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The map label for this gene is rho [H]

Identifier: 118581063

GI number: 118581063

Start: 2878038

End: 2879285

Strand: Reverse

Name: rho [H]

Synonym: Ppro_2651

Alternate gene names: 118581063

Gene position: 2879285-2878038 (Counterclockwise)

Preceding gene: 118581066

Following gene: 118581062

Centisome position: 71.84

GC content: 52.4

Gene sequence:

>1248_bases
ATGAACTTACAGGAACTGAAAGGCAAGAAGATCAACGAGCTTAACGCCATTGCCCGTGATCTTAGTATTGAGGGCGCATC
AAGCTTGCGCAAGCAGGATCTCATCTTTGCCATCCTTAACGCGCAGACCGAACAGAACGGCATGATCTTTGGCGAAGGTG
TGCTTGAAACTCTCCAAGACGGCTTTGGGTTTTTACGGGCTACGGATTATAATTATCTGCCGGGTCCAGATGACATCTAC
GTTTCGCCGAGTCAGATCAGGCGTTTTAATCTGCGTACTGGAGACACCGTCTCTGGACAGATTCGGCCTCCCAAGGAGGG
TGAACGTTATTTCGCTCTGCTCAAGGTGGAGTCCGTCAACTTCGAGTCACCTGAAGTCGCCCGGGAAAAAATCCTGTTTG
ACAACCTGACCCCGCTCTATCCTGAGGAAAAGCTGAAGCTGGAAACCGGTGCCGACAACCTTCCCATGCGTGTTGTCGAG
TTGATGGCTCCCATCGGTAAGGGGCAGCGCGGCCTGATCGTTGCGCCACCTCGCACCGGCAAGACAATGCTGATCCAGAA
TATTGCAAACTCCATTGCCGCCAATCATCCGGAAGTCTATCTGATCGTACTGCTGATTGACGAGCGTCCAGAAGAGGTTA
CGGACATGCAGCGTTCGGTAAACGGCGAGGTGGTTTCCTCCACCTTTGACGAACCGGCGACACGCCACGTCCAGGTGGCT
GAAATGGTCATCGAAAAGGCCAAGCGACTGGTGGAGCACAAGCGGGACGTGGTTATCCTGCTGGATTCGATAACACGTCT
TGCGCGTGCATACAATACCGTTATTCCTCCTTCTGGCAAGATTCTCTCCGGAGGTGTGGACTCCAATGCTCTGCACAAAC
CCAAGCGTTTCTTCGGTGCTGCCCGCAATATCGAGGAAGGTGGTTCTCTGACCATCATTGCCACAGCACTGGTGGATACC
GGCAGCAAGATGGACGAGGTTATCTTCGAGGAATTCAAGGGTACCGGCAACATGGAACTGCACTTGGATCGCAAACTTGT
TGAAAAGAGGACGTTTCCCGCCATTGATATCAACAAGTCCGGAACTCGCAAGGAAGAACTGCTGATCGACAAGAACTCCC
TGAACCGCATCTGGATTCTGCGCAAGGTCATCCACCCCATGAATGTTGTGGACAGCATGGAATTCCTTCTGGACAAGCTC
TCAGAGGCGAAGACCAACCAGGCATTTCTGGATTCCATGTCCAAGTGA

Upstream 100 bases:

>100_bases
ACCCACTGAAACCCTATATGGCATTCACCAACCCCGCCATGCTGAAAATCAACTTTTGCAGCCGCATAAACGCATGTTCC
ACTCACATGCAGGAGAACCG

Downstream 100 bases:

>100_bases
AAAAATAGGTTGTAAATAAATTCCCAAATCGCTAACATCAAACTTTGGTAGATCGTTGCTTGCGGTTGTTTCCGCGGCAC
TCGATTAATATGAAGGAGGA

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MNLQELKGKKINELNAIARDLSIEGASSLRKQDLIFAILNAQTEQNGMIFGEGVLETLQDGFGFLRATDYNYLPGPDDIY
VSPSQIRRFNLRTGDTVSGQIRPPKEGERYFALLKVESVNFESPEVAREKILFDNLTPLYPEEKLKLETGADNLPMRVVE
LMAPIGKGQRGLIVAPPRTGKTMLIQNIANSIAANHPEVYLIVLLIDERPEEVTDMQRSVNGEVVSSTFDEPATRHVQVA
EMVIEKAKRLVEHKRDVVILLDSITRLARAYNTVIPPSGKILSGGVDSNALHKPKRFFGAARNIEEGGSLTIIATALVDT
GSKMDEVIFEEFKGTGNMELHLDRKLVEKRTFPAIDINKSGTRKEELLIDKNSLNRIWILRKVIHPMNVVDSMEFLLDKL
SEAKTNQAFLDSMSK

