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The map label for this gene is pyrK [H]

Identifier: 118581042

GI number: 118581042

Start: 2857894

End: 2858712

Strand: Reverse

Name: pyrK [H]

Synonym: Ppro_2630

Alternate gene names: 118581042

Gene position: 2858712-2857894 (Counterclockwise)

Preceding gene: 118581043

Following gene: 118581041

Centisome position: 71.33

GC content: 68.5

Gene sequence:

>819_bases
ATGCAGTTCACCTCCATGGTTCTCTCCAATGCCGAGGTCTCGCCCGGCTACCACCGCATGCGCCTGACCGCGCCCCCCGA
ATTCGCTGCTGCACGGGCGGGGCAGTTCGTCATGGTGCGGGTGGGTGGCGGCATCGATCCGCTGCTGCGGCGCCCCTTCG
GCATCTTCGACCTCTCTACCCACACCCCGCTCCACGACGGCGCCGTCAGCCAGCCCTGCTTCGAGATGCTCTACCGGGTG
GTGGGCAAGGGGACCGCGCTCCTCTCCACCCTGCACGCCACCGACCGGCTGGATGTTCTCGGCCCCCTGGGAACGGGGTT
CGACCTGGGAACACCGGGCGCGGAGAAGCTGCTGGTGGGGGGTGGGGTCGGTCTGGCTCCGCTCTACCTGCTGGCCCGCC
ACCTGGTCCAGCAGTCGCCGGTGCGCCTGTTCGCCGGCGGCAGGACCAGGGACGACATCCTCTGTATCACGGAATTCGAG
CGACTGGGGGTGGAGTGCTACGTGGCCACCGAGGACGGCTCCCTGGGTGAGTGCGGGCTGGTGACCGAGGCTTTGGTCAG
CCGTCTGGAGCAGCTGGAAGGTGGGGCGGAGCTCTTCGCCTGCGGACCGCATCCCATGCTTAAGGCCGTGGCTGCCATCG
CCGCCTACCACGCTATACCCTGCCAGGTCTCCCTGGAAGGGTACATGGCCTGCGGTGTGGGCGCCTGCCTGGGGTGCGTT
ACCCCCGGCCACGGGCATACGGCCGAGACCCCCGATTACCGCTGCGTCTGCAAGGAGGGACCGGTCTTTCCGGCCCATGA
GCTGGGATGGGAGGAGTGA

Upstream 100 bases:

>100_bases
ATGCCCTGCTGATGGAGAAGGAGCTGGTCTGACATTTTCCCGATCTCTGCCCGTTTTTGCGCCCGGCCCCCCATTTCATC
ATTTTCAAGGAGTTACGTTC

Downstream 100 bases:

>100_bases
GACCATGAAGCCAGATATGACCGTCAACCTGGCCGGGCTTGAATTGCGCAATCCGGTGATGACCGCCTCCGGCACCTTCG
GCTATGGCCGGGAATTCGCC

Product: oxidoreductase FAD/NAD(P)-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MQFTSMVLSNAEVSPGYHRMRLTAPPEFAAARAGQFVMVRVGGGIDPLLRRPFGIFDLSTHTPLHDGAVSQPCFEMLYRV
VGKGTALLSTLHATDRLDVLGPLGTGFDLGTPGAEKLLVGGGVGLAPLYLLARHLVQQSPVRLFAGGRTRDDILCITEFE
RLGVECYVATEDGSLGECGLVTEALVSRLEQLEGGAELFACGPHPMLKAVAAIAAYHAIPCQVSLEGYMACGVGACLGCV
TPGHGHTAETPDYRCVCKEGPVFPAHELGWEE

Sequences:

>Translated_272_residues
MQFTSMVLSNAEVSPGYHRMRLTAPPEFAAARAGQFVMVRVGGGIDPLLRRPFGIFDLSTHTPLHDGAVSQPCFEMLYRV
VGKGTALLSTLHATDRLDVLGPLGTGFDLGTPGAEKLLVGGGVGLAPLYLLARHLVQQSPVRLFAGGRTRDDILCITEFE
RLGVECYVATEDGSLGECGLVTEALVSRLEQLEGGAELFACGPHPMLKAVAAIAAYHAIPCQVSLEGYMACGVGACLGCV
TPGHGHTAETPDYRCVCKEGPVFPAHELGWEE
>Mature_272_residues
MQFTSMVLSNAEVSPGYHRMRLTAPPEFAAARAGQFVMVRVGGGIDPLLRRPFGIFDLSTHTPLHDGAVSQPCFEMLYRV
VGKGTALLSTLHATDRLDVLGPLGTGFDLGTPGAEKLLVGGGVGLAPLYLLARHLVQQSPVRLFAGGRTRDDILCITEFE
RLGVECYVATEDGSLGECGLVTEALVSRLEQLEGGAELFACGPHPMLKAVAAIAAYHAIPCQVSLEGYMACGVGACLGCV
TPGHGHTAETPDYRCVCKEGPVFPAHELGWEE

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 28820; Mature: 28820

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFTSMVLSNAEVSPGYHRMRLTAPPEFAAARAGQFVMVRVGGGIDPLLRRPFGIFDLST
CCHHHHHHCCCCCCCCCEEEEECCCCCHHHHCCCCEEEEEECCCCCHHHHCCCCEEECCC
HTPLHDGAVSQPCFEMLYRVVGKGTALLSTLHATDRLDVLGPLGTGFDLGTPGAEKLLVG
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCEEEEE
GGVGLAPLYLLARHLVQQSPVRLFAGGRTRDDILCITEFERLGVECYVATEDGSLGECGL
CCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEHHHCCEEEEEEECCCCCCCHHH
VTEALVSRLEQLEGGAELFACGPHPMLKAVAAIAAYHAIPCQVSLEGYMACGVGACLGCV
HHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHC
TPGHGHTAETPDYRCVCKEGPVFPAHELGWEE
CCCCCCCCCCCCCEEEECCCCCCCHHHCCCCC
>Mature Secondary Structure
MQFTSMVLSNAEVSPGYHRMRLTAPPEFAAARAGQFVMVRVGGGIDPLLRRPFGIFDLST
CCHHHHHHCCCCCCCCCEEEEECCCCCHHHHCCCCEEEEEECCCCCHHHHCCCCEEECCC
HTPLHDGAVSQPCFEMLYRVVGKGTALLSTLHATDRLDVLGPLGTGFDLGTPGAEKLLVG
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCEEEEE
GGVGLAPLYLLARHLVQQSPVRLFAGGRTRDDILCITEFERLGVECYVATEDGSLGECGL
CCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEHHHCCEEEEEEECCCCCCCHHH
VTEALVSRLEQLEGGAELFACGPHPMLKAVAAIAAYHAIPCQVSLEGYMACGVGACLGCV
HHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHC
TPGHGHTAETPDYRCVCKEGPVFPAHELGWEE
CCCCCCCCCCCCCEEEECCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7516791 [H]