Click here to switch to the map view.

The map label for this gene is yeeO [C]

Identifier: 118581038

GI number: 118581038

Start: 2853862

End: 2855265

Strand: Reverse

Name: yeeO [C]

Synonym: Ppro_2626

Alternate gene names: 118581038

Gene position: 2855265-2853862 (Counterclockwise)

Preceding gene: 118581040

Following gene: 118581036

Centisome position: 71.24

GC content: 62.54

Gene sequence:

>1404_bases
ATGCCCGACTCCCTGTTTTACCGTGGGCAGGGGGACAACCTCCGCCTATGGGCGGTGAGGAGAACAGGCGTGTCAAAACT
GGTCAGTGAGGGCGTATTCACAACAATCATCAAGATGGCCATCCCCATGCTTGCCGGGACGTTTGCCATGAACATGTACA
ACCTTACCAATGCCTGGTTTGTGGCCAAGCTGGGTACCGAGGCGCTGGCGGCCATATCCTTCACCTTTCCGGTGGTCATG
CTGCTCATGTTCGTGACCCGGGGCTTAAGCGGCGGCGCCTTGACGCTGGTGGCTCACGCCATCGGCGCTAAGGACCGCGC
AAAAGCCGCCACCCTCACCACCCATGCCCTGATCCTCGCCGCACTGTTCGGCGCTCTGGTCTGCGGCCTGGGGCTTGTCA
CCGTCTCCCCCCTCTTTTCCCGGTTGGGGGCTTCCGGCCAGGTGCTGGAGATGACCGTGCGCTACATGAACCTGTGGTAC
CTGGGGGCCGCGGTCATGACGTTGCAGATCGTCGCCGCGGACATCATCATCAGCACCGGCAACACCCGGGCAGTCAGTTG
CCTGATGGTGGGCAGCACGCTGGTGAACGTGTTCCTGGACATGGGGCTGATATTCGGAAAGTTCGGCATGCCTAACATGG
GGATCGCGGGCGCCGCCCTGGCGACGATCATCTCCCAGTTGCTGGCCCTGGCGGCGGCACTGTACATCCTGGCCAGCAGG
ATGGGGCTTGTCGATCCGTCGCATCTGGCGCCGGGGGCGCTGTTCAGTTCCTGGAGCAGGATTCTCGCCTTCGGCGTGCC
TGGCGCCCTGGGCATGATACTGACCCCCATATCGTCCGCGGTGATCACCCGGCTCGCGGCCGGTTACGGCAATAGCGCGG
TGGCGGCCATGGGGGTGGCTTCGCGGATAGAGATGTTCGCCTTCATGATCCCCATGACCGTGGGCATGTCGCTGATTCCC
TTTGTGGCCCAGAACTTCGGGGCGGGCAGGATCGACCGGATCAGGACGGCGCGGCACGGGACCATGACCTTCGCCGTCCT
GTACGGCGTCTTCATCGGCCTTGTGTTCATCCTTTTCGCGCCGGCCATGGCCGGACTCTTCTCCACGGAACAAGCGGTTG
TGGATGTGCTCTGCTCCTACATCTACATTACCTGCATGGGCTACGGCATGCTGGAGGTGCATCGCTATGCCGGATTTATC
GTCACCGGCGCCCATTACCCCCTGCAGGCATCCCTGCTCAACGTGATTCGGGTGCTGGTTCTGCTGATCCCCCTTTCCTT
GGCCGGCAGTTACCTGTTCCAGCTCAGGGGGATCTTCTTCGGCAGGCTGGCCACCGACATGCTGGCCGGGATGACCGGGA
TCTGGTGGTCAGGCAGGATGCTGTCCAGGAGGAGGTCAGCCTGA

Upstream 100 bases:

>100_bases
CCTGGTTTTCGCGGACTTCAAAACCGGTGGAGGACAAGGATTTCTGTGGTTGGGTAAATGTTTTGTGTCCATTTAAACGT
AAAACAGGGAGTTGGGTGCG

Downstream 100 bases:

>100_bases
CGGCTGCTCAGCCGCGAAAGCCCTGCGCTCTGGCCTCCGCTATCAGTGCCTGTCGACTGCCGTTGAACACCACGTCAACA
TGCTCTTTGGTGGCCTGCCT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MPDSLFYRGQGDNLRLWAVRRTGVSKLVSEGVFTTIIKMAIPMLAGTFAMNMYNLTNAWFVAKLGTEALAAISFTFPVVM
LLMFVTRGLSGGALTLVAHAIGAKDRAKAATLTTHALILAALFGALVCGLGLVTVSPLFSRLGASGQVLEMTVRYMNLWY
LGAAVMTLQIVAADIIISTGNTRAVSCLMVGSTLVNVFLDMGLIFGKFGMPNMGIAGAALATIISQLLALAAALYILASR
MGLVDPSHLAPGALFSSWSRILAFGVPGALGMILTPISSAVITRLAAGYGNSAVAAMGVASRIEMFAFMIPMTVGMSLIP
FVAQNFGAGRIDRIRTARHGTMTFAVLYGVFIGLVFILFAPAMAGLFSTEQAVVDVLCSYIYITCMGYGMLEVHRYAGFI
VTGAHYPLQASLLNVIRVLVLLIPLSLAGSYLFQLRGIFFGRLATDMLAGMTGIWWSGRMLSRRRSA

