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The map label for this gene is int [H]

Identifier: 118581028

GI number: 118581028

Start: 2846104

End: 2847510

Strand: Reverse

Name: int [H]

Synonym: Ppro_2616

Alternate gene names: 118581028

Gene position: 2847510-2846104 (Counterclockwise)

Preceding gene: 118581030

Following gene: 118581017

Centisome position: 71.05

GC content: 53.59

Gene sequence:

>1407_bases
ATGCTACTTATTCCGAATGCCATGTTTACCGGCTATGTTGCGCATCTCAATACGCGGGGAATCGACGCTGCCATTCATGC
GGAGTACAAAAAGTGGCTGCGGTATTATCTTGATTTCTGCGATAAGTATCCGGTTCCTGAATCCAAGTCAGAACGTGTTC
GGCTGTTCTGCGAAAAACTGCGGGAGAAGAAACAGTCTGACAATCAGCGACAGCGGGCTGCCCATGCCGTCTCGCTCTAT
TTTGAGATGAAGCAAGAGGAAGAATACACGAAAGTTCGGGAACGTTACTCTCTTGAGGCGGGTGCCGGAACAGTAGCGGA
ATTGAAAGAATATGAAATGTCGGCCCCGGCTGAGTCTCAATCTGTTCCCGATGAAACAGAACGCCTCATCGTCAGGAGAA
GTCCATCTCAGTATACCGAGGCTGGATATCAGGAAAAATCAAAATCACCGGAATGGGATGCACTGCTGGCCACGATGGCG
GCAGAAATCAAGGTGCGCCATTATTCCCGCAAGACGTTGAAAACCTATGCCAACTGGTCCCGGCAGTTCCAGCGCTTCCT
GAAGGATAAGTCACCACAGGAACTTGCGACCGCTGATGTGAAGGAATATATGACGTACCTGGCGGTACAATGCAAAGTTG
CGGCATCAACCCAGAATCAGGCATTCAATGCCCTATTGTTTCTCTATCGCCACGGCTTGAAACGGGAATTCGGTGAGCTG
CGCGACGTGCCACGGGCAAAAAAGTCTTTGTATATCCCGGTCGTTCTTTCCCGGCCCGAGATCGACGCCATCCTTGCCCA
GCTCTCCTATCCGTTTAATCTGGTGGTGAAGCTGCTGTTCGGCTGCGGATTGCGGCAGTTCGAGTGTCTTCAACTGAGGG
TGCGGGATTTCAATTTTGACGCCGGCATTCTTACCATCCACGGCAAGGGGAAGAAGGATCGCACCGTGCCGTTGCCGGAG
TCGCTCGTGCCGGAATTGCGAGCGCAGATCAAGGTGGTTGGCGAACTGCATGACCGGGACCTGAGCGCCGGGTACGATGG
AGTGTTTCTGGATGACGCTGTGGAGAAGAAATACCCCAAGGCGCCCAAGGAGTTCGTCCACCAGTGGTTTTTCCCTCAGA
AGAATCTGACCCTGGTTGCGGAAACCGGCCAGCGTCGGCGCTGGCATTTGCATGAATCGGAGCTTCAGGAGGCGCTCTAT
CCGGCGGTGCGCAGGGCTAAAATCCCCAAGAGGGTAACATCACACACTTTCCGTCACTCATTTGCCACTCACCTGCTGCA
GGCCGGTTACGATATCCGCGTGATTCAAACCCTGTTGGGACATTCCAGCCTGAAAACCACCATGATCTACACCCACTGCG
TGCCGGTCAGGACGGTGAAAGAGCCGAAGAGCCCGCTGGATTTCTGA

Upstream 100 bases:

>100_bases
CCTGGCTCAGTTGGTGATCTTGATATGCAACACAATATAGGCACGAGTTAATTAGTGGGCAATATAGTCTGAAGTAAAAA
CAATGTCAAAGGAGATTGGC

Downstream 100 bases:

>100_bases
TTGGGAGAATCGGTAGGGCCGTGGAGATGTGGGGCAGGCTTGGCTTTATTCGATATATTGGGAGGTTACCCCCCCCAGGC
GGACCAGCAGCCGCTCGGAT

Product: integron integrase

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MLLIPNAMFTGYVAHLNTRGIDAAIHAEYKKWLRYYLDFCDKYPVPESKSERVRLFCEKLREKKQSDNQRQRAAHAVSLY
FEMKQEEEYTKVRERYSLEAGAGTVAELKEYEMSAPAESQSVPDETERLIVRRSPSQYTEAGYQEKSKSPEWDALLATMA
AEIKVRHYSRKTLKTYANWSRQFQRFLKDKSPQELATADVKEYMTYLAVQCKVAASTQNQAFNALLFLYRHGLKREFGEL
RDVPRAKKSLYIPVVLSRPEIDAILAQLSYPFNLVVKLLFGCGLRQFECLQLRVRDFNFDAGILTIHGKGKKDRTVPLPE
SLVPELRAQIKVVGELHDRDLSAGYDGVFLDDAVEKKYPKAPKEFVHQWFFPQKNLTLVAETGQRRRWHLHESELQEALY
PAVRRAKIPKRVTSHTFRHSFATHLLQAGYDIRVIQTLLGHSSLKTTMIYTHCVPVRTVKEPKSPLDF