Sequences:

>Translated_415_residues
MNLQELKGKKINELNAIARDLSIEGASSLRKQDLIFAILNAQTEQNGMIFGEGVLETLQDGFGFLRATDYNYLPGPDDIY
VSPSQIRRFNLRTGDTVSGQIRPPKEGERYFALLKVESVNFESPEVAREKILFDNLTPLYPEEKLKLETGADNLPMRVVE
LMAPIGKGQRGLIVAPPRTGKTMLIQNIANSIAANHPEVYLIVLLIDERPEEVTDMQRSVNGEVVSSTFDEPATRHVQVA
EMVIEKAKRLVEHKRDVVILLDSITRLARAYNTVIPPSGKILSGGVDSNALHKPKRFFGAARNIEEGGSLTIIATALVDT
GSKMDEVIFEEFKGTGNMELHLDRKLVEKRTFPAIDINKSGTRKEELLIDKNSLNRIWILRKVIHPMNVVDSMEFLLDKL
SEAKTNQAFLDSMSK
>Mature_415_residues
MNLQELKGKKINELNAIARDLSIEGASSLRKQDLIFAILNAQTEQNGMIFGEGVLETLQDGFGFLRATDYNYLPGPDDIY
VSPSQIRRFNLRTGDTVSGQIRPPKEGERYFALLKVESVNFESPEVAREKILFDNLTPLYPEEKLKLETGADNLPMRVVE
LMAPIGKGQRGLIVAPPRTGKTMLIQNIANSIAANHPEVYLIVLLIDERPEEVTDMQRSVNGEVVSSTFDEPATRHVQVA
EMVIEKAKRLVEHKRDVVILLDSITRLARAYNTVIPPSGKILSGGVDSNALHKPKRFFGAARNIEEGGSLTIIATALVDT
GSKMDEVIFEEFKGTGNMELHLDRKLVEKRTFPAIDINKSGTRKEELLIDKNSLNRIWILRKVIHPMNVVDSMEFLLDKL
SEAKTNQAFLDSMSK

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=418, Percent_Identity=70.5741626794258, Blast_Score=622, Evalue=1e-179,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 46409; Mature: 46409

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQELKGKKINELNAIARDLSIEGASSLRKQDLIFAILNAQTEQNGMIFGEGVLETLQD
CCHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEEEEECCCCCCCEEEEHHHHHHHHH
GFGFLRATDYNYLPGPDDIYVSPSQIRRFNLRTGDTVSGQIRPPKEGERYFALLKVESVN
CCCEEEECCCCCCCCCCCEEECHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCC
FESPEVAREKILFDNLTPLYPEEKLKLETGADNLPMRVVELMAPIGKGQRGLIVAPPRTG
CCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCC
KTMLIQNIANSIAANHPEVYLIVLLIDERPEEVTDMQRSVNGEVVSSTFDEPATRHVQVA
CHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCCEECCCCCCCHHHHHHHH
EMVIEKAKRLVEHKRDVVILLDSITRLARAYNTVIPPSGKILSGGVDSNALHKPKRFFGA
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHCCCHHHHHH
ARNIEEGGSLTIIATALVDTGSKMDEVIFEEFKGTGNMELHLDRKLVEKRTFPAIDINKS
HCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCEEECCCC
GTRKEELLIDKNSLNRIWILRKVIHPMNVVDSMEFLLDKLSEAKTNQAFLDSMSK
CCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC
>Mature Secondary Structure
MNLQELKGKKINELNAIARDLSIEGASSLRKQDLIFAILNAQTEQNGMIFGEGVLETLQD
CCHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEEEEECCCCCCCEEEEHHHHHHHHH
GFGFLRATDYNYLPGPDDIYVSPSQIRRFNLRTGDTVSGQIRPPKEGERYFALLKVESVN
CCCEEEECCCCCCCCCCCEEECHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCC
FESPEVAREKILFDNLTPLYPEEKLKLETGADNLPMRVVELMAPIGKGQRGLIVAPPRTG
CCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCC
KTMLIQNIANSIAANHPEVYLIVLLIDERPEEVTDMQRSVNGEVVSSTFDEPATRHVQVA
CHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCCEECCCCCCCHHHHHHHH
EMVIEKAKRLVEHKRDVVILLDSITRLARAYNTVIPPSGKILSGGVDSNALHKPKRFFGA
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHCCCHHHHHH
ARNIEEGGSLTIIATALVDTGSKMDEVIFEEFKGTGNMELHLDRKLVEKRTFPAIDINKS
HCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCEEECCCC
GTRKEELLIDKNSLNRIWILRKVIHPMNVVDSMEFLLDKLSEAKTNQAFLDSMSK
CCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8051015 [H]