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The map label for this gene is wecB [H]

Identifier: 118580863

GI number: 118580863

Start: 2647898

End: 2649007

Strand: Reverse

Name: wecB [H]

Synonym: Ppro_2450

Alternate gene names: 118580863

Gene position: 2649007-2647898 (Counterclockwise)

Preceding gene: 118580864

Following gene: 118580862

Centisome position: 66.09

GC content: 62.7

Gene sequence:

>1110_bases
TTGAAAATACTGAACATCGTCGGTGCTCGCCCGAACTTCATGAAAATGGCCCCGATCATCGAGGCCATGAACGCATATCC
CGAACAGATTAACCATCTCCTCGTCCACACCGGCCAGCACTACGACGAGAAGATGAGCAGCTCCTTCTTCGTCGACCTGG
GCATGCCCAGGCCGGATATCAACCTGGAGGTCGGCTCCGGCTCCCATGCCGAACAGACGGCCAAGATCATGGTCGAATTC
GAAAAAGTCTGCCTGAGGGAGAAGCCCGATCTGGTCATCGTCGTGGGGGATGTCAACTCCACCATGGCCTGCACCATCAC
CGCCAAGAAACTGGGCATTCAGGTGGCCCACGTGGAGGCCGGCCTGCGCTCCCGCGACATGGGCATGCCGGAGGAGATCA
ACCGCCTCTGTACCGACGTGCTCTGCGACTTCCTCTTCACCACCGACCACTTCGCCGACGAGAACCTGCTGGCCGAAGGG
GTAGGGCAGGAGAAGATCCACTTTGTCGGCAACGTCATGATCGACACCCTGCTCAGGCACCGGGAGAAGGCCAAAGAGGT
CGGCCTTGTGGACAGGTGGGGGCTCAAGCCGAAGGGGTTCGCCACCCTGACCCTGCACCGCCCCTCCAATGTGGATGATC
CCGTTGTGCTGGGCGGCCTGCTGGAGGCGCTAGCCGACATATCCCGTCAACTCCCCATCATCTTCCCCATCCACCCCCGC
ACCCGCAAGATGGCCGAACAGTTCGGCCTCAGCCACTTCTTCTCCAGCGGCGACGCAGTCTCCGGGCTCTGGGTCACCGA
GCCCCTGGGGTACCTGGAGTTCCTGCATCTGAACATGAACGCCCGCCTGGTGCTCACCGACAGCGGCGGCCTGCAGGAGG
AGACCACCGTGCTGGGCGTCCCCTGCATCACCATGCGCAACAACACCGAACGCCCCATCACCTGCGAACTGGGCACCAAC
TTCCTGGTGGGGAACGACCCCGCCCGGGTCCTGGAGTGCGCCCGCAAAATCCTCTCCGGCGACCTGCCGCAGGGGAGGGT
GCCGGACAGGTGGGACGGCAGGGCAGCCGAGAGGATCGTACGGGTACTGCTGGATGAAATGGCGTGCTAG

Upstream 100 bases:

>100_bases
GGTACAGGGTTGGCGGGATTTGCTCTGGTCGCGTGGCGACGGGGAGCGAGGAAACGGATTTGAACCTGACGGGAAGGCAC
GATACGAGGAGGAGCAGGCC

Downstream 100 bases:

>100_bases
TACCGCGTAACATCTAAAACCAACCCCCCTCAGTCCCCCCTTGTCAGGGGGGAAGCCTTTAAGTCTCCCCTGATAAGGGG
AGGTTTGGAGGGGTTTGGTG

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MKILNIVGARPNFMKMAPIIEAMNAYPEQINHLLVHTGQHYDEKMSSSFFVDLGMPRPDINLEVGSGSHAEQTAKIMVEF
EKVCLREKPDLVIVVGDVNSTMACTITAKKLGIQVAHVEAGLRSRDMGMPEEINRLCTDVLCDFLFTTDHFADENLLAEG
VGQEKIHFVGNVMIDTLLRHREKAKEVGLVDRWGLKPKGFATLTLHRPSNVDDPVVLGGLLEALADISRQLPIIFPIHPR
TRKMAEQFGLSHFFSSGDAVSGLWVTEPLGYLEFLHLNMNARLVLTDSGGLQEETTVLGVPCITMRNNTERPITCELGTN
FLVGNDPARVLECARKILSGDLPQGRVPDRWDGRAAERIVRVLLDEMAC