Sequences:

>Translated_468_residues
MLLIPNAMFTGYVAHLNTRGIDAAIHAEYKKWLRYYLDFCDKYPVPESKSERVRLFCEKLREKKQSDNQRQRAAHAVSLY
FEMKQEEEYTKVRERYSLEAGAGTVAELKEYEMSAPAESQSVPDETERLIVRRSPSQYTEAGYQEKSKSPEWDALLATMA
AEIKVRHYSRKTLKTYANWSRQFQRFLKDKSPQELATADVKEYMTYLAVQCKVAASTQNQAFNALLFLYRHGLKREFGEL
RDVPRAKKSLYIPVVLSRPEIDAILAQLSYPFNLVVKLLFGCGLRQFECLQLRVRDFNFDAGILTIHGKGKKDRTVPLPE
SLVPELRAQIKVVGELHDRDLSAGYDGVFLDDAVEKKYPKAPKEFVHQWFFPQKNLTLVAETGQRRRWHLHESELQEALY
PAVRRAKIPKRVTSHTFRHSFATHLLQAGYDIRVIQTLLGHSSLKTTMIYTHCVPVRTVKEPKSPLDF
>Mature_468_residues
MLLIPNAMFTGYVAHLNTRGIDAAIHAEYKKWLRYYLDFCDKYPVPESKSERVRLFCEKLREKKQSDNQRQRAAHAVSLY
FEMKQEEEYTKVRERYSLEAGAGTVAELKEYEMSAPAESQSVPDETERLIVRRSPSQYTEAGYQEKSKSPEWDALLATMA
AEIKVRHYSRKTLKTYANWSRQFQRFLKDKSPQELATADVKEYMTYLAVQCKVAASTQNQAFNALLFLYRHGLKREFGEL
RDVPRAKKSLYIPVVLSRPEIDAILAQLSYPFNLVVKLLFGCGLRQFECLQLRVRDFNFDAGILTIHGKGKKDRTVPLPE
SLVPELRAQIKVVGELHDRDLSAGYDGVFLDDAVEKKYPKAPKEFVHQWFFPQKNLTLVAETGQRRRWHLHESELQEALY
PAVRRAKIPKRVTSHTFRHSFATHLLQAGYDIRVIQTLLGHSSLKTTMIYTHCVPVRTVKEPKSPLDF

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 54215; Mature: 54215

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIPNAMFTGYVAHLNTRGIDAAIHAEYKKWLRYYLDFCDKYPVPESKSERVRLFCEKL
CEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
REKKQSDNQRQRAAHAVSLYFEMKQEEEYTKVRERYSLEAGAGTVAELKEYEMSAPAESQ
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
SVPDETERLIVRRSPSQYTEAGYQEKSKSPEWDALLATMAAEIKVRHYSRKTLKTYANWS
CCCCHHHHEEHCCCCCHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQFQRFLKDKSPQELATADVKEYMTYLAVQCKVAASTQNQAFNALLFLYRHGLKREFGEL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHH
RDVPRAKKSLYIPVVLSRPEIDAILAQLSYPFNLVVKLLFGCGLRQFECLQLRVRDFNFD
HCCCHHHHCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
AGILTIHGKGKKDRTVPLPESLVPELRAQIKVVGELHDRDLSAGYDGVFLDDAVEKKYPK
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHCCC
APKEFVHQWFFPQKNLTLVAETGQRRRWHLHESELQEALYPAVRRAKIPKRVTSHTFRHS
CHHHHHHHHCCCCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FATHLLQAGYDIRVIQTLLGHSSLKTTMIYTHCVPVRTVKEPKSPLDF
HHHHHHHCCCCHHHHHHHHCCCCHHHEEEEEECCCCHHCCCCCCCCCC
>Mature Secondary Structure
MLLIPNAMFTGYVAHLNTRGIDAAIHAEYKKWLRYYLDFCDKYPVPESKSERVRLFCEKL
CEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
REKKQSDNQRQRAAHAVSLYFEMKQEEEYTKVRERYSLEAGAGTVAELKEYEMSAPAESQ
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
SVPDETERLIVRRSPSQYTEAGYQEKSKSPEWDALLATMAAEIKVRHYSRKTLKTYANWS
CCCCHHHHEEHCCCCCHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQFQRFLKDKSPQELATADVKEYMTYLAVQCKVAASTQNQAFNALLFLYRHGLKREFGEL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHH
RDVPRAKKSLYIPVVLSRPEIDAILAQLSYPFNLVVKLLFGCGLRQFECLQLRVRDFNFD
HCCCHHHHCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
AGILTIHGKGKKDRTVPLPESLVPELRAQIKVVGELHDRDLSAGYDGVFLDDAVEKKYPK
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHCCC
APKEFVHQWFFPQKNLTLVAETGQRRRWHLHESELQEALYPAVRRAKIPKRVTSHTFRHS
CHHHHHHHHCCCCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FATHLLQAGYDIRVIQTLLGHSSLKTTMIYTHCVPVRTVKEPKSPLDF
HHHHHHHCCCCHHHHHHHHCCCCHHHEEEEEECCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]