Sequences:

>Translated_467_residues
MPDSLFYRGQGDNLRLWAVRRTGVSKLVSEGVFTTIIKMAIPMLAGTFAMNMYNLTNAWFVAKLGTEALAAISFTFPVVM
LLMFVTRGLSGGALTLVAHAIGAKDRAKAATLTTHALILAALFGALVCGLGLVTVSPLFSRLGASGQVLEMTVRYMNLWY
LGAAVMTLQIVAADIIISTGNTRAVSCLMVGSTLVNVFLDMGLIFGKFGMPNMGIAGAALATIISQLLALAAALYILASR
MGLVDPSHLAPGALFSSWSRILAFGVPGALGMILTPISSAVITRLAAGYGNSAVAAMGVASRIEMFAFMIPMTVGMSLIP
FVAQNFGAGRIDRIRTARHGTMTFAVLYGVFIGLVFILFAPAMAGLFSTEQAVVDVLCSYIYITCMGYGMLEVHRYAGFI
VTGAHYPLQASLLNVIRVLVLLIPLSLAGSYLFQLRGIFFGRLATDMLAGMTGIWWSGRMLSRRRSA
>Mature_466_residues
PDSLFYRGQGDNLRLWAVRRTGVSKLVSEGVFTTIIKMAIPMLAGTFAMNMYNLTNAWFVAKLGTEALAAISFTFPVVML
LMFVTRGLSGGALTLVAHAIGAKDRAKAATLTTHALILAALFGALVCGLGLVTVSPLFSRLGASGQVLEMTVRYMNLWYL
GAAVMTLQIVAADIIISTGNTRAVSCLMVGSTLVNVFLDMGLIFGKFGMPNMGIAGAALATIISQLLALAAALYILASRM
GLVDPSHLAPGALFSSWSRILAFGVPGALGMILTPISSAVITRLAAGYGNSAVAAMGVASRIEMFAFMIPMTVGMSLIPF
VAQNFGAGRIDRIRTARHGTMTFAVLYGVFIGLVFILFAPAMAGLFSTEQAVVDVLCSYIYITCMGYGMLEVHRYAGFIV
TGAHYPLQASLLNVIRVLVLLIPLSLAGSYLFQLRGIFFGRLATDMLAGMTGIWWSGRMLSRRRSA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=379, Percent_Identity=21.3720316622691, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49685; Mature: 49554

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSLFYRGQGDNLRLWAVRRTGVSKLVSEGVFTTIIKMAIPMLAGTFAMNMYNLTNAWF
CCCCCEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VAKLGTEALAAISFTFPVVMLLMFVTRGLSGGALTLVAHAIGAKDRAKAATLTTHALILA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALFGALVCGLGLVTVSPLFSRLGASGQVLEMTVRYMNLWYLGAAVMTLQIVAADIIISTG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
NTRAVSCLMVGSTLVNVFLDMGLIFGKFGMPNMGIAGAALATIISQLLALAAALYILASR
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MGLVDPSHLAPGALFSSWSRILAFGVPGALGMILTPISSAVITRLAAGYGNSAVAAMGVA
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SRIEMFAFMIPMTVGMSLIPFVAQNFGAGRIDRIRTARHGTMTFAVLYGVFIGLVFILFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
PAMAGLFSTEQAVVDVLCSYIYITCMGYGMLEVHRYAGFIVTGAHYPLQASLLNVIRVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHH
LLIPLSLAGSYLFQLRGIFFGRLATDMLAGMTGIWWSGRMLSRRRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
PDSLFYRGQGDNLRLWAVRRTGVSKLVSEGVFTTIIKMAIPMLAGTFAMNMYNLTNAWF
CCCCEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VAKLGTEALAAISFTFPVVMLLMFVTRGLSGGALTLVAHAIGAKDRAKAATLTTHALILA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALFGALVCGLGLVTVSPLFSRLGASGQVLEMTVRYMNLWYLGAAVMTLQIVAADIIISTG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
NTRAVSCLMVGSTLVNVFLDMGLIFGKFGMPNMGIAGAALATIISQLLALAAALYILASR
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MGLVDPSHLAPGALFSSWSRILAFGVPGALGMILTPISSAVITRLAAGYGNSAVAAMGVA
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SRIEMFAFMIPMTVGMSLIPFVAQNFGAGRIDRIRTARHGTMTFAVLYGVFIGLVFILFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
PAMAGLFSTEQAVVDVLCSYIYITCMGYGMLEVHRYAGFIVTGAHYPLQASLLNVIRVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHH
LLIPLSLAGSYLFQLRGIFFGRLATDMLAGMTGIWWSGRMLSRRRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]