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The map label for this gene is dnaQ [H]

Identifier: 118580761

GI number: 118580761

Start: 2535661

End: 2536173

Strand: Reverse

Name: dnaQ [H]

Synonym: Ppro_2346

Alternate gene names: 118580761

Gene position: 2536173-2535661 (Counterclockwise)

Preceding gene: 118580763

Following gene: 118580758

Centisome position: 63.28

GC content: 69.01

Gene sequence:

>513_bases
ATGGAATCAGGTCTGGCTGTCGTCGATGTGGAGACCAGCGGCCTCTCTCCCCGCGGGGGAGGGAGGGTGATCGAGGTCGC
CGCGGTGCTGCTGCGCGAAGGGAAGGTTGTCGGGGAGTTGGAGAGCCTGCTGCGGGTGAACTGTTCCATCCACCCCGCCG
CGGCGCGGGTGCATGGCATAGGGTGGGAGATGCTGCGCCACGCGCCGGAGCCGGAGGACGTCTGGCGCCGGTTCCTGTCA
TTCGTGGGCCGGCGGCCGCTGGTGGCCCACAACGCCCCCTTCGACATGGGGTTCATCCGCCACGAGCTGGCGCTCTTGGG
GCTGCCGCTTGCCAACCGGAGTATCTGCACCCTCAGGATGGCGCGCAGGAGGTTTCCGGAGCTGGCCAGCCACCGGCTGG
AAGCGCTGGCCCGTCACCTGTTGGGTAGCATACCGGAGGATTGCCGCCTGCACCGGGCCCTGGGGGACGCACGCCTGGCT
GCGCGGGTGTGGCTGGCGATGAATGAACCGTAG

Upstream 100 bases:

>100_bases
CCGCTGCCGGTTGTTGGAAAAAATGAGCCGCTTTTTACTGACAAGACGTATTCTGTCGTGGGTGTGTGCTAGGCTGGGGA
TGGCTCATCGGGAGGTGTGT

Downstream 100 bases:

>100_bases
GGGCGGTCTCTGTGGCGGTCCGGCTTTTTCCGGTGGTGTCAGTCCGCGGCCCTGATGGTTGCGATGGGGAGGAAGAGGTG
CATCGATAGGCCGGGGAGGG

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MESGLAVVDVETSGLSPRGGGRVIEVAAVLLREGKVVGELESLLRVNCSIHPAAARVHGIGWEMLRHAPEPEDVWRRFLS
FVGRRPLVAHNAPFDMGFIRHELALLGLPLANRSICTLRMARRRFPELASHRLEALARHLLGSIPEDCRLHRALGDARLA
ARVWLAMNEP

Sequences:

>Translated_170_residues
MESGLAVVDVETSGLSPRGGGRVIEVAAVLLREGKVVGELESLLRVNCSIHPAAARVHGIGWEMLRHAPEPEDVWRRFLS
FVGRRPLVAHNAPFDMGFIRHELALLGLPLANRSICTLRMARRRFPELASHRLEALARHLLGSIPEDCRLHRALGDARLA
ARVWLAMNEP
>Mature_170_residues
MESGLAVVDVETSGLSPRGGGRVIEVAAVLLREGKVVGELESLLRVNCSIHPAAARVHGIGWEMLRHAPEPEDVWRRFLS
FVGRRPLVAHNAPFDMGFIRHELALLGLPLANRSICTLRMARRRFPELASHRLEALARHLLGSIPEDCRLHRALGDARLA
ARVWLAMNEP

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=174, Percent_Identity=34.4827586206897, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1788149, Length=158, Percent_Identity=31.0126582278481, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 18852; Mature: 18852

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESGLAVVDVETSGLSPRGGGRVIEVAAVLLREGKVVGELESLLRVNCSIHPAAARVHGI
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCC
GWEMLRHAPEPEDVWRRFLSFVGRRPLVAHNAPFDMGFIRHELALLGLPLANRSICTLRM
CHHHHHCCCCHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
ARRRFPELASHRLEALARHLLGSIPEDCRLHRALGDARLAARVWLAMNEP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MESGLAVVDVETSGLSPRGGGRVIEVAAVLLREGKVVGELESLLRVNCSIHPAAARVHGI
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCC
GWEMLRHAPEPEDVWRRFLSFVGRRPLVAHNAPFDMGFIRHELALLGLPLANRSICTLRM
CHHHHHCCCCHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
ARRRFPELASHRLEALARHLLGSIPEDCRLHRALGDARLAARVWLAMNEP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]