Sequences:

>Translated_369_residues
MKILNIVGARPNFMKMAPIIEAMNAYPEQINHLLVHTGQHYDEKMSSSFFVDLGMPRPDINLEVGSGSHAEQTAKIMVEF
EKVCLREKPDLVIVVGDVNSTMACTITAKKLGIQVAHVEAGLRSRDMGMPEEINRLCTDVLCDFLFTTDHFADENLLAEG
VGQEKIHFVGNVMIDTLLRHREKAKEVGLVDRWGLKPKGFATLTLHRPSNVDDPVVLGGLLEALADISRQLPIIFPIHPR
TRKMAEQFGLSHFFSSGDAVSGLWVTEPLGYLEFLHLNMNARLVLTDSGGLQEETTVLGVPCITMRNNTERPITCELGTN
FLVGNDPARVLECARKILSGDLPQGRVPDRWDGRAAERIVRVLLDEMAC
>Mature_369_residues
MKILNIVGARPNFMKMAPIIEAMNAYPEQINHLLVHTGQHYDEKMSSSFFVDLGMPRPDINLEVGSGSHAEQTAKIMVEF
EKVCLREKPDLVIVVGDVNSTMACTITAKKLGIQVAHVEAGLRSRDMGMPEEINRLCTDVLCDFLFTTDHFADENLLAEG
VGQEKIHFVGNVMIDTLLRHREKAKEVGLVDRWGLKPKGFATLTLHRPSNVDDPVVLGGLLEALADISRQLPIIFPIHPR
TRKMAEQFGLSHFFSSGDAVSGLWVTEPLGYLEFLHLNMNARLVLTDSGGLQEETTVLGVPCITMRNNTERPITCELGTN
FLVGNDPARVLECARKILSGDLPQGRVPDRWDGRAAERIVRVLLDEMAC

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=385, Percent_Identity=32.2077922077922, Blast_Score=141, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40961; Mature: 40961

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILNIVGARPNFMKMAPIIEAMNAYPEQINHLLVHTGQHYDEKMSSSFFVDLGMPRPDI
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCCC
NLEVGSGSHAEQTAKIMVEFEKVCLREKPDLVIVVGDVNSTMACTITAKKLGIQVAHVEA
EEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEEHHHCEEEEEECC
GLRSRDMGMPEEINRLCTDVLCDFLFTTDHFADENLLAEGVGQEKIHFVGNVMIDTLLRH
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
REKAKEVGLVDRWGLKPKGFATLTLHRPSNVDDPVVLGGLLEALADISRQLPIIFPIHPR
HHHHHHCCCHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCH
TRKMAEQFGLSHFFSSGDAVSGLWVTEPLGYLEFLHLNMNARLVLTDSGGLQEETTVLGV
HHHHHHHHCHHHHHCCCCCCCCEEEECCCCCEEEEEECCCEEEEEECCCCCCCCCEEEEC
PCITMRNNTERPITCELGTNFLVGNDPARVLECARKILSGDLPQGRVPDRWDGRAAERIV
CEEEECCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
RVLLDEMAC
HHHHHHHCC
>Mature Secondary Structure
MKILNIVGARPNFMKMAPIIEAMNAYPEQINHLLVHTGQHYDEKMSSSFFVDLGMPRPDI
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCCC
NLEVGSGSHAEQTAKIMVEFEKVCLREKPDLVIVVGDVNSTMACTITAKKLGIQVAHVEA
EEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEEHHHCEEEEEECC
GLRSRDMGMPEEINRLCTDVLCDFLFTTDHFADENLLAEGVGQEKIHFVGNVMIDTLLRH
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
REKAKEVGLVDRWGLKPKGFATLTLHRPSNVDDPVVLGGLLEALADISRQLPIIFPIHPR
HHHHHHCCCHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCH
TRKMAEQFGLSHFFSSGDAVSGLWVTEPLGYLEFLHLNMNARLVLTDSGGLQEETTVLGV
HHHHHHHHCHHHHHCCCCCCCCEEEECCCCCEEEEEECCCEEEEEECCCCCCCCCEEEEC
PCITMRNNTERPITCELGTNFLVGNDPARVLECARKILSGDLPQGRVPDRWDGRAAERIV
CEEEECCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
RVLLDEMAC
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA