATHPATDGTLQYVDLSLKPVRNPTGAVVLLIAEARDISEQKRVEQALELSNLVVEN
SQVVLFRWKAVEGWPVVMVSRNVSQFGYTPEEFLSGTLHYASIIHPEDLDRVIREVRYFSTRGVSHTHHEYRIIAKDGRV
HWVVERSLVERNNKGEIDFFQGVVIDTTERRHMEEELVKAQKLESVGLLAGGIAHDFNNILTGILGNASLAKMLFSPQDR
AYAYVSNIESAAYRAKDLTLQFLTFSKGGAPIKKPVNSVELIRNNTQLALSGLKSTCELSVPDDLRIVEVDEGQISQVIN
NLIINADQAMPRGGVIRVVCENVETSASNGLPLKEGSYVRVSVSDQGAGITAEHRGKIFDPYFTTKDRGHGLGLASAYAI
MKKHAGHICVDSKPGAGATFTIYLPASDAATAITTEEPATAAAGSGRILVMDDEPLVRMVTGEMLEHMGYDVEFAQNGEE
ALAMYGAARESGVPFDAVIMDLTVPGGMGGREAIQRIREINPNVRAIVSSGYSDDPVMANHLNYGFAGVVVKPYDLGELG
AQLERVLRKQE

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=31.7460317460317, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788549, Length=287, Percent_Identity=29.616724738676, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI48994928, Length=478, Percent_Identity=24.4769874476987, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788713, Length=279, Percent_Identity=26.5232974910394, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=403, Percent_Identity=25.3101736972705, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=26.4367816091954, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790300, Length=298, Percent_Identity=28.1879194630872, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788381, Length=305, Percent_Identity=24.9180327868852, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1786912, Length=277, Percent_Identity=25.2707581227437, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 90485; Mature: 90354

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYRLSELLDMGIIQKMADTHYRATGIPIGIIDAIDDAVLVGSGWQEICVRFHRAALLS
CCCHHHHHHHHHHHHHHHHHCCEEECCCCEEEHHHCCCEEEECCCHHHHHHHHHHHHHHH
LQRCRESDNYIKSHLVEGQSCHYRCKNGLNDIGIPIIVAGRHLATMFLGQFFYEEEEPER
HHHHHCCHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCHH
EYFIQQADEYGFDRDEYLAALDHVPRFSHEKVNNMLEYDKVLTVFIADLAERSLQKMQAE
HHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EETRASERKFHTILDQAYQFIALLSTEGRIQEANRTVLQFGGIEDNCATGKLFWETSWWS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCCCCCEEEEEECCCC
HSPELRKKIRDSVHKVVRGEFIRFEATHPATDGTLQYVDLSLKPVRNPTGAVVLLIAEAR
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCEEEEEEECCC
DISEQKRVEQALELSNLVVENSQVVLFRWKAVEGWPVVMVSRNVSQFGYTPEEFLSGTLH
CCHHHHHHHHHHHHHHHEEECCEEEEEEEEECCCCEEEEEECCHHHHCCCHHHHHCCHHH
YASIIHPEDLDRVIREVRYFSTRGVSHTHHEYRIIAKDGRVHWVVERSLVERNNKGEIDF
HHEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEHHHHHCCCCCCEEE
FQGVVIDTTERRHMEEELVKAQKLESVGLLAGGIAHDFNNILTGILGNASLAKMLFSPQD
ECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
RAYAYVSNIESAAYRAKDLTLQFLTFSKGGAPIKKPVNSVELIRNNTQLALSGLKSTCEL
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHCCCCHHHHHHCCCHHHHHCCCCCEEE
SVPDDLRIVEVDEGQISQVINNLIINADQAMPRGGVIRVVCENVETSASNGLPLKEGSYV
CCCCCCEEEEECCHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEE
RVSVSDQGAGITAEHRGKIFDPYFTTKDRGHGLGLASAYAIMKKHAGHICVDSKPGAGAT
EEEECCCCCCCCHHCCCCEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEE
FTIYLPASDAATAITTEEPATAAAGSGRILVMDDEPLVRMVTGEMLEHMGYDVEFAQNGE
EEEEEECCCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCH
EALAMYGAARESGVPFDAVIMDLTVPGGMGGREAIQRIREINPNVRAIVSSGYSDDPVMA
HHHHHHHCHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEHEECCCCCCCEEE
NHLNYGFAGVVVKPYDLGELGAQLERVLRKQE
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEYRLSELLDMGIIQKMADTHYRATGIPIGIIDAIDDAVLVGSGWQEICVRFHRAALLS
CCHHHHHHHHHHHHHHHHHCCEEECCCCEEEHHHCCCEEEECCCHHHHHHHHHHHHHHH
LQRCRESDNYIKSHLVEGQSCHYRCKNGLNDIGIPIIVAGRHLATMFLGQFFYEEEEPER
HHHHHCCHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCHH
EYFIQQADEYGFDRDEYLAALDHVPRFSHEKVNNMLEYDKVLTVFIADLAERSLQKMQAE
HHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EETRASERKFHTILDQAYQFIALLSTEGRIQEANRTVLQFGGIEDNCATGKLFWETSWWS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCCCCCEEEEEECCCC
HSPELRKKIRDSVHKVVRGEFIRFEATHPATDGTLQYVDLSLKPVRNPTGAVVLLIAEAR
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCEEEEEEECCC
DISEQKRVEQALELSNLVVENSQVVLFRWKAVEGWPVVMVSRNVSQFGYTPEEFLSGTLH
CCHHHHHHHHHHHHHHHEEECCEEEEEEEEECCCCEEEEEECCHHHHCCCHHHHHCCHHH
YASIIHPEDLDRVIREVRYFSTRGVSHTHHEYRIIAKDGRVHWVVERSLVERNNKGEIDF
HHEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEHHHHHCCCCCCEEE
FQGVVIDTTERRHMEEELVKAQKLESVGLLAGGIAHDFNNILTGILGNASLAKMLFSPQD
ECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
RAYAYVSNIESAAYRAKDLTLQFLTFSKGGAPIKKPVNSVELIRNNTQLALSGLKSTCEL
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHCCCCHHHHHHCCCHHHHHCCCCCEEE
SVPDDLRIVEVDEGQISQVINNLIINADQAMPRGGVIRVVCENVETSASNGLPLKEGSYV
CCCCCCEEEEECCHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEE
RVSVSDQGAGITAEHRGKIFDPYFTTKDRGHGLGLASAYAIMKKHAGHICVDSKPGAGAT
EEEECCCCCCCCHHCCCCEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEE
FTIYLPASDAATAITTEEPATAAAGSGRILVMDDEPLVRMVTGEMLEHMGYDVEFAQNGE
EEEEEECCCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCH
EALAMYGAARESGVPFDAVIMDLTVPGGMGGREAIQRIREINPNVRAIVSSGYSDDPVMA
HHHHHHHCHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEHEECCCCCCCEEE
NHLNYGFAGVVVKPYDLGELGAQLERVLRKQE
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA