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The map label for this gene is thyX [H]

Identifier: 118581061

GI number: 118581061

Start: 2876913

End: 2877650

Strand: Reverse

Name: thyX [H]

Synonym: Ppro_2649

Alternate gene names: 118581061

Gene position: 2877650-2876913 (Counterclockwise)

Preceding gene: 118581062

Following gene: 118581060

Centisome position: 71.8

GC content: 57.86

Gene sequence:

>738_bases
ATGCTTCCGGGCGCGTGCAACGCCTCCGACCTACCACGGATACCCATGAATATCGAGCTCATTTCCCATACTCCTGAGCC
GGAAAAGAGCGTCGCTCTGGCGGCTAGGCTCTGTTACTCGCCGGCGACGATCGCTGAATTGCGTAAGTCCTTCGATTCCT
CCGACATCGAGTCATTCCTGAATAAAATCATGTCCCTCGGGCATCACTCGGTGCTGGAGCATGCCTCGTTCACCTTTGGA
ATCGAGGGTATCTCCCGCGTGACCTCCCACCAGCTGGTGCGCCACCGCATTGCCTCCTTTTCCCAGCAGTCACAACGCTA
TGTGTCCCATAGTGAGGAATTTTCCTCGATCATGCCCGGTTCCATCGCGGCTAATCCCGAGGCGCGTAGGATCTTCGCCT
TTATGTCCGAGACGCTGCACAAGGCCTATTCCCAGTTGGTGGATATGGGTATTCCCCCCGAGGATGCGCGCTATGTGCTG
CCCAACGCCACCGAGACCAAGCTGGTCATGAGCATGAATGCCCGAGAACTGCTGCATTTCTTCGCGTTGCGCTGCTGCCG
GCGGGCACAGTGGGAGATACGCGAGATGGCCGTGGAGATGCTGCGGCTGGTGAAAAAAGTCGCTCCGGTGATCTTTCGCC
AAGCCGGTCCCGGCTGTGTCAACGGTCCCTGTCCGGAGGGGCCGTTCTGTTGTGGTCAGGCCGATGGGGTGCGCGACTAT
TTCAAAAAACTGGAATAA

Upstream 100 bases:

>100_bases
CGCTACGGCCAAGTATAGAAACGTTCAGCACCACAAGGGAGAGGGGGTTTTGTCGCCGGGCGAAATCCCCTTTTTCTGTT
CTCCGGCAGGATGCGAAGAT

Downstream 100 bases:

>100_bases
ATCGTACACTCCGACCCGAGGTGCAGGCGTGTTGGTTGCGGATGCGTTTCGGGGCGTTACGTGCAGGGCACGTTTTCACC
GTGCGCTTTCACCGCGTTTG

Product: FAD-dependent thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MLPGACNASDLPRIPMNIELISHTPEPEKSVALAARLCYSPATIAELRKSFDSSDIESFLNKIMSLGHHSVLEHASFTFG
IEGISRVTSHQLVRHRIASFSQQSQRYVSHSEEFSSIMPGSIAANPEARRIFAFMSETLHKAYSQLVDMGIPPEDARYVL
PNATETKLVMSMNARELLHFFALRCCRRAQWEIREMAVEMLRLVKKVAPVIFRQAGPGCVNGPCPEGPFCCGQADGVRDY
FKKLE

Sequences:

>Translated_245_residues
MLPGACNASDLPRIPMNIELISHTPEPEKSVALAARLCYSPATIAELRKSFDSSDIESFLNKIMSLGHHSVLEHASFTFG
IEGISRVTSHQLVRHRIASFSQQSQRYVSHSEEFSSIMPGSIAANPEARRIFAFMSETLHKAYSQLVDMGIPPEDARYVL
PNATETKLVMSMNARELLHFFALRCCRRAQWEIREMAVEMLRLVKKVAPVIFRQAGPGCVNGPCPEGPFCCGQADGVRDY
FKKLE
>Mature_245_residues
MLPGACNASDLPRIPMNIELISHTPEPEKSVALAARLCYSPATIAELRKSFDSSDIESFLNKIMSLGHHSVLEHASFTFG
IEGISRVTSHQLVRHRIASFSQQSQRYVSHSEEFSSIMPGSIAANPEARRIFAFMSETLHKAYSQLVDMGIPPEDARYVL
PNATETKLVMSMNARELLHFFALRCCRRAQWEIREMAVEMLRLVKKVAPVIFRQAGPGCVNGPCPEGPFCCGQADGVRDY
FKKLE

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 27372; Mature: 27372

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPGACNASDLPRIPMNIELISHTPEPEKSVALAARLCYSPATIAELRKSFDSSDIESFL
CCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHH
NKIMSLGHHSVLEHASFTFGIEGISRVTSHQLVRHRIASFSQQSQRYVSHSEEFSSIMPG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SIAANPEARRIFAFMSETLHKAYSQLVDMGIPPEDARYVLPNATETKLVMSMNARELLHF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHCCHHHHHHH
FALRCCRRAQWEIREMAVEMLRLVKKVAPVIFRQAGPGCVNGPCPEGPFCCGQADGVRDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHH
FKKLE
HHHCC
>Mature Secondary Structure
MLPGACNASDLPRIPMNIELISHTPEPEKSVALAARLCYSPATIAELRKSFDSSDIESFL
CCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHH
NKIMSLGHHSVLEHASFTFGIEGISRVTSHQLVRHRIASFSQQSQRYVSHSEEFSSIMPG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SIAANPEARRIFAFMSETLHKAYSQLVDMGIPPEDARYVLPNATETKLVMSMNARELLHF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHCCHHHHHHH
FALRCCRRAQWEIREMAVEMLRLVKKVAPVIFRQAGPGCVNGPCPEGPFCCGQADGVRDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHH
FKKLE
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA